MOTIFSIM - MOTIF SIMilarity Detection Tool

Version 2.1

INPUT

Input Parameters
Number of files: 2
Number of top significant motifs: 10
Number of best matches: 10
Similarity cutoff >= 0.75
Matching motif database: UniProbe Mus Musculus
Phylogenetic tree: Yes
Combined similar motifs: Yes
Output file type: All
Output file format: All

Input files and motif counts
File name Count of motifs Dataset number
MEME-ChIP_DM721.txt 11 1
PScanChIP_DM721.txt 37 2

RESULTS

Top 10 Significant Motifs - Global Matching (Highest to Lowest)

Dataset #: 1 Motif ID: 4 Motif name: Motif 4

Original motif     Consensus sequence: CTCTGY Reverse complement motif     Consensus sequence: KCAGAG

Best Matches for Top Significant Motif ID 4 (Highest to Lowest)

Dataset #: 2
Motif ID: 43
Motif name: NR1H2RXRA
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Backward
Position number: 7
Number of overlap: 6
Similarity score: 0.012269

Alignment:
AAAGGTCAAAGGTCAAC
-----KCAGAG------

Original motif     Consensus sequence: AAAGGTCAAAGGTCAAC Reverse complement motif     Consensus sequence: GTTGACCTTTGACCTTT


Dataset #: 2
Motif ID: 20
Motif name: PPARGRXRA
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Forward
Position number: 6
Number of overlap: 6
Similarity score: 0.0140102

Alignment:
BTRGGDCARAGGKCA
-----KCAGAG----

Original motif     Consensus sequence: BTRGGDCARAGGKCA Reverse complement motif     Consensus sequence: TGRCCTKTGHCCKAB


Dataset #: 2
Motif ID: 22
Motif name: NR2F1
Matching format of first motif: Reverse Complement
Matching format of second motif: Reverse Complement
Direction: Backward
Position number: 5
Number of overlap: 6
Similarity score: 0.0186793

Alignment:
AKGYYCAAAGRTCA
----KCAGAG----

Original motif     Consensus sequence: TGAMCTTTGMMCYT Reverse complement motif     Consensus sequence: AKGYYCAAAGRTCA


Dataset #: 2
Motif ID: 34
Motif name: HNF4A
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Forward
Position number: 4
Number of overlap: 6
Similarity score: 0.020602

Alignment:
RGGBCAAAGKYCA
---KCAGAG----

Original motif     Consensus sequence: RGGBCAAAGKYCA Reverse complement motif     Consensus sequence: TGMYCTTTGBCCK


Dataset #: 2
Motif ID: 37
Motif name: MIZF
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Forward
Position number: 5
Number of overlap: 6
Similarity score: 0.0221665

Alignment:
BAACGTCCGC
----CTCTGY

Original motif     Consensus sequence: BAACGTCCGC Reverse complement motif     Consensus sequence: GCGGACGTTV


Dataset #: 2
Motif ID: 35
Motif name: INSM1
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Backward
Position number: 5
Number of overlap: 6
Similarity score: 0.0255256

Alignment:
TGYCAGGGGGCR
--KCAGAG----

Original motif     Consensus sequence: TGYCAGGGGGCR Reverse complement motif     Consensus sequence: MGCCCCCTGMCA


Dataset #: 2
Motif ID: 16
Motif name: SP1
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Backward
Position number: 5
Number of overlap: 6
Similarity score: 0.0349642

Alignment:
CCCCKCCCCC
CTCTGY----

Original motif     Consensus sequence: CCCCKCCCCC Reverse complement motif     Consensus sequence: GGGGGYGGGG


Dataset #: 2
Motif ID: 19
Motif name: REST
Matching format of first motif: Original Motif
Matching format of second motif: Reverse Complement
Direction: Forward
Position number: 3
Number of overlap: 6
Similarity score: 0.0376108

Alignment:
GGYGCTGTCCATGGTGCTGAA
--CTCTGY-------------

Original motif     Consensus sequence: TTCAGCACCATGGACAGCKCC Reverse complement motif     Consensus sequence: GGYGCTGTCCATGGTGCTGAA


Dataset #: 2
Motif ID: 12
Motif name: Zfx
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Forward
Position number: 4
Number of overlap: 6
Similarity score: 0.0448449

Alignment:
BBVGCCBVGGCCTV
---KCAGAG-----

Original motif     Consensus sequence: BBVGCCBVGGCCTV Reverse complement motif     Consensus sequence: VAGGCCBBGGCVBB


Dataset #: 2
Motif ID: 29
Motif name: ESR1
Matching format of first motif: Reverse Complement
Matching format of second motif: Reverse Complement
Direction: Forward
Position number: 4
Number of overlap: 6
Similarity score: 0.0454269

Alignment:
MGGTCAGGGTGACCTRDBHV
---KCAGAG-----------

Original motif     Consensus sequence: VDBHMAGGTCACCCTGACCY Reverse complement motif     Consensus sequence: MGGTCAGGGTGACCTRDBHV


Dataset #: 1 Motif ID: 5 Motif name: Motif 5

Original motif     Consensus sequence: ATKTM Reverse complement motif     Consensus sequence: RARAT

Best Matches for Top Significant Motif ID 5 (Highest to Lowest)

