**************************************************************************************************************************************************************************************************** MOTIFSIM - Motif Similarity Detection Tool Version 2.1 **************************************************************************************************************************************************************************************************** INPUT **************************************************************************************************************************************************************************************************** Input Parameters Number of files: 2 Number of top significant motifs: 10 Number of best matches: 10 Similarity cutoff: >= 0.75 Matching motif database: UniProbe Mus Musculus Phylogenetic tree: Yes Combined similar motifs: Yes Output file type: All Output file format: All Input files and motif counts File name Count of motifs Dataset # PScanChIP_DM05.txt 16 1 RSAT_peak-motifs_DM05.txt 17 2 **************************************************************************************************************************************************************************************************** RESULTS **************************************************************************************************************************************************************************************************** *************************************************************** Combined Motifs for Top Best Match Motif ID 1 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- HNF4A PPARGRXRA Reverse Complement Reverse Complement TGMYCTTTGBCCK TGRCCTKTGHCCKAB ABTGACCTTTGBCCK Direction: Backward Position #: 3 Overlap #: 13 Alignment: TGMYCTTTGBCCK-- TGRCCTKTGHCCKAB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NR2F1 Reverse Complement Reverse Complement RGGBCAAAGGTCABT AKGYYCAAAGRTCA ARGBBCAAAGGTCABT Direction: Forward Position #: 2 Overlap #: 13 Alignment: -RGGBCAAAGGTCABT AKGYYCAAAGRTCA-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NR1H2RXRA Reverse Complement Reverse Complement ABTGACCTTTGVBCMT GTTGACCTTTGACCTTT VBTGACCTTTGACCHTT Direction: Forward Position #: 1 Overlap #: 16 Alignment: ABTGACCTTTGVBCMT- GTTGACCTTTGACCTTT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACTGTGrYrtCACAGTGswsCAcT Reverse Complement Reverse Complement AAHGGTCAAAGGTCAVV AGTGSWSCACTGTGAMAMCACAGTG ARTGGWSMAMKGTSAMMMCACAGTG Direction: Forward Position #: 1 Overlap #: 17 Alignment: AAHGGTCAAAGGTCAVV-------- AGTGSWSCACTGTGAMAMCACAGTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TGGAGCACTGTGACAcCACAGTGg Reverse Complement Reverse Complement CACTGTGRYRTSACYYTYSWCCAMT CCACTGTGVTGTCACAGTGCTCCA CCACTGTGVTGTCACHBTBSWCCAMT Direction: Forward Position #: 2 Overlap #: 23 Alignment: -CACTGTGRYRTSACYYTYSWCCAMT CCACTGTGVTGTCACAGTGCTCCA-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Reverse Complement Original Motif ARTGGWSBABHGTGACAVCACAGTGG VHRGGTCABDBTGMCCTB AVWGGRKCABHGTGACMHCACAGTGG Direction: Forward Position #: 2 Overlap #: 18 Alignment: ARTGGWSBABHGTGACAVCACAGTGG -VHRGGTCABDBTGMCCTB------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TgTGgTGTCACAGTGCTCC Original Motif Original Motif AVWGGRKCABHGTGACMHCACAGTGG TGTGGTGTCACAGTGCTCC TRBKGKGTCACAGTGMYCCCACAGTGG Direction: Forward Position #: 2 Overlap #: 18 Alignment: -AVWGGRKCABHGTGACMHCACAGTGG TGTGGTGTCACAGTGCTCC-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Original Motif Reverse Complement TRBKGKGTCACAGTGMYCCCACAGTGG MGGTCAGGGTGACCTRDBHV TRBKVKGTCASDGTGMCCYVACAGTGG Direction: Forward Position #: 5 Overlap #: 20 Alignment: TRBKGKGTCACAGTGMYCCCACAGTGG ----MGGTCAGGGTGACCTRDBHV--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Original Motif Reverse Complement TRBKVKGTCASDGTGMCCYVACAGTGG GGYGCTGTCCATGGTGCTGAA KRHGCTGTCMVDGKKVCYBVACAGTGG Direction: Forward Position #: 1 Overlap #: 21 Alignment: TRBKVKGTCASDGTGMCCYVACAGTGG GGYGCTGTCCATGGTGCTGAA------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- AgTGCTCCACTGTGgTGTCACAgT Combined Motif Original Motif Original Motif KRHGCTGTCMVDGKKVCYBVACAGTGG AGTGCTCCACTGTGGTGTCACAGT KRHGCTGTCMVDRGTGCTSCACWGTGGTGTCACAGT Direction: Forward Position #: 13 Overlap #: 15 Alignment: KRHGCTGTCMVDGKKVCYBVACAGTGG--------- ------------AGTGCTCCACTGTGGTGTCACAGT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Original Motif Original Motif KRHGCTGTCMVDRGTGCTSCACWGTGGTGTCACAGT YDRCCASYAGRKGGCRSYV BVDSCWSYMVRKGGYRCTVCACWGTGGTGTCACAGT Direction: Forward Position #: 1 Overlap #: 19 Alignment: KRHGCTGTCMVDRGTGCTSCACWGTGGTGTCACAGT YDRCCASYAGRKGGCRSYV----------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 2 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR2F1 NR1H2RXRA Original Motif Reverse Complement TGAMCTTTGMMCYT GTTGACCTTTGACCTTT TTGACCTTTGACCTTGT Direction: Backward Position #: 2 Overlap #: 14 Alignment: --TGAMCTTTGMMCYT- GTTGACCTTTGACCTTT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Reverse Complement Original Motif ACAAGGTCAAAGGTCAA BTRGGDCARAGGKCA ASDRGGKCAAAGGTCAA Direction: Forward Position #: 2 Overlap #: 15 Alignment: ACAAGGTCAAAGGTCAA -BTRGGDCARAGGKCA- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACTGTGrYrtCACAGTGswsCAcT Original Motif Reverse Complement ASDRGGKCAAAGGTCAA AGTGSWSCACTGTGAMAMCACAGTG ASTGGRBCAMWGKKMMAMCACAGTG Direction: Forward Position #: 1 Overlap #: 17 Alignment: ASDRGGKCAAAGGTCAA-------- AGTGSWSCACTGTGAMAMCACAGTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Original Motif Reverse Complement ASTGGRBCAMWGKKMMAMCACAGTG BAGGYCABHBTGACCKHV ASBRGGBCAHHGTGAMMBYACAGTG Direction: Forward Position #: 3 Overlap #: 18 Alignment: ASTGGRBCAMWGKKMMAMCACAGTG --BAGGYCABHBTGACCKHV----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Reverse Complement Original Motif CACTGTKVRRTCACHDTGVCCKVST TTCAGCACCATGGACAGCKCC CCKTBAGVWCMHHGKRCASBDCACTGT Direction: Backward Position #: 3 Overlap #: 19 Alignment: CACTGTKVRRTCACHDTGVCCKVST-- ------TTCAGCACCATGGACAGCKCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 3 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 TGGAGCACTGTGACAcCACAGTGg Original Motif Reverse Complement VDBHMAGGTCACCCTGACCY CCACTGTGVTGTCACAGTGCTCCA ACTGTVRKGTCACMSTGMYCYCCA Direction: Backward Position #: 2 Overlap #: 20 Alignment: ---VDBHMAGGTCACCCTGACCY- CCACTGTGVTGTCACAGTGCTCCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CACTGTGrYrtCACAGTGswsCAcT Combined Motif Original Motif Reverse Complement ACTGTVRKGTCACMSTGMYCYCCA AGTGSWSCACTGTGAMAMCACAGTG ACTRBKGKRKCACWGTGMCMHCMMAGTG Direction: Forward Position #: 4 Overlap #: 21 Alignment: ACTGTVRKGTCACMSTGMYCYCCA---- ---AGTGSWSCACTGTGAMAMCACAGTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TgTGgTGTCACAGTGCTCC Original Motif Original Motif ACTRBKGKRKCACWGTGMCMHCMMAGTG TGTGGTGTCACAGTGCTCC WVTGGTGTVDCASTGYKMCMHCMMAGTG Direction: Forward Position #: 1 Overlap #: 19 Alignment: ACTRBKGKRKCACWGTGMCMHCMMAGTG TGTGGTGTCACAGTGCTCC--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Reverse Complement Original Motif CACTYYGDRGRYMCASTGDVACACCAVW YDRCCASYAGRKGGCRSYV YDRCMMYYWGRGGGCRCHVTGDVACACCAVW Direction: Forward Position #: 4 Overlap #: 16 Alignment: ---CACTYYGDRGRYMCASTGDVACACCAVW YDRCCASYAGRKGGCRSYV------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR2 Reverse Complement Reverse Complement WVTGGTGTVDCAVHGKGCCCMCWKMRRGMHM BAGGYCABHBTGACCKHV BAGDBYRBBGTGACMBHGKGCCCMCWKMRRGMHM Direction: Forward Position #: 4 Overlap #: 15 Alignment: ---WVTGGTGTVDCAVHGKGCCCMCWKMRRGMHM BAGGYCABHBTGACCKHV---------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- REST Combined Motif Original Motif Reverse Complement BAGDBYRBBGTGACMBHGKGCCCMCWKMRRGMHM GGYGCTGTCCATGGTGCTGAA BAGDBBRBBCTGWCCVWGGKSCTVMHKMRRGMHM Direction: Forward Position #: 6 Overlap #: 21 Alignment: BAGDBYRBBGTGACMBHGKGCCCMCWKMRRGMHM -----GGYGCTGTCCATGGTGCTGAA-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- AmTGTGACACCACAGT Combined Motif Original Motif Reverse Complement BAGDBBRBBCTGWCCVWGGKSCTVMHKMRRGMHM ACTGTGGTGTCACART BASTGTGBTGTSACMVTGGKSCTVMHKMRRGMHM Direction: Forward Position #: 2 Overlap #: 16 Alignment: BAGDBBRBBCTGWCCVWGGKSCTVMHKMRRGMHM -ACTGTGGTGTCACART----------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AgTGCTCCACTGTGgTGTCACAgT Reverse Complement Reverse Complement YDRCMMYYHRVAGSRCCAVYGTSACABCACASTB ACTGTGACACCACAGTGGAGCACT ACTGTGACACCAHAGWGGASCACTGTSACABCACASTB Direction: Forward Position #: 5 Overlap #: 20 Alignment: ----YDRCMMYYHRVAGSRCCAVYGTSACABCACASTB ACTGTGACACCACAGTGGAGCACT-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PPARGRXRA Original Motif Reverse Complement ACTGTGACACCAHAGWGGASCACTGTSACABCACASTB TGRCCTKTGHCCKAB TGACYKTKRCMCBABAGWGGASCACTGTSACABCACASTB Direction: Forward Position #: 3 Overlap #: 13 Alignment: --ACTGTGACACCAHAGWGGASCACTGTSACABCACASTB TGRCCTKTGHCCKAB------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NR1H2RXRA Original Motif Reverse Complement TGACYKTKRCMCBABAGWGGASCACTGTSACABCACASTB GTTGACCTTTGACCTTT GTTGACCTTTGMCCTDHAGWGGASCACTGTSACABCACASTB Direction: Forward Position #: 3 Overlap #: 15 Alignment: --TGACYKTKRCMCBABAGWGGASCACTGTSACABCACASTB GTTGACCTTTGACCTTT------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 4 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Esrrb NR2F1 Reverse Complement Original Motif TGACCTTGMBBB TGAMCTTTGMMCYT WSMYYTKRMCHBTG Direction: Backward Position #: 1 Overlap #: 12 Alignment: --TGACCTTGMBBB TGAMCTTTGMMCYT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Reverse Complement Original Motif CAVDGYMYAKKRSW BTRGGDCARAGGKCA CVHRGBVCADRGGTCA Direction: Forward Position #: 2 Overlap #: 13 Alignment: CAVDGYMYAKKRSW-- -BTRGGDCARAGGKCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif HNF4A Reverse Complement Reverse Complement TGACCKHTGVBCMHBG TGMYCTTTGBCCK TGVCCTTTGBHCBHBG Direction: Forward Position #: 1 Overlap #: 13 Alignment: TGACCKHTGVBCMHBG TGMYCTTTGBCCK--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NR1H2RXRA Original Motif Reverse Complement TGVCCTTTGBHCBHBG GTTGACCTTTGACCTTT GTTGACCTTTGACCTDTG Direction: Forward Position #: 3 Overlap #: 15 Alignment: --TGVCCTTTGBHCBHBG GTTGACCTTTGACCTTT- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Original Motif Reverse Complement GTTGACCTTTGACCTDTG MGGTCAGGGTGACCTRDBHV VKKKMMSKBTGACCTDBGHV Direction: Forward Position #: 1 Overlap #: 18 Alignment: GTTGACCTTTGACCTDTG-- MGGTCAGGGTGACCTRDBHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR2 Original Motif Reverse