**************************************************************************************************************************************************************************************************** MOTIFSIM - Motif Similarity Detection Tool Version 2.1 **************************************************************************************************************************************************************************************************** INPUT **************************************************************************************************************************************************************************************************** Input Parameters Number of files: 4 Number of top significant motifs: 10 Number of best matches: 5 Similarity cutoff: >= 0.75 Matching motif database: UniProbe Mus Musculus Phylogenetic tree: Yes Combined similar motifs: Yes Output file type: All Output file format: All Input files and motif counts File name Count of motifs Dataset # DREME_DM254.txt 45 1 MEME-CHIP_DM254.txt 24 2 PScanChIP_DM254.txt 63 3 RSAT_peak-motifs_DM254.txt 39 4 **************************************************************************************************************************************************************************************************** RESULTS **************************************************************************************************************************************************************************************************** *************************************************************** Combined Motifs for Top Best Match Motif ID 1 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 1 Motif 46 Original Motif Original Motif AGRKGGCR AGRKGGCR AGRKGGCR Direction: Forward Position #: 1 Overlap #: 8 Alignment: AGRKGGCR AGRKGGCR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asCAGrkGGCrsy Reverse Complement Reverse Complement KGCCYKCT BSKGCCCMCTGST BSKGCCYBCTGST Direction: Forward Position #: 3 Overlap #: 8 Alignment: --KGCCYKCT--- BSKGCCCMCTGST ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wgGCCAshAGrGGGCrsy Original Motif Reverse Complement BSKGCCYBCTGST KBKGCCCKCTHGTGGCHH BSKGCCCBCTBSTGGCHH Direction: Forward Position #: 1 Overlap #: 13 Alignment: BSKGCCYBCTGST----- KBKGCCCKCTHGTGGCHH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CasCAGrGGGCrsy Original Motif Reverse Complement BSKGCCCBCTBSTGGCHH BSKGCCCKCTGGTG BSKGCCCKCTGSTGGCHH Direction: Forward Position #: 1 Overlap #: 14 Alignment: BSKGCCCBCTBSTGGCHH BSKGCCCKCTGGTG---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif gwGGCCAGmAGAGGGCrby Original Motif Reverse Complement BSKGCCCKCTGSTGGCHH KBKGCCCTCTYCTGGCCHV KBKGCCCTCTBSTGGCCHV Direction: Forward Position #: 1 Overlap #: 18 Alignment: BSKGCCCKCTGSTGGCHH- KBKGCCCTCTYCTGGCCHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asyAGrkGGCRGCAga Original Motif Reverse Complement KBKGCCCTCTBSTGGCCHV HBTGCTGCCYMCTKST BBTGCYSYCTVCTGGYCHV Direction: Forward Position #: 1 Overlap #: 16 Alignment: KBKGCCCTCTBSTGGCCHV HBTGCTGCCYMCTKST--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 2 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 2 Motif 68 Original Motif Original Motif AAAAHAAA WAAWAAAWAWWWAA WAAWAAADAAAWAA Direction: Forward Position #: 4 Overlap #: 8 Alignment: ---AAAAHAAA--- WAAWAAAWAWWWAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif waATwAAAATAww Original Motif Original Motif WAAWAAADAAAWAA DHATWAAAATAHD WAATAAAAAWAWAA Direction: Forward Position #: 1 Overlap #: 13 Alignment: WAAWAAADAAAWAA DHATWAAAATAHD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 52 Original Motif Original Motif WAATAAAAAWAWAA AAATAAAW WAATAAAWAWAWAA Direction: Forward Position #: 1 Overlap #: 8 Alignment: WAATAAAAAWAWAA AAATAAAW------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtATTTTTAww Reverse Complement Original Motif TTWTWTWTTTATTW DTATTTTTAWW TTATTTTTWTATTW Direction: Forward Position #: 1 Overlap #: 11 Alignment: TTWTWTWTTTATTW DTATTTTTAWW--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTwAAAAww Original Motif Reverse Complement TTATTTTTWTATTW HHTTTTWADD TWWTTTWWWTATTW Direction: Forward Position #: 1 Overlap #: 10 Alignment: TTATTTTTWTATTW HHTTTTWADD---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 3 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 3 Motif 24 Original Motif Reverse Complement CACACACA CACCCACA CACMCACA Direction: Forward Position #: 1 Overlap #: 8 Alignment: CACACACA CACCCACA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 31 Reverse Complement Reverse Complement TGTGYGTG TGTKCATG TGTGCRTG Direction: Forward Position #: 1 Overlap #: 8 Alignment: TGTGYGTG TGTKCATG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif T Original Motif Original Motif TGTGCRTG CTAGGTGTGAA CTRKGYGTGAA Direction: Forward Position #: 2 Overlap #: 8 Alignment: -TGTGCRTG-- CTAGGTGTGAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 64 Combined Motif Original Motif Reverse Complement CTRKGYGTGAA TGMATATG CTGBRTRTGAA Direction: Forward Position #: 2 Overlap #: 8 Alignment: CTRKGYGTGAA -TGMATATG-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RUNX1 Original Motif Reverse Complement CTGBRTRTGAA AAACCACAKVB AAACCACWGVVTRTGAA Direction: Forward Position #: 7 Overlap #: 5 Alignment: ------CTGBRTRTGAA AAACCACAKVB------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 4 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 4 wwTwAAAAww Reverse Complement Original Motif WTWWAAA DDTWAAAAHH HHWTWAAAAD Direction: Backward Position #: 3 Overlap #: 7 Alignment: -WTWWAAA-- DDTWAAAAHH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- waATwAAAATAww Combined Motif Original Motif Original Motif HHWTWAAAAD DHATWAAAATAHD HHWWTAAAAATAHD Direction: Forward Position #: 2 Overlap #: 9 Alignment: HHWTWAAAAD---- -DHATWAAAATAHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtATTTTTAww Reverse Complement Original Motif DHTATTTTTAWWHH DTATTTTTAWW DHWWTTTTWWWWHH Direction: Forward Position #: 1 Overlap #: 11 Alignment: DHTATTTTTAWWHH DTATTTTTAWW--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 68 Combined Motif Reverse Complement Original Motif HHWWWWAAAAWWHD WAAWAAAWAWWWAA HHWAAWAAAAAWWWAA Direction: Forward Position #: 3 Overlap #: 12 Alignment: HHWWWWAAAAWWHD-- --WAAWAAAWAWWWAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 52 Reverse Complement Reverse Complement TTWWWTTTTTWTTWHH WTTTATTT TTTTATTTTTWTTWHH Direction: Forward Position #: 1 Overlap #: 8 Alignment: TTWWWTTTTTWTTWHH WTTTATTT-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 5 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 5 Motif 59 Original Motif Original Motif CCCCDCCC CCCCRCCC CCCCRCCC Direction: Forward Position #: 1 Overlap #: 8 Alignment: CCCCDCCC CCCCRCCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif csCSCCdCCCcs Reverse Complement Reverse Complement GGGKGGGG VDGGGDGGGGBV GGGGGGGGGGBV Direction: Forward Position #: 1 Overlap #: 8 Alignment: GGGKGGGG---- VDGGGDGGGGBV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Klf4 Reverse Complement Reverse Complement VBCCCCCCCCCC GCCYCMCCCD BCCCCCCCCCCC Direction: Forward Position #: 1 Overlap #: 10 Alignment: VBCCCCCCCCCC GCCYCMCCCD-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- csCsCCTCCcc Combined Motif Reverse Complement Reverse Complement GGGGGGGGGGGB BDGGAGGGGBV GGVGGGRGGGGBV Direction: Forward Position #: 3 Overlap #: 10 Alignment: GGGGGGGGGGGB- --BDGGAGGGGBV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif SP1 Original Motif Reverse Complement GGVGGGRGGGGBV GGGGGYGGGG GGGGGGRGGGGBV Direction: Forward Position #: 1 Overlap #: 10 Alignment: GGVGGGRGGGGBV GGGGGYGGGG--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 6 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 6 Motif 40 Original Motif Reverse Complement CTGGRRA CTGGGAMT CTGGGAAT Direction: Forward Position #: 1 Overlap #: 7 Alignment: CTGGRRA- CTGGGAMT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 69 Original Motif Original Motif CTGGGAAT CCTGGARCTGGAGT CYKGGAAYTGGAGT Direction: Forward Position #: 1 Overlap #: 8 Alignment: CTGGGAAT------ CCTGGARCTGGAGT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Hand1Tcfe2a Reverse Complement Reverse Complement ACTCCAMTTCCYMG AWRCCAGAMB AHKCCARWHCCYMG Direction: Forward Position #: 1 Overlap #: 10 Alignment: ACTCCAMTTCCYMG AWRCCAGAMB---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif agrCCAGmAGrg Original Motif Original Motif AHKCCARWHCCYMG HVGCCAGMAGRG AVRCCAGMAGMBMG Direction: Forward Position #: 1 Overlap #: 12 Alignment: AHKCCARWHCCYMG HVGCCAGMAGRG-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 33 Reverse Complement Original Motif CYVRCTYCTGGMVT CTGGCTWC CTGGCTTCTGGMVT Direction: Forward Position #: 1 Overlap #: 8 Alignment: CYVRCTYCTGGMVT CTGGCTWC------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 7 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 7 Motif 2 Reverse Complement Reverse Complement TTTMCT TTTDTTTT TTTVYTTT Direction: Forward Position #: 1 Overlap #: 6 Alignment: TTTMCT-- TTTDTTTT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 32 Reverse Complement Original Motif AAAKVAAA KAATAAA DAATAAAA Direction: Forward Position #: 1 Overlap #: 7 Alignment: AAAKVAAA KAATAAA- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 52 Reverse Complement Reverse Complement TTTTATTH WTTTATTT TTTTATTW Direction: Forward Position #: 1 Overlap #: 8 Alignment: TTTTATTH WTTTATTT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 68 Reverse Complement Original Motif WAATAAAA WAAWAAAWAWWWAA WAATAAAWAWWWAA Direction: Forward Position #: 1 Overlap #: 8 Alignment: WAATAAAA------ WAAWAAAWAWWWAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stat3 Combined Motif Reverse Complement Reverse Complement TTWWWTWTTTATTW CTTCCTGGAA TTWWWTWTTTMTTCCTGGAA Direction: Forward Position #: 11 Overlap #: 4 Alignment: TTWWWTWTTTATTW------ ----------CTTCCTGGAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 8 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 8 waATwAAAATAww Original Motif Original Motif AAATAH DHATWAAAATAHD DAAATAHDHATWA Direction: Backward Position #: 2 Overlap #: 6 Alignment: ------AAATAH- DHATWAAAATAHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtATTTTTAww Reverse Complement Original Motif TWATHDHTATTTD DTATTTTTAWW TWATTTTTATTTD Direction: Forward Position #: 1 Overlap #: 11 Alignment: TWATHDHTATTTD DTATTTTTAWW-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 68 Reverse Complement Original Motif DAAATAAAAATWA WAAWAAAWAWWWAA WAAWWAAWAAWWAA Direction: Forward Position #: 1 Overlap #: 13 Alignment: DAAATAAAAATWA- WAAWAAAWAWWWAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 52 Original Motif Original Motif WAAWWAAWAAWWAA AAATAAAW WAATAAAWAAWWAA Direction: Forward Position #: 1 Overlap #: 8 Alignment: WAAWWAAWAAWWAA AAATAAAW------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 9 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 9 ctCTrsyGCCmCCTast Original Motif Reverse Complement GGTGGCWS ASTAGGYGGCMSCAGDD ASTAGGTGGCHSCAGDD Direction: Forward Position #: 5 Overlap #: 8 Alignment: ----GGTGGCWS----- ASTAGGYGGCMSCAGDD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif myrGYGCCmCCTast Original Motif Reverse Complement ASTAGGTGGCHSCAGDD ASTAGGYGGCGCTBB ASTAGGTGGCDCBAGDD Direction: Forward Position #: 1 Overlap #: 15 Alignment: ASTAGGTGGCHSCAGDD ASTAGGYGGCGCTBB-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asyAGrkGGCRGCAga Original Motif Original Motif ASTAGGTGGCDCBAGDD ASYAGRKGGCAGCABH ASYAGGTGGCRSCABDD Direction: Forward Position #: 1 Overlap #: 16 Alignment: ASTAGGTGGCDCBAGDD ASYAGRKGGCAGCABH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asCAGrkGGCrsy Original Motif Original Motif ASYAGGTGGCRSCABDD ASCAGRGGGCRSB ASCAGGKGGCRSBABDD Direction: Forward Position #: 1 Overlap #: 13 Alignment: ASYAGGTGGCRSCABDD ASCAGRGGGCRSB---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Reverse Complement Reverse Complement HDBTBSKGCCYCCTGST BMSMGCCYMCTKSTGGMHM BHSHGCYSCCTVCTGGHHM Direction: Forward Position #: 1 Overlap #: 17 Alignment: HDBTBSKGCCYCCTGST-- BMSMGCCYMCTKSTGGMHM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 10 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 10 Motif 49 Reverse Complement Reverse Complement GAGGCCAG GAGGCCAG GAGGCCAG Direction: Forward Position #: 1 Overlap #: 8 Alignment: GAGGCCAG GAGGCCAG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 33 Original Motif Reverse Complement GAGGCCAG GWAGCCAG GARGCCAG Direction: Forward Position #: 1 Overlap #: 8 Alignment: GAGGCCAG GWAGCCAG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AgmAGAGGGCrscAGak Reverse Complement Reverse Complement CTGGCKTC RTCTGSTGCCCTCTYCT RTCTGGYGYCCTCTYCT Direction: Forward Position #: 3 Overlap #: 8 Alignment: --CTGGCKTC------- RTCTGSTGCCCTCTYCT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif gwGGCCAGmAGAGGGCrby Original Motif Reverse Complement RTCTGGYGYCCTCTYCT KBKGCCCTCTYCTGGCCHV KBKGCCCTCTTCTGGCSHCCTCTYCT Direction: Forward Position #: 10 Overlap #: 10 Alignment: ---------RTCTGGYGYCCTCTYCT KBKGCCCTCTYCTGGCCHV------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif shAGrGGGCAgy Original Motif Reverse Complement KBKGCCCTCTTCTGGCSHCCTCTYCT DBTGCCCKCTDS DBTGCCCTCTDCTGGCSHCCTCTYCT Direction: Forward Position #: 1 Overlap #: 12 Alignment: KBKGCCCTCTTCTGGCSHCCTCTYCT DBTGCCCKCTDS-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 11 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 11 Motif 63 Original Motif Reverse Complement CTBCCTCY CWCCCTCT CTCCCTCT Direction: Backward Position #: 1 Overlap #: 8 Alignment: CTBCCTCY CWCCCTCT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 17 Original Motif Original Motif CTCCCTCT CCDCCTCC CYBCCTCY Direction: Forward Position #: 1 Overlap #: 8 Alignment: CTCCCTCT CCDCCTCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yvTGCyGCCmCCwGgtG Reverse Complement Reverse Complement KGAGGBKG CDCCWGGTGGCAGCAVV CDBSAGGBGGCAGCAVV Direction: Forward Position #: 3 Overlap #: 8 Alignment: --KGAGGBKG------- CDCCWGGTGGCAGCAVV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asyAGrkGGCRGCAga Reverse Complement Reverse Complement BVTGCTGCCVCCTSBDG HBTGCTGCCYMCTKST HVTGCTGCCHCCTBSTG Direction: Forward Position #: 1 Overlap #: 16 Alignment: BVTGCTGCCVCCTSBDG HBTGCTGCCYMCTKST- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif csCsCCTCCcc Original Motif Original Motif HVTGCTGCCHCCTBSTG VBCCCCTCCHB BBYSCYKCCHCCTBSTG Direction: Forward Position #: 1 Overlap #: 11 Alignment: HVTGCTGCCHCCTBSTG VBCCCCTCCHB------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 12 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 12 Motif 9 Reverse Complement Reverse Complement GAGCCATC SWGCCACC GAGCCAYC Direction: Forward Position #: 1 Overlap #: 8 Alignment: GAGCCATC SWGCCACC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asmAGRGGGCrCTGsmkc Original Motif Reverse Complement GAGCCAYC DBTSCAGMGCCCTCTRST GHKCCABCGCCCTCTRST Direction: Forward Position #: 1 Overlap #: 8 Alignment: GAGCCAYC---------- DBTSCAGMGCCCTCTRST ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif myrGYGCCmCCTast Reverse Complement Reverse Complement ASMAGAGGGCGBTGGYHC ASTAGGYGGCGCTBB ASHAGRKGGCGCTGBYHC Direction: Forward Position #: 1 Overlap #: 15 Alignment: ASMAGAGGGCGBTGGYHC ASTAGGYGGCGCTBB--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif gwGGCCAGmAGAGGGCrby Reverse Complement Original Motif GHKBCAGCGCCYMCTHST VHGGCCAGMAGAGGGCRBY VHGGCCAGMAGRGGGCASCGCCYMCTHST Direction: Forward Position #: 12 Overlap #: 8 Alignment: -----------GHKBCAGCGCCYMCTHST VHGGCCAGMAGAGGGCRBY---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wgGCCAshAGrGGGCrsy Original Motif Reverse Complement VHGGCCAGMAGRGGGCASCGCCYMCTHST KBKGCCCKCTHGTGGCHH DDKGCCMKCWGGKGGCVBCGCCYMCTHST Direction: Forward Position #: 1 Overlap #: 18 Alignment: VHGGCCAGMAGRGGGCASCGCCYMCTHST KBKGCCCKCTHGTGGCHH----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 13 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 13 Motif 47 Reverse Complement Reverse Complement GGDKCTG GGDKCTG GGDKCTG Direction: Backward Position #: 1 Overlap #: 7 Alignment: GGDKCTG GGDKCTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 53 Reverse Complement Original Motif CAGYDCC CAGATCCC CAGMTCCC Direction: Forward Position #: 1 Overlap #: 7 Alignment: CAGYDCC- CAGATCCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Original Motif Original Motif CAGMTCCC TTCAGCACCATGGACAGCKCC TTCAGHACCMTGGACAGCKCC Direction: Forward Position #: 3 Overlap #: 8 Alignment: --CAGMTCCC----------- TTCAGCACCATGGACAGCKCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 22 Reverse Complement Reverse Complement GGYGCTGTCCARGGTDCTGAA GGKATCTG GGGAKCTGTCCARGGTDCTGAA Direction: Forward Position #: 2 Overlap #: 7 Alignment: -GGYGCTGTCCARGGTDCTGAA GGKATCTG-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asmAGRGGGCrCTGsmkc Reverse Complement Reverse Complement TTCAGHACCMTGGACAGRTCCC DBTSCAGMGCCCTCTRST DBTBCAGMRCCCTSKACWGRTCCC Direction: Forward Position #: 3 Overlap #: 16 Alignment: --TTCAGHACCMTGGACAGRTCCC DBTSCAGMGCCCTCTRST------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 14 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 14 Motif 57 Original Motif Reverse Complement TSTGTR KTGTGTGT TTGTGTGK Direction: Backward Position #: 2 Overlap #: 6 Alignment: -TSTGTR- KTGTGTGT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 3 Reverse Complement Original Motif YCACACAA CACACACA CMCACACAA Direction: Forward Position #: 2 Overlap #: 7 Alignment: -YCACACAA CACACACA- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif dwCAGAAGwh Reverse Complement Reverse Complement TTGTGTGYG HDCTTCTGHD HDCTTSTGTDYG Direction: Forward Position #: 4 Overlap #: 7 Alignment: ---TTGTGTGYG HDCTTCTGHD-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RUNX1 Original Motif Original Motif HDCTTSTGTDYG BBYTGTGGTTT BDCTKYKGTBTG Direction: Forward Position #: 1 Overlap #: 11 Alignment: HDCTTSTGTDYG BBYTGTGGTTT- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 24 Combined Motif Original Motif Original Motif BDCTKYKGTBTG TGTGGGTG GTGTGGKTDBDC Direction: Backward Position #: 2 Overlap #: 8 Alignment: BDCTKYKGTBTG ---TGTGGGTG- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 15 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 15 kkAAGAGCAsy Reverse Complement Original Motif TTAAGAGC DBAAGAGCAVH TTAAGAGCAVH Direction: Forward Position #: 1 Overlap #: 8 Alignment: TTAAGAGC--- DBAAGAGCAVH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 55 Original Motif Reverse Complement TTAAGAGCAVH TTGTGAGC TTRWGAGCAVH Direction: Forward Position #: 1 Overlap #: 8 Alignment: TTAAGAGCAVH TTGTGAGC--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTwAAAAww Reverse Complement Reverse Complement HVTGCTCWKAA HHTTTTWADD HHTKYTMADAA Direction: Forward Position #: 1 Overlap #: 10 Alignment: HVTGCTCWKAA HHTTTTWADD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif T Reverse Complement Original Motif TTDTRAMYADH CTAGGTGTGAA CTAGGTGTBAWRAMYADH Direction: Forward Position #: 8 Overlap #: 4 Alignment: -------TTDTRAMYADH CTAGGTGTGAA------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 16 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 16 GABPA Reverse Complement Reverse Complement MMCTTCC VVCACTTCCGG GGMMCTTCCVV Direction: Backward Position #: 3 Overlap #: 7 Alignment: --MMCTTCC-- VVCACTTCCGG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 17 Reverse Complement Reverse Complement VVGGAAGYRCC GGAGGDGG GGAGGARGYRCC Direction: Forward Position #: 2 Overlap #: 7 Alignment: -VVGGAAGYRCC GGAGGDGG---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif dwCAGAAGwh Original Motif Original Motif GGAGGARGYRCC DHCAGAAGDH GVMRGAAGHDCC Direction: Forward Position #: 1 Overlap #: 10 Alignment: GGAGGARGYRCC DHCAGAAGDH-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RELA Reverse Complement Reverse Complement GGHHCTTCKRVC GGAAATKCCC GGAAMTTCBVVC Direction: Forward Position #: 1 Overlap #: 10 Alignment: GGHHCTTCKRVC GGAAATKCCC-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif csCsCCTCCcc Original Motif Original Motif GGAAMTTCBVVC VBCCCCTCCHB GGCMCYTCCBVC Direction: Forward Position #: 1 Overlap #: 11 Alignment: GGAAMTTCBVVC VBCCCCTCCHB- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 17 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 17 csCsCCTCCcc Reverse Complement Reverse Complement GGAGGDGG BDGGAGGGGBV VGGAGGDGGBD Direction: Backward Position #: 2 Overlap #: 8 Alignment: --GGAGGDGG- BDGGAGGGGBV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 11 Reverse Complement Original Motif HBCCHCCTCCV CTBCCTCY CTSCCYCTCCV Direction: Forward Position #: 1 Overlap #: 8 Alignment: HBCCHCCTCCV CTBCCTCY--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- csCSCCdCCCcs Combined Motif Original Motif Original Motif CTSCCYCTCCV VBCCCCDCCCHV CBBCCCCTCCCHV Direction: Forward Position #: 2 Overlap #: 10 Alignment: CTSCCYCTCCV-- -VBCCCCDCCCHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 27 Reverse Complement Reverse Complement VDGGGAGGGGBVG GGCGGCSG GGSGGCGGGGBVG Direction: Forward Position #: 1 Overlap #: 8 Alignment: VDGGGAGGGGBVG GGCGGCSG----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif SP1 Original Motif Reverse Complement GGSGGCGGGGBVG GGGGGYGGGG GGSGGHGGGGBVG Direction: Forward Position #: 1 Overlap #: 10 Alignment: GGSGGCGGGGBVG GGGGGYGGGG--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 18 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 18 yrCATGCAyr Original Motif Reverse Complement CATGYATG HVTGCATGKV KVCATGCATG Direction: Backward Position #: 3 Overlap #: 8 Alignment: CATGYATG-- HVTGCATGKV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 31 Reverse Complement Original Motif CATGCATGBR CATGYACA CATGCAYRBR Direction: Forward Position #: 1 Overlap #: 8 Alignment: CATGCATGBR CATGYACA-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TP53 Original Motif Reverse Complement CATGCAYRBR ACATGCCCGGKCATGTCCSR ACATGCMCGGDCATGTCCSR Direction: Forward Position #: 2 Overlap #: 10 Alignment: -CATGCAYRBR--------- ACATGCCCGGKCATGTCCSR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif SRF Original Motif Reverse Complement ACATGCMCGGDCATGTCCSR CCATATATGGGC MCATRYAYGGGCATGTCCSR Direction: Forward Position #: 1 Overlap #: 12 Alignment: ACATGCMCGGDCATGTCCSR CCATATATGGGC-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif znf143 Original Motif Original Motif MCATRYAYGGGCATGTCCSR BAHYTCCCAKMATGCMWYGC BAHYTCCCAKMATGCCWTRYAYGGGCATGTCCSR Direction: Forward Position #: 15 Overlap #: 6 Alignment: --------------MCATRYAYGGGCATGTCCSR BAHYTCCCAKMATGCMWYGC-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 19 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 19 Motif 33 Original Motif Reverse Complement CAGSCAG GWAGCCAG MAGCCAGG Direction: Backward Position #: 1 Overlap #: 7 Alignment: -CAGSCAG GWAGCCAG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 28 Original Motif Reverse Complement MAGCCAGG CAGGAAG CAGSMAGG Direction: Forward Position #: 1 Overlap #: 7 Alignment: MAGCCAGG CAGGAAG- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 11 Original Motif Reverse Complement CAGSMAGG MGAGGBAG MSAGGVAGG Direction: Forward Position #: 2 Overlap #: 7 Alignment: -CAGSMAGG MGAGGBAG- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 10 Reverse Complement Original Motif CCTVCCTSY CTGGCCTC CYKGCCTCY Direction: Forward Position #: 1 Overlap #: 8 Alignment: CCTVCCTSY CTGGCCTC- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 25 Original Motif Original Motif CYKGCCTCY CTGRGTTC CTGRSYTCY Direction: Forward Position #: 1 Overlap #: 8 Alignment: CYKGCCTCY CTGRGTTC- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 20 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 20 Arnt Original Motif Reverse Complement CACGTR CACGTG CACGTG Direction: Forward Position #: 1 Overlap #: 6 Alignment: CACGTR CACGTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif MYCMAX Original Motif Reverse Complement CACGTG ACCACGTGSTM ACCACGTGSTM Direction: Forward Position #: 3 Overlap #: 6 Alignment: --CACGTG--- ACCACGTGSTM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif MAX Reverse Complement Original Motif RASCACGTGGT DAHCACGTGD DAVCACGTGGT Direction: Forward Position #: 1 Overlap #: 10 Alignment: RASCACGTGGT DAHCACGTGD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- USF1 Combined Motif Reverse Complement Reverse Complement ACCACGTGVTH MCACGTG ACCACGTGVTH Direction: Forward Position #: 2 Overlap #: 7 Alignment: ACCACGTGVTH -MCACGTG--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Myc Original Motif Reverse Complement ACCACGTGVTH DCCACGTGCV DCCACGTGVDH Direction: Forward Position #: 1 Overlap #: 10 Alignment: ACCACGTGVTH DCCACGTGCV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 21 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 21 Motif 48 Original Motif Original Motif CCACYAGG CCACYAGR CCACYAGG Direction: Backward Position #: 1 Overlap #: 8 Alignment: CCACYAGG CCACYAGR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif grCCACyAGAkG Original Motif Original Motif CCACYAGG DDCCACYAGAKG DDCCACYAGRKG Direction: Forward Position #: 3 Overlap #: 8 Alignment: --CCACYAGG-- DDCCACYAGAKG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif grCCACwAGrk Original Motif Original Motif DDCCACYAGRKG DDCCACWAGRK DDCCACYAGRKG Direction: Forward Position #: 1 Overlap #: 11 Alignment: DDCCACYAGRKG DDCCACWAGRK- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif grCCACyAGAkG Original Motif Original Motif DDCCACYAGRKG DDCCACYAGAKG DDCCACYAGAKG Direction: Forward Position #: 1 Overlap #: 12 Alignment: DDCCACYAGRKG DDCCACYAGAKG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Original Motif Original Motif DDCCACYAGAKG YDRCCASYAGRKGGCRSYV YDDCCACYAGRKGGCRSYV Direction: Forward Position #: 2 Overlap #: 12 Alignment: -DDCCACYAGAKG------ YDRCCASYAGRKGGCRSYV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 22 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 22 Motif 53 Reverse Complement Reverse Complement GGKATCTG GGGATCTG GGGATCTG Direction: Forward Position #: 1 Overlap #: 8 Alignment: GGKATCTG GGGATCTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 69 Original Motif Original Motif GGGATCTG CCTGGARCTGGAGT CCKGGAKCTGGAGT Direction: Forward Position #: 3 Overlap #: 8 Alignment: --GGGATCTG---- CCTGGARCTGGAGT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asmAGRGGGCrCTGsmkc Reverse Complement Reverse Complement ACTCCAGRTCCYGG DBTSCAGMGCCCTCTRST DCTCCAGVKCCCKSTRST Direction: Forward Position #: 1 Overlap #: 14 Alignment: ACTCCAGRTCCYGG---- DBTSCAGMGCCCTCTRST ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 64 Combined Motif Reverse Complement Reverse Complement ASMASYGGGYBCTGGAGD TGMATATG ASMASYGGGYBCTGSATATG Direction: Forward Position #: 13 Overlap #: 6 Alignment: ASMASYGGGYBCTGGAGD-- ------------TGMATATG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- brCAGGGCCrs Combined Motif Reverse Complement Original Motif CATATSCAGVKCCCKSTRST BVCAGGGCCVB CATATVCAGDGCCHBSTRST Direction: Forward Position #: 5 Overlap #: 11 Alignment: CATATSCAGVKCCCKSTRST ----BVCAGGGCCVB----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 23 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 23 REST Original Motif Original Motif GASAGAGA TTCAGCACCATGGACAGCKCC TTCAGCACCATGGASAGMGMC Direction: Forward Position #: 13 Overlap #: 8 Alignment: ------------GASAGAGA- TTCAGCACCATGGACAGCKCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 24 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 24 Motif 3 Reverse Complement Original Motif CACCCACA CACACACA CACMCACA Direction: Backward Position #: 1 Overlap #: 8 Alignment: CACCCACA CACACACA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccAsCCCCAcc Original Motif Original Motif CACMCACA HVASCCCCABH HCASCCMCABH Direction: Forward Position #: 2 Overlap #: 8 Alignment: -CACMCACA-- HVASCCCCABH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RUNX1 Original Motif Reverse Complement HCASCCMCABH AAACCACAKVB HMACCMCMRVB Direction: Forward Position #: 1 Overlap #: 11 Alignment: HCASCCMCABH AAACCACAKVB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 25 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 25 Motif 33 Original Motif Original Motif CTGRGTTC CTGGCTWC CTGGSTTC Direction: Forward Position #: 1 Overlap #: 8 Alignment: CTGRGTTC CTGGCTWC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 10 Reverse Complement Reverse Complement GAASCCAG GAGGCCAG GARGCCAG Direction: Forward Position #: 1 Overlap #: 8 Alignment: GAASCCAG GAGGCCAG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 49 Original Motif Reverse Complement GARGCCAG GAGGCCAG GAGGCCAG Direction: Forward Position #: 1 Overlap #: 8 Alignment: GARGCCAG GAGGCCAG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR2F1 Combined Motif Reverse Complement Original Motif CTGGCCTC TGAMCTTTGMMCYT CTGRCCTYTGMMCYT Direction: Forward Position #: 2 Overlap #: 7 Alignment: CTGGCCTC------- -TGAMCTTTGMMCYT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 37 Original Motif Original Motif CTGRCCTYTGMMCYT CTGAGCYA CTGASCYMTGMMCYT Direction: Forward Position #: 1 Overlap #: 8 Alignment: CTGRCCTYTGMMCYT CTGAGCYA------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 26 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 26 dwCAGAAGwh Original Motif Original Motif CAGAGGAY DHCAGAAGDH DHCAGARGAY Direction: Forward Position #: 3 Overlap #: 8 Alignment: --CAGAGGAY DHCAGAAGDH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CasCAGrGGGCrsy Original Motif Original Motif DHCAGARGAY CACCAGRGGGCRSB CDVCAGAGGRCRSB Direction: Forward Position #: 2 Overlap #: 10 Alignment: -DHCAGARGAY--- CACCAGRGGGCRSB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- AgmAGAGGGCrscAGak Combined Motif Original Motif Original Motif CDVCAGAGGRCRSB AGMAGAGGGCASCAGAK CAVCAGAGGGCRSYAGAK Direction: Forward Position #: 2 Overlap #: 13 Alignment: CDVCAGAGGRCRSB---- -AGMAGAGGGCASCAGAK ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yrcrGYGCCMyCTGGtG Original Motif Reverse Complement CAVCAGAGGGCRSYAGAK CACCAGMGGGCGCTGBD CASCAGAGGGCRCBRGDK Direction: Forward Position #: 1 Overlap #: 17 Alignment: CAVCAGAGGGCRSYAGAK CACCAGMGGGCGCTGBD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asmAGRGGGCrCTGsmkc Reverse Complement Reverse Complement RDCKVGMGCCCTCTGSTG DBTSCAGMGCCCTCTRST DVTSBAGMGCCCTCTRSTG Direction: Forward Position #: 2 Overlap #: 17 Alignment: -RDCKVGMGCCCTCTGSTG DBTSCAGMGCCCTCTRST- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 27 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 27 ctCTrsyGCCmCCTast Reverse Complement Reverse Complement GGCGGCSG ASTAGGYGGCMSCAGDD ASTAGGCGGCVGCAGDD Direction: Forward Position #: 5 Overlap #: 8 Alignment: ----GGCGGCSG----- ASTAGGYGGCMSCAGDD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yvTGCyGCCmCCwGgtG Original Motif Reverse Complement ASTAGGCGGCVGCAGDD CDCCWGGTGGCAGCAVV CACYAGGYGGCMGCAGVD Direction: Forward Position #: 2 Overlap #: 16 Alignment: -ASTAGGCGGCVGCAGDD CDCCWGGTGGCAGCAVV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 17 Combined Motif Original Motif Reverse Complement CACYAGGYGGCMGCAGVD GGAGGDGG CAGGAGGHGGCMGCAGVD Direction: Forward Position #: 3 Overlap #: 8 Alignment: CACYAGGYGGCMGCAGVD --GGAGGDGG-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif myrGYGCCmCCTast Reverse Complement Reverse Complement HBCTGCYGCCHCCTCCTG ASTAGGYGGCGCTBB HBBWGSYGSCDCYTBCTG Direction: Forward Position #: 1 Overlap #: 15 Alignment: HBCTGCYGCCHCCTCCTG ASTAGGYGGCGCTBB--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGGCCGss Original Motif Reverse Complement HBBWGSYGSCDCYTBCTG VSCGGCCGSB VBCGGCCGSCDCYTBCTG Direction: Forward Position #: 1 Overlap #: 10 Alignment: HBBWGSYGSCDCYTBCTG VSCGGCCGSB-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 28 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 28 Stat3 Reverse Complement Original Motif CAGGAAG TTCCAGGAAG TTCCAGGAAG Direction: Forward Position #: 4 Overlap #: 7 Alignment: ---CAGGAAG TTCCAGGAAG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif GABPA Reverse Complement Reverse Complement CTTCCTGGAA VVCACTTCCGG VVCACTTCCKGGAA Direction: Forward Position #: 5 Overlap #: 7 Alignment: ----CTTCCTGGAA VVCACTTCCGG--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ELK4 Reverse Complement Reverse Complement TTCCYGGAAGTGVV ACTTCCGGT AYTYCCGGWAGTGVV Direction: Forward Position #: 2 Overlap #: 8 Alignment: -TTCCYGGAAGTGVV ACTTCCGGT------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ELK1 Original Motif Reverse Complement AYTYCCGGWAGTGVV MTTCCGGHBV MTTCCSGGDAGTGVV Direction: Forward Position #: 1 Overlap #: 10 Alignment: AYTYCCGGWAGTGVV MTTCCGGHBV----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 19 Original Motif Reverse Complement MTTCCSGGDAGTGVV CTGSCTG TGCWGBSMTTCCSGGDA Direction: Backward Position #: 3 Overlap #: 5 Alignment: MTTCCSGGDAGTGVV-- ----------CTGSCTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 29 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 29 mkCTyTTCsg Reverse Complement Reverse Complement MGAAATG HBGAAAAGBD BDMGAAAWGH Direction: Backward Position #: 3 Overlap #: 7 Alignment: -MGAAATG-- HBGAAAAGBD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 66 Combined Motif Original Motif Original Motif BDMGAAAWGH TATAAATR BTAKAAATGH Direction: Forward Position #: 2 Overlap #: 8 Alignment: BDMGAAAWGH -TATAAATR- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TP53 Original Motif Original Motif BTAKAAATGH MSGGACATGYCCGGGCATGT HBRGAMATGYCCGGGCATGT Direction: Forward Position #: 1 Overlap #: 10 Alignment: BTAKAAATGH---------- MSGGACATGYCCGGGCATGT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RELA Combined Motif Original Motif Original Motif HBRGAMATGYCCGGGCATGT GGGRATTTCC HBGGAMWTKCCCGGGCATGT Direction: Forward Position #: 2 Overlap #: 10 Alignment: HBRGAMATGYCCGGGCATGT -GGGRATTTCC--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif GABPA Original Motif Original Motif HBGGAMWTKCCCGGGCATGT CCGGAAGTGVV CCGGAARTKCCCGGGCATGT Direction: Forward Position #: 1 Overlap #: 11 Alignment: HBGGAMWTKCCCGGGCATGT CCGGAAGTGVV--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 30 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 30 Myf Reverse Complement Original Motif GCTGCWG MRGCARCWGSWG GCTGCWGMRGCA Direction: Backward Position #: 1 Overlap #: 7 Alignment: -----GCTGCWG MRGCARCWGSWG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 41 Original Motif Original Motif GCTGCWGMRGCA CCTGCTGK SCTGCTGVRGCA Direction: Forward Position #: 1 Overlap #: 8 Alignment: GCTGCWGMRGCA CCTGCTGK---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NHLH1 Original Motif Reverse Complement SCTGCTGVRGCA VCGCAGCTGCGV VCSCWGCTGBRVCA Direction: Forward Position #: 3 Overlap #: 10 Alignment: --SCTGCTGVRGCA VCGCAGCTGCGV-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 27 Original Motif Original Motif VCSCWGCTGBRVCA CSGCCGCC CCGCMGCYGBRVCA Direction: Forward Position #: 1 Overlap #: 8 Alignment: VCSCWGCTGBRVCA CSGCCGCC------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif agrCCAGmAGrg Original Motif Original Motif CCGCMGCYGBRVCA HVGCCAGMAGRG HVSSCAGCHGVGVCA Direction: Forward Position #: 2 Overlap #: 11 Alignment: -CCGCMGCYGBRVCA HVGCCAGMAGRG--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 31 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 31 TP53 Reverse Complement Reverse Complement TGTKCATG ACATGCCCGGKCATGTCCSR ACATGCCYGKKCATGTCCSR Direction: Forward Position #: 8 Overlap #: 8 Alignment: -------TGTKCATG----- ACATGCCCGGKCATGTCCSR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yrCATGCAyr Original Motif Original Motif ACATGCCYGKKCATGTCCSR BRCATGCABD BACATGCMYGKKCATGTCCSR Direction: Forward Position #: 2 Overlap #: 9 Alignment: -ACATGCCYGKKCATGTCCSR BRCATGCABD----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 18 Combined Motif Reverse Complement Reverse Complement MSGGACATGYRCMYGCATGTV CATKCATG MCRKRCATGYRCMYGCATGTV Direction: Forward Position #: 2 Overlap #: 8 Alignment: MSGGACATGYRCMYGCATGTV -CATKCATG------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 64 Reverse Complement Original Motif BACATGCMYGKKCATGKRKGR CATATRCA CAYATGCAYGKKCATGKRKGR Direction: Forward Position #: 1 Overlap #: 8 Alignment: BACATGCMYGKKCATGKRKGR CATATRCA------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Original Motif Reverse Complement CAYATGCAYGKKCATGKRKGR GGYGCTGTCCATGGTGCTGAA GGYBMTRTSCATGGTSMTGDRKGR Direction: Forward Position #: 4 Overlap #: 18 Alignment: ---CAYATGCAYGKKCATGKRKGR GGYGCTGTCCATGGTGCTGAA--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 32 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 32 Motif 52 Reverse Complement Reverse Complement TTTATTY WTTTATTT WTTTATTT Direction: Forward Position #: 2 Overlap #: 7 Alignment: -TTTATTY WTTTATTT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 2 Reverse Complement Original Motif AAATAAAW AAAAHAAA AAAWAAAA Direction: Forward Position #: 1 Overlap #: 8 Alignment: AAATAAAW AAAAHAAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 68 Original Motif Original Motif AAAWAAAA WAAWAAAWAWWWAA AAAWAAAWAWWWAA Direction: Forward Position #: 1 Overlap #: 8 Alignment: AAAWAAAA------ WAAWAAAWAWWWAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif waATwAAAATAww Original Motif Original Motif AAAWAAAWAWWWAA DHATWAAAATAHD WAATAAAAAWAWAA Direction: Forward Position #: 1 Overlap #: 13 Alignment: AAAWAAAWAWWWAA DHATWAAAATAHD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTwAAAAww Original Motif Original Motif WAATAAAAAWAWAA DDTWAAAAHH DWWTAAAAAWAWAA Direction: Forward Position #: 1 Overlap #: 10 Alignment: WAATAAAAAWAWAA DDTWAAAAHH---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 33 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 33 Motif 49 Original Motif Original Motif CTGGCTWC CTGGCCTC CTGGCYTC Direction: Backward Position #: 1 Overlap #: 8 Alignment: CTGGCTWC CTGGCCTC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 10 Original Motif Original Motif CTGGCYTC CTGGCCTC CTGGCCTC Direction: Forward Position #: 1 Overlap #: 8 Alignment: CTGGCYTC CTGGCCTC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 25 Original Motif Original Motif CTGGCCTC CTGRGTTC CTGRSYTC Direction: Forward Position #: 1 Overlap #: 8 Alignment: CTGGCCTC CTGRGTTC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif gwGGCCAGmAGAGGGCrby Reverse Complement Original Motif GAMSMCAG VHGGCCAGMAGAGGGCRBY GAVGCCAGMAGAGGGCRBY Direction: Forward Position #: 1 Overlap #: 8 Alignment: GAMSMCAG----------- VHGGCCAGMAGAGGGCRBY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif shAGrGGGCAgy Reverse Complement Reverse Complement KBKGCCCTCTYCTGGCBTC DBTGCCCKCTDS DBTGCCCTCTHCTGGCBTC Direction: Forward Position #: 1 Overlap #: 12 Alignment: KBKGCCCTCTYCTGGCBTC DBTGCCCKCTDS------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 34 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 34 ysGTGGCCACsr Original Motif Reverse Complement TGKCCACA VBGTGGCCACVB BTGGCCACAVBG Direction: Backward Position #: 2 Overlap #: 8 Alignment: ---TGKCCACA- VBGTGGCCACVB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RUNX1 Reverse Complement Original Motif CBVTGTGGCCAB BBYTGTGGTTT CBBTGTGGYYAB Direction: Forward Position #: 1 Overlap #: 11 Alignment: CBVTGTGGCCAB BBYTGTGGTTT- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wgGCCAshAGrGGGCrsy Reverse Complement Reverse Complement BTKKCCACABVG KBKGCCCKCTHGTGGCHH BBKGCCMYMTHGTGGCHH Direction: Forward Position #: 1 Overlap #: 12 Alignment: BTKKCCACABVG------ KBKGCCCKCTHGTGGCHH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 24 Reverse Complement Reverse Complement HDGCCACHARKYGGCYVB CACCCACA MASCCACAARKYGGCYVB Direction: Forward Position #: 1 Overlap #: 8 Alignment: HDGCCACHARKYGGCYVB CACCCACA---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Original Motif Original Motif MASCCACAARKYGGCYVB YDRCCASYAGRKGGCRSYV HDVCCACHAGGBGGCBVHV Direction: Forward Position #: 1 Overlap #: 18 Alignment: MASCCACAARKYGGCYVB- YDRCCASYAGRKGGCRSYV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 35 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 35 Motif 57 Original Motif Original Motif ACAACCAY ACACACAY ACAMMCAY Direction: Backward Position #: 1 Overlap #: 8 Alignment: ACAACCAY ACACACAY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Reverse Complement Reverse Complement KTGYYTGT GGYGCTGTCCATGGTGCTGAA GKGBCTGTCCATGGTGCTGAA Direction: Forward Position #: 1 Overlap #: 8 Alignment: KTGYYTGT------------- GGYGCTGTCCATGGTGCTGAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- T Combined Motif Reverse Complement Reverse Complement TTCAGCACCATGGACAGBCRC TTCACACCTAG TTYMRCACCTWGGACAGBCRC Direction: Forward Position #: 2 Overlap #: 11 Alignment: TTCAGCACCATGGACAGBCRC -TTCACACCTAG--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ccAsCCCCAcc Combined Motif Original Motif Original Motif TTYMRCACCTWGGACAGBCRC HVASCCCCABH THYAGCMCCAHGGACAGBCRC Direction: Forward Position #: 2 Overlap #: 11 Alignment: TTYMRCACCTWGGACAGBCRC -HVASCCCCABH--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- yrCATGCAyr Combined Motif Reverse Complement Original Motif GKGBCTGTCCHTGGRGCTKHA BRCATGCABD GTDCMTGYMBDTGGRGCTKHA Direction: Forward Position #: 2 Overlap #: 10 Alignment: GKGBCTGTCCHTGGRGCTKHA -BRCATGCABD---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 36 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 36 Stat3 Original Motif Reverse Complement TCCTGGRA CTTCCTGGAA CTTCCTGGRA Direction: Forward Position #: 3 Overlap #: 8 Alignment: --TCCTGGRA CTTCCTGGAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif agrCCAGmAGrg Reverse Complement Original Motif TKCCAGGAAG HVGCCAGMAGRG HTKCCAGSARRG Direction: Forward Position #: 2 Overlap #: 10 Alignment: -TKCCAGGAAG- HVGCCAGMAGRG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif znf143 Reverse Complement Original Motif CMMTSCTGGYAH BAHYTCCCAKMATGCMWYGC BMHHTCCYRGHATGCMWYGC Direction: Forward Position #: 2 Overlap #: 12 Alignment: -CMMTSCTGGYAH------- BAHYTCCCAKMATGCMWYGC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- gwGGCCAGmAGAGGGCrby Combined Motif Reverse Complement Original Motif GCMWRGCATDCMKGGADDRB VHGGCCAGMAGAGGGCRBY GCVWGGCMWGCAGRGRGCRBY Direction: Forward Position #: 3 Overlap #: 18 Alignment: GCMWRGCATDCMKGGADDRB- --VHGGCCAGMAGAGGGCRBY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Hand1Tcfe2a Original Motif Original Motif GCVWGGCMWGCAGRGRGCRBY BRTCTGGMWT BRYCTGGCHWGCAGRGRGCRBY Direction: Forward Position #: 2 Overlap #: 9 Alignment: -GCVWGGCMWGCAGRGRGCRBY BRTCTGGMWT------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 37 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 37 NFE2L2 Reverse Complement Original Motif TKGCTCAG RTGACWHAGCA CATGRCTCAGR Direction: Backward Position #: 3 Overlap #: 8 Alignment: -TKGCTCAG-- RTGACWHAGCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif brCAGGGCCrs Reverse Complement Original Motif KCTGAGKCATG BVCAGGGCCVB BDCWGRGBCABG Direction: Forward Position #: 2 Overlap #: 10 Alignment: -KCTGAGKCATG BVCAGGGCCVB- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ctCTTAACyw Original Motif Original Motif BDCWGRGBCABG HHCTTAACHD BBCTKARCCDBG Direction: Forward Position #: 1 Overlap #: 10 Alignment: BDCWGRGBCABG HHCTTAACHD-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 25 Combined Motif Original Motif Reverse Complement BBCTKARCCDBG GAACKCAG ARCCDBGCKCWGBBCTKAR Direction: Backward Position #: 8 Overlap #: 5 Alignment: ---BBCTKARCCDBG -------GAACKCAG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 38 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 38 Motif 51 Original Motif Original Motif GAGTTACA GAGTTACA GAGTTACA Direction: Backward Position #: 1 Overlap #: 8 Alignment: GAGTTACA GAGTTACA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 66 Original Motif Reverse Complement GAGTTACA KATTTATA GAKTTAYA Direction: Forward Position #: 1 Overlap #: 8 Alignment: GAGTTACA KATTTATA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Spz1 Original Motif Original Motif GAKTTAYA AGGGTAWCAGC AGRGTTACAGC Direction: Forward Position #: 2 Overlap #: 8 Alignment: -GAKTTAYA-- AGGGTAWCAGC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 69 Reverse Complement Original Motif GCTGTAACKCT CCTGGARCTGGAGT SCTGKAACTSKAGT Direction: Forward Position #: 1 Overlap #: 11 Alignment: GCTGTAACKCT--- CCTGGARCTGGAGT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Ddit3Cebpa Original Motif Original Motif SCTGKAACTSKAGT VDRTGCAATMCC VVVTGBAAYHSBAGT Direction: Forward Position #: 2 Overlap #: 11 Alignment: -SCTGKAACTSKAGT VDRTGCAATMCC--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 39 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 39 Motif 23 Original Motif Original Motif BAGAAA GASAGAGA GASAGARA Direction: Forward Position #: 3 Overlap #: 6 Alignment: --BAGAAA GASAGAGA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 45 Reverse Complement Reverse Complement TKTCTSTC TCTCTSC TYTCTSYC Direction: Forward Position #: 1 Overlap #: 7 Alignment: TKTCTSTC TCTCTSC- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- mkCTyTTCsg Combined Motif Original Motif Original Motif TYTCTSYC HBCTTTTCBD TBTCTYTYCBD Direction: Forward Position #: 2 Overlap #: 7 Alignment: TYTCTSYC--- -HBCTTTTCBD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 2 Original Motif Reverse Complement TBTCTYTYCBD TTTDTTTT TTTCTTTTCBD Direction: Forward Position #: 1 Overlap #: 8 Alignment: TBTCTYTYCBD TTTDTTTT--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif dwCAGAAGwh Reverse Complement Original Motif HBGAAAAGAAA DHCAGAAGDH HHSARAAGAHA Direction: Forward Position #: 1 Overlap #: 10 Alignment: HBGAAAAGAAA DHCAGAAGDH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 40 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 40 ccAsCCCCAcc Reverse Complement Reverse Complement CTGGGAMT DBTGGGGSTVD VDCTGGGRCTD Direction: Backward Position #: 3 Overlap #: 8 Alignment: -CTGGGAMT-- DBTGGGGSTVD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 69 Combined Motif Original Motif Original Motif VDCTGGGRCTD CCTGGARCTGGAGT VCCTGGRRCTGGAGT Direction: Forward Position #: 2 Overlap #: 10 Alignment: VDCTGGGRCTD---- -CCTGGARCTGGAGT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif znf143 Original Motif Reverse Complement VCCTGGRRCTGGAGT GCMWRGCATYRTGGGAMHTB GCMWRGCATBVYKGGRRMTBGAGT Direction: Forward Position #: 10 Overlap #: 11 Alignment: ---------VCCTGGRRCTGGAGT GCMWRGCATYRTGGGAMHTB---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TP53 Combined Motif Original Motif Original Motif GCMWRGCATBVYKGGRRMTBGAGT MSGGACATGYCCGGGCATGT GCVRRRCATGHCBGGRMATGKAGT Direction: Forward Position #: 2 Overlap #: 20 Alignment: GCMWRGCATBVYKGGRRMTBGAGT -MSGGACATGYCCGGGCATGT--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RUNX1 Original Motif Reverse Complement GCVRRRCATGHCBGGRMATGKAGT AAACCACAKVB RMMVSRCAKVBCBGGRMATGKAGT Direction: Forward Position #: 1 Overlap #: 11 Alignment: GCVRRRCATGHCBGGRMATGKAGT AAACCACAKVB------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 41 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 41 agrCCAGmAGrg Reverse Complement Original Motif YCAGCAGG HVGCCAGMAGRG HVGCCAGCAGGG Direction: Forward Position #: 4 Overlap #: 8 Alignment: ---YCAGCAGG- HVGCCAGMAGRG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yrcrGYGCCMyCTGGtG Reverse Complement Reverse Complement CCCTGCTGGCVH CACCAGMGGGCGCTGBD CMCCWGCKGGCBCTGBD Direction: Forward Position #: 2 Overlap #: 12 Alignment: -CCCTGCTGGCVH---- CACCAGMGGGCGCTGBD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 21 Original Motif Original Motif CMCCWGCKGGCBCTGBD CCACYAGG CCACCAGSKGGCBCTGBD Direction: Forward Position #: 2 Overlap #: 7 Alignment: -CMCCWGCKGGCBCTGBD CCACYAGG---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CasCAGrGGGCrsy Reverse Complement Original Motif HVCAGBGCCRSCTGGTGG CACCAGRGGGCRSB CAVCMRRGGSCRSCTGGTGG Direction: Forward Position #: 3 Overlap #: 12 Alignment: --HVCAGBGCCRSCTGGTGG CACCAGRGGGCRSB------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- gwGGCCAGmAGAGGGCrby Combined Motif Original Motif Reverse Complement CAVCMRRGGSCRSCTGGTGG KBKGCCCTCTYCTGGCCHV CAVCMRRGGSCRSCTGGTGSCCTCTYCTGGCCHV Direction: Forward Position #: 16 Overlap #: 5 Alignment: CAVCMRRGGSCRSCTGGTGG-------------- ---------------KBKGCCCTCTYCTGGCCHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 42 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 42 ssCGCwGCGss Reverse Complement Original Motif CSGCGCG VSCGCDGCGSB VSCGCBGCGCG Direction: Forward Position #: 5 Overlap #: 7 Alignment: ----CSGCGCG VSCGCDGCGSB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGwGCGss Original Motif Reverse Complement VSCGCBGCGCG VBCGCWCGSB VBCGCHSSGSG Direction: Forward Position #: 1 Overlap #: 10 Alignment: VSCGCBGCGCG VBCGCWCGSB- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif myrGYGCCmCCTast Original Motif Original Motif VBCGCHSSGSG VBAGCGCCMCCTAST VBMGCGCCVCSTAST Direction: Forward Position #: 1 Overlap #: 11 Alignment: VBCGCHSSGSG---- VBAGCGCCMCCTAST ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yrcrGYGCCMyCTGGtG Original Motif Original Motif VBMGCGCCVCSTAST HVCAGCGCCCYCTGGTG HVBMGCGCCMYCTRGTG Direction: Forward Position #: 2 Overlap #: 15 Alignment: -VBMGCGCCVCSTAST- HVCAGCGCCCYCTGGTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGGCrsTGCrs Original Motif Reverse Complement HVBMGCGCCMYCTRGTG BVGCASMGCCVV BHGCAGCGCCVBCTRGTG Direction: Forward Position #: 2 Overlap #: 11 Alignment: -HVBMGCGCCMYCTRGTG BVGCASMGCCVV------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 43 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 43 T Original Motif Reverse Complement ACATYTA TTCACACCTAG TTCACAYCTAG Direction: Forward Position #: 4 Overlap #: 7 Alignment: ---ACATYTA- TTCACACCTAG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 58 Combined Motif Reverse Complement Original Motif CTAGKTGTGAA TACATGCA CTASDTGYRAA Direction: Forward Position #: 2 Overlap #: 8 Alignment: CTAGKTGTGAA -TACATGCA-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 64 Original Motif Reverse Complement CTASDTGYRAA TGMATATG TSYATATGYRAA Direction: Forward Position #: 2 Overlap #: 7 Alignment: -CTASDTGYRAA TGMATATG---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yrCATGCAyr Reverse Complement Reverse Complement TTKKCATATMSA HVTGCATGKV HTTGCATGTMSA Direction: Forward Position #: 1 Overlap #: 10 Alignment: TTKKCATATMSA HVTGCATGKV-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TAL1TCF3 Reverse Complement Reverse Complement TSYACATGCAAH ARCAGATGRTVD WGCAVATGVWVH Direction: Forward Position #: 1 Overlap #: 12 Alignment: TSYACATGCAAH ARCAGATGRTVD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 44 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 44 raCAAAACam Reverse Complement Reverse Complement TGTTTDC HTGTTTTGTD TDTGTTTTSH Direction: Backward Position #: 3 Overlap #: 7 Alignment: -TGTTTDC-- HTGTTTTGTD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 68 Reverse Complement Original Motif HSAAAACADA WAAWAAAWAWWWAA HVAAAAMAAAWWAA Direction: Forward Position #: 1 Overlap #: 10 Alignment: HSAAAACADA---- WAAWAAAWAWWWAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 45 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 45 vkCKCTkCGk Original Motif Reverse Complement GSAGAGA BCGYAGAGDV VGCAGAGABC Direction: Backward Position #: 2 Overlap #: 7 Alignment: --GSAGAGA- BCGYAGAGDV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 23 Original Motif Original Motif VGCAGAGABC GASAGAGA GRSAGAGABC Direction: Forward Position #: 1 Overlap #: 8 Alignment: VGCAGAGABC GASAGAGA-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif gwGGCCAGmAGAGGGCrby Reverse Complement Reverse Complement GBTCTCTSKC KBKGCCCTCTYCTGGCCHV KGKKCYCTCTYCTGGCCHV Direction: Forward Position #: 2 Overlap #: 10 Alignment: -GBTCTCTSKC-------- KBKGCCCTCTYCTGGCCHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- AgmAGAGGGCrscAGak Combined Motif Original Motif Reverse Complement KGKKCYCTCTYCTGGCCHV RTCTGSTGCCCTCTYCT CTGGCCHVKGCCCTCTCBYKGKKCYCT Direction: Backward Position #: 9 Overlap #: 11 Alignment: ------KGKKCYCTCTYCTGGCCHV --------RTCTGSTGCCCTCTYCT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 46 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 46 Motif 1 Original Motif Original Motif AGRKGGCR AGRKGGCR AGRKGGCR Direction: Forward Position #: 1 Overlap #: 8 Alignment: AGRKGGCR AGRKGGCR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asCAGrkGGCrsy Reverse Complement Reverse Complement KGCCYKCT BSKGCCCMCTGST BSKGCCYBCTGST Direction: Forward Position #: 3 Overlap #: 8 Alignment: --KGCCYKCT--- BSKGCCCMCTGST ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wgGCCAshAGrGGGCrsy Original Motif Reverse Complement BSKGCCYBCTGST KBKGCCCKCTHGTGGCHH BSKGCCCBCTBSTGGCHH Direction: Forward Position #: 1 Overlap #: 13 Alignment: BSKGCCYBCTGST----- KBKGCCCKCTHGTGGCHH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CasCAGrGGGCrsy Original Motif Reverse Complement BSKGCCCBCTBSTGGCHH BSKGCCCKCTGGTG BSKGCCCKCTGSTGGCHH Direction: Forward Position #: 1 Overlap #: 14 