Dataset #: 2
Motif ID: 18
Motif name: RREB1
Matching format of first motif: Reverse Complement
Matching format of second motif: Reverse Complement
Direction: Backward
Position number: 10
Number of overlap: 5
Similarity score: 0.0256083

Alignment:
BGRRRGRGGRTGRTTYGGGG
------RARAT---------

Original motif     Consensus sequence: CCCCMAAMCAMCCMCMMMCV Reverse complement motif     Consensus sequence: BGRRRGRGGRTGRTTYGGGG


Dataset #: 2
Motif ID: 44
Motif name: NR4A2
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Backward
Position number: 4
Number of overlap: 5
Similarity score: 0.0276382

Alignment:
AAGGTCAC
RARAT---

Original motif     Consensus sequence: AAGGTCAC Reverse complement motif     Consensus sequence: GTGACCTT


Dataset #: 2
Motif ID: 22
Motif name: NR2F1
Matching format of first motif: Reverse Complement
Matching format of second motif: Reverse Complement
Direction: Backward
Position number: 3
Number of overlap: 5
Similarity score: 0.0279129

Alignment:
AKGYYCAAAGRTCA
-------RARAT--

Original motif     Consensus sequence: TGAMCTTTGMMCYT Reverse complement motif     Consensus sequence: AKGYYCAAAGRTCA


Dataset #: 2
Motif ID: 37
Motif name: MIZF
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Backward
Position number: 4
Number of overlap: 5
Similarity score: 0.0292478

Alignment:
BAACGTCCGC
--ATKTM---

Original motif     Consensus sequence: BAACGTCCGC Reverse complement motif     Consensus sequence: GCGGACGTTV


Dataset #: 2
Motif ID: 43
Motif name: NR1H2RXRA
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Forward
Position number: 10
Number of overlap: 5
Similarity score: 0.0292478

Alignment:
AAAGGTCAAAGGTCAAC
---------ATKTM---

Original motif     Consensus sequence: AAAGGTCAAAGGTCAAC Reverse complement motif     Consensus sequence: GTTGACCTTTGACCTTT


Dataset #: 2
Motif ID: 20
Motif name: PPARGRXRA
Matching format of first motif: Original Motif
Matching format of second motif: Reverse Complement
Direction: Forward
Position number: 5
Number of overlap: 5
Similarity score: 0.0305369

Alignment:
TGRCCTKTGHCCKAB
----ATKTM------

Original motif     Consensus sequence: BTRGGDCARAGGKCA Reverse complement motif     Consensus sequence: TGRCCTKTGHCCKAB


Dataset #: 2
Motif ID: 19
Motif name: REST
Matching format of first motif: Original Motif
Matching format of second motif: Reverse Complement
Direction: Forward
Position number: 5
Number of overlap: 5
Similarity score: 0.0315454

Alignment:
GGYGCTGTCCATGGTGCTGAA
----ATKTM------------

Original motif     Consensus sequence: TTCAGCACCATGGACAGCKCC Reverse complement motif     Consensus sequence: GGYGCTGTCCATGGTGCTGAA


Dataset #: 2
Motif ID: 47
Motif name: RXRRAR_DR5
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Backward
Position number: 13
Number of overlap: 5
Similarity score: 0.0335956

Alignment:
RGKTCABVVRGAGGTCA
ATKTM------------

Original motif     Consensus sequence: RGKTCABVVRGAGGTCA Reverse complement motif     Consensus sequence: TGACCTCKVVBTGAYCK


Dataset #: 2
Motif ID: 46
Motif name: RORA_1
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Forward
Position number: 4
Number of overlap: 5
Similarity score: 0.0336052

Alignment:
AWVDAGGTCA
---RARAT--

Original motif     Consensus sequence: AWVDAGGTCA Reverse complement motif     Consensus sequence: TGACCTDVWT


Dataset #: 2
Motif ID: 34
Motif name: HNF4A
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Backward
Position number: 2
Number of overlap: 5
Similarity score: 0.0367105

Alignment:
RGGBCAAAGKYCA
-------ATKTM-

Original motif     Consensus sequence: RGGBCAAAGKYCA Reverse complement motif     Consensus sequence: TGMYCTTTGBCCK


Dataset #: 1 Motif ID: 6 Motif name: Motif 6

Original motif     Consensus sequence: CMGCRGC Reverse complement motif     Consensus sequence: GCKGCYG

Best Matches for Top Significant Motif ID 6 (Highest to Lowest)

Dataset #: 2
Motif ID: 19
Motif name: REST
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Backward
Position number: 13
Number of overlap: 7
Similarity score: 0.0205607

Alignment:
TTCAGCACCATGGACAGCKCC
--CMGCRGC------------

Original motif     Consensus sequence: TTCAGCACCATGGACAGCKCC Reverse complement motif     Consensus sequence: GGYGCTGTCCATGGTGCTGAA


Dataset #: 2
Motif ID: 37
Motif name: MIZF
Matching format of first motif: Reverse Complement
Matching format of second motif: Reverse Complement
Direction: Forward
Position number: 1
Number of overlap: 7
Similarity score: 0.0322623

Alignment:
GCGGACGTTV
GCKGCYG---

Original motif     Consensus sequence: BAACGTCCGC Reverse complement motif     Consensus sequence: GCGGACGTTV


Dataset #: 2
Motif ID: 12
Motif name: Zfx
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Forward
Position number: 5
Number of overlap: 7
Similarity score: 0.038091