Complement VKKKMMSKBTGACCTDBGHV BAGGYCABHBTGACCKHV VDGGHMMBBTKRMCYKDGHV Direction: Forward Position #: 1 Overlap #: 18 Alignment: VKKKMMSKBTGACCTDBGHV BAGGYCABHBTGACCKHV-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Original Motif Original Motif VDGGHMMBBTKRMCYKDGHV TTCAGCACCATGGACAGCKCC TBHRGHACCHTGGACAGHDVC Direction: Forward Position #: 2 Overlap #: 20 Alignment: -VDGGHMMBBTKRMCYKDGHV TTCAGCACCATGGACAGCKCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TgTGgTGTCACAGTGCTCC Combined Motif Reverse Complement Original Motif GVHDCTGTCCAHGGTDCKDVA TGTGGTGTCACAGTGCTCC GVHDCTGTCCAHKGTGSTGTMACAGTGCTCC Direction: Forward Position #: 13 Overlap #: 9 Alignment: GVHDCTGTCCAHGGTDCKDVA---------- ------------TGTGGTGTCACAGTGCTCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TGGAGCACTGTGACAcCACAGTGg Combined Motif Original Motif Original Motif GVHDCTGTCCAHKGTGSTGTMACAGTGCTCC TGGAGCACTGTGACAVCACAGTGG GVHDYKGWSCAHTGTGVYRHCACAGTGSTCC Direction: Forward Position #: 5 Overlap #: 24 Alignment: GVHDCTGTCCAHKGTGSTGTMACAGTGCTCC ----TGGAGCACTGTGACAVCACAGTGG--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACTGTGrYrtCACAGTGswsCAcT Reverse Complement Reverse Complement GGASCACTGTGHKKBCACADTGSWCYMHDVC AGTGSWSCACTGTGAMAMCACAGTG AGTGGASCACTGTGMHDHCACAGTGSWCYMHDVC Direction: Forward Position #: 4 Overlap #: 22 Alignment: ---GGASCACTGTGHKKBCACADTGSWCYMHDVC AGTGSWSCACTGTGAMAMCACAGTG--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 5 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ZEB1 CTCF Reverse Complement Original Motif HAGGTG YDRCCASYAGRKGGCRSYV YDRCCASYAGGTGGCRSYV Direction: Forward Position #: 8 Overlap #: 6 Alignment: -------HAGGTG------ YDRCCASYAGRKGGCRSYV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RORA_1 Combined Motif Original Motif Reverse Complement YDRCCASYAGGTGGCRSYV TGACCTDVWT YDRCCASYAGGTGRCSBHVWT Direction: Forward Position #: 12 Overlap #: 8 Alignment: YDRCCASYAGGTGGCRSYV-- -----------TGACCTDVWT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Reverse Complement Original Motif AWVHVSGKCACCTKSTGGMHM TTCAGCACCATGGACAGCKCC TTCAGCAYCAHGGDCASCTBSTGGMHM Direction: Forward Position #: 7 Overlap #: 15 Alignment: ------AWVHVSGKCACCTKSTGGMHM TTCAGCACCATGGACAGCKCC------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Esrrb Reverse Complement Reverse Complement YDRCCASBAGSTGDCCHTGKTGCTGAA TGACCTTGMBBB TGACCWKGAGVTGDCCHTGKTGCTGAA Direction: Forward Position #: 1 Overlap #: 12 Alignment: YDRCCASBAGSTGDCCHTGKTGCTGAA TGACCTTGMBBB--------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR1H2RXRA Combined Motif Reverse Complement Original Motif TTCAGCAYCAHGGDCAVCTCRWGGTCA AAAGGTCAAAGGTCAAC TWMAGSWCMAAGGTCAVCTCRWGGTCA Direction: Forward Position #: 2 Overlap #: 17 Alignment: TTCAGCAYCAHGGDCAVCTCRWGGTCA -AAAGGTCAAAGGTCAAC--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PPARGRXRA Reverse Complement Reverse Complement TGACCWKGAGBTGACCTTYGWSCTRWA TGRCCTKTGHCCKAB TGRCCTKKVBBYGACCTTYGWSCTRWA Direction: Forward Position #: 1 Overlap #: 15 Alignment: TGACCWKGAGBTGACCTTYGWSCTRWA TGRCCTKTGHCCKAB------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NR4A2 Original Motif Reverse Complement TGRCCTKKVBBYGACCTTYGWSCTRWA GTGACCTT GTGACCTTKVBBYGACCTTYGWSCTRWA Direction: Forward Position #: 2 Overlap #: 7 Alignment: -TGRCCTKKVBBYGACCTTYGWSCTRWA GTGACCTT-------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Original Motif Original Motif GTGACCTTKVBBYGACCTTYGWSCTRWA VDBHMAGGTCACCCTGACCY VVTBMMSKTYABCYKRMCYTYGWSCTRWA Direction: Forward Position #: 2 Overlap #: 19 Alignment: -GTGACCTTKVBBYGACCTTYGWSCTRWA VDBHMAGGTCACCCTGACCY--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mycn Combined Motif Original Motif Reverse Complement VVTBMMSKTYABCYKRMCYTYGWSCTRWA GCCACGTGSD VGYCACGTKSRBCYKRMCYTYGWSCTRWA Direction: Forward Position #: 2 Overlap #: 10 Alignment: VVTBMMSKTYABCYKRMCYTYGWSCTRWA -GCCACGTGSD------------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Myc Combined Motif Original Motif Reverse Complement VGYCACGTKSRBCYKRMCYTYGWSCTRWA DCCACGTGCV VGCCACGTGSVBCYKRMCYTYGWSCTRWA Direction: Forward Position #: 2 Overlap #: 10 Alignment: VGYCACGTKSRBCYKRMCYTYGWSCTRWA -DCCACGTGCV------------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 6 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mycn Myc Reverse Complement Reverse Complement GCCACGTGSD DCCACGTGCV GCCACGTGSV Direction: Forward Position #: 1 Overlap #: 10 Alignment: GCCACGTGSD DCCACGTGCV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif sscCCCGCGcs Reverse Complement Reverse Complement VSCACGTGGC SBCGCGGGGSB VSCRCGKGGVB Direction: Forward Position #: 1 Overlap #: 10 Alignment: VSCACGTGGC- SBCGCGGGGSB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Reverse Complement Original Motif BVCCYCGMGSV YDRCCASYAGRKGGCRSYV YBVCCHCGAGVKGGCRSYV Direction: Forward Position #: 2 Overlap #: 11 Alignment: -BVCCYCGMGSV------- YDRCCASYAGRKGGCRSYV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCCCCGCSssk Original Motif Reverse Complement YBVCCHCGAGVKGGCRSYV BBSGGCGGGGBS YBSSSCSGRGVBGGCRSYV Direction: Forward Position #: 1 Overlap #: 12 Alignment: YBVCCHCGAGVKGGCRSYV BBSGGCGGGGBS------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACTGTGrYrtCACAGTGswsCAcT Reverse Complement Original Motif BMSMGCCBVCMCSGSSSBM CACTGTGRTRTCACAGTGSWSCACT TCACAGTGSWSCACTBASYGYSVBSBMSMGCCBV Direction: Backward Position #: 16 Overlap #: 10 Alignment: BMSMGCCBVCMCSGSSSBM--------------- ---------CACTGTGRTRTCACAGTGSWSCACT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 7 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- REST AgTGCTCCACTGTGgTGTCACAgT Reverse Complement Original Motif GGYGCTGTCCATGGTGCTGAA AGTGCTCCACTGTGGTGTCACAGT ACAGTRGTGCTSYMCWKKGKKSTSGG Direction: Backward Position #: 6 Overlap #: 19 Alignment: GGYGCTGTCCATGGTGCTGAA----- --AGTGCTCCACTGTGGTGTCACAGT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Reverse Complement Original Motif CCSASRRCRYWGRKSAGCACKACTGT VDBHMAGGTCACCCTGACCY VDVCSAGGDCABHGDGVMSYACKACTGT Direction: Forward Position #: 3 Overlap #: 18 Alignment: --CCSASRRCRYWGRKSAGCACKACTGT VDBHMAGGTCACCCTGACCY-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CagTGCTCCACTGTGgT Combined Motif Reverse Complement Original Motif ACAGTRGTKSYBCDCDBTGDCCTSGVHV CAGTGCTCCACTGTGBT ACAGYAGTGCTCCACTGTGDYCTSGVHV Direction: Forward Position #: 5 Overlap #: 17 Alignment: ACAGTRGTKSYBCDCDBTGDCCTSGVHV ----CAGTGCTCCACTGTGBT------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AmTGTGACACCACAGT Original Motif Reverse Complement ACAGYAGTGCTCCACTGTGDYCTSGVHV ACTGTGGTGTCACART ACWGTRGTGYYMCASTGTGDYCTSGVHV Direction: Forward Position #: 1 Overlap #: 16 Alignment: ACAGYAGTGCTCCACTGTGDYCTSGVHV ACTGTGGTGTCACART------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TGGAGCACTGTGACAcCACAGTGg Original Motif Reverse Complement ACWGTRGTGYYMCASTGTGDYCTSGVHV CCACTGTGVTGTCACAGTGCTCCA MCASTGKKGTBWCACWGTGBTCYRGVHV Direction: Forward Position #: 1 Overlap #: 24 Alignment: ACWGTRGTGYYMCASTGTGDYCTSGVHV CCACTGTGVTGTCACAGTGCTCCA---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Original Motif Original Motif MCASTGKKGTBWCACWGTGBTCYRGVHV VHRGGTCABDBTGMCCTB MCASTGBDRKGTCAVDGTGHYCYVGVHV Direction: Forward Position #: 7 Overlap #: 18 Alignment: MCASTGKKGTBWCACWGTGBTCYRGVHV ------VHRGGTCABDBTGMCCTB---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- HNF4A Combined Motif Reverse Complement Original Motif VDVCBMGKDCACDVTGACRMDVCASTGY RGGBCAAAGKYCA VDVCBVGKBCAMAGTGMVRMDVCASTGY Direction: Forward Position #: 6 Overlap #: 13 Alignment: VDVCBMGKDCACDVTGACRMDVCASTGY -----RGGBCAAAGKYCA---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Original Motif Original Motif VDVCBVGKBCAMAGTGMVRMDVCASTGY BTRGGDCARAGGKCA VDVBBRGGBCAAAGKKCARMDVCASTGY Direction: Forward Position #: 4 Overlap #: 15 Alignment: VDVCBVGKBCAMAGTGMVRMDVCASTGY ---BTRGGDCARAGGKCA---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACTGTGrYrtCACAGTGswsCAcT Original Motif Original Motif VDVBBRGGBCAAAGKKCARMDVCASTGY CACTGTGRTRTCACAGTGSWSCACT CACTGTKRKGBCACAGTGCWVCAVYASTGY Direction: Forward Position #: 3 Overlap #: 23 Alignment: --VDVBBRGGBCAAAGKKCARMDVCASTGY CACTGTGRTRTCACAGTGSWSCACT----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwCCAmAGTCmt Reverse Complement Reverse Complement MCASTMVTGVWGCACTGTGVCYKYACAGTG VDGACTRTGGDD VVSACTRTKGHWGCACTGTGVCYKYACAGTG Direction: Forward Position #: 2 Overlap #: 11 Alignment: -MCASTMVTGVWGCACTGTGVCYKYACAGTG VDGACTRTGGDD------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 8 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Myc Mycn Original Motif Original Motif VGCACGTGGH HSCACGTGGC VSCACGTGGC Direction: Backward Position #: 1 Overlap #: 10 Alignment: VGCACGTGGH HSCACGTGGC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif sscCCCGCGcs Original Motif Reverse Complement VSCACGTGGC SBCGCGGGGSB VSCRCGKGGVB Direction: Forward Position #: 1 Overlap #: 10 Alignment: VSCACGTGGC- SBCGCGGGGSB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCCCCGCSssk Reverse Complement Original Motif BVCCYCGMGSV SBCCCCGCCSBB SBCCCCGCSSBB Direction: Forward Position #: 1 Overlap #: 11 Alignment: BVCCYCGMGSV- SBCCCCGCCSBB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CTCF Combined Motif Original Motif Reverse Complement SBCCCCGCSSBB BMSMGCCYMCTKSTGGMHM SBYCSCGCCCVCTKSTGGMHM Direction: Forward Position #: 3 Overlap #: 10 Alignment: SBCCCCGCSSBB--------- --BMSMGCCYMCTKSTGGMHM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CACTGTGrYrtCACAGTGswsCAcT Combined Motif Original Motif Reverse Complement SBYCSCGCCCVCTKSTGGMHM AGTGSWSCACTGTGAMAMCACAGTG SBYMSYGCHSCMYTGTGRMMMCACAGTG Direction: Forward Position #: 4 Overlap #: 18 Alignment: SBYCSCGCCCVCTKSTGGMHM------- ---AGTGSWSCACTGTGAMAMCACAGTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- HNF4A Combined Motif Original Motif Original Motif SBYMSYGCHSCMYTGTGRMMMCACAGTG RGGBCAAAGKYCA SBYMSYGSDBCAHWGTGVMMMCACAGTG Direction: Forward Position #: 7 Overlap #: 13 Alignment: SBYMSYGCHSCMYTGTGRMMMCACAGTG ------RGGBCAAAGKYCA--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Reverse Complement Reverse Complement CACTGTGYYYVCACWHTGBHSCMSYKBS MGGTCAGGGTGACCTRDBHV MGGTCASKGTGHCCBBRCHHTGBHSCMSYKBS Direction: Forward Position #: 5 Overlap #: 16 Alignment: ----CACTGTGYYYVCACWHTGBHSCMSYKBS MGGTCAGGGTGACCTRDBHV------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CagTGCTCCACTGTGgT Reverse Complement Reverse Complement SBYMSYGSDBCAHHGKBVGGHCACRSTGACCY ABCACAGTGGAGCACTG ABCACAGTGGAGCAHHGKBVGGHCACRSTGACCY