**************************************************************************************************************************************************************************************************** MOTIFSIM - Motif Similarity Detection Tool Version 2.2 **************************************************************************************************************************************************************************************************** INPUT **************************************************************************************************************************************************************************************************** Input Parameters Number of files: 4 Number of top significant motifs: 10 Number of best matches: 10 Similarity cutoff: >= 0.75 Matching motif database: UniProbe Mus Musculus Motif tree: Yes Combined similar motifs: Yes Output file type: All Output file format: All Input files and motif counts File name Count of motifs Dataset # DREME_DM721.txt 16 1 MEME-ChIP_DM721.txt 11 2 PScanChIP_DM721.txt 37 3 RSAT_peak-motifs_DM721.txt 40 4 **************************************************************************************************************************************************************************************************** RESULTS **************************************************************************************************************************************************************************************************** *************************************************************** Combined Motifs for Top Best Match Motif ID 1 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 1 AAAAAAAAAAA Original Motif Original Motif AAAAWAAA AAAAAAAAAAA AAAAAAAAAAA Direction: Backward Position #: 2 Overlap #: 8 Alignment: --AAAAWAAA- AAAAAAAAAAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 5 Original Motif Original Motif AAAAAAAAAAA AAAASAAA AAAAMAAAAAA Direction: Forward Position #: 1 Overlap #: 8 Alignment: AAAAAAAAAAA AAAASAAA--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwWAAAAAwa Original Motif Original Motif AAAAMAAAAAA WWAAAAAAWH AAAAAAAAWAA Direction: Forward Position #: 1 Overlap #: 10 Alignment: AAAAMAAAAAA WWAAAAAAWH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 26 Combined Motif Original Motif Reverse Complement AAAAAAAAWAA AAAAAAACAAARRA AAAAAAAAHAAARRA Direction: Forward Position #: 2 Overlap #: 10 Alignment: AAAAAAAAWAA---- -AAAAAAACAAARRA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTAAwAAww Original Motif Original Motif AAAAAAAAHAAARRA DDTAAWAAHH DAWAAAAAHAAARRA Direction: Forward Position #: 1 Overlap #: 10 Alignment: AAAAAAAAHAAARRA DDTAAWAAHH----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- aaCAAAAACaa Combined Motif Reverse Complement Reverse Complement TKKTTTHTTTTTWTD HTGTTTTTGHH TKTTKTTTTTKTWTD Direction: Forward Position #: 3 Overlap #: 11 Alignment: TKKTTTHTTTTTWTD --HTGTTTTTGHH-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTAAAwAww Reverse Complement Original Motif DAWAYAAAAAYAARA DDTAAAWAHH DATAMAAAHAYAARA Direction: Forward Position #: 1 Overlap #: 10 Alignment: DAWAYAAAAAYAARA DDTAAAWAHH----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtATTTTTAww Original Motif Reverse Complement DATAMAAAHAYAARA DDTAAAAATHD DDTAAAAATHHAARA Direction: Forward Position #: 1 Overlap #: 11 Alignment: DATAMAAAHAYAARA DDTAAAAATHD---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif aaACAAAACaa Original Motif Original Motif DDTAAAAATHHAARA AAACAAAACAA DHWMAAAAYAHAARA Direction: Forward Position #: 1 Overlap #: 11 Alignment: DDTAAAAATHHAARA AAACAAAACAA---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif tyTCTkTkTCyy Original Motif Reverse Complement DHWMAAAAYAHAARA VHGARAYAGAVV HHRAAAHASAHAARA Direction: Forward Position #: 1 Overlap #: 12 Alignment: DHWMAAAAYAHAARA VHGARAYAGAVV--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yayAyAyACATrya Original Motif Original Motif HHRAAAHASAHAARA HACAYAYACATRHD HHBAHAYACATRHRA Direction: Forward Position #: 1 Overlap #: 14 Alignment: HHRAAAHASAHAARA HACAYAYACATRHD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 2 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 2 CACACACACACA Original Motif Original Motif CACACACA CACACACACACA CACACACACACA Direction: Forward Position #: 3 