Alignment:
BBVGCCBVGGCCTV
----CMGCRGC---

Original motif     Consensus sequence: BBVGCCBVGGCCTV Reverse complement motif     Consensus sequence: VAGGCCBBGGCVBB


Dataset #: 2
Motif ID: 15
Motif name: TFAP2A
Matching format of first motif: Original Motif
Matching format of second motif: Reverse Complement
Direction: Forward
Position number: 3
Number of overlap: 7
Similarity score: 0.0393168

Alignment:
SCMVBBGGC
--CMGCRGC

Original motif     Consensus sequence: GCCBBVRGS Reverse complement motif     Consensus sequence: SCMVBBGGC


Dataset #: 2
Motif ID: 45
Motif name: Pax5
Matching format of first motif: Reverse Complement
Matching format of second motif: Reverse Complement
Direction: Backward
Position number: 7
Number of overlap: 7
Similarity score: 0.0448462

Alignment:
MSGKKRCGCWDCABTGBBCD
-------GCKGCYG------

Original motif     Consensus sequence: DGVBCABTGDWGCGKRRCSR Reverse complement motif     Consensus sequence: MSGKKRCGCWDCABTGBBCD


Dataset #: 2
Motif ID: 28
Motif name: Egr1
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Backward
Position number: 2
Number of overlap: 7
Similarity score: 0.0453576

Alignment:
HGCGTGGGCGK
---GCKGCYG-

Original motif     Consensus sequence: HGCGTGGGCGK Reverse complement motif     Consensus sequence: YCGCCCACGCH


Dataset #: 2
Motif ID: 36
Motif name: Klf4
Matching format of first motif: Original Motif
Matching format of second motif: Reverse Complement
Direction: Forward
Position number: 2
Number of overlap: 7
Similarity score: 0.0476958

Alignment:
GCCYCMCCCD
-CMGCRGC--

Original motif     Consensus sequence: DGGGYGKGGC Reverse complement motif     Consensus sequence: GCCYCMCCCD


Dataset #: 2
Motif ID: 16
Motif name: SP1
Matching format of first motif: Reverse Complement
Matching format of second motif: Reverse Complement
Direction: Forward
Position number: 1
Number of overlap: 7
Similarity score: 0.0490991

Alignment:
GGGGGYGGGG
GCKGCYG---

Original motif     Consensus sequence: CCCCKCCCCC Reverse complement motif     Consensus sequence: GGGGGYGGGG


Dataset #: 2
Motif ID: 18
Motif name: RREB1
Matching format of first motif: Reverse Complement
Matching format of second motif: Reverse Complement
Direction: Forward
Position number: 6
Number of overlap: 7
Similarity score: 0.0498726

Alignment:
BGRRRGRGGRTGRTTYGGGG
-----GCKGCYG--------

Original motif     Consensus sequence: CCCCMAAMCAMCCMCMMMCV Reverse complement motif     Consensus sequence: BGRRRGRGGRTGRTTYGGGG


Dataset #: 2
Motif ID: 35
Motif name: INSM1
Matching format of first motif: Original Motif
Matching format of second motif: Reverse Complement
Direction: Backward
Position number: 3
Number of overlap: 7
Similarity score: 0.0511926

Alignment:
MGCCCCCTGMCA
---CMGCRGC--

Original motif     Consensus sequence: TGYCAGGGGGCR Reverse complement motif     Consensus sequence: MGCCCCCTGMCA


Dataset #: 1 Motif ID: 8 Motif name: Motif 8

Original motif     Consensus sequence: CTGGGA Reverse complement motif     Consensus sequence: TCCCAG

Best Matches for Top Significant Motif ID 8 (Highest to Lowest)

Dataset #: 2
Motif ID: 19
Motif name: REST
Matching format of first motif: Reverse Complement
Matching format of second motif: Reverse Complement
Direction: Backward
Position number: 9
Number of overlap: 6
Similarity score: 0.0392549

Alignment:
GGYGCTGTCCATGGTGCTGAA
-------TCCCAG--------

Original motif     Consensus sequence: TTCAGCACCATGGACAGCKCC Reverse complement motif     Consensus sequence: GGYGCTGTCCATGGTGCTGAA


Dataset #: 2
Motif ID: 23
Motif name: MZF1_1-4
Matching format of first motif: Reverse Complement
Matching format of second motif: Reverse Complement
Direction: Forward
Position number: 1
Number of overlap: 6
Similarity score: 0.0416319

Alignment:
TCCCCV
TCCCAG

Original motif     Consensus sequence: BGGGGA Reverse complement motif     Consensus sequence: TCCCCV


Dataset #: 2
Motif ID: 18
Motif name: RREB1
Matching format of first motif: Original Motif
Matching format of second motif: Reverse Complement
Direction: Backward
Position number: 1
Number of overlap: 6
Similarity score: 0.0509122

Alignment:
BGRRRGRGGRTGRTTYGGGG
--------------CTGGGA

Original motif     Consensus sequence: CCCCMAAMCAMCCMCMMMCV Reverse complement motif     Consensus sequence: BGRRRGRGGRTGRTTYGGGG


Dataset #: 2
Motif ID: 35
Motif name: INSM1
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Forward
Position number: 4
Number of overlap: 6
Similarity score: 0.0557857