Direction: Forward Position #: 3 Overlap #: 15 Alignment: --SBYMSYGSDBCAHHGKBVGGHCACRSTGACCY ABCACAGTGGAGCACTG----------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Original Motif Original Motif ABCACAGTGGAGCAHHGKBVGGHCACRSTGACCY VHRGGTCABDBTGMCCTB ABCACAVTRGRKCABDGTGVBBTCACRSTGACCY Direction: Forward Position #: 7 Overlap #: 18 Alignment: ABCACAGTGGAGCAHHGKBVGGHCACRSTGACCY ------VHRGGTCABDBTGMCCTB---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TGGAGCACTGTGACAcCACAGTGg Reverse Complement Original Motif MGGTCASKGTGABBBCACDBTGRMCMAVTGTGBT TGGAGCACTGTGACAVCACAGTGG TVGRKCACTGTGACABCACAGTGRMCMAVTGTGBT Direction: Forward Position #: 2 Overlap #: 23 Alignment: -MGGTCASKGTGABBBCACDBTGRMCMAVTGTGBT TGGAGCACTGTGACAVCACAGTGG----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 9 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 TGGAGCACTGTGACAcCACAGTGg Original Motif Reverse Complement VHRGGTCABDBTGMCCTB CCACTGTGVTGTCACAGTGCTCCA CCACTGTDRKGTCACAGTGCYCYA Direction: Forward Position #: 7 Overlap #: 18 Alignment: ------VHRGGTCABDBTGMCCTB CCACTGTGVTGTCACAGTGCTCCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACTGTGrYrtCACAGTGswsCAcT Reverse Complement Reverse Complement TKGMGCACTGTGACRMHACAGTGG AGTGSWSCACTGTGAMAMCACAGTG AGTGGAGCACTGTGACAMCACAGTGG Direction: Forward Position #: 3 Overlap #: 23 Alignment: --TKGMGCACTGTGACRMHACAGTGG AGTGSWSCACTGTGAMAMCACAGTG- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- REST Combined Motif Original Motif Original Motif AGTGGAGCACTGTGACAMCACAGTGG TTCAGCACCATGGACAGCKCC AGTGGAGCACTGTGWCAGCACMRTGGACAGCKCC Direction: Forward Position #: 14 Overlap #: 13 Alignment: AGTGGAGCACTGTGACAMCACAGTGG-------- -------------TTCAGCACCATGGACAGCKCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Reverse Complement Original Motif GGYGCTGTCCAMYGTGCTGWCACAGTGCTCCACT VDBHMAGGTCACCCTGACCY GVHBCWGKYCAVYGTGMYSHCACAGTGCTCCACT Direction: Forward Position #: 1 Overlap #: 20 Alignment: GGYGCTGTCCAMYGTGCTGWCACAGTGCTCCACT VDBHMAGGTCACCCTGACCY-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TgTGgTGTCACAGTGCTCC Reverse Complement Original Motif AGTGGAGCACTGTGHSKYCACKVTGKRCWGBDVC TGTGGTGTCACAGTGCTCC TRKKGKDKCACWGTGMBBCCACKVTGKRCWGBDVC Direction: Forward Position #: 2 Overlap #: 18 Alignment: -AGTGGAGCACTGTGHSKYCACKVTGKRCWGBDVC TGTGGTGTCACAGTGCTCC---------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Original Motif Original Motif TRKKGKDKCACWGTGMBBCCACKVTGKRCWGBDVC BTRGGDCARAGGKCA TRKKGTRKSACARWGVTCMCACKVTGKRCWGBDVC Direction: Forward Position #: 5 Overlap #: 15 Alignment: TRKKGKDKCACWGTGMBBCCACKVTGKRCWGBDVC ----BTRGGDCARAGGKCA---------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR2F1 Combined Motif Original Motif Original Motif TRKKGTRKSACARWGVTCMCACKVTGKRCWGBDVC TGAMCTTTGMMCYT TRKKGTKGAMCWDTGVHCHYACKVTGKRCWGBDVC Direction: Forward Position #: 7 Overlap #: 14 Alignment: TRKKGTRKSACARWGVTCMCACKVTGKRCWGBDVC ------TGAMCTTTGMMCYT--------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Tcfcp2l1 Original Motif Reverse Complement TRKKGTKGAMCWDTGVHCHYACKVTGKRCWGBDVC CKGGDTBDMMCTGG YDKGDTDGAMCTKKGVHCHYACKVTGKRCWGBDVC Direction: Forward Position #: 1 Overlap #: 14 Alignment: TRKKGTKGAMCWDTGVHCHYACKVTGKRCWGBDVC CKGGDTBDMMCTGG--------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CTCF Combined Motif Reverse Complement Original Motif GVHBCWGKYCAVYGTKDGHVCYYAGYTCDAHCYHK YDRCCASYAGRKGGCRSYV GVHBCWBKBCMACBWGRGGGCVCHGYTCDAHCYHK Direction: Forward Position #: 7 Overlap #: 19 Alignment: GVHBCWGKYCAVYGTKDGHVCYYAGYTCDAHCYHK ------YDRCCASYAGRKGGCRSYV---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- HNF4A Combined Motif Reverse Complement Original Motif YDKGDTDGAMCHGVGCCCMCWBGTRGBYBWGBDVC RGGBCAAAGKYCA YDGGBYARAVBHSVGCCCMCWBGTRGBYBWGBDVC Direction: Forward Position #: 2 Overlap #: 13 Alignment: YDKGDTDGAMCHGVGCCCMCWBGTRGBYBWGBDVC -RGGBCAAAGKYCA--------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 10 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR1H2RXRA REST Reverse Complement Reverse Complement GTTGACCTTTGACCTTT GGYGCTGTCCATGGTGCTGAA GGYGYTGWCCTTKGWSCTKWA Direction: Forward Position #: 4 Overlap #: 17 Alignment: ---GTTGACCTTTGACCTTT- GGYGCTGTCCATGGTGCTGAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PPARGRXRA Original Motif Reverse Complement GGYGYTGWCCTTKGWSCTKWA TGRCCTKTGHCCKAB TGRSCKYTGHCCTWBGWSCTKWA Direction: Forward Position #: 3 Overlap #: 13 Alignment: --GGYGYTGWCCTTKGWSCTKWA TGRCCTKTGHCCKAB-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Original Motif Original Motif TGRSCKYTGHCCTWBGWSCTKWA VDBHMAGGTCACCCTGACCY DBVBCDKKKCMCBHTGACCTKWA Direction: Forward Position #: 1 Overlap #: 20 Alignment: TGRSCKYTGHCCTWBGWSCTKWA VDBHMAGGTCACCCTGACCY--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AgTGCTCCACTGTGgTGTCACAgT Reverse Complement Original Motif TWYAGGTCADVGYGYRYDGBVBD AGTGCTCCACTGTGGTGTCACAGT AGTGCTCCACTKTBVKGTCABAGTGYRYDGBVBD Direction: Forward Position #: 12 Overlap #: 13 Alignment: -----------TWYAGGTCADVGYGYRYDGBVBD AGTGCTCCACTGTGGTGTCACAGT---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AmTGTGACACCACAGT Original Motif Original Motif AGTGCTCCACTKTBVKGTCABAGTGYRYDGBVBD AMTGTGACACCACAGT AVTGYKMCACYRYVGTGTCABAGTGYRYDGBVBD Direction: Forward Position #: 1 Overlap #: 16 Alignment: AGTGCTCCACTKTBVKGTCABAGTGYRYDGBVBD AMTGTGACACCACAGT------------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CagTGCTCCACTGTGgT Combined Motif Reverse Complement Original Motif DBVBCDKKKCACTBTGACACBKKMGTGYRMCAVT CAGTGCTCCACTGTGBT DBVVYGCTBCACTGTGDYACBKKMGTGYRMCAVT Direction: Forward Position #: 2 Overlap #: 17 Alignment: DBVBCDKKKCACTBTGACACBKKMGTGYRMCAVT -CAGTGCTCCACTGTGBT---------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Reverse Complement Reverse Complement AVTGYKMCACYRYVGTKDCACAGTGBAGCMVBBD BAGGYCABHBTGACCKHV AVTGYKMCASBDCAVBBTSACMGTGBAGCMVBBD Direction: Forward Position #: 8 Overlap #: 18 Alignment: AVTGYKMCACYRYVGTKDCACAGTGBAGCMVBBD -------BAGGYCABHBTGACCKHV--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- MIZF Combined Motif Original Motif Reverse Complement AVTGYKMCASBDCAVBBTSACMGTGBAGCMVBBD GCGGACGTTV AVTGYKMCASBDCAVKCKGACVTTVBAGCMVBBD Direction: Forward Position #: 16 Overlap #: 10 Alignment: AVTGYKMCASBDCAVBBTSACMGTGBAGCMVBBD ---------------GCGGACGTTV--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR2F1 Combined Motif Reverse Complement Reverse Complement DBVVYGCTBVAAVGTCYGYVTGDBSTGYRMCAVT AKGYYCAAAGRTCA DBVVHKSTBCAAMGDYCRYVTGDBSTGYRMCAVT Direction: Forward Position #: 5 Overlap #: 14 Alignment: DBVVYGCTBVAAVGTCYGYVTGDBSTGYRMCAVT ----AKGYYCAAAGRTCA---------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TGGAGCACTGTGACAcCACAGTGg Combined Motif Reverse Complement Reverse Complement AVTGYKMCASBDCAVKKGMDCYTTGBASYHVBBD CCACTGTGVTGTCACAGTGCTCCA AVTGYKMCACTGYRVTGKCACWKTGCWCCAVBBD Direction: Forward Position #: 7 Overlap #: 24 Alignment: AVTGYKMCASBDCAVKKGMDCYTTGBASYHVBBD ------CCACTGTGVTGTCACAGTGCTCCA---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 11 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR4A2 NR1H2RXRA Original Motif Original Motif AAGGTCAC AAAGGTCAAAGGTCAAC AGGTCAACAAGGTCAMA Direction: Backward Position #: 9 Overlap #: 8 Alignment: -AAGGTCAC-------- AAAGGTCAAAGGTCAAC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Original Motif Reverse Complement AGGTCAACAAGGTCAMA MGGTCAGGGTGACCTRDBHV AGGTCARSRWGRYCWVVBHV Direction: Forward Position #: 1 Overlap #: 17 Alignment: AGGTCAACAAGGTCAMA--- MGGTCAGGGTGACCTRDBHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Reverse Complement Reverse Complement VDBBBWGKMCWKSKTGACCT BAGGYCABHBTGACCKHV VDBBBWGGHCABBBTGACCTHV Direction: Forward Position #: 5 Overlap #: 16 Alignment: VDBBBWGKMCWKSKTGACCT-- ----BAGGYCABHBTGACCKHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PPARGRXRA Reverse Complement Original Motif VHAGGTCAVBVTGDCCWVVBHV BTRGGDCARAGGKCA VHRGGTCARRGKKBMCWVVBHV Direction: Forward Position #: 1 Overlap #: 15 Alignment: VHAGGTCAVBVTGDCCWVVBHV BTRGGDCARAGGKCA------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACTGTGrYrtCACAGTGswsCAcT Original Motif Original Motif VHRGGTCARRGKKBMCWVVBHV CACTGTGRTRTCACAGTGSWSCACT CACTGTKRKGTCACAGTGSWCCAVTHV Direction: Forward Position #: 6 Overlap #: 20 Alignment: -----VHRGGTCARRGKKBMCWVVBHV CACTGTGRTRTCACAGTGSWSCACT-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR2F1 Combined Motif Reverse Complement Reverse Complement VDAVTGGWSCACTGTGACYKYACAGTG AKGYYCAAAGRTCA VDAVKGBHCMAMKRTSACYKYACAGTG Direction: Forward Position #: 4 Overlap #: 14 Alignment: VDAVTGGWSCACTGTGACYKYACAGTG ---AKGYYCAAAGRTCA---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- REST Combined Motif Original Motif Original Motif VDAVKGBHCMAMKRTSACYKYACAGTG TTCAGCACCATGGACAGCKCC VDHCAGBACCAHGGWCASYKCMCAGTG Direction: Forward Position #: 2 Overlap #: 21 Alignment: VDAVKGBHCMAMKRTSACYKYACAGTG -TTCAGCACCATGGACAGCKCC----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TGGAGCACTGTGACAcCACAGTGg Reverse Complement Reverse Complement CACTGRGYKSTGWCCDTGGTBCTGHDV CCACTGTGVTGTCACAGTGCTCCA CCACTGTGBTGTSACMGTGSTSCWGHDV Direction: Forward Position #: 2 Overlap #: 23 Alignment: -CACTGRGYKSTGWCCDTGGTBCTGHDV CCACTGTGVTGTCACAGTGCTCCA---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AmTGTGACACCACAGT Reverse Complement Original Motif VDHCWGSASCACYGTSACABCACAGTGG AMTGTGACACCACAGT AVTGTKRCACCACAGTSACABCACAGTGG Direction: Forward Position #: 2 Overlap #: 15 Alignment: -VDHCWGSASCACYGTSACABCACAGTGG AMTGTGACACCACAGT------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TgTGgTGTCACAGTGCTCC Combined Motif Original Motif Reverse Complement AVTGTKRCACCACAGTSACABCACAGTGG GGAGCACTGTGACACCACA AVTGTKRSASCACWGTGACABCACAGTGG Direction: Forward Position #: 7 Overlap #: 19 Alignment: AVTGTKRCACCACAGTSACABCACAGTGG ------GGAGCACTGTGACACCACA---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 12 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RORA_1 Esrrb Original Motif Original Motif AWVDAGGTCA VBBYCAAGGTCA DTCAAGGTCAVB Direction: Backward Position #: 1 Overlap #: 10 Alignment: --AWVDAGGTCA VBBYCAAGGTCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Original Motif Original Motif DTCAAGGTCAVB VDBHMAGGTCACCCTGACCY VDBCHAGGTCAVBCTGACCY Direction: Forward Position #: 2 Overlap #: 12 Alignment: -DTCAAGGTCAVB------- VDBHMAGGTCACCCTGACCY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR1H2RXRA Combined Motif Original Motif Reverse Complement VDBCHAGGTCAVBCTGACCY GTTGACCTTTGACCTTT VDBCHAGGTCAVBYTGACCTTTGACCTTT Direction: Forward