Overlap #: 8 Alignment: --CACACACA-- CACACACACACA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACACACACACA Reverse Complement Reverse Complement TGTGTGTGTGTG TGTGTGTGTGTG TGTGTGTGTGTG Direction: Forward Position #: 1 Overlap #: 12 Alignment: TGTGTGTGTGTG TGTGTGTGTGTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 27 Original Motif Reverse Complement TGTGTGTGTGTG TGTGTGTGTGTKTG TGTGTGTGTGTGTG Direction: Forward Position #: 1 Overlap #: 12 Alignment: TGTGTGTGTGTG-- TGTGTGTGTGTKTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 25 Reverse Complement Original Motif CACACACACACACA CACACAVRCACACA CACACACACACACA Direction: Forward Position #: 1 Overlap #: 14 Alignment: CACACACACACACA CACACAVRCACACA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ryayAyAyrtGTRTrTry Reverse Complement Original Motif TGTGTGTGTGTGTG DHAYAYAYRTGTGTRTDH DTRTRYRTRTGTGTGTDH Direction: Forward Position #: 2 Overlap #: 14 Alignment: -TGTGTGTGTGTGTG--- DHAYAYAYRTGTGTRTDH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yayAyAyACATrya Reverse Complement Original Motif HDACACACAMAKMMAMAD HACAYAYACATRHD HVBACACACAYRBAMAMAD Direction: Forward Position #: 2 Overlap #: 13 Alignment: -HDACACACAMAKMMAMAD HACAYAYACATRHD----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif aaCAAAAACaa Original Motif Original Motif HVBACACACAYRBAMAMAD HHCAAAAACAH HHCAMAMACAHRBAMAMAD Direction: Forward Position #: 1 Overlap #: 11 Alignment: HVBACACACAYRBAMAMAD HHCAAAAACAH-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif twTACATAvw Original Motif Original Motif HHCAMAMACAHRBAMAMAD HHTACATAVD HHYACATACAHRBAMAMAD Direction: Forward Position #: 1 Overlap #: 10 Alignment: HHCAMAMACAHRBAMAMAD HHTACATAVD--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RREB1 Original Motif Original Motif HHYACATACAHRBAMAMAD CCCCMAAMCAMCCMCMMMCV MCYMMAWACAMMHMCMMMBV Direction: Forward Position #: 1 Overlap #: 19 Alignment: HHYACATACAHRBAMAMAD- CCCCMAAMCAMCCMCMMMCV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Reverse Complement Reverse Complement BBYRYGYDRRTGTWTRRKGR DVTGCATGCATGBH BVTGCRTGSATGTHTRRKGR Direction: Forward Position #: 1 Overlap #: 14 Alignment: BBYRYGYDRRTGTWTRRKGR DVTGCATGCATGBH------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 3 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 3 wwTAAAwAww Reverse Complement Reverse Complement TYTATWT HHTWTTTADD THTATTTADD Direction: Forward Position #: 1 Overlap #: 7 Alignment: TYTATWT--- HHTWTTTADD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 1 Original Motif Reverse Complement THTATTTADD TTTWTTTT TTTWTTTWDD Direction: Forward Position #: 1 Overlap #: 8 Alignment: THTATTTADD TTTWTTTT-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif twTACATAvw Original Motif Reverse Complement TTTWTTTWDD DBTATGTAHH THTATKTAHH Direction: Forward Position #: 1 Overlap #: 10 Alignment: TTTWTTTWDD DBTATGTAHH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 5 Original Motif Reverse Complement THTATKTAHH TTTSTTTT TTTVTTTWHH Direction: Forward Position #: 1 Overlap #: 8 Alignment: THTATKTAHH TTTSTTTT-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Reverse Complement Original Motif HHWAAABAAA AAAAAAAAAAA DAAAAAAAAAA Direction: Forward Position #: 1 Overlap #: 10 Alignment: HHWAAABAAA- AAAAAAAAAAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif tyTCTkTkTCyy Original Motif Reverse Complement DAAAAAAAAAA VHGARAYAGAVV HHRAAAHARAAV Direction: Forward Position #: 1 Overlap #: 11 Alignment: DAAAAAAAAAA- VHGARAYAGAVV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwWAAAAAwa Original Motif Original Motif HHRAAAHARAAV WWAAAAAAWH DWAAAAAADAAV Direction: Forward Position #: 1 Overlap #: 10 Alignment: HHRAAAHARAAV WWAAAAAAWH-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif aaACAAAACaa Reverse Complement Reverse Complement BTTDTTTTTTWD TTGTTTTGTTT BTKTTTTKTTTD Direction: Forward Position #: 1 Overlap #: 11 Alignment: BTTDTTTTTTWD TTGTTTTGTTT- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 26 Combined Motif Reverse Complement Reverse Complement DAAAYAAAAYAV AAAAAAACAAARRA DAAAHAAAAYAAARRA Direction: Forward Position #: 3 Overlap #: 10 Alignment: DAAAYAAAAYAV---- --AAAAAAACAAARRA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACACACACACA Original Motif Original Motif DAAAHAAAAYAAARRA CACACACACACA