Alignment:
TGYCAGGGGGCR
---CTGGGA---

Original motif     Consensus sequence: TGYCAGGGGGCR Reverse complement motif     Consensus sequence: MGCCCCCTGMCA


Dataset #: 2
Motif ID: 13
Motif name: Zfp423
Matching format of first motif: Reverse Complement
Matching format of second motif: Reverse Complement
Direction: Backward
Position number: 7
Number of overlap: 6
Similarity score: 0.0624145

Alignment:
GYRYCCMTKGGYRSC
---TCCCAG------

Original motif     Consensus sequence: GSMMCCYARGGKKKC Reverse complement motif     Consensus sequence: GYRYCCMTKGGYRSC


Dataset #: 2
Motif ID: 43
Motif name: NR1H2RXRA
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Backward
Position number: 7
Number of overlap: 6
Similarity score: 0.0650784

Alignment:
AAAGGTCAAAGGTCAAC
-----TCCCAG------

Original motif     Consensus sequence: AAAGGTCAAAGGTCAAC Reverse complement motif     Consensus sequence: GTTGACCTTTGACCTTT


Dataset #: 2
Motif ID: 48
Motif name: Tcfcp2l1
Matching format of first motif: Original Motif
Matching format of second motif: Reverse Complement
Direction: Backward
Position number: 9
Number of overlap: 6
Similarity score: 0.0663804

Alignment:
CKGGDTBDMMCTGG
CTGGGA--------

Original motif     Consensus sequence: CCAGYYHVADCCRG Reverse complement motif     Consensus sequence: CKGGDTBDMMCTGG


Dataset #: 2
Motif ID: 28
Motif name: Egr1
Matching format of first motif: Reverse Complement
Matching format of second motif: Reverse Complement
Direction: Forward
Position number: 3
Number of overlap: 6
Similarity score: 0.0678562

Alignment:
YCGCCCACGCH
--TCCCAG---

Original motif     Consensus sequence: HGCGTGGGCGK Reverse complement motif     Consensus sequence: YCGCCCACGCH


Dataset #: 2
Motif ID: 24
Motif name: Ar
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Backward
Position number: 3
Number of overlap: 6
Similarity score: 0.0714107

Alignment:
HWDAGHACRHHVTGTHCCHVMV
--------------TCCCAG--

Original motif     Consensus sequence: HWDAGHACRHHVTGTHCCHVMV Reverse complement motif     Consensus sequence: VRVDGGHACAVDDKGTHCTDWH


Dataset #: 2
Motif ID: 12
Motif name: Zfx
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Backward
Position number: 4
Number of overlap: 6
Similarity score: 0.0718041

Alignment:
BBVGCCBVGGCCTV
-----CTGGGA---

Original motif     Consensus sequence: BBVGCCBVGGCCTV Reverse complement motif     Consensus sequence: VAGGCCBBGGCVBB


Dataset #: 1 Motif ID: 2 Motif name: Motif 2

Original motif     Consensus sequence: AMACA Reverse complement motif     Consensus sequence: TGTRT

Best Matches for Top Significant Motif ID 2 (Highest to Lowest)

Dataset #: 2
Motif ID: 18
Motif name: RREB1
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Backward
Position number: 11
Number of overlap: 5
Similarity score: 0.0243918

Alignment:
CCCCMAAMCAMCCMCMMMCV
-----AMACA----------

Original motif     Consensus sequence: CCCCMAAMCAMCCMCMMMCV Reverse complement motif     Consensus sequence: BGRRRGRGGRTGRTTYGGGG


Dataset #: 2
Motif ID: 24
Motif name: Ar
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Backward
Position number: 14
Number of overlap: 5
Similarity score: 0.0429089

Alignment:
HWDAGHACRHHVTGTHCCHVMV
----AMACA-------------

Original motif     Consensus sequence: HWDAGHACRHHVTGTHCCHVMV Reverse complement motif     Consensus sequence: VRVDGGHACAVDDKGTHCTDWH


Dataset #: 2
Motif ID: 20
Motif name: PPARGRXRA
Matching format of first motif: Reverse Complement
Matching format of second motif: Reverse Complement
Direction: Backward
Position number: 6
Number of overlap: 5
Similarity score: 0.0595073

Alignment:
TGRCCTKTGHCCKAB
-----TGTRT-----

Original motif     Consensus sequence: BTRGGDCARAGGKCA Reverse complement motif     Consensus sequence: TGRCCTKTGHCCKAB


Dataset #: 2
Motif ID: 26
Motif name: ArntAhr
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Forward
Position number: 1
Number of overlap: 5
Similarity score: 0.0600161

Alignment:
YGCGTG
TGTRT-

Original motif     Consensus sequence: YGCGTG Reverse complement motif     Consensus sequence: CACGCM


Dataset #: 2
Motif ID: 45
Motif name: Pax5
Matching format of first motif: Original Motif
Matching format of second motif: Reverse Complement
Direction: Forward
Position number: 6
Number of overlap: 5
Similarity score: 0.0620995

Alignment:
MSGKKRCGCWDCABTGBBCD
-----AMACA----------

Original motif     Consensus sequence: DGVBCABTGDWGCGKRRCSR Reverse complement motif     Consensus sequence: MSGKKRCGCWDCABTGBBCD


Dataset #: 2
Motif ID: 22
Motif name: NR2F1
Matching format of first motif: Original Motif
Matching format of second motif: Reverse Complement
Direction: Backward
Position number: 4
Number of overlap: 5
Similarity score: 0.0650242