Position #: 13 Overlap #: 8 Alignment: VDBCHAGGTCAVBCTGACCY--------- ------------GTTGACCTTTGACCTTT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR2F1 Combined Motif Reverse Complement Reverse Complement AAAGGTCAAAGGTCAMBVTGACCTHGVDV AKGYYCAAAGRTCA AARGGTCAAAGGTCAMBVTGACCTHGVDV Direction: Forward Position #: 2 Overlap #: 14 Alignment: AAAGGTCAAAGGTCAMBVTGACCTHGVDV -AKGYYCAAAGRTCA-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PPARGRXRA Original Motif Original Motif AARGGTCAAAGGTCAMBVTGACCTHGVDV BTRGGDCARAGGKCA VDRGGKCAAAGGTCAMBVTGACCTHGVDV Direction: Forward Position #: 1 Overlap #: 15 Alignment: AARGGTCAAAGGTCAMBVTGACCTHGVDV BTRGGDCARAGGKCA-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Original Motif Original Motif VDRGGKCAAAGGTCAMBVTGACCTHGVDV TTCAGCACCATGGACAGCKCC THCAGSACMAHGGWCAGCDYSACCTHGVDV Direction: Forward Position #: 2 Overlap #: 20 Alignment: -VDRGGKCAAAGGTCAMBVTGACCTHGVDV TTCAGCACCATGGACAGCKCC--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- HNF4A Combined Motif Reverse Complement Original Motif VDBCHAGGTSMHGCTGWCCHTYGTSCTGHA RGGBCAAAGKYCA VDBCHAGGKBMARMKGHCMHTYGTSCTGHA Direction: Forward Position #: 7 Overlap #: 13 Alignment: VDBCHAGGTSMHGCTGWCCHTYGTSCTGHA ------RGGBCAAAGKYCA----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TgTGgTGTCACAGTGCTCC Original Motif Original Motif VDBCHAGGKBMARMKGHCMHTYGTSCTGHA TGTGGTGTCACAGTGCTCC ACAGTGCTCCWRHGGTSYCVDBCHAGGKBMARMKGHCMHT Direction: Backward Position #: 11 Overlap #: 9 Alignment: VDBCHAGGKBMARMKGHCMHTYGTSCTGHA---------- ---------------------TGTGGTGTCACAGTGCTCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wwCCAmAGTCmt Combined Motif Reverse Complement Reverse Complement AHRGHCRYKTRBRCCTHGVDVGMSACCHMWGGAGCACTGT VDGACTRTGGDD AHDGACDDTKGBDCCTHGVDVGMSACCHMWGGAGCACTGT Direction: Forward Position #: 2 Overlap #: 12 Alignment: AHRGHCRYKTRBRCCTHGVDVGMSACCHMWGGAGCACTGT -VDGACTRTGGDD--------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Reverse Complement Reverse Complement ACAGTGCTCCWRHGGTSYCVDBCHAGGDVCYAHDGTCHHT BAGGYCABHBTGACCKHV ACAGWGSTCMHVHTGWCYBDDBCHAGGDVCYAHDGTCHHT Direction: Forward Position #: 4 Overlap #: 18 Alignment: ACAGTGCTCCWRHGGTSYCVDBCHAGGDVCYAHDGTCHHT ---BAGGYCABHBTGACCKHV------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 13 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- MIZF ESR2 Reverse Complement Reverse Complement GCGGACGTTV BAGGYCABHBTGACCKHV BCKGACSTWVBAGGYCAB Direction: Backward Position #: 1 Overlap #: 10 Alignment: --------GCGGACGTTV BAGGYCABHBTGACCKHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Reverse Complement Reverse Complement BTGMCCTBVWASGTCRGB MGGTCAGGGTGACCTRDBHV MGGTCAGGGTKRCCYDBVHASGTCRGB Direction: Forward Position #: 10 Overlap #: 11 Alignment: ---------BTGMCCTBVWASGTCRGB MGGTCAGGGTGACCTRDBHV------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR1H2RXRA Combined Motif Original Motif Original Motif MGGTCAGGGTKRCCYDBVHASGTCRGB AAAGGTCAAAGGTCAAC MGGTCAGGGTKRCCYDBVAAGGTCARAGGTCAAC Direction: Forward Position #: 18 Overlap #: 10 Alignment: MGGTCAGGGTKRCCYDBVHASGTCRGB------- -----------------AAAGGTCAAAGGTCAAC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 14 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA NR1H2RXRA Original Motif Original Motif BTRGGDCARAGGKCA AAAGGTCAAAGGTCAAC ACVDRGGTCAAAGGTCA Direction: Backward Position #: 3 Overlap #: 15 Alignment: BTRGGDCARAGGKCA-- AAAGGTCAAAGGTCAAC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR2 Reverse Complement Reverse Complement TGACCTTTGACCKDBGT BAGGYCABHBTGACCKHV BAGKBMMCTBTGACCKDBGT Direction: Forward Position #: 4 Overlap #: 15 Alignment: ---TGACCTTTGACCKDBGT BAGGYCABHBTGACCKHV-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Reverse Complement Reverse Complement ACBDRGGTCAVAGRYBRCTB MGGTCAGGGTGACCTRDBHV ACBDAGGTCAVVGDBVVCTVDBHV Direction: Forward Position #: 5 Overlap #: 16 Alignment: ACBDRGGTCAVAGRYBRCTB---- ----MGGTCAGGGTGACCTRDBHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACTGTGrYrtCACAGTGswsCAcT Original Motif Reverse Complement ACBDAGGTCAVVGDBVVCTVDBHV AGTGSWSCACTGTGAMAMCACAGTG AGTGSWSCACTGTGAMACCAMRGTSAVVGDBVVCTVDBHV Direction: Forward Position #: 17 Overlap #: 9 Alignment: ----------------ACBDAGGTCAVVGDBVVCTVDBHV AGTGSWSCACTGTGAMAMCACAGTG--------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Original Motif Reverse Complement AGTGSWSCACTGTGAMACCAMRGTSAVVGDBVVCTVDBHV BMSMGCCYMCTKSTGGMHM BAGYGCMBCMYTGTGRMMMCAMRGTSAVVGDBVVCTVDBHV Direction: Forward Position #: 2 Overlap #: 18 Alignment: -AGTGSWSCACTGTGAMACCAMRGTSAVVGDBVVCTVDBHV BMSMGCCYMCTKSTGGMHM---------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Original Motif Original Motif BAGYGCMBCMYTGTGRMMMCAMRGTSAVVGDBVVCTVDBHV TTCAGCACCATGGACAGCKCC BHSAGCACCMYKGWSASMVCMMRGTSAVVGDBVVCTVDBHV Direction: Forward Position #: 1 Overlap #: 21 Alignment: BAGYGCMBCMYTGTGRMMMCAMRGTSAVVGDBVVCTVDBHV TTCAGCACCATGGACAGCKCC-------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TGGAGCACTGTGACAcCACAGTGg Combined Motif Original Motif Reverse Complement BHSAGCACCMYKGWSASMVCMMRGTSAVVGDBVVCTVDBHV CCACTGTGVTGTCACAGTGCTCCA BHSAGCACCAYTGTGRKVTCACAGTGMDVSABVVCTVDBHV Direction: Forward Position #: 8 Overlap #: 24 Alignment: BHSAGCACCMYKGWSASMVCMMRGTSAVVGDBVVCTVDBHV -------CCACTGTGVTGTCACAGTGCTCCA---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TgTGgTGTCACAGTGCTCC Original Motif Original Motif BHSAGCACCAYTGTGRKVTCACAGTGMDVSABVVCTVDBHV TGTGGTGTCACAGTGCTCC TDYDGYRYCACWGTGVTSYCACAGTGMDVSABVVCTVDBHV Direction: Forward Position #: 1 Overlap #: 19 Alignment: BHSAGCACCAYTGTGRKVTCACAGTGMDVSABVVCTVDBHV TGTGGTGTCACAGTGCTCC---------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NR2F1 Reverse Complement Original Motif VDBHVAGVBBTSVDYCACTGTGKSAVCACWGTGMMMCHMHA TGAMCTTTGMMCYT TGAVCYYWGVHCHBVDYCACTGTGKSAVCACWGTGMMMCHMHA Direction: Forward Position #: 3 Overlap #: 12 Alignment: --VDBHVAGVBBTSVDYCACTGTGKSAVCACWGTGMMMCHMHA TGAMCTTTGMMCYT----------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Tcfcp2l1 Reverse Complement Reverse Complement TDYDGYRYCACWGTGVTSYCACAGTGMDVBHGDBCWMMGVTCA CKGGDTBDMMCTGG YDKGGTDBMACWGKGVTSYCACAGTGMDVBHGDBCWMMGVTCA Direction: Forward Position #: 1 Overlap #: 14 Alignment: TDYDGYRYCACWGTGVTSYCACAGTGMDVBHGDBCWMMGVTCA CKGGDTBDMMCTGG----------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 15 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Tcfcp2l1 ESR1 Original Motif Reverse Complement CCAGYYHVADCCRG MGGTCAGGGTGACCTRDBHV MGGYCAGBBTGAVCYRGBHV Direction: Forward Position #: 4 Overlap #: 14 Alignment: ---CCAGYYHVADCCRG--- MGGTCAGGGTGACCTRDBHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CTCF Combined Motif Reverse Complement Original Motif VDBCKKGVTCAVVCTGKCCY YDRCCASYAGRKGGCRSYV VDBYDDSCWCHAGVKGGCVBYV Direction: Forward Position #: 4 Overlap #: 17 Alignment: VDBCKKGVTCAVVCTGKCCY-- ---YDRCCASYAGRKGGCRSYV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Original Motif Reverse Complement VDBYDDSCWCHAGVKGGCVBYV BAGGYCABHBTGACCKHV VDBYBDGSHCAHVVTGRCCBHV Direction: Forward Position #: 5 Overlap #: 18 Alignment: VDBYDDSCWCHAGVKGGCVBYV ----BAGGYCABHBTGACCKHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PPARGRXRA Reverse Complement Original Motif VHVGGKCAVVHTGHSCDBKBHV BTRGGDCARAGGKCA VHRGGKCAVVGKKHVCDBKBHV Direction: Forward Position #: 1 Overlap #: 15 Alignment: VHVGGKCAVVHTGHSCDBKBHV BTRGGDCARAGGKCA------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CagTGCTCCACTGTGgT Combined Motif Reverse Complement Original Motif VDBYBDGBDYYCBBTGYCCKHV CAGTGCTCCACTGTGBT VDBYBDGBDYYCHBTGCYCCACTGTGBT Direction: Forward Position #: 12 Overlap #: 11 Alignment: VDBYBDGBDYYCBBTGYCCKHV------ -----------CAGTGCTCCACTGTGBT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACTGTGrYrtCACAGTGswsCAcT Original Motif Original Motif VDBYBDGBDYYCHBTGCYCCACTGTGBT CACTGTGRTRTCACAGTGSWSCACT CACTGTGVBDBCACAGTGCTCCACTGTGBT Direction: Forward Position #: 3 Overlap #: 23 Alignment: --VDBYBDGBDYYCHBTGCYCCACTGTGBT CACTGTGRTRTCACAGTGSWSCACT----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Reverse Complement Original Motif ABCACAGTGGAGCACTGTGVHVBCACAGTG TTCAGCACCATGGACAGCKCC TTCAGCACMDTGGASMRCDSYGVHVBCACAGTG Direction: Forward Position #: 4 Overlap #: 18 Alignment: ---ABCACAGTGGAGCACTGTGVHVBCACAGTG TTCAGCACCATGGACAGCKCC------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif HNF4A Reverse Complement Reverse Complement CACTGTGVBDBCKSDGMYSTCCAHRGTGCTGAA TGMYCTTTGBCCK YRMYSTKTGBHCKSDGMYSTCCAHRGTGCTGAA Direction: Forward Position #: 1 Overlap #: 13 Alignment: CACTGTGVBDBCKSDGMYSTCCAHRGTGCTGAA TGMYCTTTGBCCK-------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CAcCACAGTGGAGCAct Reverse Complement Reverse Complement TTCAGCACMDTGGASMRCDSYGDBCARASMRKK AGTGCTCCACTGTGDTG AGTKCWSCACWGTGGWGMRCDSYGDBCARASMRKK Direction: Forward Position #: 3 Overlap #: 15 Alignment: --TTCAGCACMDTGGASMRCDSYGDBCARASMRKK AGTGCTCCACTGTGDTG------------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR2F1 Combined Motif Reverse Complement Original Motif YRMYSTKTGBHCKSDGMYCWCCACWGTGSWGYACT TGAMCTTTGMMCYT YRMYSTKTGAMCTYTGMHCHYCACWGTGSWGYACT Direction: Forward Position #: 8 Overlap #: 14 Alignment: YRMYSTKTGBHCKSDGMYCWCCACWGTGSWGYACT -------TGAMCTTTGMMCYT-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 16 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CTCF ESR1 Original Motif Reverse Complement YDRCCASYAGRKGGCRSYV MGGTCAGGGTGACCTRDBHV MBGDCMRSBWGRBSKVRSHV Direction: Forward Position #: 2 Overlap #: 19 Alignment: -YDRCCASYAGRKGGCRSYV MGGTCAGGGTGACCTRDBHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AgTGCTCCACTGTGgTGTCACAgT Original Motif Original Motif MBGDCMRSBWGRBSKVRSHV AGTGCTCCACTGTGGTGTCACAGT AGTGCTCCACTGTGVTGTCAVVBTGRBSKVRSHV Direction: Forward Position #: 15 Overlap #: 10 Alignment: --------------MBGDCMRSBWGRBSKVRSHV AGTGCTCCACTGTGGTGTCACAGT---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CACTGTGrYrtCACAGTGswsCAcT Combined Motif Original Motif Original Motif AGTGCTCCACTGTGVTGTCAVVBTGRBSKVRSHV CACTGTGRTRTCACAGTGSWSCACT AGTGCTCCACTGTGVTGTCACAGTGVHSBAVBHV Direction: Forward Position #: 8 Overlap #: 25 Alignment: AGTGCTCCACTGTGVTGTCAVVBTGRBSKVRSHV -------CACTGTGRTRTCACAGTGSWSCACT-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CagTGCTCCACTGTGgT Original Motif Original Motif AGTGCTCCACTGTGVTGTCACAGTGVHSBAVBHV CAGTGCTCCACTGTGBT CAGTGCTCCACTGTGVTGTCACAGTGVHSBAVBHV Direction: Forward Position #: 2 Overlap #: 16 Alignment: -AGTGCTCCACTGTGVTGTCACAGTGVHSBAVBHV