Alignment: BSKGCCCBCTBSTGGCHH BSKGCCCKCTGGTG---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif gwGGCCAGmAGAGGGCrby Original Motif Reverse Complement BSKGCCCKCTGSTGGCHH KBKGCCCTCTYCTGGCCHV KBKGCCCTCTBSTGGCCHV Direction: Forward Position #: 1 Overlap #: 18 Alignment: BSKGCCCKCTGSTGGCHH- KBKGCCCTCTYCTGGCCHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 47 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 47 Motif 13 Reverse Complement Reverse Complement GGDKCTG GGDKCTG GGDKCTG Direction: Backward Position #: 1 Overlap #: 7 Alignment: GGDKCTG GGDKCTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 53 Reverse Complement Original Motif CAGYDCC CAGATCCC CAGMTCCC Direction: Forward Position #: 1 Overlap #: 7 Alignment: CAGYDCC- CAGATCCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Original Motif Original Motif CAGMTCCC TTCAGCACCATGGACAGCKCC TTCAGHACCMTGGACAGCKCC Direction: Forward Position #: 3 Overlap #: 8 Alignment: --CAGMTCCC----------- TTCAGCACCATGGACAGCKCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 22 Reverse Complement Reverse Complement GGYGCTGTCCARGGTDCTGAA GGKATCTG GGGAKCTGTCCARGGTDCTGAA Direction: Forward Position #: 2 Overlap #: 7 Alignment: -GGYGCTGTCCARGGTDCTGAA GGKATCTG-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif brCAGGGCCrs Reverse Complement Original Motif TTCAGHACCMTGGACAGRTCCC BVCAGGGCCVB BBCAGBRCCVBGGACAGRTCCC Direction: Forward Position #: 1 Overlap #: 11 Alignment: TTCAGHACCMTGGACAGRTCCC BVCAGGGCCVB----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 48 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 48 Motif 21 Original Motif Original Motif CCACYAGR CCACYAGG CCACYAGG Direction: Backward Position #: 1 Overlap #: 8 Alignment: CCACYAGR CCACYAGG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif grCCACyAGAkG Original Motif Original Motif CCACYAGG DDCCACYAGAKG DDCCACYAGRKG Direction: Forward Position #: 3 Overlap #: 8 Alignment: --CCACYAGG-- DDCCACYAGAKG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif grCCACwAGrk Original Motif Original Motif DDCCACYAGRKG DDCCACWAGRK DDCCACYAGRKG Direction: Forward Position #: 1 Overlap #: 11 Alignment: DDCCACYAGRKG DDCCACWAGRK- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif grCCACyAGAkG Original Motif Original Motif DDCCACYAGRKG DDCCACYAGAKG DDCCACYAGAKG Direction: Forward Position #: 1 Overlap #: 12 Alignment: DDCCACYAGRKG DDCCACYAGAKG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Original Motif Original Motif DDCCACYAGAKG YDRCCASYAGRKGGCRSYV YDDCCACYAGRKGGCRSYV Direction: Forward Position #: 2 Overlap #: 12 Alignment: -DDCCACYAGAKG------ YDRCCASYAGRKGGCRSYV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 49 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 49 Motif 10 Original Motif Original Motif CTGGCCTC CTGGCCTC CTGGCCTC Direction: Backward Position #: 1 Overlap #: 8 Alignment: CTGGCCTC CTGGCCTC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 33 Original Motif Original Motif CTGGCCTC CTGGCTWC CTGGCYTC Direction: Forward Position #: 1 Overlap #: 8 Alignment: CTGGCCTC CTGGCTWC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif gwGGCCAGmAGAGGGCrby Reverse Complement Original Motif GAKGCCAG VHGGCCAGMAGAGGGCRBY GAKGCCAGMAGAGGGCRBY Direction: Forward Position #: 1 Overlap #: 8 Alignment: GAKGCCAG----------- VHGGCCAGMAGAGGGCRBY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ysGTGGCCACsr Reverse Complement Reverse Complement KBKGCCCTCTYCTGGCYTC VBGTGGCCACVB VBGTGSCCWCTBCTGGCYTC Direction: Forward Position #: 2 Overlap #: 11 Alignment: -KBKGCCCTCTYCTGGCYTC VBGTGGCCACVB-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif shAGrGGGCAgy Original Motif Original Motif VBGTGSCCWCTBCTGGCYTC SHAGRGGGCABH SHAGDGGSCACBBCTGGCYTC Direction: Forward Position #: 2 Overlap #: 11 Alignment: -VBGTGSCCWCTBCTGGCYTC SHAGRGGGCABH--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 50 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 50 Motif 7 Reverse Complement Reverse Complement TTMCT TTTMCT TTMCTT Direction: Backward Position #: 1 Overlap #: 5 Alignment: -TTMCT TTTMCT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 39 Reverse Complement Original Motif AAGRAA BAGAAA VAGAAA Direction: Forward Position #: 1 Overlap #: 6 Alignment: AAGRAA BAGAAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 28 Original Motif Reverse Complement VAGAAA CAGGAAG CAGRAAG Direction: Forward Position #: 1 Overlap #: 6 Alignment: VAGAAA- CAGGAAG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 29 Reverse Complement Original Motif CTTMCTG CATTTCY CMTTYCTG Direction: Forward Position #: 2 Overlap #: 6 Alignment: -CTTMCTG CATTTCY- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stat3 Combined Motif Original Motif Reverse Complement CMTTYCTG CTTCCTGGAA CMTTCCTGGAA Direction: Forward Position #: 2 Overlap #: 7 Alignment: CMTTYCTG--- -CTTCCTGGAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 51 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 51 Motif 38 Original Motif Original Motif GAGTTACA GAGTTACA GAGTTACA Direction: Forward Position #: 1 Overlap #: 8 Alignment: GAGTTACA GAGTTACA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 66 Original Motif Reverse Complement GAGTTACA KATTTATA GAKTTAYA Direction: Forward Position #: 1 Overlap #: 8 Alignment: GAGTTACA KATTTATA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Ddit3Cebpa Original Motif Reverse Complement GAKTTAYA GGRATTGCAKHB GGADTTRCAKHB Direction: Forward Position #: 2 Overlap #: 8 Alignment: -GAKTTAYA--- GGRATTGCAKHB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Spz1 Original Motif Original Motif GGADTTRCAKHB AGGGTAWCAGC RGRGTWRCAKCB Direction: Forward Position #: 1 Overlap #: 11 Alignment: GGADTTRCAKHB AGGGTAWCAGC- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RELA Original Motif Original Motif RGRGTWRCAKCB GGGRATTTCC GGGRRTTTCMKCB Direction: Forward Position #: 2 Overlap #: 9 Alignment: -RGRGTWRCAKCB GGGRATTTCC--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 52 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 52 Motif 68 Reverse Complement Reverse Complement WTTTATTT TTWWWTWTTTWTTW WTTTATTWTTWWWT Direction: Backward Position #: 1 Overlap #: 8 Alignment: ------WTTTATTT TTWWWTWTTTWTTW ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif waATwAAAATAww Reverse Complement Original Motif AWWWAAWAATAAAW DHATWAAAATAHD AWAWAAAAATAAAW Direction: Forward Position #: 1 Overlap #: 13 Alignment: AWWWAAWAATAAAW DHATWAAAATAHD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 2 Original Motif Original Motif AWAWAAAAATAAAW AAAAHAAA AAAAAAAAATAAAW Direction: Forward Position #: 1 Overlap #: 8 Alignment: AWAWAAAAATAAAW AAAAHAAA------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTwAAAAww Original Motif Original Motif AAAAAAAAATAAAW DDTWAAAAHH AWWWAAAAAWAAAW Direction: Forward Position #: 1 Overlap #: 10 Alignment: AAAAAAAAATAAAW DDTWAAAAHH---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtATTTTTAww Original Motif Reverse Complement AWWWAAAAAWAAAW WWTAAAAATAD WWTAAAAATWAAAW Direction: Forward Position #: 1 Overlap #: 11 Alignment: AWWWAAAAAWAAAW WWTAAAAATAD--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 53 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 53 Motif 22 Original Motif Original Motif CAGATCCC CAGATYCC CAGATCCC Direction: Backward Position #: 1 Overlap #: 8 Alignment: CAGATCCC CAGATYCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asmAGRGGGCrCTGsmkc Original Motif Original Motif CAGATCCC ASMAGAGGGCRCTGSABH ASCAGAKSSCRCTGSABH Direction: Forward Position #: 3 Overlap #: 8 Alignment: --CAGATCCC-------- ASMAGAGGGCRCTGSABH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif brCAGGGCCrs Original Motif Original Motif ASCAGAKSSCRCTGSABH BVCAGGGCCVB VVCAGRGCCCVCTGSABH Direction: Forward Position #: 1 Overlap #: 11 Alignment: ASCAGAKSSCRCTGSABH BVCAGGGCCVB------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 69 Original Motif Reverse Complement VVCAGRGCCCVCTGSABH ACTCCAGMTCCAGG ACDCCAGVKCCMGSTGSABH Direction: Forward Position #: 3 Overlap #: 12 Alignment: --VVCAGRGCCCVCTGSABH ACTCCAGMTCCAGG------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yrcrGYGCCMyCTGGtG Original Motif Original Motif ACDCCAGVKCCMGSTGSABH HVCAGCGCCCYCTGGTG HACDSCRSCBYCWGSTGSABH Direction: Forward Position #: 2 Overlap #: 16 Alignment: -ACDCCAGVKCCMGSTGSABH HVCAGCGCCCYCTGGTG---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 54 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 54 wtATTTTTAww Original Motif Original Motif ATTYY DTATTTTTAWW DTATTTTTAWW Direction: Forward Position #: 3 Overlap #: 5 Alignment: --ATTYY---- DTATTTTTAWW ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 29 Combined Motif Original Motif Original Motif DTATTTTTAWW CATTTCY DCATTTYTAWW Direction: Forward Position #: 2 Overlap #: 7 Alignment: DTATTTTTAWW -CATTTCY--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif waATwAAAATAww Reverse Complement Original Motif WWTAKAAATGD DHATWAAAATAHD DHWWDAAAWKAHD Direction: Forward Position #: 1 Overlap #: 11 Alignment: WWTAKAAATGD-- DHATWAAAATAHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTwAAAAww Original Motif Original Motif DHWWDAAAWKAHD DDTWAAAAHH DHTWAAAAWDAHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DHWWDAAAWKAHD DDTWAAAAHH--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif znf143 Original Motif Original Motif DHTWAAAAWDAHD BAHYTCCCAKMATGCMWYGC BAHTTHMMADVATDCMWYGC Direction: Forward Position #: 2 Overlap #: 13 Alignment: -DHTWAAAAWDAHD------ BAHYTCCCAKMATGCMWYGC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 55 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 55 Motif 15 Original Motif Original Motif GCTCACAA GCTCTTAA GCTCWYAA Direction: Backward Position #: 1 Overlap #: 8 Alignment: GCTCACAA GCTCTTAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 57 Reverse Complement Reverse Complement TTKWGAGC KTGTGTGT TTGTGWGY Direction: Forward Position #: 1 Overlap #: 8 Alignment: TTKWGAGC KTGTGTGT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif grCCACyAGAkG Reverse Complement Original Motif KCWCACAA DDCCACYAGAKG KBHCACMAGAKG Direction: Forward Position #: 1 Overlap #: 8 Alignment: KCWCACAA---- DDCCACYAGAKG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif grCCACwAGrk Original Motif Original Motif KBHCACMAGAKG DDCCACWAGRK DVCCACWAGAKG Direction: Forward Position #: 1 Overlap #: 11 Alignment: KBHCACMAGAKG DDCCACWAGRK- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 56 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 56 Motif 21 Reverse Complement Reverse Complement CCATGTGG CCTKGTGG CCWTGTGG Direction: Backward Position #: 1 Overlap #: 8 Alignment: CCATGTGG CCTKGTGG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 48 Original Motif Reverse Complement CCWTGTGG MCTKGTGG CCTKGTGG Direction: Forward Position #: 1 Overlap #: 8 Alignment: CCWTGTGG MCTKGTGG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif MYCMAX Reverse Complement Reverse Complement CCACRAGG ACCACGTGSTM ACCACGWGGTM Direction: Forward Position #: 2 Overlap #: 8 Alignment: -CCACRAGG-- ACCACGTGSTM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Mycn Original Motif Original Motif ACCACGWGGTM HSCACGTGGC MCCACGTGGYM Direction: Forward Position #: 1 Overlap #: 10 Alignment: ACCACGWGGTM HSCACGTGGC- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif grCCACwAGrk Original Motif Reverse Complement MCCACGTGGYM YMCTWGTGGHH HCCWMGTGGHH Direction: Forward Position #: 1 Overlap #: 11 Alignment: MCCACGTGGYM YMCTWGTGGHH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 57 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 57 Motif 35 Reverse Complement Reverse Complement KTGTGTGT KTGGTTGT KTGKKTGT Direction: Forward Position #: 1 Overlap #: 8 Alignment: KTGTGTGT KTGGTTGT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RUNX1 Combined Motif Reverse Complement Reverse Complement ACAYYCAY AAACCACAKVB AHAHCCACAKVB Direction: Forward Position #: 2 Overlap #: 7 Alignment: ACAYYCAY---- -AAACCACAKVB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- T Combined Motif Original Motif Reverse Complement AHAHCCACAKVB TTCACACCTAG AHATYCACACCTAG Direction: Forward Position #: 4 Overlap #: 9 Alignment: AHAHCCACAKVB-- ---TTCACACCTAG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 55 Combined Motif Original Motif Original Motif AHATYCACACCTAG GCTCACAA AHRCTCACAMCTAG Direction: Forward Position #: 3 Overlap #: 8 Alignment: AHATYCACACCTAG --GCTCACAA---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccAsCCCCAcc Original Motif Original Motif AHRCTCACAMCTAG HVASCCCCABH AHASYCMCAVCTAG Direction: Forward Position #: 1 Overlap #: 11 Alignment: AHRCTCACAMCTAG HVASCCCCABH--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 58 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 58 yrCATGCAyr Original Motif Original Motif TACATGCA BRCATGCABD BDTACATGCA Direction: Backward Position #: 3 Overlap #: 8 Alignment: TACATGCA-- BRCATGCABD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TP53 Original Motif Original Motif BDTACATGCA MSGGACATGYCCGGGCATGT MBGKACATGCMCGGGCATGT Direction: Forward Position #: 2 Overlap #: 10 Alignment: -BDTACATGCA--------- MSGGACATGYCCGGGCATGT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 64 Reverse Complement Original Motif ACATGCCCGYGCATGTYCBR CATATRCA CAYATGCMCGYGCATGTYCBR Direction: Forward Position #: 2 Overlap #: 7 Alignment: -ACATGCCCGYGCATGTYCBR CATATRCA------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 36 Combined Motif Reverse Complement Reverse Complement MBGKACATGCMCGYGCATMTG TMCCAGGA TMTGYMCSAGSAMBGKACATG Direction: Backward Position #: 5 Overlap #: 8 Alignment: MBGKACATGCMCGYGCATMTG ---------TMCCAGGA---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 59 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 59 Motif 5 Reverse Complement Reverse Complement GGGKGGGG GGGDGGGG GGGKGGGG Direction: Backward Position #: 1 Overlap #: 8 Alignment: GGGKGGGG GGGDGGGG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif csCSCCdCCCcs Original Motif Reverse Complement GGGKGGGG VDGGGDGGGGBV GGGGGGGGGGBV Direction: Forward Position #: 1 Overlap #: 8 Alignment: GGGKGGGG---- VDGGGDGGGGBV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Klf4 Reverse Complement Reverse Complement VBCCCCCCCCCC GCCYCMCCCD BCCCCCCCCCCC Direction: Forward Position #: 1 Overlap #: 10 Alignment: VBCCCCCCCCCC GCCYCMCCCD-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif SP1 Reverse Complement Reverse Complement GGGGGGGGGGGB GGGGGYGGGG GGGGGBGGGGGB Direction: Forward Position #: 1 Overlap #: 10 Alignment: GGGGGGGGGGGB GGGGGYGGGG-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif csCsCCTCCcc Reverse Complement Original Motif BCCCCCBCCCCC VBCCCCTCCHB VBCCCCYCCCBCC Direction: Forward Position #: 2 Overlap #: 10 Alignment: -BCCCCCBCCCCC VBCCCCTCCHB-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 60 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 60 Motif 6 Original Motif Original Motif CTGGAR CTGGRRA ACTGGAR Direction: Backward Position #: 2 Overlap #: 6 Alignment: CTGGAR- CTGGRRA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 69 Original Motif Original Motif ACTGGAR CCTGGARCTGGAGT MCTGGARCTGGAGT Direction: Forward Position #: 1 Overlap #: 7 Alignment: ACTGGAR------- CCTGGARCTGGAGT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 36 Original Motif Original Motif MCTGGARCTGGAGT TCCTGGRA TCCTGGRACTGGAGT Direction: Forward Position #: 2 Overlap #: 7 Alignment: -MCTGGARCTGGAGT TCCTGGRA------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif agrCCAGmAGrg Original Motif Reverse Complement TCCTGGRACTGGAGT CKCTRCTGGCVH YGSWRCTGGMSTTCC Direction: Backward Position #: 1 Overlap #: 12 Alignment: TCCTGGRACTGGAGT ---CKCTRCTGGCVH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 61 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 61 Motif 63 Reverse Complement Reverse Complement KCCATCT CWCCCTCT CTCCMTCT Direction: Forward Position #: 2 Overlap #: 7 Alignment: -KCCATCT CWCCCTCT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TAL1TCF3 Original Motif Original Motif CTCCMTCT HVAMCATCTGKT HCWCCATCTGKT Direction: Forward Position #: 2 Overlap #: 8 Alignment: -CTCCMTCT--- HVAMCATCTGKT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif gwGGCCAGmAGAGGGCrby Original Motif Reverse Complement HCWCCATCTGKT KBKGCCCTCTYCTGGCCHV KBBRCCMTCTGBTGGCCHV Direction: Forward Position #: 2 Overlap #: 12 Alignment: -HCWCCATCTGKT------ KBKGCCCTCTYCTGGCCHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 46 Reverse Complement Original Motif VHGGCCABCAGARGGMBBY AGRKGGCR AGRGGSCABCAGARGGMBBY Direction: Forward Position #: 2 Overlap #: 7 Alignment: -VHGGCCABCAGARGGMBBY AGRKGGCR------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 1 Original Motif Original Motif AGRGGSCABCAGARGGMBBY AGRKGGCR AGRGGGCRBCAGARGGMBBY Direction: Forward Position #: 1 Overlap #: 8 Alignment: AGRGGSCABCAGARGGMBBY AGRKGGCR------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 62 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 62 myrGYGCCmCCTast Original Motif Original Motif CGCCVCC VBAGCGCCMCCTAST TASTCGCCMCCVBAG Direction: Backward Position #: 5 Overlap #: 7 Alignment: ----CGCCVCC---- VBAGCGCCMCCTAST ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 27 Original Motif Original Motif TASTCGCCMCCVBAG CSGCCGCC YVGCCGCCMCCVBAG Direction: Forward Position #: 1 Overlap #: 8 Alignment: TASTCGCCMCCVBAG CSGCCGCC------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rgCGCCmyCTgs Reverse Complement Reverse Complement CTBBGGYGGCGGCVK SHAGKGGGCGCB SHMKKDGGCGGCGGCVK Direction: Forward Position #: 3 Overlap #: 10 Alignment: --CTBBGGYGGCGGCVK SHAGKGGGCGCB----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif scAGrkGGCGcy Original Motif Original Motif SHMKKDGGCGGCGGCVK SHAGRGGGCGCB SHAGDGGGCGSBGGCVK Direction: Forward Position #: 1 Overlap #: 12 Alignment: SHMKKDGGCGGCGGCVK SHAGRGGGCGCB----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif csCSCCdCCCcs Original Motif Reverse Complement SHAGDGGGCGSBGGCVK VDGGGDGGGGBV VVGRGDGGGSGVBGGCVK Direction: Forward Position #: 2 Overlap #: 11 Alignment: -SHAGDGGGCGSBGGCVK VDGGGDGGGGBV------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 63 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 63 Motif 11 Original Motif Reverse Complement AGAGGGWG MGAGGBAG AGAGGGAG Direction: Backward Position #: 1 Overlap #: 8 Alignment: AGAGGGWG MGAGGBAG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asmAGRGGGCrCTGsmkc Original Motif Original Motif AGAGGGAG ASMAGAGGGCRCTGSABH AGARGRRGGCRCTGSABH Direction: Forward Position #: 1 Overlap #: 8 Alignment: AGAGGGAG---------- ASMAGAGGGCRCTGSABH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif scAGrkGGCGcy Original Motif Original Motif AGARGRRGGCRCTGSABH SHAGRGGGCGCB SHAGARGGVGGCRCTGSABH Direction: Forward Position #: 3 Overlap #: 10 Alignment: --AGARGRRGGCRCTGSABH SHAGRGGGCGCB-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- gwGGCCAGmAGAGGGCrby Combined Motif Original Motif Reverse Complement SHAGARGGVGGCRCTGSABH KBKGCCCTCTYCTGGCCHV SHAGARGGVGGCGSTGCCCBCTYCTGGCCHV Direction: Forward Position #: 13 Overlap #: 8 Alignment: SHAGARGGVGGCRCTGSABH----------- ------------KBKGCCCTCTYCTGGCCHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rgCGCCmyCTgs Original Motif Reverse Complement SHAGARGGVGGCGSTGCCCBCTYCTGGCCHV SHAGKGGGCGCB SHAGDGGGCGSBGSTGCCCBCTYCTGGCCHV Direction: Forward Position #: 1 Overlap #: 12 Alignment: SHAGARGGVGGCGSTGCCCBCTYCTGGCCHV SHAGKGGGCGCB------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 64 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 64 Motif 31 Original Motif Original Motif CATATRCA CATGYACA CATRTACA Direction: Forward Position #: 1 Overlap #: 8 Alignment: CATATRCA CATGYACA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 3 Original Motif Original Motif CATRTACA CACACACA CAYAYACA Direction: Forward Position #: 1 Overlap #: 8 Alignment: CATRTACA CACACACA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 58 Original Motif Original Motif CAYAYACA TACATGCA YACATRCA Direction: Forward Position #: 1 Overlap #: 8 Alignment: CAYAYACA TACATGCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yrCATGCAyr Original Motif Original Motif YACATRCA BRCATGCABD YACATGCABD Direction: Forward Position #: 1 Overlap #: 8 Alignment: YACATRCA-- BRCATGCABD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 69 Reverse Complement Reverse Complement HVTGCATGTM ACTCCAGMTCCAGG AMTSCAKVTMCAGG Direction: Forward Position #: 1 Overlap #: 10 Alignment: HVTGCATGTM---- ACTCCAGMTCCAGG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 65 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 65 raCAAAACam Original Motif Original Motif ARAACA DACAAAACAH HAAAACADAC Direction: Backward Position #: 2 Overlap #: 6 Alignment: ---ARAACA- DACAAAACAH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 44 Original Motif Original Motif HAAAACADAC GDAAACA GAAAACADAC Direction: Forward Position #: 1 Overlap #: 7 Alignment: HAAAACADAC GDAAACA--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- kkAAGAGCAsy Combined Motif Reverse Complement Reverse Complement GTDTGTTTTC HVTGCTCTTBH GHBTGYTYTTBH Direction: Forward Position #: 2 Overlap #: 9 Alignment: GTDTGTTTTC-- -HVTGCTCTTBH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TAL1TCF3 Reverse Complement Original Motif DBAAKAKCAVHC HVAMCATCTGKT DBAASAKCWGDY Direction: Forward Position #: 1 Overlap #: 12 Alignment: DBAAKAKCAVHC HVAMCATCTGKT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 2 Original Motif Original Motif DBAASAKCWGDY AAAAHAAA DAAABAWMWGDY Direction: Forward Position #: 1 Overlap #: 8 Alignment: DBAASAKCWGDY AAAAHAAA---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 66 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 66 wtATTTTTAww Original Motif Reverse Complement TATAAATR WWTAAAAATAD DTAWAAATRWW Direction: Backward Position #: 2 Overlap #: 8 Alignment: --TATAAATR- WWTAAAAATAD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- waATwAAAATAww Combined Motif Reverse Complement Reverse Complement WWKATTTWTAD DHTATTTTWATHD WDDWWTTTTAATHD Direction: Forward Position #: 2 Overlap #: 10 Alignment: WWKATTTWTAD--- -DHTATTTTWATHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 67 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 67 rgyGCCMyCTksTGGccd Original Motif Original Motif SYGCCCYCTDSTGG RVYGCCCYCTKSTGGCHD CHDSYGCCCYCTDSTGGR Direction: Backward Position #: 4 Overlap #: 14 Alignment: -SYGCCCYCTDSTGG--- RVYGCCCYCTKSTGGCHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Reverse Complement Original Motif MCCASHAGMGGGCKSDDG YDRCCASYAGRKGGCRSYV YDVCCASYAGVGGGCGSHVG Direction: Forward Position #: 3 Overlap #: 17 Alignment: --MCCASHAGMGGGCKSDDG YDRCCASYAGRKGGCRSYV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wgGCCAshAGrGGGCrsy Combined Motif Reverse Complement Original Motif CVHSCGCCCBCTKSTGGBHM HDGCCACHAGRGGGCRBY CVHSHGSCCDCTAGWGGGCABY Direction: Forward Position #: 5 Overlap #: 16 Alignment: CVHSCGCCCBCTKSTGGBHM-- ----HDGCCACHAGRGGGCRBY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif gwGGCCAGmAGAGGGCrby Reverse Complement Reverse Complement KBTGCCCWCTAGDGGSCDSHVG KBKGCCCTCTYCTGGCCHV KBKGCCCTCTHSTGGCCDVHVG Direction: Forward Position #: 1 Overlap #: 19 Alignment: KBTGCCCWCTAGDGGSCDSHVG KBKGCCCTCTYCTGGCCHV--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yvTGCyGCCmCCwGgtG Reverse Complement Original Motif CVHVDGGCCASHAGAGGGCRBY BVTGCTGCCACCWGGDG HVTGCKGCCACYWGRKGGCRBY Direction: Forward Position #: 1 Overlap #: 17 Alignment: CVHVDGGCCASHAGAGGGCRBY BVTGCTGCCACCWGGDG----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 68 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 68 waATwAAAATAww Reverse Complement Reverse Complement TTWWWTWTTTWTTW DHTATTTTWATHD TWTWTTTTTATTWT Direction: Backward Position #: 1 Overlap #: 13 Alignment: TTWWWTWTTTWTTW -DHTATTTTWATHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wtATTTTTAww Combined Motif Reverse Complement Reverse Complement AWAATAAAAAWAWA WWTAAAAATAD AWWATAAAAATAWA Direction: Forward Position #: 3 Overlap #: 11 Alignment: AWAATAAAAAWAWA --WWTAAAAATAD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTwAAAAww Original Motif Original Motif AWWATAAAAATAWA DDTWAAAAHH AWWWWAAAWATAWA Direction: Forward Position #: 1 Overlap #: 10 Alignment: AWWATAAAAATAWA DDTWAAAAHH---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif raCAAAACam Original Motif Original Motif AWWWWAAAWATAWA DACAAAACAH AWYAAAAMAATAWA Direction: Forward Position #: 1 Overlap #: 10 Alignment: AWWWWAAAWATAWA DACAAAACAH---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 52 Original Motif Original Motif AWYAAAAMAATAWA AAATAAAW AAAWAAAAAATAWA Direction: Forward Position #: 1 Overlap #: 8 Alignment: AWYAAAAMAATAWA AAATAAAW------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 69 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 69 rgyGCCMyCTksTGGccd Reverse Complement Reverse Complement ACTCCAGMTCCAGG DDGCCASYAGMGGGCKVM AVKCCAGMWSMRGGCKVM Direction: Forward Position #: 1 Overlap #: 14 Alignment: ACTCCAGMTCCAGG---- DDGCCASYAGMGGGCKVM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asmAGRGGGCrCTGsmkc Reverse Complement Original Motif RVYGCCKRSWRCTGGRVT ASMAGAGGGCRCTGSABH RSCRSMKGGHRCTGGABH Direction: Forward Position #: 1 Overlap #: 18 Alignment: RVYGCCKRSWRCTGGRVT ASMAGAGGGCRCTGSABH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif gwGGCCAGmAGAGGGCrby Original Motif Reverse Complement RSCRSMKGGHRCTGGABH KBKGCCCTCTYCTGGCCHV DBBGCCBKSTDCTGGMBHV Direction: Forward Position #: 1 Overlap #: 18 Alignment: RSCRSMKGGHRCTGGABH- KBKGCCCTCTYCTGGCCHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RXRRAR_DR5 Reverse Complement Original Motif VHBRCCAGHASYBGGCVBH RGKTCABVVRGAGGTCA RGKTCMAGVASHGGKCABH Direction: Forward Position #: 1 Overlap #: 17 Alignment: VHBRCCAGHASYBGGCVBH RGKTCABVVRGAGGTCA-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 67 Original Motif Original Motif RGKTCMAGVASHGGKCABH SYGCCCYCTDSTGG VBGBCMHCTDSHGGKCABH Direction: Forward Position #: 1 Overlap #: 14 Alignment: RGKTCMAGVASHGGKCABH SYGCCCYCTDSTGG----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 70 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar REST Reverse Complement Reverse Complement VRVDGGHACAVDDKGTHCTDWH GGYGCTGTCCATGGTGCTGAA GVHGSTRYMCDDKGTBCTKAHV Direction: Backward Position #: 1 Overlap #: 21 Alignment: VRVDGGHACAVDDKGTHCTDWH -GGYGCTGTCCATGGTGCTGAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PPARG Original Motif Reverse Complement GVHGSTRYMCDDKGTBCTKAHV ABTMGGTCACBGTGACCTAS RVTVGKDCACVDTGWCCTAVHV