Alignment:
AKGYYCAAAGRTCA
------AMACA---

Original motif     Consensus sequence: TGAMCTTTGMMCYT Reverse complement motif     Consensus sequence: AKGYYCAAAGRTCA


Dataset #: 2
Motif ID: 35
Motif name: INSM1
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Backward
Position number: 8
Number of overlap: 5
Similarity score: 0.0670984

Alignment:
TGYCAGGGGGCR
TGTRT-------

Original motif     Consensus sequence: TGYCAGGGGGCR Reverse complement motif     Consensus sequence: MGCCCCCTGMCA


Dataset #: 2
Motif ID: 33
Motif name: HIF1AARNT
Matching format of first motif: Original Motif
Matching format of second motif: Reverse Complement
Direction: Backward
Position number: 4
Number of overlap: 5
Similarity score: 0.0700905

Alignment:
VCACGTBV
AMACA---

Original motif     Consensus sequence: VBACGTGV Reverse complement motif     Consensus sequence: VCACGTBV


Dataset #: 2
Motif ID: 38
Motif name: Myc
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Backward
Position number: 5
Number of overlap: 5
Similarity score: 0.0708148

Alignment:
VGCACGTGGH
-AMACA----

Original motif     Consensus sequence: VGCACGTGGH Reverse complement motif     Consensus sequence: DCCACGTGCV


Dataset #: 2
Motif ID: 34
Motif name: HNF4A
Matching format of first motif: Reverse Complement
Matching format of second motif: Reverse Complement
Direction: Backward
Position number: 4
Number of overlap: 5
Similarity score: 0.071574

Alignment:
TGMYCTTTGBCCK
-----TGTRT---

Original motif     Consensus sequence: RGGBCAAAGKYCA Reverse complement motif     Consensus sequence: TGMYCTTTGBCCK


Dataset #: 1 Motif ID: 3 Motif name: Motif 3

Original motif     Consensus sequence: AGSCWGG Reverse complement motif     Consensus sequence: CCWGSCT

Best Matches for Top Significant Motif ID 3 (Highest to Lowest)

Dataset #: 2
Motif ID: 32
Motif name: EWSR1-FLI1
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Forward
Position number: 8
Number of overlap: 7
Similarity score: 0.0395671

Alignment:
GGAAGGAAGGAAGGAAGG
-------AGSCWGG----

Original motif     Consensus sequence: GGAAGGAAGGAAGGAAGG Reverse complement motif     Consensus sequence: CCTTCCTTCCTTCCTTCC


Dataset #: 2
Motif ID: 35
Motif name: INSM1
Matching format of first motif: Reverse Complement
Matching format of second motif: Reverse Complement
Direction: Backward
Position number: 1
Number of overlap: 7
Similarity score: 0.0494688

Alignment:
MGCCCCCTGMCA
-----CCWGSCT

Original motif     Consensus sequence: TGYCAGGGGGCR Reverse complement motif     Consensus sequence: MGCCCCCTGMCA


Dataset #: 2
Motif ID: 48
Motif name: Tcfcp2l1
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Forward
Position number: 1
Number of overlap: 7
Similarity score: 0.0669354

Alignment:
CCAGYYHVADCCRG
CCWGSCT-------

Original motif     Consensus sequence: CCAGYYHVADCCRG Reverse complement motif     Consensus sequence: CKGGDTBDMMCTGG


Dataset #: 2
Motif ID: 19
Motif name: REST
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Backward
Position number: 9
Number of overlap: 7
Similarity score: 0.0693747

Alignment:
TTCAGCACCATGGACAGCKCC
------AGSCWGG--------

Original motif     Consensus sequence: TTCAGCACCATGGACAGCKCC Reverse complement motif     Consensus sequence: GGYGCTGTCCATGGTGCTGAA


Dataset #: 2
Motif ID: 16
Motif name: SP1
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Backward
Position number: 3
Number of overlap: 7
Similarity score: 0.0695377

Alignment:
CCCCKCCCCC
-CCWGSCT--

Original motif     Consensus sequence: CCCCKCCCCC Reverse complement motif     Consensus sequence: GGGGGYGGGG


Dataset #: 2
Motif ID: 12
Motif name: Zfx
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Backward
Position number: 2
Number of overlap: 7
Similarity score: 0.0720685

Alignment:
BBVGCCBVGGCCTV
------CCWGSCT-

Original motif     Consensus sequence: BBVGCCBVGGCCTV Reverse complement motif     Consensus sequence: VAGGCCBBGGCVBB


Dataset #: 2
Motif ID: 29
Motif name: ESR1
Matching format of first motif: Reverse Complement
Matching format of second motif: Reverse Complement
Direction: Forward
Position number: 13
Number of overlap: 7
Similarity score: 0.0771405

Alignment:
MGGTCAGGGTGACCTRDBHV
------------CCWGSCT-

Original motif     Consensus sequence: VDBHMAGGTCACCCTGACCY Reverse complement motif     Consensus sequence: MGGTCAGGGTGACCTRDBHV


Dataset #: 2
Motif ID: 46
Motif name: RORA_1
Matching format of first motif: Reverse Complement
Matching format of second motif: Reverse Complement
Direction: Backward
Position number: 1
Number of overlap: 7
Similarity score: 0.0772276