HAMACAMAMMMAARRA Direction: Forward Position #: 1 Overlap #: 12 Alignment: DAAAHAAAAYAAARRA CACACACACACA---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 4 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 4 EWSR1-FLI1 Reverse Complement Original Motif GGAGGVMG GGAAGGAAGGAAGGAAGG GAAGGGRAGGAAGGGAAG Direction: Backward Position #: 6 Overlap #: 8 Alignment: -----GGAGGVMG----- GGAAGGAAGGAAGGAAGG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif SP1 Original Motif Reverse Complement GAAGGGRAGGAAGGGAAG GGGGGYGGGG GRRGGGGRGGAAGGGAAG Direction: Forward Position #: 1 Overlap #: 10 Alignment: GAAGGGRAGGAAGGGAAG GGGGGYGGGG-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rrAGGGGGArr Original Motif Original Motif GRRGGGGRGGAAGGGAAG VVAGGGGGAVV GRAGGGGGRGVAGGGAAG Direction: Forward Position #: 1 Overlap #: 11 Alignment: GRRGGGGRGGAAGGGAAG VVAGGGGGAVV------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGCCsCCrCCCss Original Motif Reverse Complement GRAGGGGGRGVAGGGAAG SSGGGCGGSGGCGSS GVRGGBGGRGGMGGGAAG Direction: Forward Position #: 1 Overlap #: 15 Alignment: GRAGGGGGRGVAGGGAAG SSGGGCGGSGGCGSS--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Klf4 Original Motif Original Motif GVRGGBGGRGGMGGGAAG DGGGYGKGGC DGGGBGKGGVGGMGGGAAG Direction: Forward Position #: 2 Overlap #: 9 Alignment: -GVRGGBGGRGGMGGGAAG DGGGYGKGGC--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 11 Combined Motif Original Motif Reverse Complement DGGGBGKGGVGGMGGGAAG GGCGGCGG DGGSBGCGGVGGMGGGAAG Direction: Forward Position #: 2 Overlap #: 8 Alignment: DGGGBGKGGVGGMGGGAAG -GGCGGCGG---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCrCYyYCGss Original Motif Reverse Complement DGGSBGCGGVGGMGGGAAG BBCGGKGGMGBB DGSGGGSGSGGVMGGGAAG Direction: Forward Position #: 1 Overlap #: 12 Alignment: DGGSBGCGGVGGMGGGAAG BBCGGKGGMGBB------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGsCTCss Combined Motif Original Motif Reverse Complement DGSGGGSGSGGVMGGGAAG BBGAGSCGVV DGSSBGAGSSGVVGGGAAG Direction: Forward Position #: 4 Overlap #: 10 Alignment: DGSGGGSGSGGVMGGGAAG ---BBGAGSCGVV------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif MZF1_5-13 Reverse Complement Reverse Complement CTTCCCVVCSSCTCBSSCH BTHCCCCTYB CTTCCCBTCSSCTCBSSCH Direction: Forward Position #: 1 Overlap #: 10 Alignment: CTTCCCVVCSSCTCBSSCH BTHCCCCTYB--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RREB1 Combined Motif Original Motif Original Motif CTTCCCBTCSSCTCBSSCH CCCCMAAMCAMCCMCMMMCV CTTCCCCHMVCCACCCSCHMMCV Direction: Forward Position #: 4 Overlap #: 16 Alignment: CTTCCCBTCSSCTCBSSCH---- ---CCCCMAAMCAMCCMCMMMCV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 5 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 5 AAAAAAAAAAA Original Motif Original Motif AAAASAAA AAAAAAAAAAA AAAAAMAAAAA Direction: Forward Position #: 2 Overlap #: 8 Alignment: -AAAASAAA-- AAAAAAAAAAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 1 Reverse Complement Reverse Complement TTTTTYTTTTT TTTWTTTT TTTTTTTTTTT Direction: Forward Position #: 1 Overlap #: 8 Alignment: TTTTTYTTTTT TTTWTTTT--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 26 Combined Motif Reverse Complement Reverse Complement AAAAAAAAAAA AAAAAAACAAARRA AAAAAAAAMAAARRA Direction: Forward Position #: 2 Overlap #: 10 Alignment: AAAAAAAAAAA---- -AAAAAAACAAARRA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwWAAAAAwa Original Motif Original Motif AAAAAAAAMAAARRA WWAAAAAAWH WAAAAAAAHAAARRA Direction: Forward Position #: 1 Overlap #: 10 Alignment: AAAAAAAAMAAARRA WWAAAAAAWH----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif aaACAAAACaa Original Motif Original Motif WAAAAAAAHAAARRA AAACAAAACAA AAAMAAAACAAARRA Direction: Forward Position #: 1 Overlap #: 11 Alignment: WAAAAAAAHAAARRA AAACAAAACAA---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif tyTCTkTkTCyy Original Motif Reverse Complement AAAMAAAACAAARRA VHGARAYAGAVV VHRAAAMARMHAARRA Direction: Forward Position #: 2 Overlap #: 11 Alignment: -AAAMAAAACAAARRA VHGARAYAGAVV---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- aaCAAAAACaa Combined Motif Original Motif Original Motif VHRAAAMARMHAARRA HHCAAAAACAH VHRAVMAAAAACAARA Direction: Forward Position #: 4 Overlap #: 11 Alignment: VHRAAAMARMHAARRA ---HHCAAAAACAH-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 