Direction: Forward Position #: 1 Overlap #: 20 Alignment: GVHGSTRYMCDDKGTBCTKAHV ABTMGGTCACBGTGACCTAS-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Reverse Complement Reverse Complement VHBTAGGWCAHBGTGDYCVAVK MSGKKRCGCWDCABTGBBCD MVGKDGVDCDBBRBKDYBMDVK Direction: Forward Position #: 1 Overlap #: 20 Alignment: VHBTAGGWCAHBGTGDYCVAVK MSGKKRCGCWDCABTGBBCD-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- znf143 Combined Motif Reverse Complement Reverse Complement RVDRBKHRVMBVDGHVCDRCVR GCMWRGCATYRTGGGAMHTB RVDRSDHRGCRHBGTGSKAVVDB Direction: Forward Position #: 4 Overlap #: 19 Alignment: RVDRBKHRVMBVDGHVCDRCVR- ---GCMWRGCATYRTGGGAMHTB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Original Motif Original Motif RVDRSDHRGCRHBGTGSKAVVDB VDBHMAGGTCACCCTGACCY DVBVVDDGKCABBVTGVBMHVDB Direction: Forward Position #: 1 Overlap #: 20 Alignment: RVDRSDHRGCRHBGTGSKAVVDB VDBHMAGGTCACCCTGACCY--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 71 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Arnt Motif 20 Original Motif Reverse Complement CACGTG MACGTG CACGTG Direction: Forward Position #: 1 Overlap #: 6 Alignment: CACGTG MACGTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif MAX Reverse Complement Reverse Complement CACGTG BCACGTGDTD BCACGTGDTD Direction: Forward Position #: 2 Overlap #: 6 Alignment: -CACGTG--- BCACGTGDTD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif USF1 Original Motif Reverse Complement BCACGTGDTD MCACGTG HCACGTGDTD Direction: Forward Position #: 1 Overlap #: 7 Alignment: BCACGTGDTD MCACGTG--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif MYCMAX Reverse Complement Original Motif HAHCACGTGD RASCACGTGGT DAVCACGTGGT Direction: Forward Position #: 1 Overlap #: 10 Alignment: HAHCACGTGD- RASCACGTGGT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Myc Reverse Complement Reverse Complement ACCACGTGVTD DCCACGTGCV DCCACGTGVDD Direction: Forward Position #: 1 Overlap #: 10 Alignment: ACCACGTGVTD DCCACGTGCV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 72 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ArntAhr HIF1AARNT Original Motif Original Motif YGCGTG VBACGTGV VBRCGTGV Direction: Forward Position #: 2 Overlap #: 6 Alignment: -YGCGTG- VBACGTGV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGwGCGss Original Motif Original Motif VBRCGTGV BSCGWGCGBV BSCGCGYGBV Direction: Forward Position #: 2 Overlap #: 8 Alignment: -VBRCGTGV- BSCGWGCGBV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Arnt Original Motif Original Motif BSCGCGYGBV CACGTG CACGTGYGBV Direction: Forward Position #: 1 Overlap #: 6 Alignment: BSCGCGYGBV CACGTG---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 20 Original Motif Reverse Complement CACGTGYGBV MACGTG CACGTGYGBV Direction: Forward Position #: 1 Overlap #: 6 Alignment: CACGTGYGBV MACGTG---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif USF1 Original Motif Original Motif CACGTGYGBV CACGTGR CACGTGBGBV Direction: Forward Position #: 1 Overlap #: 7 Alignment: CACGTGYGBV CACGTGR--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 73 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CREB1 MIZF Original Motif Reverse Complement TGACGTCA GCGGACGTTV KGACGTHAGC Direction: Backward Position #: 1 Overlap #: 8 Alignment: --TGACGTCA GCGGACGTTV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RXRRAR_DR5 Original Motif Reverse Complement KGACGTHAGC TGACCTCKVVBTGAYCK TGACSTHDBCBTGAYCK Direction: Forward Position #: 1 Overlap #: 10 Alignment: KGACGTHAGC------- TGACCTCKVVBTGAYCK ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Reverse Complement Reverse Complement RGKTCABGBDDASGTCA MGGTCAGGGTGACCTRDBHV AGGTCABGBTGACSTSRBHV Direction: Forward Position #: 1 Overlap #: 17 Alignment: RGKTCABGBDDASGTCA--- MGGTCAGGGTGACCTRDBHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR2 Original Motif Reverse Complement AGGTCABGBTGACSTSRBHV BAGGYCABHBTGACCKHV BAGGTCABBBTGACCTHVBHV Direction: Forward Position #: 2 Overlap #: 17 Alignment: -AGGTCABGBTGACSTSRBHV BAGGYCABHBTGACCKHV--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 34 Original Motif Reverse Complement BAGGTCABBBTGACCTHVBHV TGTGGYCA TGWGGYCABBBTGACCTHVBHV Direction: Forward Position #: 2 Overlap #: 7 Alignment: -BAGGTCABBBTGACCTHVBHV TGTGGYCA-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 74 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CTCF Ar Reverse Complement Original Motif BMSMGCCYMCTKSTGGMHM HWDAGHACRHHVTGTHCCHVMV HWDAGMRCMYMCTGBWSSHVMV Direction: Forward Position #: 3 Overlap #: 19 Alignment: --BMSMGCCYMCTKSTGGMHM- HWDAGHACRHHVTGTHCCHVMV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Reverse Complement Original Motif VYVDSSWVCAGRKRGKYCTDWH DGVBCABTGDWGCGKRRCSR VYVDVGHDCASBGRGGYSTDDCSR Direction: Forward Position #: 5 Overlap #: 18 Alignment: VYVDSSWVCAGRKRGKYCTDWH-- ----DGVBCABTGDWGCGKRRCSR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Reverse Complement Original Motif MSGDDASKCCKCVSTGHHCVHVMV VDBHMAGGTCACCCTGACCY VVBBHAGGYCDCVSTGHCCBHVMV Direction: Forward Position #: 1 Overlap #: 20 Alignment: MSGDDASKCCKCVSTGHHCVHVMV VDBHMAGGTCACCCTGACCY---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wgGCCAshAGrGGGCrsy Combined Motif Reverse Complement Original Motif VYVDVGGHCASVGDGMCCTDVBVV HDGCCACHAGRGGGCRBY VYVDHGGCCASHRGRVSGYRVBVV Direction: Forward Position #: 5 Overlap #: 18 Alignment: VYVDVGGHCASVGDGMCCTDVBVV ----HDGCCACHAGRGGGCRBY-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rgyGCCMyCTksTGGccd Combined Motif Reverse Complement Original Motif VVBVKKCSVMCKHSTGGCCHHVMV RVYGCCCYCTKSTGGCHD VVBVKDSCGCCHYCTGSYSGCVHV Direction: Forward Position #: 6 Overlap #: 18 Alignment: VVBVKKCSVMCKHSTGGCCHHVMV -----RVYGCCCYCTKSTGGCHD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 75 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ddit3Cebpa NFYA Reverse Complement Reverse Complement GGRATTGCAKHB BHVCKSATTGGMKBVV VSKVATTGSAKBDBHV Direction: Backward Position #: 2 Overlap #: 12 Alignment: ---GGRATTGCAKHB- BHVCKSATTGGMKBVV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- znf143 Combined Motif Reverse Complement Original Motif VDBHBRTSCAATVYSV BAHYTCCCAKMATGCMWYGC VDBHBDTCCMATMVTBCMWYGC Direction: Forward Position #: 3 Overlap #: 14 Alignment: VDBHBRTSCAATVYSV------ --BAHYTCCCAKMATGCMWYGC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Original Motif Original Motif VDBHBDTCCMATMVTBCMWYGC VDBHMAGGTCACCCTGACCY VDBHHDKSYCABCVTGMCHYGC Direction: Forward Position #: 1 Overlap #: 20 Alignment: VDBHBDTCCMATMVTBCMWYGC VDBHMAGGTCACCCTGACCY-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Ar Reverse Complement Reverse Complement GCMDGRCAVGVTGKSYDDDBHV VRVDGGHACAVDDKGTHCTDWH GVHDGGHACVVTGKGTHCKBHH Direction: Forward Position #: 1 Overlap #: 22 Alignment: GCMDGRCAVGVTGKSYDDDBHV VRVDGGHACAVDDKGTHCTDWH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR2F1 Combined Motif Reverse Complement Original Motif DHVRGHACRCAVBGTDCCHHVC TGAMCTTTGMMCYT CYGAMCTKTGMMCYBDHVRGHA Direction: Backward Position #: 2 Overlap #: 14 Alignment: DHVRGHACRCAVBGTDCCHHVC -------TGAMCTTTGMMCYT- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 76 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- E2F1 Egr1 Original Motif Original Motif TTTSGCGC TTTSGCGC TTTSGCGC Direction: Forward Position #: 1 Overlap #: 8 Alignment: TTTSGCGC TTTSGCGC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AgmAGAGGGCrscAGak Original Motif Reverse Complement TTTSGCGC RTCTGSTGCCCTCTYCT RTYTGSYGCCCTCTYCT Direction: Forward Position #: 2 Overlap #: 8 Alignment: -TTTSGCGC-------- RTCTGSTGCCCTCTYCT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ctCTrsyGCCmCCTast Original Motif Original Motif RTYTGSYGCCCTCTYCT HDCTGSYGCCMCCTAST VTCTGSYGCCCYCTHST Direction: Forward Position #: 1 Overlap #: 17 Alignment: RTYTGSYGCCCTCTYCT HDCTGSYGCCMCCTAST ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rsyAGrkGGCGCCmyCTrsy Reverse Complement Original Motif ASHAGMGGGCMSCAGAB DSYAGRKGGCGCCMYCTRSH ASHAGRKGGCRCCABMTRSH Direction: Forward Position #: 1 Overlap #: 17 Alignment: ASHAGMGGGCMSCAGAB--- DSYAGRKGGCGCCMYCTRSH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif myrGYGCCmCCTast Original Motif Reverse Complement ASHAGRKGGCRCCABMTRSH ASTAGGYGGCGCTBB ASBAGGBGGCGCYVBMTRSH Direction: Forward Position #: 1 Overlap #: 15 Alignment: ASHAGRKGGCRCCABMTRSH ASTAGGYGGCGCTBB----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 77 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- EBF1 PLAG1 Reverse Complement Reverse Complement TCCCTYGGGY CCCCCTTGGGCCCC CCCYCCCTTGGGCC Direction: Backward Position #: 4 Overlap #: 10 Alignment: -TCCCTYGGGY--- CCCCCTTGGGCCCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Zfp423 Original Motif Reverse Complement CCCYCCCTTGGGCC GYRYCCMTKGGYRSC SCMYCCCTKGGBVCC Direction: Forward Position #: 1 Overlap #: 14 Alignment: CCCYCCCTTGGGCC- GYRYCCMTKGGYRSC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CasCAGrGGGCrsy Original Motif Reverse Complement SCMYCCCTKGGBVCC BSKGCCCKCTGGTG BSBGCCCTCKGSBSC Direction: Forward Position #: 1 Overlap #: 14 Alignment: SCMYCCCTKGGBVCC BSKGCCCKCTGGTG- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yrcrGYGCCMyCTGGtG Original Motif Original Motif BSBGCCCTCKGSBSC HVCAGCGCCCYCTGGTG HVCVGYGCCCTCTGGBGC Direction: Forward Position #: 4 Overlap #: 14 Alignment: ---BSBGCCCTCKGSBSC HVCAGCGCCCYCTGGTG- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 67 Combined Motif Reverse Complement Reverse Complement GCVCCAGAGGGCKCBGBD CCASHAGKGGGCKS GCVCCAGMRGGSGSBGBD Direction: Forward Position #: 4 Overlap #: 14 Alignment: GCVCCAGAGGGCKCBGBD ---CCASHAGKGGGCKS- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 78 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Egr1 E2F1 Original Motif Original Motif TTTSGCGC TTTSGCGC TTTSGCGC Direction: Backward Position #: 1 Overlap #: 8 Alignment: TTTSGCGC TTTSGCGC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AgmAGAGGGCrscAGak Original Motif Reverse Complement TTTSGCGC RTCTGSTGCCCTCTYCT RTYTGSYGCCCTCTYCT Direction: Forward Position #: 2 Overlap #: 8 Alignment: -TTTSGCGC-------- RTCTGSTGCCCTCTYCT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ctCTrsyGCCmCCTast Original Motif Original Motif RTYTGSYGCCCTCTYCT HDCTGSYGCCMCCTAST VTCTGSYGCCCYCTHST Direction: Forward Position #: 1 Overlap #: 17 Alignment: RTYTGSYGCCCTCTYCT HDCTGSYGCCMCCTAST ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rsyAGrkGGCGCCmyCTrsy Reverse Complement Original Motif ASHAGMGGGCMSCAGAB DSYAGRKGGCGCCMYCTRSH ASHAGRKGGCRCCABMTRSH Direction: Forward Position #: 1 Overlap #: 17 Alignment: ASHAGMGGGCMSCAGAB--- DSYAGRKGGCGCCMYCTRSH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif myrGYGCCmCCTast Original Motif Reverse Complement ASHAGRKGGCRCCABMTRSH ASTAGGYGGCGCTBB ASBAGGBGGCGCYVBMTRSH Direction: Forward Position #: 1 Overlap #: 15 Alignment: ASHAGRKGGCRCCABMTRSH ASTAGGYGGCGCTBB----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 79 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ELK1 Hand1Tcfe2a Original Motif Reverse Complement VDDCCGGAAR AWRCCAGAMB VDDCCRGAMV Direction: Backward Position #: 1 Overlap #: 10 Alignment: VDDCCGGAAR AWRCCAGAMB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Stat3 Original Motif Original Motif VDDCCRGAMV TTCCAGGAAG TTVCMGGAAR Direction: Forward Position #: 1 Overlap #: 10 Alignment: VDDCCRGAMV TTCCAGGAAG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif agrCCAGmAGrg Original Motif Original Motif TTVCMGGAAR HVGCCAGMAGRG DDVCCRGAAGRG Direction: Forward Position #: 1 Overlap #: 10 Alignment: TTVCMGGAAR-- HVGCCAGMAGRG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rgyGCCMyCTksTGGccd Original Motif Reverse Complement DDVCCRGAAGRG DDGCCASYAGMGGGCKVM DDGCCAGMAGMGGGCKVM Direction: Forward Position #: 1 Overlap #: 12 Alignment: DDVCCRGAAGRG------ DDGCCASYAGMGGGCKVM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Original Motif Original Motif DDGCCAGMAGMGGGCKVM YDRCCASYAGRKGGCRSYV HDGCCASHAGRGGGCGSHV Direction: Forward Position #: 1 Overlap #: 18 Alignment: DDGCCAGMAGMGGGCKVM- YDRCCASYAGRKGGCRSYV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 80 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ELK4 agrCCAGmAGrg Original Motif Original Motif ACCGGAAGT HVGCCAGMAGRG HVRCCRGAAGHG Direction: Forward Position #: 3 Overlap #: 9 Alignment: --ACCGGAAGT- HVGCCAGMAGRG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif dwCAGAAGwh Reverse Complement Reverse Complement CHCTTCKGGKVH HDCTTCTGHD HHCTTCTGGDVH Direction: Forward Position #: 1 Overlap #: 10 Alignment: CHCTTCKGGKVH HDCTTCTGHD-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TAL1TCF3 Reverse Complement Original Motif HVDCCAGAAGHD HVAMCATCTGKT HVAMCAKMWGDD Direction: Forward Position #: 1 Overlap #: 12 Alignment: HVDCCAGAAGHD HVAMCATCTGKT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CasCAGrGGGCrsy Original Motif Reverse Complement HVAMCAKMWGDD BSKGCCCKCTGGTG BVKRCCMKCTGBTG Direction: Forward Position #: 2 Overlap #: 12 Alignment: -HVAMCAKMWGDD- BSKGCCCKCTGGTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rgyGCCMyCTksTGGccd Combined Motif Original Motif Reverse Complement BVKRCCMKCTGBTG DDGCCASYAGMGGGCKVM BDDGCCAGCWGVKGGCKVM Direction: Forward Position #: 2 Overlap #: 13 Alignment: BVKRCCMKCTGBTG----- -DDGCCASYAGMGGGCKVM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 81 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Pax5 Reverse Complement Reverse Complement MGGTCAGGGTGACCTRDBHV MSGKKRCGCWDCABTGBBCD MGGTBAVGCTKVMCTGBBMD Direction: Backward Position #: 1 Overlap #: 20 Alignment: MGGTCAGGGTGACCTRDBHV MSGKKRCGCWDCABTGBBCD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rsyAGrkGGCGCCmyCTrsy Reverse Complement Original Motif HRBBCAGRVYAGCVTBACCY DSYAGRKGGCGCCMYCTRSH DVBHSRKGGCRSCVTCWVSY Direction: Forward Position #: 1 Overlap #: 20 Alignment: HRBBCAGRVYAGCVTBACCY DSYAGRKGGCGCCMYCTRSH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Ar Original Motif Original Motif DVBHSRKGGCRSCVTCWVSY HWDAGHACRHHVTGTHCCHVMV HDHAGADSRYVSYGTHCCVBMV Direction: Forward Position #: 1 Overlap #: 20 Alignment: DVBHSRKGGCRSCVTCWVSY-- HWDAGHACRHHVTGTHCCHVMV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CTCF Combined Motif Original Motif Reverse Complement HDHAGADSRYVSYGTHCCVBMV BMSMGCCYMCTKSTGGMHM HDHAKHVCGCCCCSTBSYGGMVM Direction: Forward Position #: 5 Overlap #: 18 Alignment: HDHAGADSRYVSYGTHCCVBMV- ----BMSMGCCYMCTKSTGGMHM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PPARG Original Motif Reverse Complement HDHAKHVCGCCCCSTBSYGGMVM ABTMGGTCACBGTGACCTAS ADTMGGBCRCVBYSWCCTRBMVM Direction: Forward Position #: 1 Overlap #: 20 Alignment: HDHAKHVCGCCCCSTBSYGGMVM ABTMGGTCACBGTGACCTAS--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 82 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 PPARG Reverse Complement Reverse Complement BAGGYCABHBTGACCKHV ABTMGGTCACBGTGACCTAS YMGGTCACBBTGACCKAVAB Direction: Backward Position #: 1 Overlap #: 18 Alignment: --BAGGYCABHBTGACCKHV ABTMGGTCACBGTGACCTAS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Reverse Complement Original Motif BTVTRGGTCABBGTGACCYM HWDAGHACRHHVTGTHCCHVMV BWDWRGVWCAHBVTGWCCYHVMV Direction: Forward Position #: 2 Overlap #: 19 Alignment: BTVTRGGTCABBGTGACCYM--- -HWDAGHACRHHVTGTHCCHVMV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- znf143 Combined Motif Original Motif Reverse Complement BWDWRGVWCAHBVTGWCCYHVMV GCMWRGCATYRTGGGAMHTB BWVHARRGCABBRTGGBMHHBHV Direction: Forward Position #: 3 Overlap #: 20 Alignment: BWDWRGVWCAHBVTGWCCYHVMV --GCMWRGCATYRTGGGAMHTB- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Original Motif Reverse Complement BWVHARRGCABBRTGGBMHHBHV MSGKKRCGCWDCABTGBBCD MHGBDRVGCABCRBKGBHMDBHV Direction: Forward Position #: 1 Overlap #: 20 Alignment: BWVHARRGCABBRTGGBMHHBHV MSGKKRCGCWDCABTGBBCD--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rsyAGrkGGCGCCmyCTrsy Original Motif Reverse Complement MHGBDRVGCABCRBKGBHMDBHV HSKAGKYGGCGCCRMCTMSD HVGDGKHGSMKCMDVSHMVDBHV Direction: Forward Position #: 1 Overlap #: 20 Alignment: MHGBDRVGCABCRBKGBHMDBHV HSKAGKYGGCGCCRMCTMSD--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 83 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Esrrb NR2F1 Original Motif Reverse Complement VBBYCAAGGTCA AKGYYCAAAGRTCA GBBCMAAGGTCAAK Direction: Backward Position #: 1 Overlap #: 12 Alignment: --VBBYCAAGGTCA AKGYYCAAAGRTCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RXRRAR_DR5 Original Motif Original Motif GBBCMAAGGTCAAK RGKTCABVVRGAGGTCA RGKYCAAGGWCARGTCA Direction: Forward Position #: 1 Overlap #: 14 Alignment: GBBCMAAGGTCAAK--- RGKTCABVVRGAGGTCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif HNF4A Original Motif Original Motif RGKYCAAGGWCARGTCA RGGBCAAAGKYCA RGKYCAARGKBMRGTCA Direction: Forward Position #: 1 Overlap #: 13 Alignment: RGKYCAAGGWCARGTCA RGGBCAAAGKYCA---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Zfx Original Motif Original Motif RGKYCAARGKBMRGTCA BBVGCCBVGGCCTV VGBBCMDRGGCCTGTCA Direction: Forward Position #: 1 Overlap #: 14 Alignment: RGKYCAARGKBMRGTCA BBVGCCBVGGCCTV--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Original Motif Original Motif VGBBCMDRGGCCTGTCA VDBHMAGGTCACCCTGACCY VBBBCAGGKSMCHBTSACCY Direction: Forward Position #: 1 Overlap #: 17 Alignment: VGBBCMDRGGCCTGTCA--- VDBHMAGGTCACCCTGACCY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 84 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- GABPA csCsCCTCCcc Reverse Complement Original Motif VVCACTTCCGG VBCCCCTCCHB VVCMCYTCCGS Direction: Forward Position #: 1 Overlap #: 11 Alignment: VVCACTTCCGG VBCCCCTCCHB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yvTGCyGCCmCCwGgtG Original Motif Original Motif VVCMCYTCCGS BVTGCTGCCACCWGGDG BVYGCYKCCVSCWGGDG Direction: Forward Position #: 1 Overlap #: 11 Alignment: VVCMCYTCCGS------ BVTGCTGCCACCWGGDG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 67 Original Motif Original Motif BVYGCYKCCVSCWGGDG SYGCCCYCTDSTGG VBBCCYBCYVSYKGGDG Direction: Forward Position #: 1 Overlap #: 14 Alignment: BVYGCYKCCVSCWGGDG SYGCCCYCTDSTGG--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CTCF Combined Motif Original Motif Reverse Complement VBBCCYBCYVSYKGGDG BMSMGCCYMCTKSTGGMHM VBBVCMKCCHCCTGGTGGMHM Direction: Forward Position #: 3 Overlap #: 15 Alignment: VBBCCYBCYVSYKGGDG---- --BMSMGCCYMCTKSTGGMHM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rgyGCCMyCTksTGGccd Combined Motif Original Motif Reverse Complement VBBVCMKCCHCCTGGTGGMHM DDGCCASYAGMGGGCKVM VBBVVVGCCASYWGVKGGCBVM Direction: Forward Position #: 5 Overlap #: 17 Alignment: VBBVCMKCCHCCTGGTGGMHM- ----DDGCCASYAGMGGGCKVM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 85 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Hand1Tcfe2a agrCCAGmAGrg Reverse Complement Original Motif AWRCCAGAMB HVGCCAGMAGRG RGHDRCCAGAAG Direction: Backward Position #: 3 Overlap #: 10 Alignment: AWRCCAGAMB-- HVGCCAGMAGRG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif gwGGCCAGmAGAGGGCrby Original Motif Original Motif RGHDRCCAGAAG VHGGCCAGMAGAGGGCRBY VHRGCCASCAGARGGCRBY Direction: Forward Position #: 3 Overlap #: 12 Alignment: --RGHDRCCAGAAG----- VHGGCCAGMAGAGGGCRBY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ELK1 Original Motif Original Motif VHRGCCASCAGARGGCRBY VDDCCGGAAR VHDVCSRMMAGARGGCRBY Direction: Forward Position #: 1 Overlap #: 10 Alignment: VHRGCCASCAGARGGCRBY VDDCCGGAAR--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RUNX1 Reverse Complement Original Motif KBKGCCMTCTYYMSGVHHV BBYTGTGGTTT BBBTGYSGTYTYYMSGVHHV Direction: Forward Position #: 2 Overlap #: 10 Alignment: -KBKGCCMTCTYYMSGVHHV BBYTGTGGTTT--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rgyGCCMyCTksTGGccd Combined Motif Reverse Complement Reverse Complement VHDVCSRMMAKACSKCABVB DDGCCASYAGMGGGCKVM VDDBCCRVHAGASGGCRBVB Direction: Forward Position #: 2 Overlap #: 18 Alignment: VHDVCSRMMAKACSKCABVB -DDGCCASYAGMGGGCKVM- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 86 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- HIF1AARNT MAX Reverse Complement Reverse Complement VCACGTBV BCACGTGDTD TDBCACGTGV Direction: Backward Position #: 3 Overlap #: 8 Alignment: VCACGTBV-- BCACGTGDTD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Mycn Reverse Complement Reverse Complement VCACGTGBHA GCCACGTGSD GCCACGTGBHA Direction: Forward Position #: 2 Overlap #: 9 Alignment: -VCACGTGBHA GCCACGTGSD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Myc Original Motif Reverse Complement GCCACGTGBHA DCCACGTGCV GCCACGTGSVA Direction: Forward Position #: 1 Overlap #: 10 Alignment: GCCACGTGBHA DCCACGTGCV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif MYCMAX Reverse Complement Original Motif TVSCACGTGGC RASCACGTGGT KASCACGTGGY Direction: Forward Position #: 1 Overlap #: 11 Alignment: TVSCACGTGGC RASCACGTGGT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TP53 Original Motif Original Motif KASCACGTGGY MSGGACATGYCCGGGCATGT BVGSACRTGSCCGGGCATGT Direction: Forward Position #: 1 Overlap #: 11 Alignment: KASCACGTGGY--------- MSGGACATGYCCGGGCATGT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 87 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- HNF4A NR2F1 Original Motif Reverse Complement RGGBCAAAGKYCA AKGYYCAAAGRTCA ARGBBCAAAGRTCA Direction: Forward Position #: 2 Overlap #: 13 Alignment: -RGGBCAAAGKYCA AKGYYCAAAGRTCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RXRRAR_DR5 Reverse Complement Reverse Complement TGAMCTTTGVVCMT TGACCTCKVVBTGAYCK TGACCTBTVVVYVDYCK Direction: Forward Position #: 1 Overlap #: 14 Alignment: TGAMCTTTGVVCMT--- TGACCTCKVVBTGAYCK ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Original Motif Reverse Complement TGACCTBTVVVYVDYCK MSGKKRCGCWDCABTGBBCD TGAMCKBTRCVCDDCCKTGBBCD Direction: Forward Position #: 4 Overlap #: 14 Alignment: TGACCTBTVVVYVDYCK------ ---MSGKKRCGCWDCABTGBBCD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR2 Original Motif Original Motif TGAMCKBTRCVCDDCCKTGBBCD VHRGGTCABDBTGMCCTB BDAVSTCWVVDYGHCCTBGBBCD Direction: Forward Position #: 1 Overlap #: 18 Alignment: TGAMCKBTRCVCDDCCKTGBBCD VHRGGTCABDBTGMCCTB----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Ar Reverse Complement Original Motif HGVBCVAGGHCMHVVWGASVTHV HWDAGHACRHHVTGTHCCHVMV HDDDSHASRHHMHGHWSVVVHVV Direction: Forward Position #: 1 Overlap #: 22 Alignment: HGVBCVAGGHCMHVVWGASVTHV HWDAGHACRHHVTGTHCCHVMV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 88 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- INSM1 CTCF Reverse Complement Reverse Complement MGCCCCCTGMCA BMSMGCCYMCTKSTGGMHM GMHMMGCCCCCTGVYRBMS Direction: Backward Position #: 5 Overlap #: 12 Alignment: ---MGCCCCCTGMCA---- BMSMGCCYMCTKSTGGMHM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 67 Original Motif Original Motif GMHMMGCCCCCTGVYRBMS SYGCCCYCTDSTGG GYBCCVCCYVCTGGYRBMS Direction: Forward Position #: 1 Overlap #: 14 Alignment: GMHMMGCCCCCTGVYRBMS SYGCCCYCTDSTGG----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CasCAGrGGGCrsy Original Motif Reverse Complement GYBCCVCCYVCTGGYRBMS BSKGCCCKCTGGTG BGBGCCCYCTGSTGGYRBMS Direction: Forward Position #: 2 Overlap #: 13 Alignment: -GYBCCVCCYVCTGGYRBMS BSKGCCCKCTGGTG------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yrcrGYGCCMyCTGGtG Original Motif Original Motif BGBGCCCYCTGSTGGYRBMS HVCAGCGCCCYCTGGTG BVBRSCGCCYBCTGGYGBMS Direction: Forward Position #: 1 Overlap #: 17 Alignment: BGBGCCCYCTGSTGGYRBMS HVCAGCGCCCYCTGGTG--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rgyGCCMyCTksTGGccd Combined Motif Original Motif Reverse Complement BVBRSCGCCYBCTGGYGBMS DDGCCASYAGMGGGCKVM BVBRVBGCCMSCWGVBGGCGVM Direction: Forward Position #: 5 Overlap #: 16 Alignment: BVBRSCGCCYBCTGGYGBMS-- ----DDGCCASYAGMGGGCKVM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 89 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Klf4 csCSCCdCCCcs Original Motif Reverse Complement DGGGYGKGGC VDGGGDGGGGBV VDGGGHGGGGCV Direction: Forward Position #: 2 Overlap #: 10 Alignment: -DGGGYGKGGC- VDGGGDGGGGBV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif csCsCCTCCcc Reverse Complement Original Motif VGCCCCHCCCHV VBCCCCTCCHB VBCCCCWCCCHV Direction: Forward Position #: 1 Overlap #: 11 Alignment: VGCCCCHCCCHV VBCCCCTCCHB- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asmAGRGGGCrCTGsmkc Reverse Complement Original Motif VDGGGWGGGGBV ASMAGAGGGCRCTGSABH VBVRGAGGGSVSTGSABH Direction: Forward Position #: 1 Overlap #: 12 Alignment: VDGGGWGGGGBV------ ASMAGAGGGCRCTGSABH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif myrGYGCCmCCTast Original Motif Reverse Complement VBVRGAGGGSVSTGSABH ASTAGGYGGCGCTBB VSDAGRKGGCGCTGBABH Direction: Forward Position #: 1 Overlap #: 15 Alignment: VBVRGAGGGSVSTGSABH ASTAGGYGGCGCTBB--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yvTGCyGCCmCCwGgtG Reverse Complement Original Motif DBTBCAGCGCCYMCTDSB BVTGCTGCCACCWGGDG BBTGCWGCSMCCHSKDGB Direction: Forward Position #: 1 Overlap #: 17 Alignment: DBTBCAGCGCCYMCTDSB BVTGCTGCCACCWGGDG- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 90 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mafb asmAGRGGGCrCTGsmkc Original Motif Original Motif GCTGACDB ASMAGAGGGCRCTGSABH GCTGMMBBASMAGAGGGC Direction: Backward Position #: 1 Overlap #: 8 Alignment: ----------GCTGACDB ASMAGAGGGCRCTGSABH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PPARG Original Motif Original Motif GCTGMMBBASMAGAGGGC STAGGTCACBGTGACCYABT STAGGTCACGSTGACCHAVHAGAGGGC Direction: Forward Position #: 10 Overlap #: 11 Alignment: ---------GCTGMMBBASMAGAGGGC STAGGTCACBGTGACCYABT------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR2 Original Motif Original Motif STAGGTCACGSTGACCHAVHAGAGGGC VHRGGTCABDBTGMCCTB VTRGGTCABGBTGACCYVVHAGAGGGC Direction: Forward Position #: 1 Overlap #: 18 Alignment: STAGGTCACGSTGACCHAVHAGAGGGC VHRGGTCABDBTGMCCTB--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yvTGCyGCCmCCwGgtG Reverse Complement Original Motif GCCCTCTHVBMGGTCABCBTGACCKAV BVTGCTGCCACCWGGDG BVKSCYKCYMCYWGGBSABCBTGACCKAV Direction: Forward Position #: 3 Overlap #: 15 Alignment: --GCCCTCTHVBMGGTCABCBTGACCKAV BVTGCTGCCACCWGGDG------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RXRRAR_DR5 Reverse Complement Reverse Complement VTRGGTCABGBTSVCCWKGYKGYKGSYVV TGACCTCKVVBTGAYCK TDASSTCWVVBTGACCKKGYKGYKGSYVV Direction: Forward Position #: 1 Overlap #: 17 Alignment: VTRGGTCABGBTSVCCWKGYKGYKGSYVV TGACCTCKVVBTGAYCK------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 91 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- MAX MYCMAX Original Motif Original Motif DAHCACGTGD RASCACGTGGT