Alignment:
TGACCTDVWT
---CCWGSCT

Original motif     Consensus sequence: AWVDAGGTCA Reverse complement motif     Consensus sequence: TGACCTDVWT


Dataset #: 2
Motif ID: 36
Motif name: Klf4
Matching format of first motif: Reverse Complement
Matching format of second motif: Reverse Complement
Direction: Backward
Position number: 1
Number of overlap: 7
Similarity score: 0.0798994

Alignment:
GCCYCMCCCD
---CCWGSCT

Original motif     Consensus sequence: DGGGYGKGGC Reverse complement motif     Consensus sequence: GCCYCMCCCD


Dataset #: 2
Motif ID: 39
Motif name: MYCMAX
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Backward
Position number: 5
Number of overlap: 7
Similarity score: 0.0839075

Alignment:
RASCACGTGGT
AGSCWGG----

Original motif     Consensus sequence: RASCACGTGGT Reverse complement motif     Consensus sequence: ACCACGTGSTM


Dataset #: 1 Motif ID: 1 Motif name: Motif 1

Original motif     Consensus sequence: RGGAAR Reverse complement motif     Consensus sequence: MTTCCK

Best Matches for Top Significant Motif ID 1 (Highest to Lowest)

Dataset #: 2
Motif ID: 32
Motif name: EWSR1-FLI1
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Forward
Position number: 12
Number of overlap: 6
Similarity score: 0.0146511

Alignment:
GGAAGGAAGGAAGGAAGG
-----------RGGAAR-

Original motif     Consensus sequence: GGAAGGAAGGAAGGAAGG Reverse complement motif     Consensus sequence: CCTTCCTTCCTTCCTTCC


Dataset #: 2
Motif ID: 37
Motif name: MIZF
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Forward
Position number: 4
Number of overlap: 6
Similarity score: 0.0608243

Alignment:
BAACGTCCGC
---MTTCCK-

Original motif     Consensus sequence: BAACGTCCGC Reverse complement motif     Consensus sequence: GCGGACGTTV


Dataset #: 2
Motif ID: 41
Motif name: MZF1_5-13
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Backward
Position number: 1
Number of overlap: 6
Similarity score: 0.0753789

Alignment:
BKAGGGGDAD
----RGGAAR

Original motif     Consensus sequence: BKAGGGGDAD Reverse complement motif     Consensus sequence: BTHCCCCTYB


Dataset #: 2
Motif ID: 42
Motif name: NFKB1
Matching format of first motif: Original Motif
Matching format of second motif: Reverse Complement
Direction: Forward
Position number: 2
Number of overlap: 6
Similarity score: 0.0757695

Alignment:
GGGGAAKCCCC
-RGGAAR----

Original motif     Consensus sequence: GGGGRTTCCCC Reverse complement motif     Consensus sequence: GGGGAAKCCCC


Dataset #: 2
Motif ID: 20
Motif name: PPARGRXRA
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Backward
Position number: 7
Number of overlap: 6
Similarity score: 0.0800484

Alignment:
BTRGGDCARAGGKCA
---RGGAAR------

Original motif     Consensus sequence: BTRGGDCARAGGKCA Reverse complement motif     Consensus sequence: TGRCCTKTGHCCKAB


Dataset #: 2
Motif ID: 19
Motif name: REST
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Backward
Position number: 6
Number of overlap: 6
Similarity score: 0.0829223

Alignment:
TTCAGCACCATGGACAGCKCC
----------RGGAAR-----

Original motif     Consensus sequence: TTCAGCACCATGGACAGCKCC Reverse complement motif     Consensus sequence: GGYGCTGTCCATGGTGCTGAA


Dataset #: 2
Motif ID: 35
Motif name: INSM1
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Forward
Position number: 7
Number of overlap: 6
Similarity score: 0.0832926

Alignment:
TGYCAGGGGGCR
------RGGAAR

Original motif     Consensus sequence: TGYCAGGGGGCR Reverse complement motif     Consensus sequence: MGCCCCCTGMCA


Dataset #: 2
Motif ID: 18
Motif name: RREB1
Matching format of first motif: Original Motif
Matching format of second motif: Reverse Complement
Direction: Forward
Position number: 5
Number of overlap: 6
Similarity score: 0.0835516

Alignment:
BGRRRGRGGRTGRTTYGGGG
----RGGAAR----------

Original motif     Consensus sequence: CCCCMAAMCAMCCMCMMMCV Reverse complement motif     Consensus sequence: BGRRRGRGGRTGRTTYGGGG


Dataset #: 2
Motif ID: 24
Motif name: Ar
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Forward
Position number: 4
Number of overlap: 6
Similarity score: 0.0836451

Alignment:
HWDAGHACRHHVTGTHCCHVMV
---RGGAAR-------------

Original motif     Consensus sequence: HWDAGHACRHHVTGTHCCHVMV Reverse complement motif     Consensus sequence: VRVDGGHACAVDDKGTHCTDWH


Dataset #: 2
Motif ID: 27
Motif name: E2F1
Matching format of first motif: Original Motif
Matching format of second motif: Reverse Complement
Direction: Backward
Position number: 1
Number of overlap: 6
Similarity score: 0.0842331

Alignment:
GCGCSAAA
--RGGAAR

Original motif     Consensus sequence: TTTSGCGC Reverse complement motif     Consensus sequence: GCGCSAAA