CAGTGCTCCACTGTGBT------------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CAcCACAGTGGAGCAct Combined Motif Reverse Complement Original Motif BDVVTBSHVCACTGTGACAVCACAGTGGAGCACTG CAHCACAGTGGAGCACT BDVVTBCAVCACWGTGRMRCMMYAGTGGAGCACTG Direction: Forward Position #: 7 Overlap #: 17 Alignment: BDVVTBSHVCACTGTGACAVCACAGTGGAGCACTG ------CAHCACAGTGGAGCACT------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TGGAGCACTGTGACAcCACAGTGg Original Motif Reverse Complement BDVVTBCAVCACWGTGRMRCMMYAGTGGAGCACTG CCACTGTGVTGTCACAGTGCTCCA CCACTRTKBYRTCACAGTGVWVCAMYAGTGGAGCACTG Direction: Forward Position #: 4 Overlap #: 21 Alignment: ---BDVVTBCAVCACWGTGRMRCMMYAGTGGAGCACTG CCACTGTGVTGTCACAGTGCTCCA-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Tcfcp2l1 Combined Motif Reverse Complement Original Motif CAGTGCTCCACTKYTGVWVCACTGTGAMMBYAMAGTGG CCAGYYHVADCCRG CAGTGCTCCMMKBYYDVDCCASTGTGAMMBYAMAGTGG Direction: Forward Position #: 9 Overlap #: 14 Alignment: CAGTGCTCCACTKYTGVWVCACTGTGAMMBYAMAGTGG --------CCAGYYHVADCCRG---------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR2 Original Motif Reverse Complement CAGTGCTCCMMKBYYDVDCCASTGTGAMMBYAMAGTGG BAGGYCABHBTGACCKHV CAGKBCWCCVTGDCYKDDCCASTGTGAMMBYAMAGTGG Direction: Forward Position #: 1 Overlap #: 18 Alignment: CAGTGCTCCMMKBYYDVDCCASTGTGAMMBYAMAGTGG BAGGYCABHBTGACCKHV-------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Reverse Complement Original Motif CCACTRTKBYRTCACASTGGDDYKGDCAVGGWGBRCTG BTRGGDCARAGGKCA CCACTRBBDKGBCAMAGKKSADYKGDCAVGGWGBRCTG Direction: Forward Position #: 7 Overlap #: 15 Alignment: CCACTRTKBYRTCACASTGGDDYKGDCAVGGWGBRCTG ------BTRGGDCARAGGKCA----------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCCCCGCSssk Combined Motif Reverse Complement Reverse Complement CAGKBCWCCVTGDCYKDTSYYCTRTGVCYHVVMAGTGG BBSGGCGGGGBS CAGKBCWCCVBGGCSGGKSBYCTRTGVCYHVVMAGTGG Direction: Forward Position #: 9 Overlap #: 12 Alignment: CAGKBCWCCVTGDCYKDTSYYCTRTGVCYHVVMAGTGG --------BBSGGCGGGGBS------------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 17 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TgTGgTGTCACAGTGCTCC TGGAGCACTGTGACAcCACAGTGg Reverse Complement Original Motif GGAGCACTGTGACACCACA TGGAGCACTGTGACAVCACAGTGG GTGGGGAGCACTGTGACACCACAT Direction: Backward Position #: 5 Overlap #: 19 Alignment: -GGAGCACTGTGACACCACA---- TGGAGCACTGTGACAVCACAGTGG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACTGTGrYrtCACAGTGswsCAcT Reverse Complement Original Motif ATGTGGTGTCACAGTGCTCCCCAC CACTGTGRTRTCACAGTGSWSCACT CAMTGTGVTGTCACAGTGCTCCMCWC Direction: Forward Position #: 3 Overlap #: 23 Alignment: --ATGTGGTGTCACAGTGCTCCCCAC CACTGTGRTRTCACAGTGSWSCACT- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- AgTGCTCCACTGTGgTGTCACAgT Combined Motif Original Motif Reverse Complement CAMTGTGVTGTCACAGTGCTCCMCWC ACTGTGACACCACAGTGGAGCACT CAMTGTGAYRYCACAGTGSWSCACWC Direction: Forward Position #: 2 Overlap #: 24 Alignment: CAMTGTGVTGTCACAGTGCTCCMCWC -ACTGTGACACCACAGTGGAGCACT- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Reverse Complement Original Motif GWGTGSWSCACTGTGMKKTCACARTG VDBHMAGGTCACCCTGACCY VGHVYRSKBCACYSTGMYBTCACARTG Direction: Forward Position #: 2 Overlap #: 19 Alignment: -GWGTGSWSCACTGTGMKKTCACARTG VDBHMAGGTCACCCTGACCY------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Reverse Complement Original Motif CAMTGTGABKYCASMGTGVYSMMVHCV VHRGGTCABDBTGMCCTB CAMTGTDRGGTCABVGTGVCCYVVHCV Direction: Forward Position #: 6 Overlap #: 18 Alignment: CAMTGTGABKYCASMGTGVYSMMVHCV -----VHRGGTCABDBTGMCCTB---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CagTGCTCCACTGTGgT Reverse Complement Reverse Complement VGHVVMGGBCACBBTGACCKHACARTG ABCACAGTGGAGCACTG ABCASAGTVGRGCACTGTGACCKHACARTG Direction: Forward Position #: 4 Overlap #: 14 Alignment: ---VGHVVMGGBCACBBTGACCKHACARTG ABCACAGTGGAGCACTG------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AmTGTGACACCACAGT Reverse Complement Reverse Complement CAMTGTDRGGTCACAGTGCKCVACTSTGBT ACTGTGGTGTCACART ACWVTGBTRKSWCAVHGTGCKCVACTSTGBT Direction: Forward Position #: 2 Overlap #: 15 Alignment: -CAMTGTDRGGTCACAGTGCKCVACTSTGBT ACTGTGGTGTCACART--------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Reverse Complement Original Motif ABCASAGTVGRGCACHVTGWSRMABCAVWGT BTRGGDCARAGGKCA ABCRGRGBARAGSDCAVTGWSRMABCAVWGT Direction: Forward Position #: 2 Overlap #: 15 Alignment: ABCASAGTVGRGCACHVTGWSRMABCAVWGT -BTRGGDCARAGGKCA--------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CAcCACAGTGGAGCAct Original Motif Original Motif ABCRGRGBARAGSDCAVTGWSRMABCAVWGT CAHCACAGTGGAGCACT CABCACAGTGGAGCACWVTGWSRMABCAVWGT Direction: Forward Position #: 2 Overlap #: 16 Alignment: -ABCRGRGBARAGSDCAVTGWSRMABCAVWGT CAHCACAGTGGAGCACT--------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Esrrb Reverse Complement Reverse Complement ACWVTGBTRKSWCAVWGTGCTCCACTGTGBTG TGACCTTGMBBB TGACYTTGVBVBSWCAVWGTGCTCCACTGTGBTG Direction: Forward Position #: 3 Overlap #: 10 Alignment: --ACWVTGBTRKSWCAVWGTGCTCCACTGTGBTG TGACCTTGMBBB---------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 18 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- sscCCCGCGcs ssCCCCGCSssk Original Motif Original Motif BSCCCCGCGBS SBCCCCGCCSBB SSCCCCGCSSSB Direction: Forward Position #: 1 Overlap #: 11 Alignment: BSCCCCGCGBS- SBCCCCGCCSBB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- gCGCGCsCgsG Combined Motif Original Motif Original Motif SSCCCCGCSSSB GCGCGCSCGCG SSSCSCGCSCSSG Direction: Forward Position #: 3 Overlap #: 10 Alignment: SSCCCCGCSSSB- --GCGCGCSCGCG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssGCkTGCssk Combined Motif Reverse Complement Reverse Complement CSSGSGCGSGSSS YSSGCAYGCSS CSYSSGCRCGCSS Direction: Forward Position #: 3 Overlap #: 11 Alignment: CSSGSGCGSGSSS --YSSGCAYGCSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CTCF Combined Motif Original Motif Original Motif CSYSSGCRCGCSS YDRCCASYAGRKGGCRSYV CSYGSSCASBMGGKGGCRSYV Direction: Forward Position #: 3 Overlap #: 11 Alignment: CSYSSGCRCGCSS-------- --YDRCCASYAGRKGGCRSYV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Reverse Complement Reverse Complement BMSMGCCYCCYBSTGSSCKSG MGGTCAGGGTGACCTRDBHV BMSMRSSYCMBBGTGVCCKVGBHV Direction: Forward Position #: 5 Overlap #: 17 Alignment: BMSMGCCYCCYBSTGSSCKSG--- ----MGGTCAGGGTGACCTRDBHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- cCGCGGrCACG Combined Motif Reverse Complement Original Motif VDBCVRGGBCACBBYGMSSMRSYV CCGCGGRCACG VDBCGCGGDCACGBYGMSSMRSYV Direction: Forward Position #: 3 Overlap #: 11 Alignment: VDBCVRGGBCACBBYGMSSMRSYV --CCGCGGRCACG----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Reverse Complement Original Motif BMSMRSSYCMBCGTGHCCGCGBHV TTCAGCACCATGGACAGCKCC BHCAGSMCCMBGGWSASCDCBBHV Direction: Forward Position #: 1 Overlap #: 21 Alignment: BMSMRSSYCMBCGTGHCCGCGBHV TTCAGCACCATGGACAGCKCC--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Myc Combined Motif Reverse Complement Reverse Complement VDBBGHGSTSWCCVYGGYSCTGHV DCCACGTGCV VDCCVCGYKSDCCVYGGYSCTGHV Direction: Forward Position #: 2 Overlap #: 10 Alignment: VDBBGHGSTSWCCVYGGYSCTGHV -DCCACGTGCV------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mycn Combined Motif Original Motif Reverse Complement VDCCVCGYKSDCCVYGGYSCTGHV GCCACGTGSD VGCCACGTGSDCCVYGGYSCTGHV Direction: Forward Position #: 2 Overlap #: 10 Alignment: VDCCVCGYKSDCCVYGGYSCTGHV -GCCACGTGSD------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- srACyCCGAyr Combined Motif Original Motif Reverse Complement VGCCACGTGSDCCVYGGYSCTGHV KKTCGGKGTKS CTGHVKBTCGGKGKKSVGCCACGT Direction: Backward Position #: 6 Overlap #: 11 Alignment: VGCCACGTGSDCCVYGGYSCTGHV --------KKTCGGKGTKS----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 19 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- atactttggc wwCCAmAGTCmt Reverse Complement Original Motif GCCAAAGTAT DDCCAMAGTCHB DGCCAAAGTMTB Direction: Forward Position #: 2 Overlap #: 10 Alignment: -GCCAAAGTAT- DDCCAMAGTCHB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- taaacgatgcc Combined Motif Reverse Complement Reverse Complement VAYACTTTGGCD GGCATCGTTTA VAYACTTTGGCATCGTTTA Direction: Forward Position #: 9 Overlap #: 4 Alignment: VAYACTTTGGCD------- --------GGCATCGTTTA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR1H2RXRA Combined Motif Reverse Complement Reverse Complement TAAACGATGCCAAAGTMTB GTTGACCTTTGACCTTT GCCAAAGTMTBTRAMCKWTTAAACGATGCC Direction: Backward Position #: 12 Overlap #: 8 Alignment: ---------TAAACGATGCCAAAGTMTB -----------GTTGACCTTTGACCTTT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 20 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CagTGCTCCACTGTGgT CTCF Original Motif Reverse Complement CAGTGCTCCACTGTGBT BMSMGCCYMCTKSTGGMHM SMGYSCYCYACTGKGBHBM Direction: Backward Position #: 1 Overlap #: 17 Alignment: --CAGTGCTCCACTGTGBT BMSMGCCYMCTKSTGGMHM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Original Motif Reverse Complement SMGYSCYCYACTGKGBHBM GGYGCTGTCCATGGTGCTGAA GSMGCTSTCCABKGTGCTGAA Direction: Forward Position #: 2 Overlap #: 19 Alignment: -SMGYSCYCYACTGKGBHBM- GGYGCTGTCCATGGTGCTGAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TgTGgTGTCACAGTGCTCC Combined Motif Reverse Complement Reverse Complement TTCAGCACYBTGGASAGCRSC GGAGCACTGTGACACCACA TTCAGCACYBTGGAGMRCWGYGACACCACA Direction: Forward Position #: 12 Overlap #: 10 Alignment: TTCAGCACYBTGGASAGCRSC--------- -----------GGAGCACTGTGACACCACA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AgTGCTCCACTGTGgTGTCACAgT Reverse Complement Reverse Complement TGTGGTGTCMCWGKRCTCCABKGTGCTGAA ACTGTGACACCACAGTGGAGCACT ACTGTGRYRYCACAGTGSWSCACTGTGCTGAA Direction: Forward Position #: 3 Overlap #: 22 Alignment: --TGTGGTGTCMCWGKRCTCCABKGTGCTGAA ACTGTGACACCACAGTGGAGCACT-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CACTGTGrYrtCACAGTGswsCAcT Combined Motif Original Motif Reverse Complement ACTGTGRYRYCACAGTGSWSCACTGTGCTGAA AGTGSWSCACTGTGAMAMCACAGTG ACWGTGVWGCMMYRKKRVAVCACWGTGCTGAA Direction: Forward Position #: 3 Overlap #: 25 Alignment: ACTGTGRYRYCACAGTGSWSCACTGTGCTGAA --AGTGSWSCACTGTGAMAMCACAGTG----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TGGAGCACTGTGACAcCACAGTGg Reverse Complement Original Motif TTCAGCACWGTGVTVKYRMMRYGCWVCACWGT TGGAGCACTGTGACAVCACAGTGG TKSAGCACTGTGAYABCACAGTGVWVCACWGT Direction: Forward Position #: 1 Overlap #: 24 Alignment: TTCAGCACWGTGVTVKYRMMRYGCWVCACWGT TGGAGCACTGTGACAVCACAGTGG-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CAcCACAGTGGAGCAct Original Motif Reverse Complement TKSAGCACTGTGAYABCACAGTGVWVCACWGT AGTGCTCCACTGTGDTG