DAVCACGTGGT Direction: Forward Position #: 1 Overlap #: 10 Alignment: DAHCACGTGD- RASCACGTGGT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TAL1TCF3 Reverse Complement Reverse Complement ACCACGTGVTH ARCAGATGRTVD AVCASRTGRTHD Direction: Forward Position #: 1 Overlap #: 11 Alignment: ACCACGTGVTH- ARCAGATGRTVD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif grCCACwAGrk Original Motif Reverse Complement AVCASRTGRTHD YMCTWGTGGHH HVCWHGTGGBHD Direction: Forward Position #: 1 Overlap #: 11 Alignment: AVCASRTGRTHD YMCTWGTGGHH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif grCCACyAGAkG Original Motif Reverse Complement HVCWHGTGGBHD CYTCTMGTGGHH CHTCTHGTGGHHD Direction: Forward Position #: 2 Overlap #: 11 Alignment: -HVCWHGTGGBHD CYTCTMGTGGHH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NHLH1 Original Motif Reverse Complement CHTCTHGTGGHHD VCGCAGCTGCGV CYBCWGSTGSDVD Direction: Forward Position #: 1 Overlap #: 12 Alignment: CHTCTHGTGGHHD VCGCAGCTGCGV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 92 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- MIZF GABPA Original Motif Reverse Complement BAACGTCCGC VVCACTTCCGG GBHMMSTYCSS Direction: Backward Position #: 2 Overlap #: 10 Alignment: BAACGTCCGC- VVCACTTCCGG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- yrcrGYGCCMyCTGGtG Combined Motif Original Motif Original Motif GBHMMSTYCSS HVCAGCGCCCYCTGGTG GBVMMGYKCCCYCTGGTG Direction: Forward Position #: 2 Overlap #: 10 Alignment: GBHMMSTYCSS------- -HVCAGCGCCCYCTGGTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asmAGRGGGCrCTGsmkc Original Motif Reverse Complement GBVMMGYKCCCYCTGGTG DBTSCAGMGCCCTCTRST DSBVCAGYGCCCTCTGSTG Direction: Forward Position #: 2 Overlap #: 17 Alignment: -GBVMMGYKCCCYCTGGTG DBTSCAGMGCCCTCTRST- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif MYCMAX Reverse Complement Original Motif CASCAGAGGGCKCTGVVSH RASCACGTGGT VASCASRKGGYKCTGVVSH Direction: Forward Position #: 1 Overlap #: 11 Alignment: CASCAGAGGGCKCTGVVSH RASCACGTGGT-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR2 Reverse Complement Reverse Complement DSBVCAGYKCCRMSTGSTV BAGGYCABHBTGACCKHV BVGBBCASHBYSACCTDVTV Direction: Forward Position #: 2 Overlap #: 17 Alignment: -DSBVCAGYKCCRMSTGSTV BAGGYCABHBTGACCKHV-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 93 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Myb Myf Reverse Complement Original Motif CAACVGMC MRGCARCWGSWG MRGCAACDGCHG Direction: Forward Position #: 4 Overlap #: 8 Alignment: ---CAACVGMC- MRGCARCWGSWG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif HNF4A Reverse Complement Reverse Complement CHGCDGTTGCKR TGMYCTTTGBCCK TGMYCTTTSHVCDGTTGCKR Direction: Forward Position #: 9 Overlap #: 5 Alignment: --------CHGCDGTTGCKR TGMYCTTTGBCCK------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TAL1TCF3 Reverse Complement Original Motif MRGCAACDGVDSAAAGKYCA HVAMCATCTGKT HVAVCADCTGBTSAAAGKYCA Direction: Forward Position #: 2 Overlap #: 11 Alignment: -MRGCAACDGVDSAAAGKYCA HVAMCATCTGKT--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RUNX1 Original Motif Reverse Complement HVAVCADCTGBTSAAAGKYCA AAACCACAKVB HMACCAHMKGBTSAAAGKYCA Direction: Forward Position #: 1 Overlap #: 11 Alignment: HVAVCADCTGBTSAAAGKYCA AAACCACAKVB---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NFYA Original Motif Original Motif HMACCAHMKGBTSAAAGKYCA VBBRRCCAATSRGVDB VHVAVCMAATSVBVAAAGKYCA Direction: Forward Position #: 2 Overlap #: 15 Alignment: -HMACCAHMKGBTSAAAGKYCA VBBRRCCAATSRGVDB------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 94 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Myc Mycn Original Motif Original Motif VGCACGTGGH HSCACGTGGC VSCACGTGGC Direction: Backward Position #: 1 Overlap #: 10 Alignment: VGCACGTGGH HSCACGTGGC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif MYCMAX Reverse Complement Reverse Complement GCCACGTGSV ACCACGTGSTM DCCACGTGSDM Direction: Forward Position #: 1 Overlap #: 10 Alignment: GCCACGTGSV- ACCACGTGSTM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yvTGCyGCCmCCwGgtG Reverse Complement Reverse Complement RDSCACGTGGD CDCCWGGTGGCAGCAVV VDSCASGTGGCAGCAVV Direction: Forward Position #: 1 Overlap #: 11 Alignment: RDSCACGTGGD------ CDCCWGGTGGCAGCAVV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asCAGrkGGCrsy Reverse Complement Reverse Complement BVTGCTGCCACSTGSDV BSKGCCCMCTGST BVTGCYBCCWSSTGSDV Direction: Forward Position #: 1 Overlap #: 13 Alignment: BVTGCTGCCACSTGSDV BSKGCCCMCTGST---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif grCCACwAGrk Reverse Complement Original Motif VDSCASSWGGBKGCAVV DDCCACWAGRK VDCCACHAGRBKGCAVV Direction: Forward Position #: 1 Overlap #: 11 Alignment: VDSCASSWGGBKGCAVV DDCCACWAGRK------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 95 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- MYCMAX TAL1TCF3 Original Motif Original Motif RASCACGTGGT HVAMCATCTGKT DAMCAYSTGGTH Direction: Backward Position #: 1 Overlap #: 11 Alignment: -RASCACGTGGT HVAMCATCTGKT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif grCCACwAGrk Reverse Complement Original Motif DACCASKTGRTH DDCCACWAGRK DVCCACDWGRTH Direction: Forward Position #: 1 Overlap #: 11 Alignment: DACCASKTGRTH DDCCACWAGRK- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yvTGCyGCCmCCwGgtG Reverse Complement Reverse Complement DAMCWDGTGGBH CDCCWGGTGGCAGCAVV VAMCWDGTGGCMGCAVV Direction: Forward Position #: 1 Overlap #: 12 Alignment: DAMCWDGTGGBH----- CDCCWGGTGGCAGCAVV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Myf Original Motif Reverse Complement VAMCWDGTGGCMGCAVV CWSCWGMTGCKR CASCWGSTGSBRGCAVV Direction: Forward Position #: 1 Overlap #: 12 Alignment: VAMCWDGTGGCMGCAVV CWSCWGMTGCKR----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CTCF Combined Motif Reverse Complement Reverse Complement BVTGCKVSCASCWGSTG BMSMGCCYMCTKSTGGMHM BVTVCHGCCMMCTGSTGGMHM Direction: Forward Position #: 3 Overlap #: 15 Alignment: BVTGCKVSCASCWGSTG---- --BMSMGCCYMCTKSTGGMHM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 96 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mycn Myc Reverse Complement Reverse Complement GCCACGTGSD DCCACGTGCV GCCACGTGSV Direction: Forward Position #: 1 Overlap #: 10 Alignment: GCCACGTGSD DCCACGTGCV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif MYCMAX Original Motif Reverse Complement GCCACGTGSV ACCACGTGSTM DCCACGTGSDM Direction: Forward Position #: 1 Overlap #: 10 Alignment: GCCACGTGSV- ACCACGTGSTM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yvTGCyGCCmCCwGgtG Reverse Complement Reverse Complement RDSCACGTGGD CDCCWGGTGGCAGCAVV VDSCASGTGGCAGCAVV Direction: Forward Position #: 1 Overlap #: 11 Alignment: RDSCACGTGGD------ CDCCWGGTGGCAGCAVV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asCAGrkGGCrsy Reverse Complement Reverse Complement BVTGCTGCCACSTGSDV BSKGCCCMCTGST BVTGCYBCCWSSTGSDV Direction: Forward Position #: 1 Overlap #: 13 Alignment: BVTGCTGCCACSTGSDV BSKGCCCMCTGST---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CTCF Combined Motif Original Motif Reverse Complement BVTGCYBCCWSSTGSDV BMSMGCCYMCTKSTGGMHM BVKGCCGCCYSCTGSTGGMHM Direction: Forward Position #: 3 Overlap #: 15 Alignment: BVTGCYBCCWSSTGSDV---- --BMSMGCCYMCTKSTGGMHM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 97 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Myf NHLH1 Reverse Complement Reverse Complement CWSCWGMTGCKR VCGCAGCTGCGV CHGCAGCTGCGV Direction: Forward Position #: 1 Overlap #: 12 Alignment: CWSCWGMTGCKR VCGCAGCTGCGV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Reverse Complement Original Motif VCGCAGCTGCDG YDRCCASYAGRKGGCRSYV YVVSCASCWGSKGGCRSYV Direction: Forward Position #: 2 Overlap #: 12 Alignment: -VCGCAGCTGCDG------ YDRCCASYAGRKGGCRSYV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CasCAGrGGGCrsy Original Motif Reverse Complement YVVSCASCWGSKGGCRSYV BSKGCCCKCTGGTG BBBGCCMKCTGSKGGCRSYV Direction: Forward Position #: 2 Overlap #: 13 Alignment: -YVVSCASCWGSKGGCRSYV BSKGCCCKCTGGTG------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rgyGCCMyCTksTGGccd Combined Motif Reverse Complement Reverse Complement BMSMGCCRSCAGYYGGCBBB DDGCCASYAGMGGGCKVM BMVVGCCASCAGMBGGCBBH Direction: Forward Position #: 3 Overlap #: 18 Alignment: BMSMGCCRSCAGYYGGCBBB --DDGCCASYAGMGGGCKVM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 69 Combined Motif Reverse Complement Reverse Complement DBBGCCBRCTGSTGGCVVYV ACTCCAGMTCCAGG DVCKCCAGCTBCWGGCVVYV Direction: Forward Position #: 2 Overlap #: 14 Alignment: DBBGCCBRCTGSTGGCVVYV -ACTCCAGMTCCAGG----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 98 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- MZF1_1-4 INSM1 Reverse Complement Reverse Complement TCCCCV MGCCCCCTGMCA MGYCCCCWGMCA Direction: Forward Position #: 3 Overlap #: 6 Alignment: --TCCCCV---- MGCCCCCTGMCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif EBF1 Reverse Complement Original Motif TGYCWGGGGMCR MCCCMAGGGA HSYCHRGGGACR Direction: Forward Position #: 1 Overlap #: 10 Alignment: TGYCWGGGGMCR MCCCMAGGGA-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif csCSCCdCCCcs Original Motif Reverse Complement HSYCHRGGGACR VDGGGDGGGGBV BSGSGRGGGRCR Direction: Forward Position #: 1 Overlap #: 12 Alignment: HSYCHRGGGACR VDGGGDGGGGBV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif MZF1_5-13 Reverse Complement Reverse Complement MGMCCCMCSCSV BTHCCCCTYB HKMCCCCYBBSV Direction: Forward Position #: 1 Overlap #: 10 Alignment: MGMCCCMCSCSV BTHCCCCTYB-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccAsCCCCAcc Original Motif Original Motif HKMCCCCYBBSV HVASCCCCABH HBACCCCCABBV Direction: Forward Position #: 1 Overlap #: 11 Alignment: HKMCCCCYBBSV HVASCCCCABH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 99 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- MZF1_5-13 INSM1 Original Motif Original Motif BKAGGGGDAD TGYCAGGGGGCR BBAGGGGGHRTG Direction: Backward Position #: 1 Overlap #: 10 Alignment: --BKAGGGGDAD TGYCAGGGGGCR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AgmAGAGGGCrscAGak Original Motif Original Motif BBAGGGGGHRTG AGMAGAGGGCASCAGAK ABHAGRGGGCRKBAGAK Direction: Forward Position #: 2 Overlap #: 12 Alignment: -BBAGGGGGHRTG---- AGMAGAGGGCASCAGAK ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif znf143 Original Motif Reverse Complement ABHAGRGGGCRKBAGAK GCMWRGCATYRTGGGAMHTB RSMAGGSRKCRTGRGADHTB Direction: Forward Position #: 1 Overlap #: 17 Alignment: ABHAGRGGGCRKBAGAK--- GCMWRGCATYRTGGGAMHTB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 67 Original Motif Reverse Complement RSMAGGSRKCRTGRGADHTB CCASHAGKGGGCKS CCASHAGGGGGCDBGRGADHTB Direction: Forward Position #: 3 Overlap #: 12 Alignment: --RSMAGGSRKCRTGRGADHTB CCASHAGKGGGCKS-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- gwGGCCAGmAGAGGGCrby Combined Motif Original Motif Reverse Complement CCASHAGGGGGCDBGRGADHTB KBKGCCCTCTYCTGGCCHV CCASHAGGGGGCDBGKGMCCTCTYCTGGCCHV Direction: Forward Position #: 14 Overlap #: 9 Alignment: CCASHAGGGGGCDBGRGADHTB---------- -------------KBKGCCCTCTYCTGGCCHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 100 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NFE2L2 TP53 Reverse Complement Reverse Complement TGCTDWGTCAK ACATGCCCGGKCATGTCCSR ACATGCYVRGTCATGTCCSR Direction: Forward Position #: 4 Overlap #: 11 Alignment: ---TGCTDWGTCAK------ ACATGCCCGGKCATGTCCSR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Reverse Complement Reverse Complement MSGGACATGACMVMGCATGT MGGTCAGGGTGACCTRDBHV MGGTCAGGGTGACCBGGRCATGACMVMGCATGT Direction: Forward Position #: 14 Overlap #: 7 Alignment: -------------MSGGACATGACMVMGCATGT MGGTCAGGGTGACCTRDBHV------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGGCrsTGCrs Original Motif Original Motif MGGTCAGGGTGACCBGGRCATGACMVMGCATGT VVGGCRSTGCVB VGGKCRSKGYGVCCBGGRCATGACMVMGCATGT Direction: Forward Position #: 1 Overlap #: 12 Alignment: MGGTCAGGGTGACCBGGRCATGACMVMGCATGT VVGGCRSTGCVB--------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asmAGRGGGCrCTGsmkc Original Motif Reverse Complement VGGKCRSKGYGVCCBGGRCATGACMVMGCATGT DBTSCAGMGCCCTCTRST VBKGCAGHGCSCYCTRVDCATGACMVMGCATGT Direction: Forward Position #: 1 Overlap #: 18 Alignment: VGGKCRSKGYGVCCBGGRCATGACMVMGCATGT DBTSCAGMGCCCTCTRST--------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Original Motif Original Motif VBKGCAGHGCSCYCTRVDCATGACMVMGCATGT DGVBCABTGDWGCGKRRCSR VBKGCAGDGHBCHCTGVDSMKGRVCSVGCATGT Direction: Forward Position #: 8 Overlap #: 20 Alignment: VBKGCAGHGCSCYCTRVDCATGACMVMGCATGT -------DGVBCABTGDWGCGKRRCSR------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 101 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NFIC TLX1NFIC Original Motif Reverse Complement TTGGCD TTGGCHDBSTGCCA TTGGCHDBSTGCCA Direction: Forward Position #: 1 Overlap #: 6 Alignment: TTGGCD-------- TTGGCHDBSTGCCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NFYA Original Motif Reverse Complement TTGGCHDBSTGCCA BHVCKSATTGGMKBVV BHVCKSATTGGCDBVVTGCCA Direction: Forward Position #: 8 Overlap #: 9 Alignment: -------TTGGCHDBSTGCCA BHVCKSATTGGMKBVV----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wgGCCAshAGrGGGCrsy Combined Motif Original Motif Original Motif BHVCKSATTGGCDBVVTGCCA HDGCCACHAGRGGGCRBY BHVCKSATTGGCHDGCYRCCAGRGGGCRBY Direction: Forward Position #: 13 Overlap #: 9 Alignment: BHVCKSATTGGCDBVVTGCCA--------- ------------HDGCCACHAGRGGGCRBY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rgyGCCMyCTksTGGccd Reverse Complement Original Motif KBKGCCCKCTGGMKGCHHGCCAATSRGVDB RVYGCCCYCTKSTGGCHD DVYGCCCTCTKSYGGCHDGCCAATSRGVDB Direction: Forward Position #: 1 Overlap #: 18 Alignment: KBKGCCCKCTGGMKGCHHGCCAATSRGVDB RVYGCCCYCTKSTGGCHD------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- agrCCAGmAGrg Combined Motif Reverse Complement Reverse Complement BHVCKSATTGGCDDGCCMSYAGAGGGCMVH CKCTRCTGGCVH BHDCTRMTKGSCDDGCCMSYAGAGGGCMVH Direction: Forward Position #: 2 Overlap #: 12 Alignment: BHVCKSATTGGCDDGCCMSYAGAGGGCMVH -CKCTRCTGGCVH----------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 102 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NF-kappaB RELA Original Motif Original Motif GGGRMTTYCC GGGRATTTCC GGGRATTTCC Direction: Backward Position #: 1 Overlap #: 10 Alignment: GGGRMTTYCC GGGRATTTCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NFKB1 Original Motif Original Motif GGGRATTTCC GGGGRTTCCCC GGGRATTYCCC Direction: Forward Position #: 1 Overlap #: 10 Alignment: GGGRATTTCC- GGGGRTTCCCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TP53 Reverse Complement Original Motif GGGKAATMCCC MSGGACATGYCCGGGCATGT MGGGRMATSCCCGGGCATGT Direction: Forward Position #: 2 Overlap #: 11 Alignment: -GGGKAATMCCC-------- MSGGACATGYCCGGGCATGT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- asmAGRGGGCrCTGsmkc Combined Motif Original Motif Original Motif MGGGRMATSCCCGGGCATGT ASMAGAGGGCRCTGSABH CCCGGGCATGTCGSKGCATVMGGGRMATSCC Direction: Backward Position #: 12 Overlap #: 9 Alignment: ---------MGGGRMATSCCCGGGCATGT -----------ASMAGAGGGCRCTGSABH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TLX1NFIC Combined Motif Reverse Complement Original Motif GGSATRKCCCRVATGCRSCGACATGCCCGGG TGGCASBDHGCCAA GGSATGGCMCVVDKCCAVCGACATGCCCGGG Direction: Forward Position #: 5 Overlap #: 14 Alignment: GGSATRKCCCRVATGCRSCGACATGCCCGGG ----TGGCASBDHGCCAA------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 103 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NFKB1 TP53 Reverse Complement Original Motif GGGGAAKCCCC MSGGACATGYCCGGGCATGT MGGGRCATSCCCGGGCATGT Direction: Forward Position #: 2 Overlap #: 11 Alignment: -GGGGAAKCCCC-------- MSGGACATGYCCGGGCATGT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Tcfcp2l1 Original Motif Reverse Complement MGGGRCATSCCCGGGCATGT CKGGDTBDMMCTGG CDGGDHDKVCCYGGGCATGT Direction: Forward Position #: 1 Overlap #: 14 Alignment: MGGGRCATSCCCGGGCATGT CKGGDTBDMMCTGG------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rsyAGrkGGCGCCmyCTrsy Reverse Complement Original Motif ACATGCCCKGGVRDDHCCHG DSYAGRKGGCGCCMYCTRSH DSYAGRKGGCGCCACMTGCCCKGGVRDDHCCHG Direction: Forward Position #: 14 Overlap #: 7 Alignment: -------------ACATGCCCKGGVRDDHCCHG DSYAGRKGGCGCCMYCTRSH------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- asmAGRGGGCrCTGsmkc Combined Motif Original Motif Reverse Complement DSYAGRKGGCGCCACMTGCCCKGGVRDDHCCHG DBTSCAGMGCCCTCTRST DSBHKGBRGCGCCMYCTRCYCKGGVRDDHCCHG Direction: Forward Position #: 3 Overlap #: 18 Alignment: DSYAGRKGGCGCCACMTGCCCKGGVRDDHCCHG --DBTSCAGMGCCCTCTRST------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Spz1 Reverse Complement Original Motif CDGGDHDKVCCYGMGMAGMRGGCGCKBCYHVSD AGGGTAWCAGC MGGGTWWBABCYGMGMAGMRGGCGCKBCYHVSD Direction: Forward Position #: 1 Overlap #: 11 Alignment: CDGGDHDKVCCYGMGMAGMRGGCGCKBCYHVSD AGGGTAWCAGC---------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 104 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NFYA Pax5 Original Motif Reverse Complement VBBRRCCAATSRGVDB MSGKKRCGCWDCABTGBBCD BCDVGBDRCSMATCAGHDBM Direction: Backward Position #: 4 Overlap #: 16 Alignment: -VBBRRCCAATSRGVDB--- MSGKKRCGCWDCABTGBBCD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif znf143 Original Motif Original Motif BCDVGBDRCSMATCAGHDBM BAHYTCCCAKMATGCMWYGC BMDBDYCMMBMATSMVHDBM Direction: Forward Position #: 1 Overlap #: 20 Alignment: BCDVGBDRCSMATCAGHDBM BAHYTCCCAKMATGCMWYGC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Original Motif Original Motif BMDBDYCMMBMATSMVHDBM VHRGGTCABDBTGMCCTB BMHVKSYCABVDTGMCHTBM Direction: Forward Position #: 2 Overlap #: 18 Alignment: BMDBDYCMMBMATSMVHDBM -VHRGGTCABDBTGMCCTB- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CTCF Combined Motif Original Motif Original Motif BMHVKSYCABVDTGMCHTBM YDRCCASYAGRKGGCRSYV BMHBDGCCASHAKGDGBYRCYV Direction: Forward Position #: 4 Overlap #: 17 Alignment: BMHVKSYCABVDTGMCHTBM-- ---YDRCCASYAGRKGGCRSYV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Ar Reverse Complement Reverse Complement BMGMKBCHCYTDSTGGCHVHRB VRVDGGHACAVDDKGTHCTDWH BVVVGGHACHBDBTGKHCDHDB Direction: Forward Position #: 1 Overlap #: 22 Alignment: BMGMKBCHCYTDSTGGCHVHRB VRVDGGHACAVDDKGTHCTDWH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 105 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NHLH1 Myf Reverse Complement Reverse Complement VCGCAGCTGCGV CWSCWGMTGCKR CHGCAGCTGCGV Direction: Forward Position #: 1 Overlap #: 12 Alignment: VCGCAGCTGCGV CWSCWGMTGCKR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Pax5 Reverse Complement Reverse Complement VCGCAGCTGCDG MSGKKRCGCWDCABTGBBCD MSGBKMMGCTGCDGTGBBCD Direction: Forward Position #: 3 Overlap #: 12 Alignment: --VCGCAGCTGCDG------ MSGKKRCGCWDCABTGBBCD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssGGCrsTGCrs Combined Motif Reverse Complement Reverse Complement HGVBCACDGCAGCYRYVCSR BVGCASMGCCVV HGVBBHGCRSMGCCVBVCSR Direction: Forward Position #: 5 Overlap #: 12 Alignment: HGVBCACDGCAGCYRYVCSR ----BVGCASMGCCVV---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rgyGCCMyCTksTGGccd Combined Motif Reverse Complement Reverse Complement MSGBBVGGCYSKGCHBBBCD DDGCCASYAGMGGGCKVM MSGBDVGSCWSBRGHGGGCKVM Direction: Forward Position #: 5 Overlap #: 16 Alignment: MSGBBVGGCYSKGCHBBBCD-- ----DDGCCASYAGMGGGCKVM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- yvTGCyGCCmCCwGgtG Combined Motif Reverse Complement Reverse Complement RVYGCCCHCKVSWGSCVHVCSR CDCCWGGTGGCAGCAVV RVYGCVCCHKVYKGCMGCAVVR Direction: Forward Position #: 5 Overlap #: 17 Alignment: RVYGCCCHCKVSWGSCVHVCSR ----CDCCWGGTGGCAGCAVV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 106 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Nkx3-2 Pax5 Reverse Complement Reverse Complement BVCACTKAH MSGKKRCGCWDCABTGBBCD BTGBBCDBVCRCTKVVMSGK Direction: Backward Position #: 8 Overlap #: 9 Alignment: ----BVCACTKAH------- MSGKKRCGCWDCABTGBBCD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NFYA Reverse Complement Reverse Complement YCSRBVRAGKGBVHGVBCAB BHVCKSATTGGMKBVV BCVVKVAWKGGHDBRVBCAB Direction: Forward Position #: 1 Overlap #: 16 Alignment: YCSRBVRAGKGBVHGVBCAB BHVCKSATTGGMKBVV---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- GABPA Combined Motif Original Motif Original Motif BCVVKVAWKGGHDBRVBCAB CCGGAAGTGVV BCCGGAADTGGVDBRVBCAB Direction: Forward Position #: 2 Overlap #: 11 Alignment: BCVVKVAWKGGHDBRVBCAB -CCGGAAGTGVV-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RUNX1 Combined Motif Original Motif Original Motif BCCGGAADTGGVDBRVBCAB BBYTGTGGTTT BCCGKHWGTGGBBDRVBCAB Direction: Forward Position #: 4 Overlap #: 11 Alignment: BCCGGAADTGGVDBRVBCAB ---BBYTGTGGTTT------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Mycn Original Motif Reverse Complement BCCGKHWGTGGBBDRVBCAB GCCACGTGSD BCCVCGTGBGGBBDRVBCAB Direction: Forward Position #: 1 Overlap #: 10 Alignment: BCCGKHWGTGGBBDRVBCAB GCCACGTGSD---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 107 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR2F1 RXRRAR_DR5 Reverse Complement Original Motif AKGYYCAAAGRTCA RGKTCABVVRGAGGTCA DBRBBCAAAGGTCARGK Direction: Backward Position #: 1 Overlap #: 14 Alignment: ---AKGYYCAAAGRTCA RGKTCABVVRGAGGTCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR2 Reverse Complement Reverse Complement YCKTGACCTTTGBVKBD BAGGYCABHBTGACCKHV BMSKTSACCBTKRCCKBD Direction: Forward Position #: 2 Overlap #: 17 Alignment: -YCKTGACCTTTGBVKBD BAGGYCABHBTGACCKHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Reverse Complement Reverse Complement DVRGGKYAVGGTSAYSRB GGYGCTGTCCATGGTGCTGAA GGYDCWGKCCAHGGTSMYGAV Direction: Forward Position #: 4 Overlap #: 18 Alignment: ---DVRGGKYAVGGTSAYSRB GGYGCTGTCCATGGTGCTGAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NFYA Reverse Complement Original Motif BTCMRSACCHTGGRCWGHKCC VBBRRCCAATSRGVDB BBCARCMMMTBRGVVDGHKCC Direction: Forward Position #: 1 Overlap #: 16 Alignment: BTCMRSACCHTGGRCWGHKCC VBBRRCCAATSRGVDB----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Pax5 Original Motif Reverse Complement BBCARCMMMTBRGVVDGHKCC MSGKKRCGCWDCABTGBBCD MSGBKVMGCHHMHBDGVBMDHKCC Direction: Forward Position #: 4 Overlap #: 17 Alignment: ---BBCARCMMMTBRGVVDGHKCC MSGKKRCGCWDCABTGBBCD---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 108 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR4A2 ESR1 Original Motif Original Motif AAGGTCAC VDBHMAGGTCACCCTGACCY VDBHVAGGTCACCCTGACCY Direction: Forward Position #: 5 Overlap #: 8 Alignment: ----AAGGTCAC-------- VDBHMAGGTCACCCTGACCY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR2 Reverse Complement Reverse Complement MGGTCAGGGTGACCTBDBHV BAGGYCABHBTGACCKHV BAGGTCABBVTGACCTHDBHV Direction: Forward Position #: 2 Overlap #: 17 Alignment: -MGGTCAGGGTGACCTBDBHV BAGGYCABHBTGACCKHV--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARG Combined Motif Reverse Complement Original Motif VDBHHAGGTCAVBBTGACCTB STAGGTCACBGTGACCYABT VDBVWAGGTCAVBBTGACCYVBT Direction: Forward Position #: 4 Overlap #: 18 Alignment: VDBHHAGGTCAVBBTGACCTB-- ---STAGGTCACBGTGACCYABT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Original Motif Original Motif VDBVWAGGTCAVBBTGACCYVBT HWDAGHACRHHVTGTHCCHVMV VDHHWAGRWCAHBVTGWCCYVVWV Direction: Forward Position #: 3 Overlap #: 21 Alignment: VDBVWAGGTCAVBBTGACCYVBT- --HWDAGHACRHHVTGTHCCHVMV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 10 Combined Motif Reverse Complement Reverse Complement VWVBKGGWCAVBDTGWMCTWHDHV GAGGCCAG VWVGAGGMCAGBDTGWMCTWHDHV Direction: Forward Position #: 4 Overlap #: 8 Alignment: VWVBKGGWCAVBDTGWMCTWHDHV ---GAGGCCAG------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 109 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 ESR1 Reverse Complement Reverse Complement MSGKKRCGCWDCABTGBBCD MGGTCAGGGTGACCTRDBHV MGGTBAVGCTKVMCTGBBMD Direction: Backward Position #: 1 Overlap #: 20 Alignment: MSGKKRCGCWDCABTGBBCD MGGTCAGGGTGACCTRDBHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Ar Original Motif Original Motif MGGTBAVGCTKVMCTGBBMD HWDAGHACRHHVTGTHCCHVMV HHDRKHACRBHVHSHWSBBVHV Direction: Forward Position #: 2 Overlap #: 20 Alignment: -MGGTBAVGCTKVMCTGBBMD- HWDAGHACRHHVTGTHCCHVMV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rsyAGrkGGCGCCmyCTrsy Reverse Complement Reverse Complement VHVBBSWHSHVHBMGTDYMHHH HSKAGKYGGCGCCRMCTMSD HSBDGKBDGCDCMRMSTVBHHHH Direction: Forward Position #: 2 Overlap #: 19 Alignment: -VHVBBSWHSHVHBMGTDYMHHH HSKAGKYGGCGCCRMCTMSD--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- znf143 Combined Motif Reverse Complement Original Motif HHDDBBASRMRGHGCHBYCDVSH BAHYTCCCAKMATGCMWYGC BAHBBYMCABVRTGCMDYSHVSH Direction: Forward Position #: 1 Overlap #: 20 Alignment: HHDDBBASRMRGHGCHBYCDVSH BAHYTCCCAKMATGCMWYGC--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CTCF Combined Motif Reverse Complement Reverse Complement HSBDSMDRGCAMBVTGRKVVHTB BMSMGCCYMCTKSTGGMHM HSBDBMVVGCCCHCTGGKGGHHV Direction: Forward Position #: 5 Overlap #: 19 Alignment: HSBDSMDRGCAMBVTGRKVVHTB ----BMSMGCCYMCTKSTGGMHM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 110 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PLAG1 Zfp423 Original Motif Original Motif GGGGCCCAAGGGGG GSMMCCYARGGKKKC GGSVCCYARGGGGGC Direction: Forward Position #: 1 Overlap #: 14 Alignment: GGGGCCCAAGGGGG- GSMMCCYARGGKKKC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CasCAGrGGGCrsy Original Motif Reverse Complement GGSVCCYARGGGGGC BSKGCCCKCTGGTG GSBGCCCWCKGGKGC Direction: Forward Position #: 1 Overlap #: 14 Alignment: GGSVCCYARGGGGGC BSKGCCCKCTGGTG- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif gwGGCCAGmAGAGGGCrby Original Motif Reverse Complement GSBGCCCWCKGGKGC KBKGCCCTCTYCTGGCCHV GSKGCCCTCTBSTGSCCHV Direction: Forward Position #: 1 Overlap #: 15 Alignment: GSBGCCCWCKGGKGC---- KBKGCCCTCTYCTGGCCHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wgGCCAshAGrGGGCrsy Original Motif Reverse Complement GSKGCCCTCTBSTGSCCHV KBKGCCCKCTHGTGGCHH KSKGCCCTCTBSTGGCCHV Direction: Forward Position #: 1 Overlap #: 18 Alignment: GSKGCCCTCTBSTGSCCHV KBKGCCCKCTHGTGGCHH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Original Motif Reverse Complement KSKGCCCTCTBSTGGCCHV BMSMGCCYMCTKSTGGMHM BVSBGCCCHCTDSTGGCCHV Direction: Forward Position #: 2 Overlap #: 18 Alignment: -KSKGCCCTCTBSTGGCCHV BMSMGCCYMCTKSTGGMHM- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 111 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARG Ar Reverse Complement Original Motif ABTMGGTCACBGTGACCTAS HWDAGHACRHHVTGTHCCHVMV HWARKMRSDCACHGTVMCCKAV Direction: Forward Position #: 3 Overlap #: 20 Alignment: --ABTMGGTCACBGTGACCTAS