2 Original Motif Original Motif VHRAVMAAAAACAARA CACACACA HASAMAMAAAACAARA Direction: Forward Position #: 1 Overlap #: 8 Alignment: VHRAVMAAAAACAARA CACACACA-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtATTTTTAww Original Motif Reverse Complement HASAMAMAAAACAARA DDTAAAAATHD HAYAAAAAWAACAARA Direction: Forward Position #: 1 Overlap #: 11 Alignment: HASAMAMAAAACAARA DDTAAAAATHD----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 27 Original Motif Original Motif HAYAAAAAWAACAARA CAYACACACACACA CAYACAMAMAYAMAAARA Direction: Forward Position #: 3 Overlap #: 12 Alignment: --HAYAAAAAWAACAARA CAYACACACACACA---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 6 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 6 Klf4 Original Motif Reverse Complement CCCCRCCC GCCYCMCCCD DCCCCACCCG Direction: Backward Position #: 2 Overlap #: 8 Alignment: -CCCCRCCC- GCCYCMCCCD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccCCmCACCcc Reverse Complement Reverse Complement CGGGTGGGGD DDGGTGRGGBD BGGGTGGGGDD Direction: Forward Position #: 1 Overlap #: 10 Alignment: CGGGTGGGGD- DDGGTGRGGBD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 23 Original Motif Reverse Complement BGGGTGGGGDD GGGGMGGG GGGGHGGGGDD Direction: Forward Position #: 1 Overlap #: 8 Alignment: BGGGTGGGGDD GGGGMGGG--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif SP1 Original Motif Reverse Complement GGGGHGGGGDD GGGGGYGGGG GGGGBGGGGGD Direction: Forward Position #: 1 Overlap #: 10 Alignment: GGGGHGGGGDD GGGGGYGGGG- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Reverse Complement Original Motif HCCCCCBCCCC SSCGCCSCCGCCCSS HCCCSCCCCCVCCCSS Direction: Forward Position #: 2 Overlap #: 10 Alignment: HCCCCCBCCCC----- -SSCGCCSCCGCCCSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 11 Reverse Complement Reverse Complement SSGGGVGGGGGSGGGD GGCGGCGG GGSGGCGGGGGSGGGD Direction: Forward Position #: 1 Overlap #: 8 Alignment: SSGGGVGGGGGSGGGD GGCGGCGG-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGMsGRGCGss Reverse Complement Reverse Complement HCCCSCCCCCGCCSCC BBCGCCCSGCVV VBCSCCCCSCSCCSCC Direction: Forward Position #: 1 Overlap #: 12 Alignment: HCCCSCCCCCGCCSCC BBCGCCCSGCVV---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif INSM1 Original Motif Reverse Complement VBCSCCCCSCSCCSCC MGCCCCCTGMCA MBCCCCCHSVCRCCSCC Direction: Forward Position #: 2 Overlap #: 11 Alignment: -VBCSCCCCSCSCCSCC MGCCCCCTGMCA----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 14 Reverse Complement Reverse Complement GGSGGKGVSHGGGGGBR GKGTGKGC GKGKGKGCSHGGGGGBR Direction: Forward Position #: 1 Overlap #: 8 Alignment: GGSGGKGVSHGGGGGBR GKGTGKGC--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCrCYyYCGss Reverse Complement Original Motif MBCCCCCHSGCRCRCYC BBCRCCYCCGBB VBCSCCCYCGCVCRCYC Direction: Forward Position #: 1 Overlap #: 12 Alignment: MBCCCCCHSGCRCRCYC BBCRCCYCCGBB----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 7 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 7 tyTCTkTkTCyy Reverse Complement Original Motif TTCTSTST BBTCTKTKTCHB CHBTTCTSTBTB Direction: Backward Position #: 4 Overlap #: 8 Alignment: -TTCTSTST--- BBTCTKTKTCHB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif aaACAAAACaa Original Motif Reverse Complement CHBTTCTSTBTB TTGTTTTGTTT CYGTTYTGTBTB Direction: Forward Position #: 1 Overlap #: 11 Alignment: CHBTTCTSTBTB TTGTTTTGTTT- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rmACAGCAGsr Original Motif Reverse Complement CYGTTYTGTBTB DVCTGCTGTVB BHSTKCTGTBTB Direction: Forward Position #: 1 Overlap #: 11 Alignment: CYGTTYTGTBTB DVCTGCTGTVB- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACACACACACA Original Motif Reverse Complement BHSTKCTGTBTB TGTGTGTGTGTG TBYKTSTGTGTB Direction: Forward Position #: 1 Overlap #: 12 Alignment: BHSTKCTGTBTB TGTGTGTGTGTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACACACACACA Original Motif Reverse Complement TBYKTSTGTGTB TGTGTGTGTGTG TGTGTGTGTGTG Direction: Forward Position #: 1 Overlap #: 12 Alignment: TBYKTSTGTGTB TGTGTGTGTGTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Original Motif Reverse Complement TGTGTGTGTGTG TTTTTTTTTTT TKTKTKTKTKTG Direction: Forward Position #: 1 Overlap #: 11 Alignment: TGTGTGTGTGTG TTTTTTTTTTT- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 