AGTGCWSCACTGTGVTRBCACAGTGVWVCACWGT Direction: Forward Position #: 3 Overlap #: 15 Alignment: --TKSAGCACTGTGAYABCACAGTGVWVCACWGT AGTGCTCCACTGTGDTG----------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AmTGTGACACCACAGT Reverse Complement Reverse Complement ACWGTGVWVCACTGTGBMABCACAGTGSWGCACT ACTGTGGTGTCACART ACTGTGGTGYMMYRKKBMABCACAGTGSWGCACT Direction: Forward Position #: 1 Overlap #: 16 Alignment: ACWGTGVWVCACTGTGBMABCACAGTGSWGCACT ACTGTGGTGTCACART------------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Tcfcp2l1 Reverse Complement Reverse Complement AGTGCWSCACTGTGVTRBRRKKYRMCACCACAGT CKGGDTBDMMCTGG CDGKKBDBMACTGKGVTRBRRKKYRMCACCACAGT Direction: Forward Position #: 2 Overlap #: 13 Alignment: -AGTGCWSCACTGTGVTRBRRKKYRMCACCACAGT CKGGDTBDMMCTGG--------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wwCCAmAGTCmt Combined Motif Original Motif Original Motif CDGKKBDBMACTGKGVTRBRRKKYRMCACCACAGT DDCCAMAGTCHB CDGKKDDCCACWGTSVHRBRRKKYRMCACCACAGT Direction: Forward Position #: 6 Overlap #: 12 Alignment: CDGKKBDBMACTGKGVTRBRRKKYRMCACCACAGT -----DDCCAMAGTCHB------------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 21 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- AmTGTGACACCACAGT AgTGCTCCACTGTGgTGTCACAgT Original Motif Reverse Complement AMTGTGACACCACAGT ACTGTGACACCACAGTGGAGCACT ACTGTGACACCACAGTGGAGCACT Direction: Forward Position #: 1 Overlap #: 16 Alignment: AMTGTGACACCACAGT-------- ACTGTGACACCACAGTGGAGCACT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TGGAGCACTGTGACAcCACAGTGg Original Motif Reverse Complement ACTGTGACACCACAGTGGAGCACT CCACTGTGVTGTCACAGTGCTCCA CCACTGTGAYRYCACAGTGSWSCACT Direction: Forward Position #: 3 Overlap #: 22 Alignment: --ACTGTGACACCACAGTGGAGCACT CCACTGTGVTGTCACAGTGCTCCA-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CACTGTGrYrtCACAGTGswsCAcT Combined Motif Original Motif Original Motif CCACTGTGAYRYCACAGTGSWSCACT CACTGTGRTRTCACAGTGSWSCACT CCACTGTGRYRTCACAGTGSWSCACT Direction: Forward Position #: 2 Overlap #: 25 Alignment: CCACTGTGAYRYCACAGTGSWSCACT -CACTGTGRTRTCACAGTGSWSCACT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TgTGgTGTCACAGTGCTCC Reverse Complement Original Motif AGTGSWSCACTGTGAMMKCACAGTGG TGTGGTGTCACAGTGCTCC TRKKGYDKCACWGTGMHMBCACAGTGG Direction: Forward Position #: 2 Overlap #: 18 Alignment: -AGTGSWSCACTGTGAMMKCACAGTGG TGTGGTGTCACAGTGCTCC-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CagTGCTCCACTGTGgT Original Motif Original Motif TRKKGYDKCACWGTGMHMBCACAGTGG CAGTGCTCCACTGTGBT YAKTGCTYCACTGTGVTMBCACAGTGG Direction: Forward Position #: 1 Overlap #: 17 Alignment: TRKKGYDKCACWGTGMHMBCACAGTGG CAGTGCTCCACTGTGBT---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CAcCACAGTGGAGCAct Reverse Complement Original Motif CCACTGTGBRAVCACAGTGKAGCAYTM CAHCACAGTGGAGCACT CACCACWGTGGARCMMYAGTGKAGCAYTM Direction: Forward Position #: 3 Overlap #: 15 Alignment: --CCACTGTGBRAVCACAGTGKAGCAYTM CAHCACAGTGGAGCACT------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Reverse Complement Original Motif YAKTGCTYCACTKYRGMTCCACWGTGGTG VDBHMAGGTCACCCTGACCY VBVBBRSKYCACHBTGVCYYCACWGTGGTG Direction: Forward Position #: 2 Overlap #: 19 Alignment: -YAKTGCTYCACTKYRGMTCCACWGTGGTG VDBHMAGGTCACCCTGACCY---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Original Motif Reverse Complement VBVBBRSKYCACHBTGVCYYCACWGTGGTG GGYGCTGTCCATGGTGCTGAA AASRCBCTGDCCHYRSTGYKGVBVBBRSKYCA Direction: Backward Position #: 3 Overlap #: 19 Alignment: VBVBBRSKYCACHBTGVCYYCACWGTGGTG-- -----------GGYGCTGTCCATGGTGCTGAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 22 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CACTGTGrYrtCACAGTGswsCAcT AgTGCTCCACTGTGgTGTCACAgT Original Motif Reverse Complement CACTGTGRTRTCACAGTGSWSCACT ACTGTGACACCACAGTGGAGCACT ACTGTGAYAYCACAGTGSAGCACTC Direction: Backward Position #: 1 Overlap #: 24 Alignment: CACTGTGRTRTCACAGTGSWSCACT -ACTGTGACACCACAGTGGAGCACT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TGGAGCACTGTGACAcCACAGTGg Original Motif Reverse Complement ACTGTGAYAYCACAGTGSAGCACTC CCACTGTGVTGTCACAGTGCTCCA CCACTGTGRTRTCACAGTGSWSCACTC Direction: Forward Position #: 3 Overlap #: 22 Alignment: --ACTGTGAYAYCACAGTGSAGCACTC CCACTGTGVTGTCACAGTGCTCCA--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Reverse Complement Original Motif GAGTGSWSCACTGTGAMAKCACAGTGG VDBHMAGGTCACCCTGACCY VGVVYRGRBCACYSTGACMBCACAGTGG Direction: Forward Position #: 2 Overlap #: 19 Alignment: -GAGTGSWSCACTGTGAMAKCACAGTGG VDBHMAGGTCACCCTGACCY-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Reverse Complement Original Motif CCACTGTGVRGTCASMGTGBMCMMVBCV YDRCCASYAGRKGGCRSYV YDVCMMYBWGRGGKCASHVTGBMCMMVBCV Direction: Forward Position #: 3 Overlap #: 17 Alignment: --CCACTGTGVRGTCASMGTGBMCMMVBCV YDRCCASYAGRKGGCRSYV----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TgTGgTGTCACAGTGCTCC Original Motif Reverse Complement YDVCMMYBWGRGGKCASHVTGBMCMMVBCV GGAGCACTGTGACACCACA GBAGCACTGTGABRBCACAVTGBMCMMVBCV Direction: Forward Position #: 2 Overlap #: 18 Alignment: -YDVCMMYBWGRGGKCASHVTGBMCMMVBCV GGAGCACTGTGACACCACA------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CAcCACAGTGGAGCAct Original Motif Reverse Complement GBAGCACTGTGABRBCACAVTGBMCMMVBCV AGTGCTCCACTGTGDTG AGTGCWSCACTGTGRBRBCACAVTGBMCMMVBCV Direction: Forward Position #: 4 Overlap #: 14 Alignment: ---GBAGCACTGTGABRBCACAVTGBMCMMVBCV AGTGCTCCACTGTGDTG----------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CagTGCTCCACTGTGgT Original Motif Original Motif AGTGCWSCACTGTGRBRBCACAVTGBMCMMVBCV CAGTGCTCCACTGTGBT CAGTGCTCCACTGTGDTRBCACAVTGBMCMMVBCV Direction: Forward Position #: 2 Overlap #: 16 Alignment: -AGTGCWSCACTGTGRBRBCACAVTGBMCMMVBCV CAGTGCTCCACTGTGBT------------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR2 Reverse Complement Reverse Complement VGVVYRGRBCAVTGTGBMAHCACAGTGGAGCACTG BAGGYCABHBTGACCKHV BAGGHCWVBDTSACYKTGBMAHCACAGTGGAGCACTG Direction: Forward Position #: 3 Overlap #: 16 Alignment: --VGVVYRGRBCAVTGTGBMAHCACAGTGGAGCACTG BAGGYCABHBTGACCKHV------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AmTGTGACACCACAGT Reverse Complement Original Motif CAGTGCTCCACTGTGDTRBCAYKGTSAHBVWGHCCTB AMTGTGACACCACAGT AMYRKKRCWCCACWGTGDTRBCAYKGTSAHBVWGHCCTB Direction: Forward Position #: 3 Overlap #: 14 Alignment: --CAGTGCTCCACTGTGDTRBCAYKGTSAHBVWGHCCTB AMTGTGACACCACAGT----------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Reverse Complement Original Motif BAGGHCWVBDTSACYKTGBMAHCACWGTGGWGKYRMMRT TTCAGCACCATGGACAGCKCC TBMRGHACCVBKGACAGHGBCAHCACWGTGGWGKYRMMRT Direction: Forward Position #: 2 Overlap #: 20 Alignment: -BAGGHCWVBDTSACYKTGBMAHCACWGTGGWGKYRMMRT TTCAGCACCATGGACAGCKCC------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 23 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TGGAGCACTGTGACAcCACAGTGg CACTGTGrYrtCACAGTGswsCAcT Original Motif Reverse Complement TGGAGCACTGTGACAVCACAGTGG AGTGSWSCACTGTGAMAMCACAGTG GGAG Direction: Backward Position #: 3 Overlap #: 23 Alignment: ---TGGAGCACTGTGACAVCACAGTGG-------------------------- --AGTGSWSCACTGTGAMAMCACAGTG-------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AgTGCTCCACTGTGgTGTCACAgT Original Motif Original Motif GGAG AGTGCTCCACTGTGGTGTCACAGT RGWGCTCCACTGTGGTGTCACAGT Direction: Forward Position #: 1 Overlap #: 4 Alignment: GGAG-------------------- AGTGCTCCACTGTGGTGTCACAGT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Original Motif Original Motif RGWGCTCCACTGTGGTGTCACAGT VHRGGTCABDBTGMCCTB RGWGCTCCACTGTGRKGTCACABTGMCCTB Direction: Forward Position #: 13 Overlap #: 12 Alignment: RGWGCTCCACTGTGGTGTCACAGT------ ------------VHRGGTCABDBTGMCCTB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Reverse Complement Reverse Complement BAGGYCABTGTGACRMCACAGTGGAGCWCM MGGTCAGGGTGACCTRDBHV BAGGTCABKGTGACVHVVCAGTGGAGCWCM Direction: Forward Position #: 2 Overlap #: 20 Alignment: BAGGYCABTGTGACRMCACAGTGGAGCWCM -MGGTCAGGGTGACCTRDBHV--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TgTGgTGTCACAGTGCTCC Combined Motif Reverse Complement Reverse Complement RGWGCTCCACTGBVHVGTCACYBTGACCTB GGAGCACTGTGACACCACA RGWGSWSCACTGTGACRYCACHBTGACCTB Direction: Forward Position #: 4 Overlap #: 19 Alignment: RGWGCTCCACTGBVHVGTCACYBTGACCTB ---GGAGCACTGTGACACCACA-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CagTGCTCCACTGTGgT Combined Motif Original Motif Reverse Complement RGWGSWSCACTGTGACRYCACHBTGACCTB ABCACAGTGGAGCACTG RGWGSABCACWGTGRMGCMMYDBTGACCTB Direction: Forward Position #: 6 Overlap #: 17 Alignment: RGWGSWSCACTGTGACRYCACHBTGACCTB -----ABCACAGTGGAGCACTG-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CAcCACAGTGGAGCAct Original Motif Reverse Complement RGWGSABCACWGTGRMGCMMYDBTGACCTB AGTGCTCCACTGTGDTG RGTGCWCCACTGTGRHGCMMYDBTGACCTB Direction: Forward Position #: 1 Overlap #: 17 Alignment: RGWGSABCACWGTGRMGCMMYDBTGACCTB AGTGCTCCACTGTGDTG------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CTCF Combined Motif Original Motif Original Motif RGTGCWCCACTGTGRHGCMMYDBTGACCTB YDRCCASYAGRKGGCRSYV RGTBSDCCACTRKGGGGCVVYVBTGACCTB Direction: Forward Position #: 4 Overlap #: 19 Alignment: RGTGCWCCACTGTGRHGCMMYDBTGACCTB ---YDRCCASYAGRKGGCRSYV-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Reverse Complement Reverse Complement BAGGTCABBMVBGCCCCYKAGTGGDSBACK TGRCCTKTGHCCKAB BAGGTCWSDCCTKYBHCCKASTGGDSBACK Direction: Forward Position #: 7 Overlap #: 15 Alignment: BAGGTCABBMVBGCCCCYKAGTGGDSBACK ------TGRCCTKTGHCCKAB--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- REST Combined Motif Reverse Complement Original Motif RGTBSDCCASTRGGDBMYAGGDSWGACCTB TTCAGCACCATGGACAGCKCC RGTKCASCACCRKGGVCARSGBCWGACCTB Direction: Forward Position #: 3 Overlap #: 21 Alignment: RGTBSDCCASTRGGDBMYAGGDSWGACCTB --TTCAGCACCATGGACAGCKCC------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 24 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCCCCGCSssk ESR1 Reverse Complement Reverse Complement BBSGGCGGGGBS MGGTCAGGGTGACCTRDBHV VBBKGRCSKGGBBMGGTCAG Direction: Backward Position #: 2 Overlap #: 12 Alignment: -------BBSGGCGGGGBS- MGGTCAGGGTGACCTRDBHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CTCF Combined Motif Original Motif Original Motif VBBKGRCSKGGBBMGGTCAG YDRCCASYAGRKGGCRSYV VBBBGRCCDSBAGRGGKCASYV Direction: Forward Position #: 4 Overlap #: 17 Alignment: VBBKGRCSKGGBBMGGTCAG-- ---YDRCCASYAGRKGGCRSYV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PPARGRXRA Original Motif Original Motif VBBBGRCCDSBAGRGGKCASYV BTRGGDCARAGGKCA VBVKGDCMRRGRKVRGKCASYV Direction: Forward Position #: 1 Overlap #: 15 Alignment: VBBBGRCCDSBAGRGGKCASYV