Dataset #: 2
Motif ID: 13
Motif name: Zfp423
Matching format of first motif: Original Motif
Matching format of second motif: Reverse Complement
Direction: Backward
Position number: 2
Number of overlap: 6
Similarity score: 0.0850287

Alignment:
GYRYCCMTKGGYRSC
--------RGGAAR-

Original motif     Consensus sequence: GSMMCCYARGGKKKC Reverse complement motif     Consensus sequence: GYRYCCMTKGGYRSC


Dataset #: 1 Motif ID: 7 Motif name: Motif 7

Original motif     Consensus sequence: CCCRCCCC Reverse complement motif     Consensus sequence: GGGGMGGG

Best Matches for Top Significant Motif ID 7 (Highest to Lowest)

Dataset #: 2
Motif ID: 16
Motif name: SP1
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Backward
Position number: 2
Number of overlap: 8
Similarity score: 0.0423611

Alignment:
CCCCKCCCCC
-CCCRCCCC-

Original motif     Consensus sequence: CCCCKCCCCC Reverse complement motif     Consensus sequence: GGGGGYGGGG


Dataset #: 2
Motif ID: 36
Motif name: Klf4
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Forward
Position number: 1
Number of overlap: 8
Similarity score: 0.0461644

Alignment:
DGGGYGKGGC
GGGGMGGG--

Original motif     Consensus sequence: DGGGYGKGGC Reverse complement motif     Consensus sequence: GCCYCMCCCD


Dataset #: 2
Motif ID: 28
Motif name: Egr1
Matching format of first motif: Original Motif
Matching format of second motif: Reverse Complement
Direction: Forward
Position number: 4
Number of overlap: 8
Similarity score: 0.0650374

Alignment:
YCGCCCACGCH
---CCCRCCCC

Original motif     Consensus sequence: HGCGTGGGCGK Reverse complement motif     Consensus sequence: YCGCCCACGCH


Dataset #: 2
Motif ID: 18
Motif name: RREB1
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Forward
Position number: 2
Number of overlap: 8
Similarity score: 0.076401

Alignment:
CCCCMAAMCAMCCMCMMMCV
-CCCRCCCC-----------

Original motif     Consensus sequence: CCCCMAAMCAMCCMCMMMCV Reverse complement motif     Consensus sequence: BGRRRGRGGRTGRTTYGGGG


Dataset #: 2
Motif ID: 42
Motif name: NFKB1
Matching format of first motif: Reverse Complement
Matching format of second motif: Reverse Complement
Direction: Forward
Position number: 1
Number of overlap: 8
Similarity score: 0.0893429

Alignment:
GGGGAAKCCCC
GGGGMGGG---

Original motif     Consensus sequence: GGGGRTTCCCC Reverse complement motif     Consensus sequence: GGGGAAKCCCC


Dataset #: 2
Motif ID: 35
Motif name: INSM1
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Forward
Position number: 1
Number of overlap: 8
Similarity score: 0.0936832

Alignment:
TGYCAGGGGGCR
GGGGMGGG----

Original motif     Consensus sequence: TGYCAGGGGGCR Reverse complement motif     Consensus sequence: MGCCCCCTGMCA


Dataset #: 2
Motif ID: 32
Motif name: EWSR1-FLI1
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Backward
Position number: 5
Number of overlap: 8
Similarity score: 0.0950969

Alignment:
GGAAGGAAGGAAGGAAGG
------GGGGMGGG----

Original motif     Consensus sequence: GGAAGGAAGGAAGGAAGG Reverse complement motif     Consensus sequence: CCTTCCTTCCTTCCTTCC


Dataset #: 2
Motif ID: 21
Motif name: PLAG1
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Forward
Position number: 1
Number of overlap: 8
Similarity score: 0.0998932

Alignment:
GGGGCCCAAGGGGG
GGGGMGGG------

Original motif     Consensus sequence: GGGGCCCAAGGGGG Reverse complement motif     Consensus sequence: CCCCCTTGGGCCCC


Dataset #: 2
Motif ID: 12
Motif name: Zfx
Matching format of first motif: Original Motif
Matching format of second motif: Original Motif
Direction: Forward
Position number: 5
Number of overlap: 8
Similarity score: 0.10221

Alignment:
BBVGCCBVGGCCTV
----CCCRCCCC--

Original motif     Consensus sequence: BBVGCCBVGGCCTV Reverse complement motif     Consensus sequence: VAGGCCBBGGCVBB


Dataset #: 2
Motif ID: 45
Motif name: Pax5
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Backward
Position number: 5
Number of overlap: 8
Similarity score: 0.102497

Alignment:
DGVBCABTGDWGCGKRRCSR
--------GGGGMGGG----

Original motif     Consensus sequence: DGVBCABTGDWGCGKRRCSR Reverse complement motif     Consensus sequence: MSGKKRCGCWDCABTGBBCD


Dataset #: 2 Motif ID: 26 Motif name: ArntAhr

Original motif     Consensus sequence: YGCGTG Reverse complement motif     Consensus sequence: CACGCM

Best Matches for Top Significant Motif ID 26 (Highest to Lowest)

Dataset #: 1
Motif ID: 11
Motif name: Motif 11
Matching format of first motif: Original Motif
Matching format of second motif: Reverse Complement
Direction: Forward
Position number: 7
Number of overlap: 6
Similarity score: 0.0308396