26 Combined Motif Original Motif Original Motif TKTKTKTKTKTG TKKTTTGTTTTTTT TKTKTTTTTDTKTTTT Direction: Forward Position #: 3 Overlap #: 10 Alignment: TKTKTKTKTKTG---- --TKKTTTGTTTTTTT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 27 Original Motif Reverse Complement TKTKTTTTTDTKTTTT TGTGTGTGTGTKTG TGTGTKTKTGTKTKTT Direction: Forward Position #: 1 Overlap #: 14 Alignment: TKTKTTTTTDTKTTTT TGTGTGTGTGTKTG-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 25 Original Motif Reverse Complement TGTGTKTKTGTKTKTT TGTGTGKVTGTGTG TGTGTGTBTGTGTGTT Direction: Forward Position #: 1 Overlap #: 14 Alignment: TGTGTKTKTGTKTKTT TGTGTGKVTGTGTG-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 8 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 8 wtTTWwAAAaw Original Motif Reverse Complement TTTWWAAW DDTTTWAAAHH HTTTWWAAWDD Direction: Backward Position #: 2 Overlap #: 8 Alignment: --TTTWWAAW- DDTTTWAAAHH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtATTTTTAww Original Motif Reverse Complement HTTTWWAAWDD DDTAAAAATHD HTTWAAAATHD Direction: Forward Position #: 1 Overlap #: 11 Alignment: HTTTWWAAWDD DDTAAAAATHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTAAwAAww Original Motif Original Motif HTTWAAAATHD DDTAAWAAHH DWTAAWAATHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: HTTWAAAATHD DDTAAWAAHH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwWAAAAAwa Original Motif Original Motif DWTAAWAATHD WWAAAAAAWH DWWAAAAAWHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DWTAAWAATHD WWAAAAAAWH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTAAAwAww Original Motif Original Motif DWWAAAAAWHD DDTAAAWAHH DDTAAAAAHHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DWWAAAAAWHD DDTAAAWAHH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wyATTTTAww Original Motif Reverse Complement DDTAAAAAHHD DDTAAAATHD DDTAAAAWHHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DDTAAAAAHHD DDTAAAATHD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif aaCAAAAACaa Original Motif Original Motif DDTAAAAWHHD HHCAAAAACAH HDYAAAAACHD Direction: Forward Position #: 1 Overlap #: 11 Alignment: DDTAAAAWHHD HHCAAAAACAH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Reverse Complement Reverse Complement DHGTTTTTKDH TTTTTTTTTTT TTKTTTTTTTT Direction: Forward Position #: 1 Overlap #: 11 Alignment: DHGTTTTTKDH TTTTTTTTTTT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 1 Original Motif Reverse Complement TTKTTTTTTTT TTTWTTTT TTTTTTTTTTT Direction: Forward Position #: 1 Overlap #: 8 Alignment: TTKTTTTTTTT TTTWTTTT--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTAATTAATTAww Original Motif Reverse Complement TTTTTTTTTTT DHTAATTAATTADH WTTWWTTWWTTADH Direction: Forward Position #: 1 Overlap #: 11 Alignment: TTTTTTTTTTT--- DHTAATTAATTADH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 9 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 9 ssCwGGCCwGCss Original Motif Reverse Complement GCTGGGAW BBGCTGGCCWGBB BBGCTGGSMWGBB Direction: Forward Position #: 3 Overlap #: 8 Alignment: --GCTGGGAW--- BBGCTGGCCWGBB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 12 Combined Motif Reverse Complement Reverse Complement BBCWYSCCAGCBB GCTGRCCT BGCTGSCCWGCBB Direction: Forward Position #: 2 Overlap #: 8 Alignment: BBCWYSCCAGCBB -GCTGRCCT---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccCCmCACCcc Reverse Complement Reverse Complement BBGCWGGSCAGCB DDGGTGRGGBD BDGSTGGGGDGCB Direction: Forward Position #: 1 Overlap #: 11 Alignment: BBGCWGGSCAGCB DDGGTGRGGBD-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif sgCTGGCCAGcs Reverse Complement Original Motif BGCDCCCCASCHB BBCTGGCCAGVV BGCTSSCCAGCVB Direction: Forward Position #: 1 Overlap #: 12 Alignment: BGCDCCCCASCHB BBCTGGCCAGVV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGCTswGCCms Reverse Complement Original Motif BVGCTGGSSAGCB VBGCTSAGCCHB BBGCTGRGCMGBB Direction: Forward Position #: 1 Overlap #: 12 Alignment: BVGCTGGSSAGCB VBGCTSAGCCHB- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- INSM1 Combined Motif Reverse Complement Reverse Complement BBCRGCMCAGCBB MGCCCCCTGMCA BBCRGCMCAGCCCCCTGMCA Direction: Forward Position #: 9 Overlap #: 5 Alignment: BBCRGCMCAGCBB------- --------MGCCCCCTGMCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rrAGGGGGArr