BTRGGDCARAGGKCA------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR2 Reverse Complement Reverse Complement BMSTGYCKVYMCKKYGHCYVVV BAGGYCABHBTGACCKHV BAGKHCWGBCTGHCCKDBGHCYVVV Direction: Forward Position #: 4 Overlap #: 15 Alignment: ---BMSTGYCKVYMCKKYGHCYVVV BAGGYCABHBTGACCKHV------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Reverse Complement Original Motif VBVKGDCVDRGGHCAGBCWGDYCTB TTCAGCACCATGGACAGCKCC TBCAGSACCADGGACAGBBHSDYCTB Direction: Forward Position #: 2 Overlap #: 20 Alignment: -VBVKGDCVDRGGHCAGBCWGDYCTB TTCAGCACCATGGACAGCKCC----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- sscCCCGCGcs Combined Motif Original Motif Reverse Complement TBCAGSACCADGGACAGBBHSDYCTB SBCGCGGGGSB TBCAGSVCSCGGGVSRGBBHSDYCTB Direction: Forward Position #: 6 Overlap #: 11 Alignment: TBCAGSACCADGGACAGBBHSDYCTB -----SBCGCGGGGSB---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif gCGCGCsCgsG Original Motif Original Motif TBCAGSVCSCGGGVSRGBBHSDYCTB GCGCGCSCGCG BYGMGCSCGCGGGVSRGBBHSDYCTB Direction: Forward Position #: 1 Overlap #: 11 Alignment: TBCAGSVCSCGGGVSRGBBHSDYCTB GCGCGCSCGCG--------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssGCkTGCssk Combined Motif Original Motif Original Motif BYGMGCSCGCGGGVSRGBBHSDYCTB SSGCKTGCSSK BYGMGSGCGYGSGSBRGBBHSDYCTB Direction: Forward Position #: 5 Overlap #: 11 Alignment: BYGMGCSCGCGGGVSRGBBHSDYCTB ----SSGCKTGCSSK----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif cCGCGGrCACG Original Motif Original Motif BYGMGSGCGYGSGSBRGBBHSDYCTB CCGCGGRCACG BCGCGSRCRCGSGSBRGBBHSDYCTB Direction: Forward Position #: 1 Overlap #: 11 Alignment: BYGMGSGCGYGSGSBRGBBHSDYCTB CCGCGGRCACG--------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Esrrb Combined Motif Original Motif Reverse Complement BCGCGSRCRCGSGSBRGBBHSDYCTB TGACCTTGMBBB BCGYGRSCTTGVSVBRGBBHSDYCTB Direction: Forward Position #: 4 Overlap #: 12 Alignment: BCGCGSRCRCGSGSBRGBBHSDYCTB ---TGACCTTGMBBB----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 25 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wwCCAmAGTCmt CACTGTGrYrtCACAGTGswsCAcT Original Motif Original Motif DDCCAMAGTCHB CACTGTGRTRTCACAGTGSWSCACT SCACTHDYCACAGTSBWCACTGTGR Direction: Backward Position #: 6 Overlap #: 12 Alignment: --------DDCCAMAGTCHB----- CACTGTGRTRTCACAGTGSWSCACT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CagTGCTCCACTGTGgT Original Motif Original Motif SCACTHDYCACAGTSBWCACTGTGR CAGTGCTCCACTGTGBT CMRYKCTCCACWGTGBTCACTGTGR Direction: Forward Position #: 1 Overlap #: 17 Alignment: SCACTHDYCACAGTSBWCACTGTGR CAGTGCTCCACTGTGBT-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CAcCACAGTGGAGCAct Reverse Complement Original Motif MCACAGTGABCACWGTGGAGRMKRG CAHCACAGTGGAGCACT CAVCACAGTGRASMMHKTGGAGRMKRG Direction: Forward Position #: 3 Overlap #: 15 Alignment: --MCACAGTGABCACWGTGGAGRMKRG CAHCACAGTGGAGCACT---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AgTGCTCCACTGTGgTGTCACAgT Original Motif Original Motif CAVCACAGTGRASMMHKTGGAGRMKRG AGTGCTCCACTGTGGTGTCACAGT AGTGCWCCACWGTGGWGWCABWGKAGRMKRG Direction: Forward Position #: 5 Overlap #: 20 Alignment: ----CAVCACAGTGRASMMHKTGGAGRMKRG AGTGCTCCACTGTGGTGTCACAGT------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- HNF4A Combined Motif Reverse Complement Reverse Complement CMRYKCTRCWBTGWCWCCACWGTGGWGCACT TGMYCTTTGBCCK CMRYKCTGCHCTKTSDCCACWGTGGWGCACT Direction: Forward Position #: 7 Overlap #: 13 Alignment: CMRYKCTRCWBTGWCWCCACWGTGGWGCACT ------TGMYCTTTGBCCK------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TGGAGCACTGTGACAcCACAGTGg Combined Motif Original Motif Original Motif CMRYKCTGCHCTKTSDCCACWGTGGWGCACT TGGAGCACTGTGACAVCACAGTGG CYRBWSYACTSTGWCACCACAGTGGWGCACT Direction: Forward Position #: 2 Overlap #: 24 Alignment: CMRYKCTGCHCTKTSDCCACWGTGGWGCACT -TGGAGCACTGTGACAVCACAGTGG------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Reverse Complement Reverse Complement AGTGCWCCACTGTGGTGWCASAGTKSWBMMG GGYGCTGTCCATGGTGCTGAA GGHGYKSTCCAYKGTGCTGWHASAGTKSWBMMG Direction: Forward Position #: 3 Overlap #: 19 Alignment: --AGTGCWCCACTGTGGTGWCASAGTKSWBMMG GGYGCTGTCCATGGTGCTGAA------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TgTGgTGTCACAGTGCTCC Combined Motif Original Motif Reverse Complement GGHGYKSTCCAYKGTGCTGWHASAGTKSWBMMG GGAGCACTGTGACACCACA GGHGYGSWSCACTGTGMYRHCACAGTKSWBMMG Direction: Forward Position #: 6 Overlap #: 19 Alignment: GGHGYKSTCCAYKGTGCTGWHASAGTKSWBMMG -----GGAGCACTGTGACACCACA--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Reverse Complement Reverse Complement CYRBWSYACTGTGDKKYCACAGTGSWSCKCHCC MGGTCAGGGTGACCTRDBHV CYRBWSYASKBYRDKKTSACMKDGSHVCKCHCC Direction: Forward Position #: 8 Overlap #: 20 Alignment: CYRBWSYACTGTGDKKYCACAGTGSWSCKCHCC -------MGGTCAGGGTGACCTRDBHV------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR1H2RXRA Combined Motif Original Motif Reverse Complement CYRBWSYASKBYRDKKTSACMKDGSHVCKCHCC GTTGACCTTTGACCTTT CCGKTGACCTTKGACCKBTCYRBWSYASKBYRD Direction: Backward Position #: 3 Overlap #: 17 Alignment: CYRBWSYASKBYRDKKTSACMKDGSHVCKCHCC --------------GTTGACCTTTGACCTTT-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 26 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CAcCACAGTGGAGCAct AgTGCTCCACTGTGgTGTCACAgT Original Motif Reverse Complement CAHCACAGTGGAGCACT ACTGTGACACCACAGTGGAGCACT ACTGTGACACCACAGTGGAGCACT Direction: Forward Position #: 8 Overlap #: 17 Alignment: -------CAHCACAGTGGAGCACT ACTGTGACACCACAGTGGAGCACT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACTGTGrYrtCACAGTGswsCAcT Reverse Complement Reverse Complement AGTGCTCCACTGTGGTGTCACAGT AGTGSWSCACTGTGAMAMCACAGTG AGTGCTSCACTGTGVYRTCACAGTG Direction: Forward Position #: 1 Overlap #: 24 Alignment: AGTGCTCCACTGTGGTGTCACAGT- AGTGSWSCACTGTGAMAMCACAGTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Original Motif Reverse Complement AGTGCTSCACTGTGVYRTCACAGTG GGYGCTGTCCATGGTGCTGAA GGHGYKSTCCAYKGTGCTGHMACAGTG Direction: Forward Position #: 3 Overlap #: 19 Alignment: --AGTGCTSCACTGTGVYRTCACAGTG GGYGCTGTCCATGGTGCTGAA------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TgTGgTGTCACAGTGCTCC Combined Motif Original Motif Reverse Complement GGHGYKSTCCAYKGTGCTGHMACAGTG GGAGCACTGTGACACCACA GGHGYGGWSCACTGTGMYRHCACAGTG Direction: Forward Position #: 6 Overlap #: 19 Alignment: GGHGYKSTCCAYKGTGCTGHMACAGTG -----GGAGCACTGTGACACCACA--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CTCF Combined Motif Original Motif Reverse Complement GGHGYGGWSCACTGTGMYRHCACAGTG BMSMGCCYMCTKSTGGMHM GGHGYDSMGCMCHSTGVTGVCAMAGTG Direction: Forward Position #: 5 Overlap #: 19 Alignment: GGHGYGGWSCACTGTGMYRHCACAGTG ----BMSMGCCYMCTKSTGGMHM---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TGGAGCACTGTGACAcCACAGTGg Reverse Complement Reverse Complement CACTRTGVCAVCASHGRGCYSHMCHCC CCACTGTGVTGTCACAGTGCTCCA CCACTGTGVYRDCACAGDGCTCCACHCC Direction: Forward Position #: 2 Overlap #: 23 Alignment: -CACTRTGVCAVCASHGRGCYSHMCHCC CCACTGTGVTGTCACAGTGCTCCA---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CagTGCTCCACTGTGgT Original Motif Reverse Complement CCACTGTGVYRDCACAGDGCTCCACHCC ABCACAGTGGAGCACTG ACCACWGTGGAGYMMBRGDGCTCCACHCC Direction: Forward Position #: 2 Overlap #: 16 Alignment: -CCACTGTGVYRDCACAGDGCTCCACHCC ABCACAGTGGAGCACTG------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- AmTGTGACACCACAGT Combined Motif Original Motif Reverse Complement ACCACWGTGGAGYMMBRGDGCTCCACHCC ACTGTGGTGTCACART ACCACTGTGGTGTCACAGTGCTCCACHCC Direction: Forward Position #: 4 Overlap #: 16 Alignment: ACCACWGTGGAGYMMBRGDGCTCCACHCC ---ACTGTGGTGTCACART---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwCCAmAGTCmt Original Motif Reverse Complement ACCACTGTGGTGTCACAGTGCTCCACHCC VDGACTRTGGDD AVSACTGTGGWKTCACAGTGCTCCACHCC Direction: Forward Position #: 1 Overlap #: 12 Alignment: ACCACTGTGGTGTCACAGTGCTCCACHCC VDGACTRTGGDD----------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif HNF4A Original Motif Reverse Complement AVSACTGTGGWKTCACAGTGCTCCACHCC TGMYCTTTGBCCK DBVMCTKTGGHBTCACAGTGCTCCACHCC Direction: Forward Position #: 1 Overlap #: 13 Alignment: AVSACTGTGGWKTCACAGTGCTCCACHCC TGMYCTTTGBCCK---------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 27 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- AgTGCTCCACTGTGgTGTCACAgT CACTGTGrYrtCACAGTGswsCAcT Original Motif Reverse Complement AGTGCTCCACTGTGGTGTCACAGT AGTGSWSCACTGTGAMAMCACAGTG ARKKGMKCMMYKKKRVWVYMMMRKK Direction: Forward Position #: 2 Overlap #: 24 Alignment: -AGTGCTCCACTGTGGTGTCACAGT AGTGSWSCACTGTGAMAMCACAGTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TGGAGCACTGTGACAcCACAGTGg Combined Motif Original Motif Original Motif ARKKGMKCMMYKKKRVWVYMMMRKK TGGAGCACTGTGACAVCACAGTGG ARTGGAKCACTGTGACAVCACAGTGG Direction: Forward Position #: 3 Overlap #: 23 Alignment: ARKKGMKCMMYKKKRVWVYMMMRKK- --TGGAGCACTGTGACAVCACAGTGG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- REST Combined Motif Original Motif Original Motif ARTGGAKCACTGTGACAVCACAGTGG TTCAGCACCATGGACAGCKCC ARTGGAKCACTGTKDCAGCACMRTGGACAGCKCC Direction: Forward Position #: 14 Overlap #: 13 Alignment: ARTGGAKCACTGTGACAVCACAGTGG-------- -------------TTCAGCACCATGGACAGCKCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TgTGgTGTCACAGTGCTCC Original Motif Original Motif ARTGGAKCACTGTKDCAGCACMRTGGACAGCKCC TGTGGTGTCACAGTGCTCC TGTRGTGKMDCASTGYTHCAGCACMRTGGACAGCKCC Direction: Forward Position #: 4 Overlap #: 16 Alignment: ---ARTGGAKCACTGTKDCAGCACMRTGGACAGCKCC TGTGGTGTCACAGTGCTCC------------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Reverse Complement Original Motif GGYGCTGTCCAKRGTGCTGDAMCASTGDRRCACMACA YDRCCASYAGRKGGCRSYV BGVSCWSTMSRKGGYGCTRDAMCASTGDRRCACMACA Direction: Forward Position #: 1 Overlap #: 19 Alignment: GGYGCTGTCCAKRGTGCTGDAMCASTGDRRCACMACA YDRCCASYAGRKGGCRSYV------------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CAcCACAGTGGAGCAct Combined Motif Reverse Complement Original Motif TGTRGTGKMDCASTGYTHMAGCMCCYKSYASWGSBCB CAHCACAGTGGAGCACT TGTRGYRBCACAGTGBWGCASHMCCYKSYASWGSBCB Direction: Forward Position #: 6 Overlap #: 17 Alignment: TGTRGTGKMDCASTGYTHMAGCMCCYKSYASWGSBCB -----CAHCACAGTGGAGCACT--------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CagTGCTCCACTGTGgT Combined Motif Original Motif Reverse Complement TGTRGYRBCACAGTGBWGCASHMCCYKSYASWGSBCB ABCACAGTGGAGCACTG TGTRGYABCACAGTGGAGCACTVCCYKSYASWGSBCB Direction: Forward Position #: 7 Overlap #: 17 Alignment: TGTRGYRBCACAGTGBWGCASHMCCYKSYASWGSBCB ------ABCACAGTGGAGCACTG-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AmTGTGACACCACAGT Original Motif Original Motif