HWDAGHACRHHVTGTHCCHVMV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rsyAGrkGGCGCCmyCTrsy Combined Motif Original Motif Original Motif HWARKMRSDCACHGTVMCCKAV DSYAGRKGGCGCCMYCTRSH HWADBHAGDBRGYGYBMCCTASH Direction: Forward Position #: 4 Overlap #: 19 Alignment: HWARKMRSDCACHGTVMCCKAV- ---DSYAGRKGGCGCCMYCTRSH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR2 Reverse Complement Original Motif HSTAGGYBKCKCMVDCTDBDTWH VHRGGTCABDBTGMCCTB HVDRGKCABVKYVVBCTDBDTWH Direction: Forward Position #: 1 Overlap #: 18 Alignment: HSTAGGYBKCKCMVDCTDBDTWH VHRGGTCABDBTGMCCTB----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Original Motif Reverse Complement HVDRGKCABVKYVVBCTDBDTWH MGGTCAGGGTGACCTRDBHV MGGTCADGGTSACCKBVVHCTDBDTWH Direction: Forward Position #: 5 Overlap #: 16 Alignment: ----HVDRGKCABVKYVVBCTDBDTWH MGGTCAGGGTGACCTRDBHV------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Original Motif Original Motif MGGTCADGGTSACCKBVVHCTDBDTWH DGVBCABTGDWGCGKRRCSR VGGBCAVBGDDGCSKVRCVVTDBDTWH Direction: Forward Position #: 1 Overlap #: 20 Alignment: MGGTCADGGTSACCKBVVHCTDBDTWH DGVBCABTGDWGCGKRRCSR------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 112 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RELA NF-kappaB Reverse Complement Reverse Complement GGAAATKCCC GGMAAYKCCC GGAAATKCCC Direction: Forward Position #: 1 Overlap #: 10 Alignment: GGAAATKCCC GGMAAYKCCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NFKB1 Reverse Complement Original Motif GGGRATTTCC GGGGRTTCCCC GGGRATTYCCC Direction: Forward Position #: 1 Overlap #: 10 Alignment: GGGRATTTCC- GGGGRTTCCCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TP53 Reverse Complement Original Motif GGGKAATMCCC MSGGACATGYCCGGGCATGT MGGGRMATSCCCGGGCATGT Direction: Forward Position #: 2 Overlap #: 11 Alignment: -GGGKAATMCCC-------- MSGGACATGYCCGGGCATGT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Reverse Complement Original Motif ACATGCCCGGGSATRKCCCR TTCAGCACCATGGACAGCKCC TWCAKSMCCRKGGAYAGCVCV Direction: Forward Position #: 2 Overlap #: 20 Alignment: -ACATGCCCGGGSATRKCCCR TTCAGCACCATGGACAGCKCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGGCrsTGCrs Reverse Complement Original Motif VGVGCTMTCCYMGGYSYTGWA VVGGCRSTGCVB VVGGCKCTSCBVGGYSYTGWA Direction: Forward Position #: 1 Overlap #: 12 Alignment: VGVGCTMTCCYMGGYSYTGWA VVGGCRSTGCVB--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 113 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- REST Ar Reverse Complement Reverse Complement GGYGCTGTCCATGGTGCTGAA VRVDGGHACAVDDKGTHCTDWH GVHGSTRYMCDDKGTBCTKAHV Direction: Backward Position #: 1 Overlap #: 21 Alignment: -GGYGCTGTCCATGGTGCTGAA VRVDGGHACAVDDKGTHCTDWH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- znf143 Combined Motif Original Motif Reverse Complement GVHGSTRYMCDDKGTBCTKAHV GCMWRGCATYRTGGGAMHTB GVHGCWDBSCATKGTGSKDAHBB Direction: Forward Position #: 4 Overlap #: 19 Alignment: GVHGSTRYMCDDKGTBCTKAHV- ---GCMWRGCATYRTGGGAMHTB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- gwGGCCAGmAGAGGGCrby Combined Motif Original Motif Original Motif GVHGCWDBSCATKGTGSKDAHBB VHGGCCAGMAGAGGGCRBY GVHGSCCAGMAGDGKGCDVHHBB Direction: Forward Position #: 2 Overlap #: 19 Alignment: GVHGCWDBSCATKGTGSKDAHBB -VHGGCCAGMAGAGGGCRBY--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rgyGCCMyCTksTGGccd Combined Motif Reverse Complement Reverse Complement BVHDVHGCYCDCTRCTGGSCHVC DDGCCASYAGMGGGCKVM BVHDDVGCCMBYWGMDGGCBHVC Direction: Forward Position #: 5 Overlap #: 18 Alignment: BVHDVHGCYCDCTRCTGGSCHVC ----DDGCCASYAGMGGGCKVM- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asmAGRGGGCrCTGsmkc Original Motif Reverse Complement BVHDDVGCCMBYWGMDGGCBHVC DBTSCAGMGCCCTCTRST DBBVCAGMGCCCKCTGCDGGCBHVC Direction: Forward Position #: 3 Overlap #: 16 Alignment: --BVHDDVGCCMBYWGMDGGCBHVC DBTSCAGMGCCCTCTRST------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 114 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RUNX1 Ar Original Motif Reverse Complement BBYTGTGGTTT VRVDGGHACAVDDKGTHCTDWH DKGTHCTDWHDBBKGTRSHBDV Direction: Backward Position #: 11 Overlap #: 11 Alignment: -BBYTGTGGTTT---------- VRVDGGHACAVDDKGTHCTDWH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif HNF4A Reverse Complement Original Motif VDVHSMACRBBHHWDAGHACRH RGGBCAAAGKYCA VGDHCAAMRKBCAWDAGHACRH Direction: Forward Position #: 1 Overlap #: 13 Alignment: VDVHSMACRBBHHWDAGHACRH RGGBCAAAGKYCA--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wgGCCAshAGrGGGCrsy Reverse Complement Reverse Complement DKGTHCTDWTGVYMRTTGHHCV KBKGCCCKCTHGTGGCHH KBKGYCCTCTHGHGSVHHGHHCV Direction: Forward Position #: 2 Overlap #: 17 Alignment: -DKGTHCTDWTGVYMRTTGHHCV KBKGCCCKCTHGTGGCHH----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- INSM1 Combined Motif Original Motif Reverse Complement KBKGYCCTCTHGHGSVHHGHHCV MGCCCCCTGMCA VHGYCCCCTGVCMKBKGYCCTCT Direction: Backward Position #: 2 Overlap #: 12 Alignment: KBKGYCCTCTHGHGSVHHGHHCV ----------MGCCCCCTGMCA- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 115 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RXRRAR_DR5 PPARG Original Motif Original Motif RGKTCABVVRGAGGTCA STAGGTCACBGTGACCYABT STRGGTCABVGWGASSTMAT Direction: Forward Position #: 3 Overlap #: 17 Alignment: --RGKTCABVVRGAGGTCA- STAGGTCACBGTGACCYABT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Reverse Complement Original Motif ATRASSTCWCVBTGACCKAS VDBHMAGGTCACCCTGACCY VDHHVAGGTCACVBTGACCTAS Direction: Forward Position #: 3 Overlap #: 18 Alignment: --ATRASSTCWCVBTGACCKAS VDBHMAGGTCACCCTGACCY-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Reverse Complement Reverse Complement STAGGTCABVGTGACCTBHHHV BAGGYCABHBTGACCKHV STAGGTCABBBTGACCTBVHHV Direction: Forward Position #: 2 Overlap #: 18 Alignment: STAGGTCABVGTGACCTBHHHV -BAGGYCABHBTGACCKHV--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Pax5 Reverse Complement Original Motif VDHBVAGGTCABBBTGACCTAS DGVBCABTGDWGCGKRRCSR DRVBHABKKVAGVGTRACCDAS Direction: Forward Position #: 1 Overlap #: 20 Alignment: VDHBVAGGTCABBBTGACCTAS DGVBCABTGDWGCGKRRCSR-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- gwGGCCAGmAGAGGGCrby Combined Motif Reverse Complement Reverse Complement STDGGTMACVCTVRYBTDBBMH KBKGCCCTCTYCTGGCCHV STDGKGCMCKCTBVTGKVCHHH Direction: Forward Position #: 3 Overlap #: 19 Alignment: STDGGTMACVCTVRYBTDBBMH --KBKGCCCTCTYCTGGCCHV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 116 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- SP1 csCSCCdCCCcs Original Motif Original Motif CCCCKCCCCC VBCCCCDCCCHV VBCCCCDCCCCC Direction: Forward Position #: 3 Overlap #: 10 Alignment: --CCCCKCCCCC VBCCCCDCCCHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rsyAGrkGGCGCCmyCTrsy Reverse Complement Reverse Complement GGGGGHGGGGBV HSKAGKYGGCGCCRMCTMSD HSKRGGYGGSGCCRMCTMSD Direction: Forward Position #: 2 Overlap #: 12 Alignment: -GGGGGHGGGGBV------- HSKAGKYGGCGCCRMCTMSD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Original Motif Original Motif HSKRGGYGGSGCCRMCTMSD YDRCCASYAGRKGGCRSYV YDDCCAGBAGGBGSCRCCDMSD Direction: Forward Position #: 3 Overlap #: 17 Alignment: --HSKRGGYGGSGCCRMCTMSD YDRCCASYAGRKGGCRSYV--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif myrGYGCCmCCTast Reverse Complement Reverse Complement DSYDGGMGSCBCCTBCTGGDHM ASTAGGYGGCGCTBB DSTAGGHGGCBCYBBCTGGDHM Direction: Forward Position #: 1 Overlap #: 15 Alignment: DSYDGGMGSCBCCTBCTGGDHM ASTAGGYGGCGCTBB------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfx Combined Motif Original Motif Original Motif DSTAGGHGGCBCYBBCTGGDHM BBVGCCBVGGCCTV DSTAGGVGSCBCGGCCTBGDHM Direction: Forward Position #: 5 Overlap #: 14 Alignment: DSTAGGHGGCBCYBBCTGGDHM ----BBVGCCBVGGCCTV---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 117 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spz1 AgmAGAGGGCrscAGak Reverse Complement Reverse Complement GCTGWTACCCT RTCTGSTGCCCTCTYCT CTYCTBCTGBTRCCCTR Direction: Backward Position #: 6 Overlap #: 11 Alignment: -GCTGWTACCCT----- RTCTGSTGCCCTCTYCT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asyAGrkGGCRGCAga Reverse Complement Original Motif KAGGGMAVCAGBAGMAG ASYAGRKGGCAGCABH ABHRGGBRGCAGCAVMAG Direction: Forward Position #: 2 Overlap #: 15 Alignment: -KAGGGMAVCAGBAGMAG ASYAGRKGGCAGCABH-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Original Motif Reverse Complement ABHRGGBRGCAGCAVMAG VRVDGGHACAVDDKGTHCTDWH ABHRGVBGGCASMADDWGTHCTDWH Direction: Forward Position #: 4 Overlap #: 15 Alignment: ABHRGGBRGCAGCAVMAG------- ---VRVDGGHACAVDDKGTHCTDWH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Original Motif Original Motif ABHRGVBGGCASMADDWGTHCTDWH VDBHMAGGTCACCCTGACCY VBVVVRGGKCASHVTGASYYCTDWH Direction: Forward Position #: 1 Overlap #: 20 Alignment: ABHRGVBGGCASMADDWGTHCTDWH VDBHMAGGTCACCCTGACCY----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Tcfcp2l1 Combined Motif Original Motif Reverse Complement VBVVVRGGKCASHVTGASYYCTDWH CKGGDTBDMMCTGG VBVVCDGGKYDBMMYKRGYYCTDWH Direction: Forward Position #: 5 Overlap #: 14 Alignment: VBVVVRGGKCASHVTGASYYCTDWH ----CKGGDTBDMMCTGG------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 118 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- SRF wgGCCAshAGrGGGCrsy Reverse Complement Reverse Complement CCATATATGGGC KBKGCCCKCTHGTGGCHH HHCCHTMTABKGGCKBKG Direction: Backward Position #: 3 Overlap #: 12 Alignment: ----CCATATATGGGC-- KBKGCCCKCTHGTGGCHH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif gwGGCCAGmAGAGGGCrby Original Motif Reverse Complement HHCCHTMTABKGGCKBKG KBKGCCCTCTYCTGGCCHV KBBGCCCTCTHBTGGCBBBG Direction: Forward Position #: 3 Overlap #: 17 Alignment: --HHCCHTMTABKGGCKBKG KBKGCCCTCTYCTGGCCHV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rgyGCCMyCTksTGGccd Original Motif Original Motif KBBGCCCTCTHBTGGCBBBG RVYGCCCYCTKSTGGCHD DBYGCCCTCTDSTGGCBDBG Direction: Forward Position #: 1 Overlap #: 18 Alignment: KBBGCCCTCTHBTGGCBBBG RVYGCCCYCTKSTGGCHD-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Reverse Complement Reverse Complement CVDBGCCASDAGAGGGCKBH BMSMGCCYMCTKSTGGMHM CVVVGCCHVCWGVKGGCBVH Direction: Forward Position #: 1 Overlap #: 19 Alignment: CVDBGCCASDAGAGGGCKBH BMSMGCCYMCTKSTGGMHM- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 67 Combined Motif Reverse Complement Reverse Complement DVBGCCRBCWGVHGGCVVBG CCASHAGKGGGCKS DVBGCCASCAGGDGGCDVBG Direction: Forward Position #: 5 Overlap #: 14 Alignment: DVBGCCRBCWGVHGGCVVBG ----CCASHAGKGGGCKS-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 119 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stat3 ELK1 Reverse Complement Reverse Complement CTTCCTGGAA MTTCCGGHBV MTTCCKGGDA Direction: Backward Position #: 1 Overlap #: 10 Alignment: CTTCCTGGAA MTTCCGGHBV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif EBF1 Original Motif Original Motif MTTCCKGGDA MCCCMAGGGA MYYCCRGGGA Direction: Forward Position #: 1 Overlap #: 10 Alignment: MTTCCKGGDA MCCCMAGGGA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif INSM1 Original Motif Reverse Complement MYYCCRGGGA MGCCCCCTGMCA MBYCCVSDGACA Direction: Forward Position #: 1 Overlap #: 10 Alignment: MYYCCRGGGA-- MGCCCCCTGMCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Reverse Complement Original Motif TGTCHSVGGKVR YDRCCASYAGRKGGCRSYV YKGYCASBRGGDGGCRSYV Direction: Forward Position #: 2 Overlap #: 12 Alignment: -TGTCHSVGGKVR------ YDRCCASYAGRKGGCRSYV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TP53 Original Motif Reverse Complement YKGYCASBRGGDGGCRSYV ACATGCCCGGKCATGTCCSR ACATGCCCGGKCATGTCMSVRGGDGGCRSYV Direction: Forward Position #: 13 Overlap #: 8 Alignment: ------------YKGYCASBRGGDGGCRSYV ACATGCCCGGKCATGTCCSR----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 120 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- T ctCTrsyGCCmCCTast Reverse Complement Original Motif TTCACACCTAG HDCTGSYGCCMCCTAST HDCTGBTSMCACCTAGT Direction: Forward Position #: 6 Overlap #: 11 Alignment: -----TTCACACCTAG- HDCTGSYGCCMCCTAST ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asyAGrkGGCRGCAga Reverse Complement Original Motif ACTAGGTGRSAVCAGDD ASYAGRKGGCAGCABH ASTAGGTGGCAVCAGDD Direction: Forward Position #: 1 Overlap #: 16 Alignment: ACTAGGTGRSAVCAGDD ASYAGRKGGCAGCABH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif myrGYGCCmCCTast Original Motif Reverse Complement ASTAGGTGGCAVCAGDD ASTAGGYGGCGCTBB ASTAGGTGGCRCBABDD Direction: Forward Position #: 1 Overlap #: 15 Alignment: ASTAGGTGGCAVCAGDD ASTAGGYGGCGCTBB-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Original Motif Original Motif ASTAGGTGGCRCBABDD YDRCCASYAGRKGGCRSYV YDDCYAGBWGGSGSCRBHV Direction: Forward Position #: 3 Overlap #: 17 Alignment: --ASTAGGTGGCRCBABDD YDRCCASYAGRKGGCRSYV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PPARG Reverse Complement Original Motif VHBKGSCSCCWBCTKGDHM STAGGTCACBGTGACCYABT STAGGTCACVDTGVCCBMCTBCTKGDHM Direction: Forward Position #: 10 Overlap #: 11 Alignment: ---------VHBKGSCSCCWBCTKGDHM STAGGTCACBGTGACCYABT-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 121 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TAL1TCF3 asCAGrkGGCrsy Reverse Complement Original Motif ARCAGATGRTVD ASCAGRGGGCRSB AVCAGRKGGYVVB Direction: Forward Position #: 1 Overlap #: 12 Alignment: ARCAGATGRTVD- ASCAGRGGGCRSB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CasCAGrGGGCrsy Reverse Complement Reverse Complement BVVKCCRKCTGVT BSKGCCCKCTGGTG BVBGCCVKCTGSTG Direction: Forward Position #: 1 Overlap #: 13 Alignment: BVVKCCRKCTGVT- BSKGCCCKCTGGTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NFYA Original Motif Original Motif BVBGCCVKCTGSTG VBBRRCCAATSRGVDB VBBDGCCAWYYGSHGB Direction: Forward Position #: 2 Overlap #: 14 Alignment: -BVBGCCVKCTGSTG- VBBRRCCAATSRGVDB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- agrCCAGmAGrg Combined Motif Reverse Complement Reverse Complement BCHSCMMWTGGCHBVV CKCTRCTGGCVH BCDCYRCTKGSCHBVV Direction: Forward Position #: 2 Overlap #: 12 Alignment: BCHSCMMWTGGCHBVV -CKCTRCTGGCVH--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AgmAGAGGGCrscAGak Reverse Complement Original Motif VBBHGSCYAGKMGDGB AGMAGAGGGCASCAGAK AGMAGAGGSCAGBAGAKB Direction: Forward Position #: 3 Overlap #: 15 Alignment: --VBBHGSCYAGKMGDGB AGMAGAGGGCASCAGAK- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 122 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Tcfcp2l1 rsyAGrkGGCGCCmyCTrsy Reverse Complement Original Motif CKGGDTBDMMCTGG DSYAGRKGGCGCCMYCTRSH DSYAGSKGGBKCBMHCTGGH Direction: Forward Position #: 6 Overlap #: 14 Alignment: -----CKGGDTBDMMCTGG- DSYAGRKGGCGCCMYCTRSH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Reverse Complement Reverse Complement HCCAGDYBGYBCCRSCTMSD VRVDGGHACAVDDKGTHCTDWH HCCAGRHBGBDMCASBTHGTHCTDWH Direction: Forward Position #: 5 Overlap #: 16 Alignment: HCCAGDYBGYBCCRSCTMSD------ ----VRVDGGHACAVDDKGTHCTDWH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ctCTrsyGCCmCCTast Combined Motif Reverse Complement Reverse Complement HWDAGHACHABSTGRDBCBDMCTGGH ASTAGGYGGCMSCAGDD HWDAGAVBAGGBGGCMSCAGHVTGGH Direction: Forward Position #: 6 Overlap #: 17 Alignment: HWDAGHACHABSTGRDBCBDMCTGGH -----ASTAGGYGGCMSCAGDD---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Reverse Complement Reverse Complement HCCAVHCTGSYGCCBCCTBBTCTDWH MGGTCAGGGTGACCTRDBHV MSSWCABBGBBRCCKVVBBBTCTDWH Direction: Forward Position #: 1 Overlap #: 20 Alignment: HCCAVHCTGSYGCCBCCTBBTCTDWH MGGTCAGGGTGACCTRDBHV------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfx Combined Motif Reverse Complement Original Motif HWDAGABVVVVRGGKBVCVBTGWSSY BBVGCCBVGGCCTV HWDAGVBVVSCDVGGCCYVBTGWSSY Direction: Forward Position #: 6 Overlap #: 14 Alignment: HWDAGABVVVVRGGKBVCVBTGWSSY -----BBVGCCBVGGCCTV------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 123 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TFAP2A Zfx Original Motif Reverse Complement GCCBBVRGS VAGGCCBBGGCVBB BBGCCBBGGSSVAG Direction: Backward Position #: 3 Overlap #: 9 Alignment: ---GCCBBVRGS-- VAGGCCBBGGCVBB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rgCGCCmyCTgs Original Motif Original Motif BBGCCBBGGSSVAG VGCGCCCYCTDS VBCGCCHYSKVSVAG Direction: Forward Position #: 2 Overlap #: 11 Alignment: -BBGCCBBGGSSVAG VGCGCCCYCTDS--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TLX1NFIC Original Motif Reverse Complement VBCGCCHYSKVSVAG TTGGCHDBSTGCCA TTSGCCBBSTGCCAG Direction: Forward Position #: 1 Overlap #: 14 Alignment: VBCGCCHYSKVSVAG TTGGCHDBSTGCCA- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asCAGrkGGCrsy Original Motif Reverse Complement TTSGCCBBSTGCCAG BSKGCCCMCTGST DBKGCCYVCTGCBAG Direction: Forward Position #: 1 Overlap #: 13 Alignment: TTSGCCBBSTGCCAG BSKGCCCMCTGST-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif scAGrkGGCGcy Original Motif Reverse Complement DBKGCCYVCTGCBAG VGCGCCCMCTDS HBCGCCYMCTGSBAG Direction: Forward Position #: 1 Overlap #: 12 Alignment: DBKGCCYVCTGCBAG VGCGCCCMCTDS--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 124 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TLX1NFIC ESR1 Original Motif Original Motif TGGCASBDHGCCAA VDBHMAGGTCACCCTGACCY VDBHMAKGKCASCVTGMCMW Direction: Forward Position #: 7 Overlap #: 14 Alignment: ------TGGCASBDHGCCAA VDBHMAGGTCACCCTGACCY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- znf143 Combined Motif Reverse Complement Reverse Complement WYGRCAVGSTGYCRTRDBHV GCMWRGCATYRTGGGAMHTB WYGRCADRGYRYCRTGGGHVHTB Direction: Forward Position #: 4 Overlap #: 17 Alignment: WYGRCAVGSTGYCRTRDBHV--- ---GCMWRGCATYRTGGGAMHTB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR2 Reverse Complement Reverse Complement BAHBHCCCAKGMMMCMDTGMCMW BAGGYCABHBTGACCKHV BADKHCMCHBKGAMCBHDGMCMW Direction: Forward Position #: 1 Overlap #: 18 Alignment: BAHBHCCCAKGMMMCMDTGMCMW BAGGYCABHBTGACCKHV----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PPARG Original Motif Original Motif BADKHCMCHBKGAMCBHDGMCMW STAGGTCACBGTGACCYABT STAGGTCACVGTGACCBABKMCMW Direction: Forward Position #: 2 Overlap #: 19 Alignment: -BADKHCMCHBKGAMCBHDGMCMW STAGGTCACBGTGACCYABT---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Original Motif Original Motif STAGGTCACVGTGACCBABKMCMW TTCAGCACCATGGACAGCKCC BTMRGYMMCHBKGACMGHDBCCMW Direction: Forward Position #: 1 Overlap #: 21 Alignment: STAGGTCACVGTGACCBABKMCMW TTCAGCACCATGGACAGCKCC--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 125 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TP53 gwGGCCAGmAGAGGGCrby Reverse Complement Reverse Complement ACATGCCCGGKCATGTCCSR KBKGCCCTCTYCTGGCCHV BDTGCCCKSTCMTGKCCVVA Direction: Backward Position #: 1 Overlap #: 19 Alignment: ACATGCCCGGKCATGTCCSR -KBKGCCCTCTYCTGGCCHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif znf143 Original Motif Original Motif BDTGCCCKSTCMTGKCCVVA BAHYTCCCAKMATGCMWYGC BATGYCCSVKCMTGSMHHGM Direction: Forward Position #: 1 Overlap #: 20 Alignment: BDTGCCCKSTCMTGKCCVVA BAHYTCCCAKMATGCMWYGC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR2 Reverse Complement Original Motif YCHDRSCAYGRBSGGKCATB VHRGGTCABDBTGMCCTB BHVGGKCABDRTGRSBYVTB Direction: Forward Position #: 1 Overlap #: 18 Alignment: YCHDRSCAYGRBSGGKCATB VHRGGTCABDBTGMCCTB-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfx Combined Motif Original Motif Reverse Complement BHVGGKCABDRTGRSBYVTB VAGGCCBBGGCVBB BHVRGGCMBBGBSVBBYVTB Direction: Forward Position #: 3 Overlap #: 14 Alignment: BHVGGKCABDRTGRSBYVTB --VAGGCCBBGGCVBB---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Tcfcp2l1 Combined Motif Reverse Complement Original Motif BABMBBVSBCBVRGCCKBDB CCAGYYHVADCCRG BABMCCVGYYBVRGCCDGDB Direction: Forward Position #: 5 Overlap #: 14 Alignment: BABMBBVSBCBVRGCCKBDB ----CCAGYYHVADCCRG-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 126 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- USF1 MAX Original Motif Reverse Complement CACGTGR BCACGTGDTD BCMMSKKGKD Direction: Forward Position #: 3 Overlap #: 7 Alignment: --CACGTGR- BCACGTGDTD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif MYCMAX Original Motif Reverse Complement BCMMSKKGKD ACCACGTGSTM HCCACGTGBKM Direction: Forward Position #: 1 Overlap #: 10 Alignment: BCMMSKKGKD- ACCACGTGSTM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Myc Original Motif Reverse Complement HCCACGTGBKM DCCACGTGCV DCCACGTGVDM Direction: Forward Position #: 1 Overlap #: 10 Alignment: HCCACGTGBKM DCCACGTGCV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Mycn Original Motif Reverse Complement DCCACGTGVDM GCCACGTGSD DCCACGTGSDM Direction: Forward Position #: 1 Overlap #: 10 Alignment: DCCACGTGVDM GCCACGTGSD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif HIF1AARNT Reverse Complement Original Motif RHSCACGTGGH VBACGTGV VBRCRYGYGGH Direction: Forward Position #: 1 Overlap #: 8 Alignment: RHSCACGTGGH VBACGTGV--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 127 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- YY1 Motif 61 Original Motif Reverse Complement RCCATB KCCATCT KCCMWYT Direction: Forward Position #: 2 Overlap #: 6 Alignment: -RCCATB KCCATCT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 12 Original Motif Reverse Complement KCCMWYT GAGCCATC GAGCCATCT Direction: Forward Position #: 3 Overlap #: 6 Alignment: --KCCMWYT GAGCCATC- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- grCCACyAGAkG Combined Motif Original Motif Original Motif GAGCCATCT DDCCACYAGAKG GAGCCAYYWGAKG Direction: Forward Position #: 2 Overlap #: 8 Alignment: GAGCCATCT---- -DDCCACYAGAKG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Original Motif Original Motif GAGCCAYYWGAKG YDRCCASYAGRKGGCRSYV KDGCCACYAGAKGGCRSYV Direction: Forward Position #: 1 Overlap #: 13 Alignment: GAGCCAYYWGAKG------ YDRCCASYAGRKGGCRSYV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- grCCACyAGAkG Combined Motif Original Motif Original Motif KDGCCACYAGAKGGCRSYV DDCCACYAGAKG KDDCCACYAGAKGGCRSYV Direction: Forward Position #: 2 Overlap #: 12 Alignment: KDGCCACYAGAKGGCRSYV -DDCCACYAGAKG------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 128 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ZEB1 T Original Motif Reverse Complement CACCTD TTCACACCTAG TYMMCWCCTAG Direction: Forward Position #: 2 Overlap #: 6 Alignment: -CACCTD---- TTCACACCTAG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif myrGYGCCmCCTast Reverse Complement Reverse Complement CTAGGWGRYMA ASTAGGYGGCGCTBB ACTAGGTGGCVMTBB Direction: Forward Position #: 2 Overlap #: 11 Alignment: -CTAGGWGRYMA--- ASTAGGYGGCGCTBB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Reverse Complement Reverse Complement VBARVGCCACCTAGT BMSMGCCYMCTKSTGGMHM BMVHRVCBCCWBCTRGHHM Direction: Forward Position #: 3 Overlap #: 15 Alignment: --VBARVGCCACCTAGT-- BMSMGCCYMCTKSTGGMHM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asyAGrkGGCRGCAga Original Motif Reverse Complement BMVHRVCBCCWBCTRGHHM HBTGCTGCCYMCTKST HBTVSBGCCYCCTBSTRGHHM Direction: Forward Position #: 3 Overlap #: 14 Alignment: --BMVHRVCBCCWBCTRGHHM HBTGCTGCCYMCTKST----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ctCTrsyGCCmCCTast Original Motif Original Motif HBTVSBGCCYCCTBSTRGHHM HDCTGSYGCCMCCTAST HDCTRSYGCCHCCTDSTRGHHM Direction: Forward Position #: 2 Overlap #: 16 Alignment: -HBTVSBGCCYCCTBSTRGHHM HDCTGSYGCCMCCTAST----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 129 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfp423 NFYA Reverse Complement Reverse Complement GYRYCCMTKGGYRSC BHVCKSATTGGMKBVV RBRCYCATTGGYDSMV Direction: Forward Position #: 1 Overlap #: 15 Alignment: GYRYCCMTKGGYRSC- BHVCKSATTGGMKBVV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Reverse Complement Reverse Complement VRSHKCCAATGKGMBM BMSMGCCYMCTKSTGGMHM BVSMGCCHMYKKGHGSMHM Direction: Forward Position #: 1 Overlap #: 16 Alignment: VRSHKCCAATGKGMBM--- BMSMGCCYMCTKSTGGMHM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rgyGCCMyCTksTGGccd Combined Motif Original Motif Reverse Complement BVSMGCCHMYKKGHGSMHM DDGCCASYAGMGGGCKVM BVBVGCCAVYDGVDGGCBVM Direction: Forward Position #: 3 Overlap #: 17 Alignment: BVSMGCCHMYKKGHGSMHM- --DDGCCASYAGMGGGCKVM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Original Motif Original Motif BVBVGCCAVYDGVDGGCBVM HWDAGHACRHHVTGTHCCHVMV BVHHDMSAACABVVKGYHCCHVMV Direction: Forward Position #: 3 Overlap #: 18 Alignment: BVBVGCCAVYDGVDGGCBVM---- --HWDAGHACRHHVTGTHCCHVMV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Original Motif Reverse Complement BVHHDMSAACABVVKGYHCCHVMV MSGKKRCGCWDCABTGBBCD HVGDKVCVCHDBVVBGYBCHHVMV Direction: Forward Position #: 1 Overlap #: 20 Alignment: BVHHDMSAACABVVKGYHCCHVMV MSGKKRCGCWDCABTGBBCD---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 130 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfx asmAGRGGGCrCTGsmkc Original Motif Reverse Complement BBVGCCBVGGCCTV DBTSCAGMGCCCTCTRST BBBGCMGMGSCCTCTRST Direction: Forward Position #: 1 Overlap #: 14 Alignment: BBVGCCBVGGCCTV---- DBTSCAGMGCCCTCTRST ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Reverse Complement Reverse Complement ASMAGAGGSCRCYGCVBB MSGKKRCGCWDCABTGBBCD ASMASRGGVCGCHKCVBBGBBCD Direction: Forward Position #: 4 Overlap #: 15 Alignment: ASMAGAGGSCRCYGCVBB----- ---MSGKKRCGCWDCABTGBBCD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Reverse Complement Reverse Complement HGVBCVBBGYHGCGVCCKSTRST BAGGYCABHBTGACCKHV HGVVVDBCRBHGYGACCKBBRST Direction: Forward Position #: 3 Overlap #: 18 Alignment: HGVBCVBBGYHGCGVCCKSTRST --BAGGYCABHBTGACCKHV--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TP53 Combined Motif Reverse Complement Original Motif ASMVBRGGTCMCHBKGVHVBVCD MSGGACATGYCCGGGCATGT ASMVBRGGTCMCHBKGVVGDRCATGYCCGGGCATGT Direction: Forward Position #: 17 Overlap #: 7 Alignment: ASMVBRGGTCMCHBKGVHVBVCD------------- ----------------MSGGACATGYCCGGGCATGT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yrcrGYGCCMyCTGGtG Original Motif Reverse Complement ASMVBRGGTCMCHBKGVVGDRCATGYCCGGGCATGT CACCAGMGGGCGCTGBD CASCAGAGGGCDCBGBDVVGDRCATGYCCGGGCATGT Direction: Forward Position #: 2 Overlap #: 16 Alignment: -ASMVBRGGTCMCHBKGVVGDRCATGYCCGGGCATGT CACCAGMGGGCGCTGBD-------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 131 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- znf143 Ar Reverse Complement Reverse Complement GCMWRGCATYRTGGGAMHTB VRVDGGHACAVDDKGTHCTDWH GVHDGGYACHRTGGGWHCTBWH Direction: Forward Position #: 1 Overlap #: 20 Alignment: GCMWRGCATYRTGGGAMHTB-- VRVDGGHACAVDDKGTHCTDWH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Reverse Complement Reverse Complement HWVAGHWCCCAMHGTKCCDHVC MSGKKRCGCWDCABTGBBCD HHVRKBACBCWDHVTDSHDMDC Direction: Forward Position #: 2 Overlap #: 20 Alignment: HWVAGHWCCCAMHGTKCCDHVC -MSGKKRCGCWDCABTGBBCD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- REST Combined Motif Original Motif Reverse Complement HHVRKBACBCWDHVTDSHDMDC GGYGCTGTCCATGGTGCTGAA HHVRKBACBCDVHGCTSYCCVHGGTGCTGAA Direction: Forward Position #: 11 Overlap #: 12 Alignment: HHVRKBACBCWDHVTDSHDMDC--------- ----------GGYGCTGTCCATGGTGCTGAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TP53 Combined Motif Original Motif Reverse Complement HHVRKBACBCDVHGCTSYCCVHGGTGCTGAA ACATGCCCGGKCATGTCCSR HHAVRTRCCCGGBCMTGTCCVVGGTGCTGAA Direction: Forward Position #: 3 Overlap #: 20 Alignment: HHVRKBACBCDVHGCTSYCCVHGGTGCTGAA --ACATGCCCGGKCATGTCCSR--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Original Motif Original Motif HHAVRTRCCCGGBCMTGTCCVVGGTGCTGAA VDBHMAGGTCACCCTGACCY VHVVVWGSBCRSBCWKRYCYVVGGTGCTGAA Direction: Forward Position #: 1 Overlap #: 20 Alignment: HHAVRTRCCCGGBCMTGTCCVVGGTGCTGAA VDBHMAGGTCACCCTGACCY----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 132 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ZNF354C grCCACyAGAkG Reverse Complement Reverse Complement GTGGAY CYTCTKGTGGHH CYTCTKGTGGHB Direction: Forward Position #: 7 Overlap #: 6 Alignment: ------GTGGAY CYTCTKGTGGHH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif grCCACwAGrk Reverse Complement Original Motif BHCCACYAGAKG DDCCACWAGRK BDCCACTAGAKG Direction: Forward Position #: 1 Overlap #: 11 Alignment: BHCCACYAGAKG DDCCACWAGRK- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif grCCACyAGAkG Reverse Complement Reverse Complement CYTCTAGTGGDB CYTCTMGTGGHH CYTCTMGTGGHB Direction: Forward Position #: 1 Overlap #: 12 Alignment: CYTCTAGTGGDB CYTCTMGTGGHH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RUNX1 Reverse Complement Reverse Complement BHCCACYAGAKG AAACCACAKVB DHMCMMCAGABG Direction: Forward Position #: 1 Overlap #: 11 Alignment: BHCCACYAGAKG AAACCACAKVB- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 9 Original Motif Reverse Complement DHMCMMCAGABG SWGCCACC SDGCCACCAGABG Direction: Forward Position #: 2 Overlap #: 7 Alignment: -DHMCMMCAGABG SWGCCACC----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 133 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- shAGrGGGCAgy wgGCCAshAGrGGGCrsy Original Motif Original Motif SHAGRGGGCABH HDGCCACHAGRGGGCRBY HDGCCASHAGRGGGCABH Direction: Forward Position #: 7 Overlap #: 12 Alignment: ------SHAGRGGGCABH HDGCCACHAGRGGGCRBY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- AgmAGAGGGCrscAGak Combined Motif Original Motif Original Motif HDGCCASHAGRGGGCABH AGMAGAGGGCASCAGAK HDGCCASMAGAGGGCASYAGAK Direction: Forward Position #: 6 Overlap #: 13 Alignment: HDGCCASHAGRGGGCABH---- -----AGMAGAGGGCASCAGAK ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif gwGGCCAGmAGAGGGCrby Original Motif Original Motif HDGCCASMAGAGGGCASYAGAK VHGGCCAGMAGAGGGCRBY VHGGCCAGMAGAGGGCRBYAGAK Direction: Forward Position #: 2 Overlap #: 18 Alignment: -HDGCCASMAGAGGGCASYAGAK VHGGCCAGMAGAGGGCRBY---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CasCAGrGGGCrsy Original Motif Reverse Complement VHGGCCAGMAGAGGGCRBYAGAK BSKGCCCKCTGGTG DVKGCCMKCWGRKGGCRBYAGAK Direction: Forward Position #: 1 Overlap #: 14 Alignment: VHGGCCAGMAGAGGGCRBYAGAK BSKGCCCKCTGGTG--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asCAGrkGGCrsy Original Motif Reverse Complement DVKGCCMKCWGRKGGCRBYAGAK BSKGCCCMCTGST BVKGCCCVCTGVKGGCRBYAGAK Direction: Forward Position #: 1 Overlap #: 13 Alignment: DVKGCCMKCWGRKGGCRBYAGAK BSKGCCCMCTGST---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 134 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGwGCGss ssCGGCCGss Reverse Complement Original Motif VBCGCWCGSB BSCGGCCGSV VBCGSMCGSB Direction: Forward Position #: 1 Overlap #: 10 Alignment: VBCGCWCGSB BSCGGCCGSV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGCwGCGss Original Motif Original Motif VBCGSMCGSB VSCGCDGCGSB VBCGCHSSGBB Direction: Forward Position #: 1 Overlap #: 10 Alignment: VBCGSMCGSB- VSCGCDGCGSB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yrCATGCAyr Original Motif Reverse Complement VBCGCHSSGBB HVTGCATGKV VVYGCAYGKVB Direction: Forward Position #: 1 Overlap #: 10 Alignment: VBCGCHSSGBB HVTGCATGKV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif grCCACwAGrk Original Motif Original Motif VVYGCAYGKVB DDCCACWAGRK DVCCRCWAGDBB Direction: Forward Position #: 2 Overlap #: 10 Alignment: -VVYGCAYGKVB DDCCACWAGRK- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Original Motif Original Motif DVCCRCWAGDBB DGVBCABTGDWGCGKRRCSR DDVHDCAHKGDDGCGKRRCSR Direction: Forward Position #: 2 Overlap #: 11 Alignment: DVCCRCWAGDBB--------- -DGVBCABTGDWGCGKRRCSR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 135 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGGCCGss ssCGwGCGss Reverse Complement Original Motif VSCGGCCGSB BSCGWGCGBV BSCGDSCGBV Direction: Backward Position #: 1 Overlap #: 10 Alignment: VSCGGCCGSB BSCGWGCGBV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ysGTGGCCACsr Original Motif Original Motif BSCGDSCGBV BVGTGGCCACBV BBGYGGCCRCVV Direction: Forward Position #: 2 Overlap #: 10 Alignment: -BSCGDSCGBV- BVGTGGCCACBV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR2 Reverse Complement Original Motif VVGMGGCCKCBB VHRGGTCABDBTGMCCTB VHRVGKCMKBBTGMCCTB Direction: Forward Position #: 1 Overlap #: 12 Alignment: VVGMGGCCKCBB------ VHRGGTCABDBTGMCCTB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PPARG Original Motif Original Motif VHRVGKCMKBBTGMCCTB STAGGTCACBGTGACCYABT VTRGGTCABBGTGACCYVBT Direction: Forward Position #: 1 Overlap #: 18 Alignment: VHRVGKCMKBBTGMCCTB-- STAGGTCACBGTGACCYABT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Reverse Complement Original Motif ABBMGGTCACBBTGACCKAV VDBHMAGGTCACCCTGACCY ABBMGGBCMVGGTSACCBWGACCY Direction: Forward Position #: 5 Overlap #: 16 Alignment: ABBMGGTCACBBTGACCKAV---- ----VDBHMAGGTCACCCTGACCY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 136 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- dwCAGAAGwh agrCCAGmAGrg Original Motif Original Motif DHCAGAAGDH HVGCCAGMAGRG HVRCCAGAAGDB Direction: Forward Position #: 3 Overlap #: 10 Alignment: --DHCAGAAGDH HVGCCAGMAGRG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif raCAAAACam Reverse Complement Reverse Complement BDCTTCTGGMVH HTGTTTTGTD HTSTTYTGDHVH Direction: Forward Position #: 1 Overlap #: 10 Alignment: BDCTTCTGGMVH HTGTTTTGTD-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif grCCACwAGrk Original Motif Reverse Complement HTSTTYTGDHVH YMCTWGTGGHH HHCTTGTGGHHH Direction: Forward Position #: 1 Overlap #: 11 Alignment: HTSTTYTGDHVH YMCTWGTGGHH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif mkCTyTTCsg Original Motif Original Motif HHCTTGTGGHHH HBCTTTTCBD HBCTTTTSGBHH Direction: Forward Position #: 1 Overlap #: 10 Alignment: HHCTTGTGGHHH HBCTTTTCBD-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif gwGGCCAGmAGAGGGCrby Reverse Complement Original Motif HDBCSAAAAGVD VHGGCCAGMAGAGGGCRBY VHGGCCARAAGAGGGCRBY Direction: Forward Position #: 2 Overlap #: 12 Alignment: -HDBCSAAAAGVD------ VHGGCCAGMAGAGGGCRBY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 137 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rgCGCCmyCTgs scAGrkGGCGcy Original Motif Reverse Complement VGCGCCCYCTDS VGCGCCCMCTDS VGCGCCCCCTDS Direction: Backward Position #: 1 Overlap #: 12 Alignment: VGCGCCCYCTDS VGCGCCCMCTDS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rgyGCCMyCTksTGGccd Original Motif Original Motif VGCGCCCCCTDS RVYGCCCYCTKSTGGCHD VGCGCCCYCTDSTGGCHD Direction: Forward Position #: 1 Overlap #: 12 Alignment: VGCGCCCCCTDS------ RVYGCCCYCTKSTGGCHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yrcrGYGCCMyCTGGtG Original Motif Original Motif VGCGCCCYCTDSTGGCHD HVCAGCGCCCYCTGGTG VVCRSCSCCYBCTGGYGD Direction: Forward Position #: 1 Overlap #: 17 Alignment: VGCGCCCYCTDSTGGCHD HVCAGCGCCCYCTGGTG- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif myrGYGCCmCCTast Original Motif Original Motif VVCRSCSCCYBCTGGYGD VBAGCGCCMCCTAST VBRGCGCCVCCTDSTGGYGD Direction: Forward Position #: 3 Overlap #: 13 Alignment: --VVCRSCSCCYBCTGGYGD VBAGCGCCMCCTAST----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asCAGrkGGCrsy Reverse Complement Reverse Complement DCKCCASDAGGBGGCGCKBB BSKGCCCMCTGST DSKSCMSHMKGBKGCGCKBB Direction: Forward Position #: 1 Overlap #: 13 Alignment: DCKCCASDAGGBGGCGCKBB BSKGCCCMCTGST------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 138 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- grCCACyAGAkG grCCACyAGAkG Original Motif Original Motif DDCCACYAGAKG DDCCACYAGAKG DDCCACYAGAKG Direction: Forward Position #: 1 Overlap #: 12 Alignment: DDCCACYAGAKG DDCCACYAGAKG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wgGCCAshAGrGGGCrsy Original Motif Original Motif DDCCACYAGAKG HDGCCACHAGRGGGCRBY HDGCCACYAGAGGGCRBY Direction: Forward Position #: 2 Overlap #: 12 Alignment: -DDCCACYAGAKG----- HDGCCACHAGRGGGCRBY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CTCF Combined Motif Reverse Complement Original Motif KBKGCCCTCTMGTGGCHH YDRCCASYAGRKGGCRSYV KBTGCCCWCTAGKGGVCDSYV Direction: Forward Position #: 3 Overlap #: 16 Alignment: KBKGCCCTCTMGTGGCHH--- --YDRCCASYAGRKGGCRSYV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rgyGCCMyCTksTGGccd Combined Motif Reverse Complement Reverse Complement BMSDGVCCRCTAGWGGGCABY DDGCCASYAGMGGGCKVM BMSDGBCCACYAGAGGGCDVH Direction: Forward Position #: 4 Overlap #: 18 Alignment: BMSDGVCCRCTAGWGGGCABY ---DDGCCASYAGMGGGCKVM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- gwGGCCAGmAGAGGGCrby Combined Motif Original Motif Original Motif BMSDGBCCACYAGAGGGCDVH VHGGCCAGMAGAGGGCRBY BMSDGGCCASHAGAGGGCRBH Direction: Forward Position #: 3 Overlap #: 19 Alignment: BMSDGBCCACYAGAGGGCDVH --VHGGCCAGMAGAGGGCRBY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 139 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- mkCTyTTCsg vkCKCTkCGk Original Motif Original Motif HBCTTTTCBD VDCTCTKCGB VBCTYTTCGB Direction: Backward Position #: 1 Overlap #: 10 Alignment: HBCTTTTCBD VDCTCTKCGB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Original Motif Reverse Complement VBCTYTTCGB GGYGCTGTCCATGGTGCTGAA GGHDCTSTYCVDGGTGCTGAA Direction: Forward Position #: 3 Overlap #: 10 Alignment: --VBCTYTTCGB--------- GGYGCTGTCCATGGTGCTGAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif dwCAGAAGwh Reverse Complement Original Motif TTCAGCACCDVGKASAGHDCC DHCAGAAGDH DHCAGMASCHVGKASAGHDCC Direction: Forward Position #: 1 Overlap #: 10 Alignment: TTCAGCACCDVGKASAGHDCC DHCAGAAGDH----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ctCTTAACyw Original Motif Original Motif DHCAGMASCHVGKASAGHDCC HHCTTAACHD BHCWKAACHDVGKASAGHDCC Direction: Forward Position #: 1 Overlap #: 10 Alignment: DHCAGMASCHVGKASAGHDCC HHCTTAACHD----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif raCAAAACam Original Motif Original Motif BHCWKAACHDVGKASAGHDCC DACAAAACAH DHCAAAACHHVGKASAGHDCC Direction: Forward Position #: 1 Overlap #: 10 Alignment: BHCWKAACHDVGKASAGHDCC DACAAAACAH----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 140 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- vkCKCTkCGk mkCTyTTCsg Original Motif Original Motif VDCTCTKCGB HBCTTTTCBD VBCTYTTCGB Direction: Backward Position #: 1 Overlap #: 10 Alignment: VDCTCTKCGB HBCTTTTCBD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGCwGCGss Original Motif Original Motif VBCTYTTCGB VSCGCDGCGSB VBCKCTKCGBB Direction: Forward Position #: 1 Overlap #: 10 Alignment: VBCTYTTCGB- VSCGCDGCGSB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGGCrsTGCrs Reverse Complement Original Motif BBCGYAGYGBV VVGGCRSTGCVB VBSGCRSYGCVB Direction: Forward Position #: 1 Overlap #: 11 Alignment: BBCGYAGYGBV- VVGGCRSTGCVB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif csCsCCTCCcc Original Motif Reverse Complement VBSGCRSYGCVB BDGGAGGGGBV BBGGMGGBGBVB Direction: Forward Position #: 1 Overlap #: 11 Alignment: VBSGCRSYGCVB BDGGAGGGGBV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Reverse Complement Original Motif BVBCBCCRCCBB DGVBCABTGDWGCGKRRCSR BVDSBSCDCYBVWGCGKRRCSR Direction: Forward Position #: 3 Overlap #: 10 Alignment: BVBCBCCRCCBB---------- --DGVBCABTGDWGCGKRRCSR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 141 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- raCAAAACam dwCAGAAGwh Original Motif Original Motif DACAAAACAH DHCAGAAGDH DDCARAASHH Direction: Forward Position #: 1 Overlap #: 10 Alignment: DACAAAACAH DHCAGAAGDH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ctCTTAACyw Reverse Complement Reverse Complement HHSTTKTGDD DDGTTAAGHD HDGTTWWGHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: HHSTTKTGDD DDGTTAAGHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTwAAAAww Original Motif Reverse Complement HDGTTWWGHD HHTTTTWADD HDKTTTWRHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: HDGTTWWGHD HHTTTTWADD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtATTTTTAww Reverse Complement Reverse Complement DHMWAAARDH WWTAAAAATAD DHTAAAAATHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DHMWAAARDH- WWTAAAAATAD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif mkCTyTTCsg Reverse Complement Original Motif DHATTTTTAHD HBCTTTTCBD HDMTTTTYVDD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DHATTTTTAHD HBCTTTTCBD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 142 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ctCTTAACyw raCAAAACam Reverse Complement Reverse Complement DDGTTAAGHD HTGTTTTGTD HDGTTWWGHD Direction: Backward Position #: 1 Overlap #: 10 Alignment: DDGTTAAGHD HTGTTTTGTD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif mkCTyTTCsg Original Motif Reverse Complement HDGTTWWGHD HBGAAAAGBD HBGWWAAGHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: HDGTTWWGHD HBGAAAAGBD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif dwCAGAAGwh Reverse Complement Reverse Complement HHCTTWWCVD HDCTTCTGHD HHCTTHTSHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: HHCTTWWCVD HDCTTCTGHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Esrrb Reverse Complement Original Motif HHSADAAGHD VBBYCAAGGTCA HBSWVAAGGTCA Direction: Forward Position #: 1 Overlap #: 10 Alignment: HHSADAAGHD-- VBBYCAAGGTCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR2 Original Motif Reverse Complement HBSWVAAGGTCA BAGGYCABHBTGACCKHV BHGGHCAAGBTSACCKHV Direction: Forward Position #: 2 Overlap #: 12 Alignment: -HBSWVAAGGTCA----- BAGGYCABHBTGACCKHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 143 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- AgmAGAGGGCrscAGak asmAGRGGGCrCTGsmkc Original Motif Original Motif AGMAGAGGGCASCAGAK ASMAGAGGGCRCTGSABH HAGMAGAGGGCRSYRGAB Direction: Backward Position #: 2 Overlap #: 17 Alignment: AGMAGAGGGCASCAGAK- ASMAGAGGGCRCTGSABH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ctCTrsyGCCmCCTast Reverse Complement Original Motif VTCKMSKGCCCTCTYCTD HDCTGSYGCCMCCTAST VTCTVSTGCCCYCTHSTD Direction: Forward Position #: 1 Overlap #: 17 Alignment: VTCKMSKGCCCTCTYCTD HDCTGSYGCCMCCTAST- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rsyAGrkGGCGCCmyCTrsy Original Motif Original Motif VTCTVSTGCCCYCTHSTD DSYAGRKGGCGCCMYCTRSH VBCWGGKGSCVCCWHCTDSH Direction: Forward Position #: 1 Overlap #: 18 Alignment: VTCTVSTGCCCYCTHSTD-- DSYAGRKGGCGCCMYCTRSH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Reverse Complement Original Motif HSHAGDWGGVGSCRCCWGVB VDBHMAGGTCACCCTGACCY HSHDGBHVRGGBCACCHKGHCCY Direction: Forward Position #: 4 Overlap #: 17 Alignment: HSHAGDWGGVGSCRCCWGVB--- ---VDBHMAGGTCACCCTGACCY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asyAGrkGGCRGCAga Original Motif Original Motif HSHDGBHVRGGBCACCHKGHCCY ASYAGRKGGCAGCABH ASHAGRBGGCRGCAVHHKGHCCY Direction: Forward Position #: 1 Overlap #: 16 Alignment: HSHDGBHVRGGBCACCHKGHCCY ASYAGRKGGCAGCABH------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 144 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ctCTrsyGCCmCCTast AgmAGAGGGCrscAGak Reverse Complement Original Motif ASTAGGYGGCMSCAGDD AGMAGAGGGCASCAGAK ASHAGRKGGCASCAGAD Direction: Forward Position #: 1 Overlap #: 17 Alignment: ASTAGGYGGCMSCAGDD AGMAGAGGGCASCAGAK ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rsyAGrkGGCGCCmyCTrsy Original Motif Original Motif ASHAGRKGGCASCAGAD DSYAGRKGGCGCCMYCTRSH ASHAGRKGGCRCCABMTRSH Direction: Forward Position #: 1 Overlap #: 17 Alignment: ASHAGRKGGCASCAGAD--- DSYAGRKGGCGCCMYCTRSH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asmAGRGGGCrCTGsmkc Original Motif Original Motif ASHAGRKGGCRCCABMTRSH ASMAGAGGGCRCTGSABH ASHAGRGGGCRCYRSMBVSH Direction: Forward Position #: 1 Overlap #: 18 Alignment: ASHAGRKGGCRCCABMTRSH ASMAGAGGGCRCTGSABH-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Reverse Complement Original Motif HSBVYSMMGMGCCCKCTDST VDBHMAGGTCACCCTGACCY HSBVBBMMRVGYCMBCYTGHCCY Direction: Forward Position #: 4 Overlap #: 17 Alignment: HSBVYSMMGMGCCCKCTDST--- ---VDBHMAGGTCACCCTGACCY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- asyAGrkGGCRGCAga Combined Motif Original Motif Reverse Complement HSBVBBMMRVGYCMBCYTGHCCY HBTGCTGCCYMCTKST HSBVBBTVSBGCCYHCTKSHCCY Direction: Forward Position #: 5 Overlap #: 16 Alignment: HSBVBBMMRVGYCMBCYTGHCCY ----HBTGCTGCCYMCTKST--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 145 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- grCCACyAGAkG grCCACyAGAkG Original Motif Original Motif DDCCACYAGAKG DDCCACYAGAKG DDCCACYAGAKG Direction: Forward Position #: 1 Overlap #: 12 Alignment: DDCCACYAGAKG DDCCACYAGAKG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Original Motif Original Motif DDCCACYAGAKG YDRCCASYAGRKGGCRSYV YDDCCACYAGAKGGCRSYV Direction: Forward Position #: 2 Overlap #: 12 Alignment: -DDCCACYAGAKG------ YDRCCASYAGRKGGCRSYV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wgGCCAshAGrGGGCrsy Original Motif Original Motif YDDCCACYAGAKGGCRSYV HDGCCACHAGRGGGCRBY HDGCCACHAGAGGGCRSYV Direction: Forward Position #: 1 Overlap #: 18 Alignment: YDDCCACYAGAKGGCRSYV HDGCCACHAGRGGGCRBY- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rgyGCCMyCTksTGGccd Original Motif Reverse Complement HDGCCACHAGAGGGCRSYV DDGCCASYAGMGGGCKVM HDGCCASYAGAGGGCGSHV Direction: Forward Position #: 1 Overlap #: 18 Alignment: HDGCCACHAGAGGGCRSYV DDGCCASYAGMGGGCKVM- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif gwGGCCAGmAGAGGGCrby Original Motif Original Motif HDGCCASYAGAGGGCGSHV VHGGCCAGMAGAGGGCRBY VHGGCCASHAGAGGGCRBHV Direction: Forward Position #: 2 Overlap #: 18 Alignment: -HDGCCASYAGAGGGCGSHV VHGGCCAGMAGAGGGCRBY- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 146 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- myrGYGCCmCCTast yrcrGYGCCMyCTGGtG Original Motif Original Motif VBAGCGCCMCCTAST HVCAGCGCCCYCTGGTG HVCAGCGCCMYCTRGTG Direction: Forward Position #: 2 Overlap #: 15 Alignment: -VBAGCGCCMCCTAST- HVCAGCGCCCYCTGGTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ctCTrsyGCCmCCTast Original Motif Original Motif HVCAGCGCCMYCTRGTG HDCTGSYGCCMCCTAST HHCTRGYGCCMCCTRSTG Direction: Forward Position #: 2 Overlap #: 16 Alignment: -HVCAGCGCCMYCTRGTG HDCTGSYGCCMCCTAST- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rsyAGrkGGCGCCmyCTrsy Original Motif Reverse Complement HHCTRGYGCCMCCTRSTG HSKAGKYGGCGCCRMCTMSD HBBWGGYGSCVCCWMSTVSD Direction: Forward Position #: 1 Overlap #: 18 Alignment: HHCTRGYGCCMCCTRSTG-- HSKAGKYGGCGCCRMCTMSD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asmAGRGGGCrCTGsmkc Reverse Complement Original Motif DSVASYWGGVGSCMCCWBBD ASMAGAGGGCRCTGSABH ASMAGDGGGCGSYVCMDBBD Direction: Forward Position #: 1 Overlap #: 18 Alignment: DSVASYWGGVGSCMCCWBBD ASMAGAGGGCRCTGSABH-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- yvTGCyGCCmCCwGgtG Combined Motif Reverse Complement Original Motif HBBDRGVMSCGCCCDCTRST BVTGCTGCCACCWGGDG HBBDDBHVSYGCCMBCTGSDG Direction: Forward Position #: 5 Overlap #: 16 Alignment: HBBDRGVMSCGCCCDCTRST- ----BVTGCTGCCACCWGGDG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 147 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- asCAGrkGGCrsy CasCAGrGGGCrsy Original Motif Original Motif ASCAGRGGGCRSB CACCAGRGGGCRSB ASCAGRGGGCRSBC Direction: Backward Position #: 1 Overlap #: 13 Alignment: -ASCAGRGGGCRSB CACCAGRGGGCRSB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wgGCCAshAGrGGGCrsy Combined Motif Reverse Complement Reverse Complement GBSKGCCCKCTGST KBKGCCCKCTHGTGGCHH GDSKGCCCKCTBSTGGCHH Direction: Forward Position #: 2 Overlap #: 13 Alignment: GBSKGCCCKCTGST----- -KBKGCCCKCTHGTGGCHH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Reverse Complement Original Motif HDGCCASBAGRGGGCRSHC YDRCCASYAGRKGGCRSYV HDGCCASYAGRGGGCRSYM Direction: Forward Position #: 1 Overlap #: 19 Alignment: HDGCCASBAGRGGGCRSHC YDRCCASYAGRKGGCRSYV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AgmAGAGGGCrscAGak Reverse Complement Reverse Complement RMSMGCCCMCTKSTGGCHH RTCTGSTGCCCTCTYCT RTCKVSHGCCCHCTBSTGGCHH Direction: Forward Position #: 4 Overlap #: 14 Alignment: ---RMSMGCCCMCTKSTGGCHH RTCTGSTGCCCTCTYCT----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- asyAGrkGGCRGCAga Combined Motif Original Motif Reverse Complement RTCKVSHGCCCHCTBSTGGCHH HBTGCTGCCYMCTKST RTCKDBTGCYSCCTHCTGGHHH Direction: Forward Position #: 5 Overlap #: 16 Alignment: RTCKVSHGCCCHCTBSTGGCHH ----HBTGCTGCCYMCTKST-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 148 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wwTwAAAAww wtATTTTTAww Original Motif Reverse Complement DDTWAAAAHH WWTAAAAATAD DHTAAAAATHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DDTWAAAAHH- WWTAAAAATAD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- waATwAAAATAww Combined Motif Reverse Complement Reverse Complement DHATTTTTAHD DHTATTTTWATHD DHWTWTTTWWATHD Direction: Forward Position #: 2 Overlap #: 10 Alignment: DHATTTTTAHD--- -DHTATTTTWATHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 68 Combined Motif Reverse Complement Original Motif DHATWWAAAWAWHD WAAWAAAWAWWWAA DHAWAWAAAWAWWWAA Direction: Forward Position #: 3 Overlap #: 12 Alignment: DHATWWAAAWAWHD-- --WAAWAAAWAWWWAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif raCAAAACam Original Motif Original Motif DHAWAWAAAWAWWWAA DACAAAACAH DDMAAAAMAWAWWWAA Direction: Forward Position #: 1 Overlap #: 10 Alignment: DHAWAWAAAWAWWWAA DACAAAACAH------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ctCTTAACyw Original Motif Original Motif DDMAAAAMAWAWWWAA HHCTTAACHD HHCWWAACHHAWWWAA Direction: Forward Position #: 1 Overlap #: 10 Alignment: DDMAAAAMAWAWWWAA HHCTTAACHD------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 149 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- asmAGRGGGCrCTGsmkc rsyAGrkGGCGCCmyCTrsy Original Motif Original Motif ASMAGAGGGCRCTGSABH DSYAGRKGGCGCCMYCTRSH SHASHAGRKGGCGCYRYMTV Direction: Backward Position #: 3 Overlap #: 18 Alignment: ASMAGAGGGCRCTGSABH-- DSYAGRKGGCGCCMYCTRSH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Original Motif Original Motif SHASHAGRKGGCGCYRYMTV VDBHMAGGTCACCCTGACCY SHVBHMSAGGKCRCYVTSHCCY Direction: Forward Position #: 3 Overlap #: 18 Alignment: SHASHAGRKGGCGCYRYMTV-- --VDBHMAGGTCACCCTGACCY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- REST Combined Motif Original Motif Reverse Complement SHVBHMSAGGKCRCYVTSHCCY GGYGCTGTCCATGGTGCTGAA SHVBHMSAGGKSRCBCTGTCCHTGGTGCTGAA Direction: Forward Position #: 12 Overlap #: 11 Alignment: SHVBHMSAGGKCRCYVTSHCCY---------- -----------GGYGCTGTCCATGGTGCTGAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Reverse Complement Original Motif TTCAGCACCAHGGACAGBGMSYCCTSYDBBHS HWDAGHACRHHVTGTHCCHVMV TTCAGCACCAAGVACABBVHGYCCBVBVVBHS Direction: Forward Position #: 8 Overlap #: 22 Alignment: TTCAGCACCAHGGACAGBGMSYCCTSYDBBHS -------HWDAGHACRHHVTGTHCCHVMV--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- AgmAGAGGGCrscAGak Combined Motif Reverse Complement Original Motif SHVVVVVVGGMCDVBBTGTVCTTGGTGCTGAA AGMAGAGGGCASCAGAK SHAGVAGAGGVCRSBAKRTVCTTGGTGCTGAA Direction: Forward Position #: 3 Overlap #: 17 Alignment: SHVVVVVVGGMCDVBBTGTVCTTGGTGCTGAA --AGMAGAGGGCASCAGAK------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 150 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- waATwAAAATAww Motif 68 Reverse Complement Reverse Complement DHTATTTTWATHD TTWWWTWTTTWTTW TWTWTTTTTATTWT Direction: Backward Position #: 1 Overlap #: 13 Alignment: -DHTATTTTWATHD TTWWWTWTTTWTTW ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Reverse Complement Original Motif AWAATAAAAAWAWA HWDAGHACRHHVTGTHCCHVMV AHWAWRAAMAHHVWGTHCCHVMV Direction: Forward Position #: 2 Overlap #: 13 Alignment: AWAATAAAAAWAWA--------- -HWDAGHACRHHVTGTHCCHVMV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif HNF4A Reverse Complement Original Motif VRVDGGHACWBHHTRTTMWTWHT RGGBCAAAGKYCA VGVBSRAASDBYATRTTMWTWHT Direction: Forward Position #: 1 Overlap #: 13 Alignment: VRVDGGHACWBHHTRTTMWTWHT RGGBCAAAGKYCA---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NFYA Combined Motif Reverse Complement Reverse Complement AHWAWRAAMATKVDSTTMSBVCV BHVCKSATTGGMKBVV AHWDHRMWVATTGGVTBMVBVCV Direction: Forward Position #: 4 Overlap #: 16 Alignment: AHWAWRAAMATKVDSTTMSBVCV ---BHVCKSATTGGMKBVV---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NR2F1 Reverse Complement Reverse Complement VGVBVYVAVCCAATVWYMHDWHT AKGYYCAAAGRTCA ADGBBCAAAGVYMATVWYMHDWHT Direction: Forward Position #: 2 Overlap #: 13 Alignment: -VGVBVYVAVCCAATVWYMHDWHT AKGYYCAAAGRTCA---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 151 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- agrCCAGmAGrg gwGGCCAGmAGAGGGCrby Original Motif Original Motif HVGCCAGMAGRG VHGGCCAGMAGAGGGCRBY GGCRBYHGGCCAGMAGAGV Direction: Backward Position #: 7 Overlap #: 12 Alignment: -HVGCCAGMAGRG------ VHGGCCAGMAGAGGGCRBY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wgGCCAshAGrGGGCrsy Reverse Complement Reverse Complement VCTCTYCTGGCCHKBKGCC KBKGCCCKCTHGTGGCHH KCTHGTGGCHHBBYKCCYVCTCTYCTGGCC Direction: Backward Position #: 12 Overlap #: 7 Alignment: VCTCTYCTGGCCHKBKGCC----------- ------------KBKGCCCKCTHGTGGCHH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 152 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- yrCATGCAyr Ddit3Cebpa Reverse Complement Original Motif HVTGCATGKV VDRTGCAATMCC VVVTGCAWKHVC Direction: Forward Position #: 2 Overlap #: 10 Alignment: -HVTGCATGKV- VDRTGCAATMCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif TP53 Original Motif Original Motif VVVTGCAWKHVC MSGGACATGYCCGGGCATGT VVRKRCATGYCCGGGCATGT Direction: Forward Position #: 1 Overlap #: 12 Alignment: VVVTGCAWKHVC-------- MSGGACATGYCCGGGCATGT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGwGCGss Original Motif Original Motif VVRKRCATGYCCGGGCATGT BSCGWGCGBV BVCGWGCRHGYCCGGGCATGT Direction: Forward Position #: 2 Overlap #: 9 Alignment: -VVRKRCATGYCCGGGCATGT BSCGWGCGBV----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif znf143 Original Motif Reverse Complement BVCGWGCRHGYCCGGGCATGT GCMWRGCATYRTGGGAMHTB VVMRDGCATBVYSGGRCATGT Direction: Forward Position #: 1 Overlap #: 20 Alignment: BVCGWGCRHGYCCGGGCATGT GCMWRGCATYRTGGGAMHTB- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif kkAAGAGCAsy Original Motif Original Motif VVMRDGCATBVYSGGRCATGT DBAAGAGCAVH DVAAGAGCABBVYSGGRCATGT Direction: Forward Position #: 2 Overlap #: 10 Alignment: -VVMRDGCATBVYSGGRCATGT DBAAGAGCAVH----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 153 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- scAGrkGGCGcy rgCGCCmyCTgs Original Motif Reverse Complement SHAGRGGGCGCB SHAGKGGGCGCB SHAGGGGGCGCB Direction: Backward Position #: 1 Overlap #: 12 Alignment: SHAGRGGGCGCB SHAGKGGGCGCB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asCAGrkGGCrsy Reverse Complement Reverse Complement VGCGCCCCCTDS BSKGCCCMCTGST DSYGCCCMCTGST Direction: Forward Position #: 1 Overlap #: 12 Alignment: VGCGCCCCCTDS- BSKGCCCMCTGST ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Original Motif Reverse Complement DSYGCCCMCTGST BMSMGCCYMCTKSTGGMHM BVSCGCCYMCTGSTGGMHM Direction: Forward Position #: 2 Overlap #: 13 Alignment: -DSYGCCCMCTGST----- BMSMGCCYMCTKSTGGMHM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wgGCCAshAGrGGGCrsy Reverse Complement Original Motif YDRCCASCAGRKGGCGSBV HDGCCACHAGRGGGCRBY HDGCCASHAGRGGGCRSHV Direction: Forward Position #: 1 Overlap #: 18 Alignment: YDRCCASCAGRKGGCGSBV HDGCCACHAGRGGGCRBY- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CasCAGrGGGCrsy Original Motif Reverse Complement HDGCCASHAGRGGGCRSHV BSKGCCCKCTGGTG BBKGCCMBCWGRKGGCRSHV Direction: Forward Position #: 2 Overlap #: 13 Alignment: -HDGCCASHAGRGGGCRSHV BSKGCCCKCTGGTG------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 154 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- csCsCCTCCcc csCSCCdCCCcs Original Motif Original Motif VBCCCCTCCHB VBCCCCDCCCHV VBCCCCTCCCBV Direction: Forward Position #: 1 Overlap #: 11 Alignment: VBCCCCTCCHB- VBCCCCDCCCHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif scAGrkGGCGcy Reverse Complement Original Motif VBGGGAGGGGBV SHAGRGGGCGCB SBRGGDGGSGBB Direction: Forward Position #: 1 Overlap #: 12 Alignment: VBGGGAGGGGBV SHAGRGGGCGCB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rgCGCCmyCTgs Original Motif Reverse Complement SBRGGDGGSGBB SHAGKGGGCGCB SBAGGRGGCGCB Direction: Forward Position #: 1 Overlap #: 12 Alignment: SBRGGDGGSGBB SHAGKGGGCGCB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccAsCCCCAcc Reverse Complement Original Motif VGCGCCMCCTBS HVASCCCCABH VVMGCCCCMBBS Direction: Forward Position #: 1 Overlap #: 11 Alignment: VGCGCCMCCTBS HVASCCCCABH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AgmAGAGGGCrscAGak Reverse Complement Original Motif SBVYGGGGCRVV AGMAGAGGGCASCAGAK VVMHGRGGSSVBCAGAK Direction: Forward Position #: 1 Overlap #: 12 Alignment: SBVYGGGGCRVV----- AGMAGAGGGCASCAGAK ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 155 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- csCSCCdCCCcs rgCGCCmyCTgs Reverse Complement Reverse Complement VDGGGDGGGGBV SHAGKGGGCGCB SVRGGRGGSGBB Direction: Backward Position #: 1 Overlap #: 12 Alignment: VDGGGDGGGGBV SHAGKGGGCGCB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif scAGrkGGCGcy Original Motif Original Motif SVRGGRGGSGBB SHAGRGGGCGCB SBAGGGGGCGCB Direction: Forward Position #: 1 Overlap #: 12 Alignment: SVRGGRGGSGBB SHAGRGGGCGCB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Reverse Complement Reverse Complement VGCGCCCCCTBS BMSMGCCYMCTKSTGGMHM BVSCGCCYCCTDSTGGMHM Direction: Forward Position #: 2 Overlap #: 12 Alignment: -VGCGCCCCCTBS------ BMSMGCCYMCTKSTGGMHM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yrcrGYGCCMyCTGGtG Original Motif Original Motif BVSCGCCYCCTDSTGGMHM HVCAGCGCCCYCTGGTG HVBAGCGCCCYCTGSTGGMHM Direction: Forward Position #: 3 Overlap #: 15 Alignment: --BVSCGCCYCCTDSTGGMHM HVCAGCGCCCYCTGGTG---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asCAGrkGGCrsy Reverse Complement Reverse Complement YDRCCASCAGKGGGCGCTBBD BSKGCCCMCTGST BBKGCCMCCWGBKGGCGCTBBD Direction: Forward Position #: 2 Overlap #: 12 Alignment: -YDRCCASCAGKGGGCGCTBBD BSKGCCCMCTGST--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 156 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rgyGCCMyCTksTGGccd wgGCCAshAGrGGGCrsy Reverse Complement Original Motif DDGCCASYAGMGGGCKVM HDGCCACHAGRGGGCRBY DDGCCASHAGAGGGCRVH Direction: Forward Position #: 1 Overlap #: 18 Alignment: DDGCCASYAGMGGGCKVM HDGCCACHAGRGGGCRBY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif gwGGCCAGmAGAGGGCrby Reverse Complement Reverse Complement DVMGCCCTCTDSTGGCHD KBKGCCCTCTYCTGGCCHV DBBGCCCTCTDSTGGCCHV Direction: Forward Position #: 1 Overlap #: 18 Alignment: DVMGCCCTCTDSTGGCHD- KBKGCCCTCTYCTGGCCHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Original Motif Reverse Complement DBBGCCCTCTDSTGGCCHV BMSMGCCYMCTKSTGGMHM BVSHGCCCHCTDSTGGCCHV Direction: Forward Position #: 2 Overlap #: 18 Alignment: -DBBGCCCTCTDSTGGCCHV BMSMGCCYMCTKSTGGMHM- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Original Motif Original Motif BVSHGCCCHCTDSTGGCCHV TTCAGCACCATGGACAGCKCC TTCAGCACCATGGASAGCCCCCTDSTGGCCHV Direction: Forward Position #: 13 Overlap #: 9 Alignment: ------------BVSHGCCCHCTDSTGGCCHV TTCAGCACCATGGACAGCKCC----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Pax5 Reverse Complement Original Motif VHGGCCASDAGGGGGCTSTCCATGGTGCTGAA DGVBCABTGDWGCGKRRCSR DGHBVMCWSDAGBGKGVYSDCCATGGTGCTGAA Direction: Forward Position #: 2 Overlap #: 19 Alignment: -VHGGCCASDAGGGGGCTSTCCATGGTGCTGAA DGVBCABTGDWGCGKRRCSR------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 157 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wtATTTTTAww waATwAAAATAww Original Motif Reverse Complement DTATTTTTAWW DHTATTTTWATHD DDTATTTTTATDD Direction: Forward Position #: 2 Overlap #: 11 Alignment: -DTATTTTTAWW- DHTATTTTWATHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 68 Reverse Complement Original Motif DDATAAAAATADD WAAWAAAWAWWWAA WAATAAAAAWAWAA Direction: Forward Position #: 1 Overlap #: 13 Alignment: DDATAAAAATADD- WAAWAAAWAWWWAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif HNF4A Reverse Complement Reverse Complement TTWTWTTTTTATTW TGMYCTTTGBCCK TKHYMTTTKTHYTW Direction: Forward Position #: 1 Overlap #: 13 Alignment: TTWTWTTTTTATTW TGMYCTTTGBCCK- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NR2F1 Original Motif Original Motif TKHYMTTTKTHYTW TGAMCTTTGMMCYT TGAHCTTTGHMCHT Direction: Forward Position #: 1 Overlap #: 14 Alignment: TKHYMTTTKTHYTW TGAMCTTTGMMCYT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NFYA Reverse Complement Original Motif AHGYHCAAAGDTCA VBBRRCCAATSRGVDB VHBHDCMAAKVDSADB Direction: Forward Position #: 1 Overlap #: 14 Alignment: AHGYHCAAAGDTCA-- VBBRRCCAATSRGVDB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 158 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- grCCACwAGrk grCCACyAGAkG Original Motif Original Motif DDCCACWAGRK DDCCACYAGAKG DDCCACWAGAKG Direction: Forward Position #: 1 Overlap #: 11 Alignment: DDCCACWAGRK- DDCCACYAGAKG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif grCCACyAGAkG Original Motif Original Motif DDCCACWAGAKG DDCCACYAGAKG DDCCACYAGAKG Direction: Forward Position #: 1 Overlap #: 12 Alignment: DDCCACWAGAKG DDCCACYAGAKG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Original Motif Original Motif DDCCACYAGAKG YDRCCASYAGRKGGCRSYV YDDCCACYAGRKGGCRSYV Direction: Forward Position #: 2 Overlap #: 12 Alignment: -DDCCACYAGAKG------ YDRCCASYAGRKGGCRSYV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wgGCCAshAGrGGGCrsy Original Motif Original Motif YDDCCACYAGRKGGCRSYV HDGCCACHAGRGGGCRBY HDGCCACHAGRGGGCRSYV Direction: Forward Position #: 1 Overlap #: 18 Alignment: YDDCCACYAGRKGGCRSYV HDGCCACHAGRGGGCRBY- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif agrCCAGmAGrg Original Motif Original Motif HDGCCACHAGRGGGCRSYV HVGCCAGMAGRG HDGCCASMAGRGGGCRSYV Direction: Forward Position #: 1 Overlap #: 12 Alignment: HDGCCACHAGRGGGCRSYV HVGCCAGMAGRG------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 159 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- kkAAGAGCAsy brCAGGGCCrs Reverse Complement Reverse Complement HVTGCTCTTBH BBGGCCCTGBB VBKGCYCTKBB Direction: Backward Position #: 1 Overlap #: 11 Alignment: HVTGCTCTTBH BBGGCCCTGBB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif shAGrGGGCAgy Original Motif Reverse Complement VBKGCYCTKBB DBTGCCCKCTDS DBTGCCCTBTDS Direction: Forward Position #: 1 Overlap #: 11 Alignment: VBKGCYCTKBB- DBTGCCCKCTDS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Reverse Complement Reverse Complement SDABAGGGCABH VRVDGGHACAVDDKGTHCTDWH SDVDAGGGCACHVDDKGTHCTDWH Direction: Forward Position #: 3 Overlap #: 10 Alignment: SDABAGGGCABH------------ --VRVDGGHACAVDDKGTHCTDWH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Ddit3Cebpa Reverse Complement Original Motif HWDAGHACRHHVHGTGCCCTHBDS VDRTGCAATMCC HDDWGMAMWHCSHGTGCCCTHBDS Direction: Forward Position #: 1 Overlap #: 12 Alignment: HWDAGHACRHHVHGTGCCCTHBDS VDRTGCAATMCC------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yrcrGYGCCMyCTGGtG Original Motif Original Motif HDDWGMAMWHCSHGTGCCCTHBDS HVCAGCGCCCYCTGGTG HDVWGCRCCCYCTGKBSCCTHBDS Direction: Forward Position #: 1 Overlap #: 17 Alignment: HDDWGMAMWHCSHGTGCCCTHBDS HVCAGCGCCCYCTGGTG------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 160 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- brCAGGGCCrs yrcrGYGCCMyCTGGtG Original Motif Original Motif BVCAGGGCCVB HVCAGCGCCCYCTGGTG BVCAGSGCCMYCTGGTG Direction: Forward Position #: 1 Overlap #: 11 Alignment: BVCAGGGCCVB------ HVCAGCGCCCYCTGGTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGGCrsTGCrs Original Motif Reverse Complement BVCAGSGCCMYCTGGTG BVGCASMGCCVV BHGCAGVGCCVBCTGGTG Direction: Forward Position #: 2 Overlap #: 11 Alignment: -BVCAGSGCCMYCTGGTG BVGCASMGCCVV------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- kkAAGAGCAsy Combined Motif Original Motif Original Motif BHGCAGVGCCVBCTGGTG DBAAGAGCAVH BBDMAGAGCMVBCTGGTG Direction: Forward Position #: 2 Overlap #: 11 Alignment: BHGCAGVGCCVBCTGGTG -DBAAGAGCAVH------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asmAGRGGGCrCTGsmkc Original Motif Reverse Complement BBDMAGAGCMVBCTGGTG DBTSCAGMGCCCTCTRST DBBGCAGMGCCCTCTGSTG Direction: Forward Position #: 2 Overlap #: 17 Alignment: -BBDMAGAGCMVBCTGGTG DBTSCAGMGCCCTCTRST- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- REST Combined Motif Original Motif Original Motif DBBGCAGMGCCCTCTGSTG TTCAGCACCATGGACAGCKCC DBBBCAGMRCCHTSKRSWGCKCC Direction: Forward Position #: 3 Overlap #: 17 Alignment: DBBGCAGMGCCCTCTGSTG---- --TTCAGCACCATGGACAGCKCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 161 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCwGCGss ssGGCrsTGCrs Reverse Complement Original Motif BSCGCDGCGSV VVGGCRSTGCVB BVVSGCDSYGCV Direction: Backward Position #: 2 Overlap #: 11 Alignment: BSCGCDGCGSV- VVGGCRSTGCVB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yvTGCyGCCmCCwGgtG Reverse Complement Original Motif VGCKSHGCSVVB BVTGCTGCCACCWGGDG BVYGCYGCCMCCWGGDG Direction: Forward Position #: 1 Overlap #: 12 Alignment: VGCKSHGCSVVB----- BVTGCTGCCACCWGGDG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- asmAGRGGGCrCTGsmkc Combined Motif Reverse Complement Original Motif CDCCWGGYGGCMGCKVB ASMAGAGGGCRCTGSABH CDMCWRGDGGSCGCTSBABH Direction: Forward Position #: 3 Overlap #: 15 Alignment: CDCCWGGYGGCMGCKVB--- --ASMAGAGGGCRCTGSABH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- csCsCCTCCcc Combined Motif Original Motif Reverse Complement CDMCWRGDGGSCGCTSBABH BDGGAGGGGBV CVVGGAGGGGSVGCTSBABH Direction: Forward Position #: 2 Overlap #: 11 Alignment: CDMCWRGDGGSCGCTSBABH -BDGGAGGGGBV-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- csCSCCdCCCcs Combined Motif Original Motif Reverse Complement CVVGGAGGGGSVGCTSBABH VDGGGDGGGGBV CVVGVDGGGGGGGSBVBABH Direction: Forward Position #: 5 Overlap #: 12 Alignment: CVVGGAGGGGSVGCTSBABH ----VDGGGDGGGGBV---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 162 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ccAsCCCCAcc csCsCCTCCcc Reverse Complement Reverse Complement DBTGGGGSTVD BDGGAGGGGBV BBKGRGGSKBV Direction: Forward Position #: 1 Overlap #: 11 Alignment: DBTGGGGSTVD BDGGAGGGGBV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif myrGYGCCmCCTast Reverse Complement Original Motif VBYSCCMCYBB VBAGCGCCMCCTAST VBHGCSCCHCCTAST Direction: Forward Position #: 1 Overlap #: 11 Alignment: VBYSCCMCYBB---- VBAGCGCCMCCTAST ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- znf143 Combined Motif Original Motif Original Motif VBHGCSCCHCCTAST BAHYTCCCAKMATGCMWYGC VBBVCBYCCCMTVVTGCMWYGC Direction: Forward Position #: 3 Overlap #: 13 Alignment: VBHGCSCCHCCTAST------- --BAHYTCCCAKMATGCMWYGC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif csCSCCdCCCcs Original Motif Original Motif VBBVCBYCCCMTVVTGCMWYGC VBCCCCDCCCHV VBCSCCHCCCMBVVTGCMWYGC Direction: Forward Position #: 1 Overlap #: 12 Alignment: VBBVCBYCCCMTVVTGCMWYGC VBCCCCDCCCHV---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARG Combined Motif Original Motif Original Motif VBCSCCHCCCMBVVTGCMWYGC STAGGTCACBGTGACCYABT VBCSCCHCCCVTAGKKCAHHGHGACCYABT Direction: Forward Position #: 11 Overlap #: 12 Alignment: VBCSCCHCCCMBVVTGCMWYGC-------- ----------STAGGTCACBGTGACCYABT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 163 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- gwGGCCAGmAGAGGGCrby TP53 Reverse Complement Reverse Complement KBKGCCCTCTYCTGGCCHV ACATGCCCGGKCATGTCCSR BDTGCCCKSTCMTGKCCVVA Direction: Backward Position #: 1 Overlap #: 19 Alignment: -KBKGCCCTCTYCTGGCCHV ACATGCCCGGKCATGTCCSR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Original Motif Reverse Complement BDTGCCCKSTCMTGKCCVVA GGYGCTGTCCATGGTGCTGAA GGYGCTGTCCATGGTSCTGMMCKSTCMTGKCCVVA Direction: Forward Position #: 16 Overlap #: 6 Alignment: ---------------BDTGCCCKSTCMTGKCCVVA GGYGCTGTCCATGGTGCTGAA-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wgGCCAshAGrGGGCrsy Combined Motif Original Motif Reverse Complement GGYGCTGTCCATGGTSCTGMMCKSTCMTGKCCVVA KBKGCCCKCTHGTGGCHH GGYGCTGTSCCYKSTBSTGSCCDSTCMTGKCCVVA Direction: Forward Position #: 6 Overlap #: 18 Alignment: GGYGCTGTCCATGGTSCTGMMCKSTCMTGKCCVVA -----KBKGCCCKCTHGTGGCHH------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rgyGCCMyCTksTGGccd Reverse Complement Original Motif TVVGGYCAYGASDGGSCASBASYKGGSACAGCKCC RVYGCCCYCTKSTGGCHD DVBGSCCWCKRSTGGCCASBASYKGGSACAGCKCC Direction: Forward Position #: 1 Overlap #: 18 Alignment: TVVGGYCAYGASDGGSCASBASYKGGSACAGCKCC RVYGCCCYCTKSTGGCHD----------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Original Motif Reverse Complement DVBGSCCWCKRSTGGCCASBASYKGGSACAGCKCC BMSMGCCYMCTKSTGGMHM BHSMGCCCMCTDSTGGCCASBASYKGGSACAGCKCC Direction: Forward Position #: 2 Overlap #: 18 Alignment: -DVBGSCCWCKRSTGGCCASBASYKGGSACAGCKCC BMSMGCCYMCTKSTGGMHM----------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 164 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- asyAGrkGGCRGCAga ctCTrsyGCCmCCTast Reverse Complement Original Motif HBTGCTGCCYMCTKST HDCTGSYGCCMCCTAST THBYKSBKSCCMCYTVB Direction: Backward Position #: 2 Overlap #: 16 Alignment: HBTGCTGCCYMCTKST- HDCTGSYGCCMCCTAST ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- yvTGCyGCCmCCwGgtG Combined Motif Original Motif Original Motif THBYKSBKSCCMCYTVB BVTGCTGCCACCWGGDG THBHTGCBGCCMCYTGDDG Direction: Forward Position #: 3 Overlap #: 15 Alignment: THBYKSBKSCCMCYTVB-- --BVTGCTGCCACCWGGDG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AgmAGAGGGCrscAGak Original Motif Reverse Complement THBHTGCBGCCMCYTGDDG RTCTGSTGCCCTCTYCT DHCTKSBGSCCHCTTSDDG Direction: Forward Position #: 1 Overlap #: 17 Alignment: THBHTGCBGCCMCYTGDDG RTCTGSTGCCCTCTYCT-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rsyAGrkGGCGCCmyCTrsy Original Motif Original Motif DHCTKSBGSCCHCTTSDDG DSYAGRKGGCGCCMYCTRSH DBYWGGKGGCSCCHYCTDGH Direction: Forward Position #: 1 Overlap #: 19 Alignment: DHCTKSBGSCCHCTTSDDG- DSYAGRKGGCGCCMYCTRSH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- asmAGRGGGCrCTGsmkc Combined Motif Reverse Complement Original Motif HCHAGMDGGSGCCRCCWKBD ASMAGAGGGCRCTGSABH HCHAGMAGRGGSCRCYDBVDH Direction: Forward Position #: 4 Overlap #: 17 Alignment: HCHAGMDGGSGCCRCCWKBD- ---ASMAGAGGGCRCTGSABH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 165 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wgGCCAshAGrGGGCrsy gwGGCCAGmAGAGGGCrby Original Motif Original Motif HDGCCACHAGRGGGCRBY VHGGCCAGMAGAGGGCRBY HGGCCASHAGAGGGCRBYV Direction: Backward Position #: 1 Overlap #: 18 Alignment: -HDGCCACHAGRGGGCRBY VHGGCCAGMAGAGGGCRBY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Original Motif Original Motif HGGCCASHAGAGGGCRBYV YDRCCASYAGRKGGCRSYV HGGCCASHAGRGGGCRSYV Direction: Forward Position #: 1 Overlap #: 19 Alignment: HGGCCASHAGAGGGCRBYV YDRCCASYAGRKGGCRSYV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rgyGCCMyCTksTGGccd Original Motif Reverse Complement HGGCCASHAGRGGGCRSYV DDGCCASYAGMGGGCKVM HDGCCASYAGAGGGCGSHV Direction: Forward Position #: 1 Overlap #: 18 Alignment: HGGCCASHAGRGGGCRSYV DDGCCASYAGMGGGCKVM- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Pax5 Original Motif Original Motif HDGCCASYAGAGGGCGSHV DGVBCABTGDWGCGKRRCSR DGDCCASYRGAGSGYRVCVR Direction: Forward Position #: 1 Overlap #: 19 Alignment: HDGCCASYAGAGGGCGSHV- DGVBCABTGDWGCGKRRCSR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TP53 Combined Motif Reverse Complement Reverse Complement MVGVMKCSCTCKMSTGGHCD ACATGCCCGGKCATGTCCSR MMSAHGCCCKSKCATGKCCVR Direction: Forward Position #: 2 Overlap #: 19 Alignment: MVGVMKCSCTCKMSTGGHCD- -ACATGCCCGGKCATGTCCSR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 166 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CasCAGrGGGCrsy wgGCCAshAGrGGGCrsy Original Motif Original Motif CACCAGRGGGCRSB HDGCCACHAGRGGGCRBY HDGCCACCAGRGGGCRSH Direction: Forward Position #: 5 Overlap #: 14 Alignment: ----CACCAGRGGGCRSB HDGCCACHAGRGGGCRBY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif gwGGCCAGmAGAGGGCrby Reverse Complement Reverse Complement DSKGCCCKCTGGTGGCHH KBKGCCCTCTYCTGGCCHV KBKGCCCTCTBSTGGCCHV Direction: Forward Position #: 1 Overlap #: 18 Alignment: DSKGCCCKCTGGTGGCHH- KBKGCCCTCTYCTGGCCHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CTCF Original Motif Reverse Complement KBKGCCCTCTBSTGGCCHV BMSMGCCYMCTKSTGGMHM BVSBGCCCHCTDSTGGCCHV Direction: Forward Position #: 2 Overlap #: 18 Alignment: -KBKGCCCTCTBSTGGCCHV BMSMGCCYMCTKSTGGMHM- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yrcrGYGCCMyCTGGtG Original Motif Original Motif BVSBGCCCHCTDSTGGCCHV HVCAGCGCCCYCTGGTG HVBVGYGCCCYCTGSTGGCCHV Direction: Forward Position #: 3 Overlap #: 15 Alignment: --BVSBGCCCHCTDSTGGCCHV HVCAGCGCCCYCTGGTG----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rgyGCCMyCTksTGGccd Reverse Complement Original Motif VHGGCCASCAGMGGGCKCBBBD RVYGCCCYCTKSTGGCHD VBBGCCMYCWGVKGGCBBBBBD Direction: Forward Position #: 1 Overlap #: 18 Alignment: VHGGCCASCAGMGGGCKCBBBD RVYGCCCYCTKSTGGCHD---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 167 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rsyAGrkGGCGCCmyCTrsy ESR1 Original Motif Original Motif DSYAGRKGGCGCCMYCTRSH VDBHMAGGTCACCCTGACCY VBBHSRKGKCRCCMTSWVCY Direction: Forward Position #: 1 Overlap #: 20 Alignment: DSYAGRKGGCGCCMYCTRSH VDBHMAGGTCACCCTGACCY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Reverse Complement Reverse Complement MGVWSARGGKGYCYKSHBBB MSGKKRCGCWDCABTGBBCD MSGDBAVGSKKCMBTVHBCD Direction: Forward Position #: 1 Overlap #: 20 Alignment: MGVWSARGGKGYCYKSHBBB MSGKKRCGCWDCABTGBBCD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Ar Reverse Complement Original Motif DGBHVABRGYRSCVTBDCSY HWDAGHACRHHVTGTHCCHVMV HDHAGAVCRYHSYGTHCCVBMV Direction: Forward Position #: 1 Overlap #: 20 Alignment: DGBHVABRGYRSCVTBDCSY-- HWDAGHACRHHVTGTHCCHVMV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PPARG Original Motif Reverse Complement HDHAGAVCRYHSYGTHCCVBMV ABTMGGTCACBGTGACCTAS ADTMGRHCACVSTGWCCBABMV Direction: Forward Position #: 1 Overlap #: 20 Alignment: HDHAGAVCRYHSYGTHCCVBMV ABTMGGTCACBGTGACCTAS-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asmAGRGGGCrCTGsmkc Original Motif Original Motif ADTMGRHCACVSTGWCCBABMV ASMAGAGGGCRCTGSABH AVHAGRKSGCVSTGHMBBABMV Direction: Forward Position #: 1 Overlap #: 18 Alignment: ADTMGRHCACVSTGWCCBABMV ASMAGAGGGCRCTGSABH---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 168 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- yrcrGYGCCMyCTGGtG yvTGCyGCCmCCwGgtG Original Motif Original Motif HVCAGCGCCCYCTGGTG BVTGCTGCCACCWGGDG HVYRSYGCCMCCTGGTG Direction: Forward Position #: 1 Overlap #: 17 Alignment: HVCAGCGCCCYCTGGTG BVTGCTGCCACCWGGDG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif asmAGRGGGCrCTGsmkc Original Motif Reverse Complement HVYRSYGCCMCCTGGTG DBTSCAGMGCCCTCTRST BBYGCHGCSCCCTSKDST Direction: Forward Position #: 1 Overlap #: 17 Alignment: HVYRSYGCCMCCTGGTG- DBTSCAGMGCCCTCTRST ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Reverse Complement Original Motif ASDRSAGGGSGCHGCMBB VDBHMAGGTCACCCTGACCY ASDDSHVRGGKCASCMTGACCY Direction: Forward Position #: 3 Overlap #: 16 Alignment: ASDRSAGGGSGCHGCMBB---- --VDBHMAGGTCACCCTGACCY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Original Motif Original Motif ASDDSHVRGGKCASCMTGACCY HWDAGHACRHHVTGTHCCHVMV ASDDVHDRGVDCABCVTGWCCYHVMV Direction: Forward Position #: 5 Overlap #: 18 Alignment: ASDDSHVRGGKCASCMTGACCY---- ----HWDAGHACRHHVTGTHCCHVMV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rgyGCCMyCTksTGGccd Original Motif Reverse Complement ASDDVHDRGVDCABCVTGWCCYHVMV DDGCCASYAGMGGGCKVM DDGMCAVHAGAGGGCDVHVTGWCCYHVMV Direction: Forward Position #: 4 Overlap #: 15 Alignment: ---ASDDVHDRGVDCABCVTGWCCYHVMV DDGCCASYAGMGGGCKVM----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 169 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- yvTGCyGCCmCCwGgtG yrcrGYGCCMyCTGGtG Original Motif Original Motif BVTGCTGCCACCWGGDG HVCAGCGCCCYCTGGTG HVYRSYGCCMCCTGGTG Direction: Forward Position #: 1 Overlap #: 17 Alignment: BVTGCTGCCACCWGGDG HVCAGCGCCCYCTGGTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CTCF Combined Motif Original Motif Reverse Complement HVYRSYGCCMCCTGGTG BMSMGCCYMCTKSTGGMHM HVBVSCGCCCCCTGGTGGMHM Direction: Forward Position #: 3 Overlap #: 15 Alignment: HVYRSYGCCMCCTGGTG---- --BMSMGCCYMCTKSTGGMHM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rsyAGrkGGCGCCmyCTrsy Original Motif Original Motif HVBVSCGCCCCCTGGTGGMHM DSYAGRKGGCGCCMYCTRSH DBHHGGBGSCVCCWBSTGGHHM Direction: Forward Position #: 2 Overlap #: 19 Alignment: -HVBVSCGCCCCCTGGTGGMHM DSYAGRKGGCGCCMYCTRSH-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rgyGCCMyCTksTGGccd Combined Motif Original Motif Original Motif DBHHGGBGSCVCCWBSTGGHHM RVYGCCCYCTKSTGGCHD DBHHRGYGCCVYCTBSTGGCHH Direction: Forward Position #: 5 Overlap #: 18 Alignment: DBHHGGBGSCVCCWBSTGGHHM ----RVYGCCCYCTKSTGGCHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif gwGGCCAGmAGAGGGCrby Reverse Complement Original Motif HDGCCASBAGKVGGCKCMHDBD VHGGCCAGMAGAGGGCRBY VHGGCCAGHAGRGGGCDBHHDBD Direction: Forward Position #: 2 Overlap #: 18 Alignment: -HDGCCASBAGKVGGCKCMHDBD VHGGCCAGMAGAGGGCRBY---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 170 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssGGCrsTGCrs asmAGRGGGCrCTGsmkc Original Motif Original Motif VVGGCRSTGCVB ASMAGAGGGCRCTGSABH HRGGGCRCTGCVBASMAG Direction: Backward Position #: 2 Overlap #: 12 Alignment: -----VVGGCRSTGCVB- ASMAGAGGGCRCTGSABH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Zfx Original Motif Reverse Complement HRGGGCRCTGCVBASMAG VAGGCCBBGGCVBB VAGGSCDSKGCVBVSMAG Direction: Forward Position #: 1 Overlap #: 14 Alignment: HRGGGCRCTGCVBASMAG VAGGCCBBGGCVBB---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- csCSCCdCCCcs Combined Motif Reverse Complement Reverse Complement CTRSBBVGCRSHGSCCTV VDGGGDGGGGBV CTRSBGGGVGGSGSCCTV Direction: Forward Position #: 4 Overlap #: 12 Alignment: CTRSBBVGCRSHGSCCTV ---VDGGGDGGGGBV--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ctCTrsyGCCmCCTast Reverse Complement Original Motif VAGGSCSCCVCCCBSMAG HDCTGSYGCCMCCTAST HBMKGSCGCCVCCYVSHAG Direction: Forward Position #: 2 Overlap #: 16 Alignment: -VAGGSCSCCVCCCBSMAG HDCTGSYGCCMCCTAST-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif myrGYGCCmCCTast Original Motif Reverse Complement HBMKGSCGCCVCCYVSHAG ASTAGGYGGCGCTBB HBHDGGYGSCDCYBHSHAG Direction: Forward Position #: 1 Overlap #: 15 Alignment: HBMKGSCGCCVCCYVSHAG ASTAGGYGGCGCTBB---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 171 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ysGTGGCCACsr yvTGCyGCCmCCwGgtG Reverse Complement Original Motif VBGTGGCCACVB BVTGCTGCCACCWGGDG GCBGYSRCCASVBBVTG Direction: Backward Position #: 2 Overlap #: 12 Alignment: ----VBGTGGCCACVB- BVTGCTGCCACCWGGDG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Original Motif Original Motif GCBGYSRCCASVBBVTG VDBHMAGGTCACCCTGACCY VGVHGHGGYCASVBTGWSCY Direction: Forward Position #: 2 Overlap #: 17 Alignment: -GCBGYSRCCASVBBVTG-- VDBHMAGGTCACCCTGACCY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PPARG Reverse Complement Original Motif MGSWCABVSTGKCCHCDVCV STAGGTCACBGTGACCYABT STAGGTCABBGTGDCCHMBDCV Direction: Forward Position #: 3 Overlap #: 18 Alignment: --MGSWCABVSTGKCCHCDVCV STAGGTCACBGTGACCYABT-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif myrGYGCCmCCTast Original Motif Reverse Complement STAGGTCABBGTGDCCHMBDCV ASTAGGYGGCGCTBB ASTAGGTSRCGSTGDCCHMBDCV Direction: Forward Position #: 2 Overlap #: 14 Alignment: -STAGGTCABBGTGDCCHMBDCV ASTAGGYGGCGCTBB-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGGCrsTGCrs Reverse Complement Reverse Complement VGDBYHGGDCASCGMSACCTAST BVGCASMGCCVV BVGCVBMGSCBVSCGMSACCTAST Direction: Forward Position #: 2 Overlap #: 11 Alignment: -VGDBYHGGDCASCGMSACCTAST BVGCASMGCCVV------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Results created by MOTIFSIM on 11-19-2016 22:45:25 Runtime: 1028.98 seconds MOTIFSIM is written by Ngoc Tam L. 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