Combined Motif Reverse Complement Original Motif TGYCAGGGGGCTGRGCMGBB VVAGGGGGAVV TGBVAGGGGGMBGRGCMGBB Direction: Forward Position #: 3 Overlap #: 11 Alignment: TGYCAGGGGGCTGRGCMGBB --VVAGGGGGAVV------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- EWSR1-FLI1 Combined Motif Reverse Complement Reverse Complement BBCRGCMCVYCCCCCTVVCA CCTTCCTTCCTTCCTTCC BBCRGCMCVCCYYCCTTCCWTCCTTCC Direction: Forward Position #: 10 Overlap #: 11 Alignment: BBCRGCMCVYCCCCCTVVCA------- ---------CCTTCCTTCCTTCCTTCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGCksCGss Original Motif Original Motif BBCRGCMCVCCYYCCTTCCWTCCTTCC VVCGCKSCGBB BBCGSBSCGCCYYCCTTCCWTCCTTCC Direction: Forward Position #: 1 Overlap #: 11 Alignment: BBCRGCMCVCCYYCCTTCCWTCCTTCC VVCGCKSCGBB---------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGMsGRGCGss Original Motif Reverse Complement BBCGSBSCGCCYYCCTTCCWTCCTTCC BBCGCCCSGCVV BBCGCCCCGCVBYCCTTCCWTCCTTCC Direction: Forward Position #: 1 Overlap #: 12 Alignment: BBCGSBSCGCCYYCCTTCCWTCCTTCC BBCGCCCSGCVV--------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 10 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 10 twTACATAvw Original Motif Original Motif TAMATA HHTACATAVD HHTACATAVD Direction: Forward Position #: 3 Overlap #: 6 Alignment: --TAMATA-- HHTACATAVD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTAAAwAww Original Motif Original Motif HHTACATAVD DDTAAAWAHH HHTAMATAHH Direction: Forward Position #: 1 Overlap #: 10 Alignment: HHTACATAVD DDTAAAWAHH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtATTTTTAww Original Motif Reverse Complement HHTAMATAHH DDTAAAAATHD DDTAAAWATHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: HHTAMATAHH- DDTAAAAATHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wrTGTATACAyw Original Motif Original Motif DDTAAAWATHD HDTGTATACAHD HDTRWATAYAHD Direction: Forward Position #: 1 Overlap #: 11 Alignment: DDTAAAWATHD- HDTGTATACAHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTAATTAATTAww Original Motif Original Motif HDTRWATAYAHD HDTAATTAATTAHD HDTAAWTAHWTAHD Direction: Forward Position #: 1 Overlap #: 12 Alignment: HDTRWATAYAHD-- HDTAATTAATTAHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 2 Combined Motif Original Motif Reverse Complement HDTAAWTAHWTAHD TGTGTGTG AWTAHWTAHDTGTRHDTAAWTAHW Direction: Backward Position #: 11 Overlap #: 4 Alignment: ----HDTAAWTAHWTAHD ----------TGTGTGTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 11 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 11 sssCGssGCsss Original Motif Original Motif CCGCCGCC SSSCGSSGCSSS SSCCGCSGCCSS Direction: Backward Position #: 3 Overlap #: 8 Alignment: --CCGCCGCC-- SSSCGSSGCSSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Reverse Complement Reverse Complement SSGGCSGCGGSS SSGGGCGGSGGCGSS SSGGSGGCGGSGGCGSS Direction: Forward Position #: 3 Overlap #: 10 Alignment: SSGGCSGCGGSS----- --SSGGGCGGSGGCGSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 6 Reverse Complement Original Motif SSCGCCSCCGCCSCCSS CCCCRCCC CCCCRCCCCCGCCSCCSS Direction: Forward Position #: 2 Overlap #: 7 Alignment: -SSCGCCSCCGCCSCCSS CCCCRCCC---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCrCYyYCGss Reverse Complement Reverse Complement SSGGSGGCGGGGGMGGGG BBCGGKGGMGBB SSCGSGGSSGGGGMGGGG Direction: Forward Position #: 1 Overlap #: 12 Alignment: SSGGSGGCGGGGGMGGGG BBCGGKGGMGBB------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCksCGss Combined Motif Original Motif Reverse Complement SSCGSGGSSGGGGMGGGG BBCGSRGCGVV SSCGSSGSVGCGGVGGGG Direction: Forward Position #: 4 Overlap #: 11 Alignment: SSCGSGGSSGGGGMGGGG ---BBCGSRGCGVV---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Zfx Original Motif Original Motif SSCGSSGSVGCGGVGGGG BBVGCCBVGGCCTV SBSGSCGSGGCSKVGGGG Direction: Forward Position #: 1 Overlap #: 14 Alignment: SSCGSSGSVGCGGVGGGG BBVGCCBVGGCCTV---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 4 Combined Motif Reverse Complement Original Motif CCCCVRSGCCSCGSCSBS CYBCCTCC CCCCBCCKCCSCGSCSBS Direction: Forward Position #: 3 Overlap #: 8 Alignment: CCCCVRSGCCSCGSCSBS --CYBCCTCC-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Klf4 Original Motif Reverse Complement CCCCBCCKCCSCGSCSBS GCCYCMCCCD SCCYCMCCCHSCGSCSBS Direction: Forward Position #: 1 