TGTRGYABCACAGTGGAGCACTVCCYKSYASWGSBCB AMTGTGACACCACAGT AMTGTGACACCACAGTGGAGCACTVCCYKSYASWGSBCB Direction: Forward Position #: 3 Overlap #: 14 Alignment: --TGTRGYABCACAGTGGAGCACTVCCYKSYASWGSBCB AMTGTGACACCACAGT----------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Original Motif Original Motif AMTGTGACACCACAGTGGAGCACTVCCYKSYASWGSBCB VDBHMAGGTCACCCTGACCY AMTGTGACABCACAGKKSASCMYBVCCYKSYASWGSBCB Direction: Forward Position #: 9 Overlap #: 20 Alignment: AMTGTGACACCACAGTGGAGCACTVCCYKSYASWGSBCB --------VDBHMAGGTCACCCTGACCY----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Original Motif Reverse Complement AMTGTGACABCACAGKKSASCMYBVCCYKSYASWGSBCB BAGGYCABHBTGACCKHV AMTGTGACAGSHCABBBTRVCMKDVCCYKSYASWGSBCB Direction: Forward Position #: 8 Overlap #: 18 Alignment: AMTGTGACABCACAGKKSASCMYBVCCYKSYASWGSBCB -------BAGGYCABHBTGACCKHV-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 28 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssGCkTGCssk gCGCGCsCgsG Original Motif Original Motif SSGCKTGCSSK GCGCGCSCGCG SCGCGYGCSSG Direction: Backward Position #: 1 Overlap #: 11 Alignment: SSGCKTGCSSK GCGCGCSCGCG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCCCCGCSssk Combined Motif Reverse Complement Original Motif CSSGCKCGCGS SBCCCCGCCSBB CSSSCBCGCSSBB Direction: Forward Position #: 2 Overlap #: 10 Alignment: CSSGCKCGCGS-- -SBCCCCGCCSBB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif sscCCCGCGcs Reverse Complement Original Motif BBSSGCGBGSSSG BSCCCCGCGBS BBSCSCGCGSSSG Direction: Forward Position #: 1 Overlap #: 11 Alignment: BBSSGCGBGSSSG BSCCCCGCGBS-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif cCGCGGrCACG Reverse Complement Reverse Complement CSSSCGCGSGSBB CGTGKCCGCGG CGBGYSCGCGSBB Direction: Forward Position #: 1 Overlap #: 11 Alignment: CSSSCGCGSGSBB CGTGKCCGCGG-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Reverse Complement Reverse Complement BBSCGCGSKCVCG BMSMGCCYMCTKSTGGMHM BVSCGCSSVCDBGTGGMHM Direction: Forward Position #: 1 Overlap #: 13 Alignment: BBSCGCGSKCVCG------ BMSMGCCYMCTKSTGGMHM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Esrrb Reverse Complement Reverse Complement YDRCCACBDGVSSGCGSVV TGACCTTGMBBB TGACCWYSHGBBSGCGSVV Direction: Forward Position #: 1 Overlap #: 12 Alignment: YDRCCACBDGVSSGCGSVV TGACCTTGMBBB------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR2 Reverse Complement Reverse Complement BVSCGCSBBCHSMWGGTCA BAGGYCABHBTGACCKHV BMGVBCVBBBTGAHSGTVA Direction: Forward Position #: 1 Overlap #: 18 Alignment: BVSCGCSBBCHSMWGGTCA BAGGYCABHBTGACCKHV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- REST Combined Motif Original Motif Original Motif BMGVBCVBBBTGAHSGTVA TTCAGCACCATGGACAGCKCC BMGBBCAGBAYSAHGGWCAGCKCC Direction: Forward Position #: 4 Overlap #: 16 Alignment: BMGVBCVBBBTGAHSGTVA----- ---TTCAGCACCATGGACAGCKCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Original Motif Reverse Complement BMGBBCAGBAYSAHGGWCAGCKCC TGRCCTKTGHCCKAB BHGDYCWKTVYCMBVGWCAGCKCC Direction: Forward Position #: 2 Overlap #: 15 Alignment: BMGBBCAGBAYSAHGGWCAGCKCC -TGRCCTKTGHCCKAB-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif HNF4A Reverse Complement Reverse Complement GGYGCTGWCVVRGKVAYWGKDCHB TGMYCTTTGBCCK KGHBCTKTSBHVGKVAYWGKDCHB Direction: Forward Position #: 1 Overlap #: 13 Alignment: GGYGCTGWCVVRGKVAYWGKDCHB TGMYCTTTGBCCK----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 29 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- cCGCGGrCACG gCGCGCsCgsG Original Motif Original Motif CCGCGGRCACG GCGCGCSCGCG SCGCGSRCRCG Direction: Backward Position #: 1 Overlap #: 11 Alignment: CCGCGGRCACG GCGCGCSCGCG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Reverse Complement Original Motif CGKGMSCGCGS TTCAGCACCATGGACAGCKCC CMBGGASMGCGSTTCAGCACC Direction: Backward Position #: 2 Overlap #: 11 Alignment: ---------CGKGMSCGCGS- TTCAGCACCATGGACAGCKCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 30 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- taaacgatgcc NR1H2RXRA Original Motif Reverse Complement TAAACGATGCC GTTGACCTTTGACCTTT GTTGWMMWYKRWSCYTT Direction: Forward Position #: 5 Overlap #: 11 Alignment: ----TAAACGATGCC-- GTTGACCTTTGACCTTT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR2F1 Combined Motif Original Motif Original Motif GTTGWMMWYKRWSCYTT TGAMCTTTGMMCYT GTTGAMCTTTGHVCYTT Direction: Forward Position #: 3 Overlap #: 14 Alignment: GTTGWMMWYKRWSCYTT --TGAMCTTTGMMCYT- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif atactttggc Reverse Complement Reverse Complement AAKGVHCAAAGRTCAAC GCCAAAGTAT GTATRCMRAWAAKGVHCAAAG Direction: Backward Position #: 5 Overlap #: 6 Alignment: AAKGVHCAAAGRTCAAC---- -----------GCCAAAGTAT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 31 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ctatacggacg srACyCCGAyr Original Motif Original Motif CTATACGGACG SRACYCCGAYR CDAYHCSGACG Direction: Backward Position #: 1 Overlap #: 11 Alignment: CTATACGGACG SRACYCCGAYR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- taaacgatgcc Combined Motif Original Motif Reverse Complement CDAYHCSGACG GGCATCGTTTA CDAYHCSGRCRTCGTTTA Direction: Forward Position #: 8 Overlap #: 4 Alignment: CDAYHCSGACG------- -------GGCATCGTTTA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- MIZF Combined Motif Original Motif Reverse Complement CDAYHCSGRCRTCGTTTA GCGGACGTTV CDAYDCGGACRTYGTTTA Direction: Forward Position #: 5 Overlap #: 10 Alignment: CDAYHCSGRCRTCGTTTA ----GCGGACGTTV---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- atactttggc Combined Motif Reverse Complement Original Motif TAAACKAMGTCCGHKTDG ATACTTTGGC TAWACTWYGKCCGHKTDG Direction: Forward Position #: 2 Overlap #: 10 Alignment: TAAACKAMGTCCGHKTDG -ATACTTTGGC------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- cCGCGGrCACG Combined Motif Original Motif Reverse Complement TAWACTWYGKCCGHKTDG CGTGKCCGCGG DGHDTGKCCGCKTTAWAC Direction: Backward Position #: 3 Overlap #: 11 Alignment: TAWACTWYGKCCGHKTDG -----CGTGKCCGCGG-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 32 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- gCGCGCsCgsG cCGCGGrCACG Original Motif Original Motif GCGCGCSCGCG CCGCGGRCACG SCGCGSRCRCG Direction: Backward Position #: 1 Overlap #: 11 Alignment: GCGCGCSCGCG CCGCGGRCACG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGCkTGCssk Reverse Complement Reverse Complement CGKGMSCGCGS YSSGCAYGCSS CSBGCRCGCGS Direction: Forward Position #: 1 Overlap #: 11 Alignment: CGKGMSCGCGS YSSGCAYGCSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif sscCCCGCGcs Original Motif Reverse Complement CSBGCRCGCGS SBCGCGGGGSB CSCGCGSGSGS Direction: Forward Position #: 1 Overlap #: 11 Alignment: CSBGCRCGCGS SBCGCGGGGSB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCCCCGCSssk Combined Motif Original Motif Original Motif CSCGCGSGSGS SBCCCCGCCSBB CSSSCSCGCSSBB Direction: Forward Position #: 2 Overlap #: 10 Alignment: CSCGCGSGSGS-- -SBCCCCGCCSBB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CTCF Combined Motif Original Motif Reverse Complement CSSSCSCGCSSBB BMSMGCCYMCTKSTGGMHM CBVSCGCSCCCTKSTGGMHM Direction: Forward Position #: 2 Overlap #: 12 Alignment: CSSSCSCGCSSBB------- -BMSMGCCYMCTKSTGGMHM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Original Motif Original Motif CBVSCGCSCCCTKSTGGMHM VDBHMAGGTCACCCTGACCY CBVSCVMGSBCWBSBKGMCMY Direction: Forward Position #: 2 Overlap #: 19 Alignment: CBVSCGCSCCCTKSTGGMHM- -VDBHMAGGTCACCCTGACCY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- MIZF Combined Motif Original Motif Reverse Complement CBVSCVMGSBCWBSBKGMCMY GCGGACGTTV CBVSCVMGSBCWBSCGGACVTTV Direction: Forward Position #: 14 Overlap #: 8 Alignment: CBVSCVMGSBCWBSBKGMCMY-- -------------GCGGACGTTV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Myc Original Motif Original Motif CBVSCVMGSBCWBSCGGACVTTV VGCACGTGGH CVCACGHGGHCWBSCGGACVTTV Direction: Forward Position #: 1 Overlap #: 10 Alignment: CBVSCVMGSBCWBSCGGACVTTV VGCACGTGGH------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Mycn Original Motif Original Motif CVCACGHGGHCWBSCGGACVTTV HSCACGTGGC HSCACGTGGCCWBSCGGACVTTV Direction: Forward Position #: 1 Overlap #: 10 Alignment: CVCACGHGGHCWBSCGGACVTTV HSCACGTGGC------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ctatacggacg Combined Motif Original Motif Original Motif HSCACGTGGCCWBSCGGACVTTV CTATACGGACG TTVCYATACGGACGHSCACGTGG Direction: Backward Position #: 4 Overlap #: 11 Alignment: HSCACGTGGCCWBSCGGACVTTV ---------CTATACGGACG--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 33 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- srACyCCGAyr ESR1 Reverse Complement Reverse Complement KKTCGGKGTKS MGGTCAGGGTGACCTRDBHV CCTRDBHVKGTCRGKGTGVM Direction: Backward Position #: 9 Overlap #: 11 Alignment: -KKTCGGKGTKS-------- MGGTCAGGGTGACCTRDBHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TGGAGCACTGTGACAcCACAGTGg Original Motif Reverse Complement CCTRDBHVKGTCRGKGTGVM CCACTGTGVTGTCACAGTGCTCCA CCMYTGTVVKGTCASDGTGCWCCA Direction: Forward Position #: 2 Overlap #: 20 Alignment: -CCTRDBHVKGTCRGKGTGVM--- CCACTGTGVTGTCACAGTGCTCCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR2 Reverse Complement Reverse Complement TGGWGCACDSTGACRVVACAKYGG BAGGYCABHBTGACCKHV TRGDBCACBSTGACVBHVCAKYGG Direction: Forward Position #: 1 Overlap #: 18 Alignment: TGGWGCACDSTGACRVVACAKYGG BAGGYCABHBTGACCKHV------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TgTGgTGTCACAGTGCTCC Reverse Complement Reverse Complement CCMYTGBDBVGTCASVGTGBHCMA GGAGCACTGTGACACCACA GGASCACTGTGACRYCACAGTGBHCMA Direction: Forward Position #: 4 Overlap #: 16 Alignment: ---CCMYTGBDBVGTCASVGTGBHCMA GGAGCACTGTGACACCACA-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACTGTGrYrtCACAGTGswsCAcT Original Motif Reverse Complement GGASCACTGTGACRYCACAGTGBHCMA AGTGSWSCACTGTGAMAMCACAGTG AGTGGASCACTGTGACAHCACAGTGBHCMA Direction: Forward Position #: 4 Overlap #: 22 Alignment: ---GGASCACTGTGACRYCACAGTGBHCMA AGTGSWSCACTGTGAMAMCACAGTG----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Reverse Complement Reverse Complement TRGDBCACTGTGDTGTCACAGTGSTCCACT GGYGCTGTCCATGGTGCTGAA GGYGCTGTCCAYKGTGCTGHMACAGTGSTCCACT Direction: Forward Position #: 5 Overlap #: 17 Alignment: ----TRGDBCACTGTGDTGTCACAGTGSTCCACT GGYGCTGTCCATGGTGCTGAA------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Results created by MOTIFSIM on 11-19-2016 15:10:45 Runtime: 649.633 seconds MOTIFSIM is written by Ngoc Tam L. 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