Alignment:
TGTGTGTGTGTKTG
------YGCGTG--

Original motif     Consensus sequence: CAYACACACACACA Reverse complement motif     Consensus sequence: TGTGTGTGTGTKTG


Dataset #: 1
Motif ID: 9
Motif name: Motif 9
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Backward
Position number: 1
Number of overlap: 6
Similarity score: 0.0350575

Alignment:
CACACAVRCACACA
--------CACGCM

Original motif     Consensus sequence: CACACAVRCACACA Reverse complement motif     Consensus sequence: TGTGTGKVTGTGTG


Dataset #: 1
Motif ID: 7
Motif name: Motif 7
Matching format of first motif: Original Motif
Matching format of second motif: Reverse Complement
Direction: Backward
Position number: 3
Number of overlap: 6
Similarity score: 0.0586538

Alignment:
GGGGMGGG
YGCGTG--

Original motif     Consensus sequence: CCCRCCCC Reverse complement motif     Consensus sequence: GGGGMGGG


Dataset #: 1
Motif ID: 3
Motif name: Motif 3
Matching format of first motif: Reverse Complement
Matching format of second motif: Reverse Complement
Direction: Forward
Position number: 2
Number of overlap: 6
Similarity score: 0.0884818

Alignment:
CCWGSCT
-CACGCM

Original motif     Consensus sequence: AGSCWGG Reverse complement motif     Consensus sequence: CCWGSCT


Dataset #: 1
Motif ID: 2
Motif name: Motif 2
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Forward
Position number: 1
Number of overlap: 5
Similarity score: 0.563057

Alignment:
AMACA-
CACGCM

Original motif     Consensus sequence: AMACA Reverse complement motif     Consensus sequence: TGTRT


Dataset #: 1
Motif ID: 6
Motif name: Motif 6
Matching format of first motif: Original Motif
Matching format of second motif: Reverse Complement
Direction: Backward
Position number: 3
Number of overlap: 5
Similarity score: 0.572774

Alignment:
-GCKGCYG
YGCGTG--

Original motif     Consensus sequence: CMGCRGC Reverse complement motif     Consensus sequence: GCKGCYG


Dataset #: 1
Motif ID: 8
Motif name: Motif 8
Matching format of first motif: Reverse Complement
Matching format of second motif: Reverse Complement
Direction: Backward
Position number: 2
Number of overlap: 5
Similarity score: 0.581904

Alignment:
-TCCCAG
CACGCM-

Original motif     Consensus sequence: CTGGGA Reverse complement motif     Consensus sequence: TCCCAG


Dataset #: 1
Motif ID: 4
Motif name: Motif 4
Matching format of first motif: Original Motif
Matching format of second motif: Reverse Complement
Direction: Backward
Position number: 3
Number of overlap: 4
Similarity score: 1.06919

Alignment:
--KCAGAG
YGCGTG--

Original motif     Consensus sequence: CTCTGY Reverse complement motif     Consensus sequence: KCAGAG


Dataset #: 2 Motif ID: 33 Motif name: HIF1AARNT

Original motif     Consensus sequence: VBACGTGV Reverse complement motif     Consensus sequence: VCACGTBV

Best Matches for Top Significant Motif ID 33 (Highest to Lowest)

Dataset #: 1
Motif ID: 9
Motif name: Motif 9
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Backward
Position number: 2
Number of overlap: 8
Similarity score: 0.0745994

Alignment:
CACACAVRCACACA
-----VCACGTBV-

Original motif     Consensus sequence: CACACAVRCACACA Reverse complement motif     Consensus sequence: TGTGTGKVTGTGTG


Dataset #: 1
Motif ID: 11
Motif name: Motif 11
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Forward
Position number: 4
Number of overlap: 8
Similarity score: 0.0850889

Alignment:
CAYACACACACACA
---VCACGTBV---

Original motif     Consensus sequence: CAYACACACACACA Reverse complement motif     Consensus sequence: TGTGTGTGTGTKTG


Dataset #: 1
Motif ID: 7
Motif name: Motif 7
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Forward
Position number: 2
Number of overlap: 7
Similarity score: 0.588622

Alignment:
CCCRCCCC-
-VCACGTBV

Original motif     Consensus sequence: CCCRCCCC Reverse complement motif     Consensus sequence: GGGGMGGG


Dataset #: 1
Motif ID: 3
Motif name: Motif 3
Matching format of first motif: Reverse Complement
Matching format of second motif: Original Motif
Direction: Backward
Position number: 3
Number of overlap: 5
Similarity score: 1.55675

Alignment:
---AGSCWGG
VCACGTBV--

Original motif     Consensus sequence: AGSCWGG Reverse complement motif     Consensus sequence: CCWGSCT


Dataset #: 1
Motif ID: 2
Motif name: Motif 2
Matching format of first motif: Original Motif
Matching format of second motif: Reverse Complement
Direction: Forward
Position number: 1
Number of overlap: 5
Similarity score: 1.57238

Alignment:
TGTRT---
VBACGTGV

Original motif     Consensus sequence: AMACA Reverse complement motif     Consensus sequence: TGTRT


Results created by MOTIFSIM on 11-20-2016 21:31:13
Runtime: 756.479 seconds

MOTIFSIM is written by Ngoc Tam L. Tran
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