Overlap #: 10 Alignment: CCCCBCCKCCSCGSCSBS GCCYCMCCCD-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif SP1 Original Motif Original Motif SCCYCMCCCHSCGSCSBS CCCCKCCCCC CCCCBCCCCCSCGSCSBS Direction: Forward Position #: 1 Overlap #: 10 Alignment: SCCYCMCCCHSCGSCSBS CCCCKCCCCC-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif INSM1 Original Motif Reverse Complement CCCCBCCCCCSCGSCSBS MGCCCCCTGMCA MSCCCCCYBMCRCGSCSBS Direction: Forward Position #: 2 Overlap #: 11 Alignment: -CCCCBCCCCCSCGSCSBS MGCCCCCTGMCA------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 12 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 12 ssCwGGCCwGCss Original Motif Original Motif AGGMCAGC BBCWGGCCAGCBB BBCAGGCCAGCBB Direction: Forward Position #: 4 Overlap #: 8 Alignment: ---AGGMCAGC-- BBCWGGCCAGCBB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR1H2RXRA Combined Motif Reverse Complement Reverse Complement BBGCTGGCCTGBB GTTGACCTTTGACCTTT BBGYTGRCCTKTGACCTTT Direction: Forward Position #: 3 Overlap #: 11 Alignment: BBGCTGGCCTGBB------ --GTTGACCTTTGACCTTT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Original Motif Reverse Complement BBGYTGRCCTKTGACCTTT GGYGCTGTCCATGGTGCTGAA GVHGCTGWCCWKKGWSCTKWA Direction: Forward Position #: 2 Overlap #: 19 Alignment: -BBGYTGRCCTKTGACCTTT- GGYGCTGTCCATGGTGCTGAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- sgCTGGCCAGcs Combined Motif Original Motif Reverse Complement GVHGCTGWCCWKKGWSCTKWA VVCTGGCCAGBB GVHGCTGGCCAGBGWSCTKWA Direction: Forward Position #: 3 Overlap #: 12 Alignment: GVHGCTGWCCWKKGWSCTKWA --VVCTGGCCAGBB------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Original Motif Reverse Complement GVHGCTGGCCAGBGWSCTKWA MGGTCAGGGTGACCTRDBHV GVHGCKGKCMDGBKDVCYKDDBHV Direction: Forward Position #: 5 Overlap #: 17 Alignment: GVHGCTGGCCAGBGWSCTKWA--- ----MGGTCAGGGTGACCTRDBHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- mkARGCCACG Combined Motif Original Motif Original Motif GVHGCKGKCMDGBKDVCYKDDBHV CKAGGCCACG GVHKAGGBCAHGBKDVCYKDDBHV Direction: Forward Position #: 3 Overlap #: 10 Alignment: GVHGCKGKCMDGBKDVCYKDDBHV --CKAGGCCACG------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Reverse Complement Reverse Complement VDBHDRMGBHRBCDTGBCCTYDVC BAGGYCABHBTGACCKHV VDBHBAVGBCABCBTGDCCTHVVC Direction: Forward Position #: 5 Overlap #: 18 Alignment: VDBHDRMGBHRBCDTGBCCTYDVC ----BAGGYCABHBTGACCKHV-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 13 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 13 tyTCTkTkTCyy Original Motif Reverse Complement GAGRCAGR VHGARAYAGAVV VHGAGACAGAVV Direction: Forward Position #: 3 Overlap #: 8 Alignment: --GAGRCAGR-- VHGARAYAGAVV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGsCTCss Original Motif Reverse Complement VHGAGACAGAVV BBGAGSCGVV VVGAGRCRGRVV Direction: Forward Position #: 1 Overlap #: 10 Alignment: VHGAGACAGAVV BBGAGSCGVV-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 14 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 14 Motif 27 Original Motif Original Motif GCRCACRC CAYACACACACACA CAYRCACACACACA Direction: Forward Position #: 4 Overlap #: 8 Alignment: ---GCRCACRC--- CAYACACACACACA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACACACACACA Reverse Complement Reverse Complement TGTGTGTGTGMKTG TGTGTGTGTGTG TGTGTGTGTGHGTG Direction: Forward Position #: 1 Overlap #: 12 Alignment: TGTGTGTGTGMKTG TGTGTGTGTGTG-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACACACACACA Original Motif Reverse Complement TGTGTGTGTGHGTG TGTGTGTGTGTG TGTGTGTGTGTGTG Direction: Forward Position #: 1 Overlap #: 12 Alignment: TGTGTGTGTGHGTG TGTGTGTGTGTG-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Klf4 Original Motif Original Motif TGTGTGTGTGTGTG DGGGYGKGGC TGKGTGTGKSTGTG Direction: Forward Position #: 1 Overlap #: 10 Alignment: TGTGTGTGTGTGTG DGGGYGKGGC---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 25 Original Motif Reverse Complement TGKGTGTGKSTGTG TGTGTGKVTGTGTG TGTGTGTGTGTGTG Direction: Forward Position #: 1 Overlap #: 14 Alignment: TGKGTGTGKSTGTG TGTGTGKVTGTGTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Egr1 Combined Motif Original Motif Original Motif TGTGTGTGTGTGTG HGCGTGGGCGK TGTGYGTGKGYGTG Direction: Forward Position #: 3 Overlap #: 11 Alignment: TGTGTGTGTGTGTG --HGCGTGGGCGK- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 6 Reverse Complement Original Motif CACMCYCACKCACA CCCCRCCC CCMCVCCCACKCACA Direction: Forward Position #: 2 Overlap #: 7 Alignment: -CACMCYCACKCACA CCCCRCCC------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ccCCmCACCcc Combined Motif Reverse Complement Reverse Complement TGTGYGTGGGBGRGG DDGGTGRGGBD TGDGGGTGGGGGVGG Direction: Forward Position #: 3 Overlap #: 11 Alignment: TGTGYGTGGGBGRGG --DDGGTGRGGBD-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- yrTGTGCACAyr Combined Motif Reverse Complement Original Motif CCVCCCCCACCCDCA BVTGTGCACABV CCVYSYSCACVCVCA Direction: Forward Position #: 2 Overlap #: 12 Alignment: CCVCCCCCACCCDCA -BVTGTGCACABV-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGrGCGss Reverse Complement Original Motif TGBGBGTGSKSMBGG VSCGRGCGBV BGCGDGYGSKSMBGG Direction: Forward Position #: 1 Overlap #: 10 Alignment: TGBGBGTGSKSMBGG VSCGRGCGBV----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 15 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 15 wyATTTTAww Reverse Complement Original Motif CATTTKC DHATTTTADD DMATTTTMDD Direction: Forward Position #: 2 Overlap #: 7 Alignment: -CATTTKC-- DHATTTTADD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtATTTTTAww Original Motif Original Motif DMATTTTMDD DHATTTTTADD DHATTTTHADD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DMATTTTMDD- DHATTTTTADD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif dwCTTTTCwy Original Motif Original Motif DHATTTTHADD DHCTTTTCHH DHMTTTTCHHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DHATTTTHADD DHCTTTTCHH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwWAAAAAwa Reverse Complement Original Motif DHHGAAAAYHD WWAAAAAAWH DHWRAAAAYHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DHHGAAAAYHD WWAAAAAAWH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ryayAyAyrtGTRTrTry Combined Motif Original Motif Reverse Complement DHWRAAAAYHD HDAMACACAKKTKTKTHD DHDAAAMACADKTKTKTHD Direction: Forward Position #: 2 Overlap #: 10 Alignment: DHWRAAAAYHD-------- -HDAMACACAKKTKTKTHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtTTWwAAAaw Original Motif Original Motif DHDAAAMACADKTKTKTHD HHTTTWAAADD DHTWWAAAAHDKTKTKTHD Direction: Forward Position #: 1 Overlap #: 11 Alignment: DHDAAAMACADKTKTKTHD HHTTTWAAADD-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Original Motif Reverse Complement DHTWWAAAAHDKTKTKTHD TGRCCTKTGHCCKAB DHTWWAAAAWDDYSTKTVBCCKAB Direction: Forward Position #: 10 Overlap #: 10 Alignment: DHTWWAAAAHDKTKTKTHD----- ---------TGRCCTKTGHCCKAB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif tyTCTkTkTCyy Reverse Complement Reverse Complement BTRGGVVARASMHHWTTTTWWAHD VHGARAYAGAVV VHGRRAHAGAVMHHWTTTTWWAHD Direction: Forward Position #: 1 Overlap #: 12 Alignment: BTRGGVVARASMHHWTTTTWWAHD VHGARAYAGAVV------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NR2F1 Reverse Complement Reverse Complement DHTWWAAAAWDDYVTCTDTMKCHV AKGYYCAAAGRTCA VDKHHMAAAGRTCATCTDTMKCHV Direction: Forward Position #: 1 Overlap #: 14 Alignment: DHTWWAAAAWDDYVTCTDTMKCHV AKGYYCAAAGRTCA---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yrTGTGCACAyr Reverse Complement Original Motif VHGRRAHAGATGAMCTTTYHHYDB BVTGTGCACABV BHKGKRCASABDAMCTTTYHHYDB Direction: Forward Position #: 1 Overlap #: 12 Alignment: VHGRRAHAGATGAMCTTTYHHYDB BVTGTGCACABV------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 16 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 16 RXRAVDR Original Motif Original Motif CTGDGTTC GGGTCAWBGRGTTCA ACTGRGTTCGGGTCA Direction: Backward Position #: 2 Overlap #: 8 Alignment: ------CTGDGTTC- GGGTCAWBGRGTTCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif EWSR1-FLI1 Original Motif Original Motif ACTGRGTTCGGGTCA GGAAGGAAGGAAGGAAGG GGAAGGAAGGAAGGAMKGRGTTCGGGTCA Direction: Forward Position #: 15 Overlap #: 4 Alignment: --------------ACTGRGTTCGGGTCA GGAAGGAAGGAAGGAAGG----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NR2F1 Reverse Complement Original Motif TGACCCGAACKCYYTCCTTCCTTCCTTCC TGAMCTTTGMMCYT TGACCYKWRCDCYTTCCTTCCTTCCTTCC Direction: Forward Position #: 1 Overlap #: 14 Alignment: TGACCCGAACKCYYTCCTTCCTTCCTTCC TGAMCTTTGMMCYT--------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Reverse Complement Reverse Complement GGAAGGAAGGAAGGAAKGDGKWYKGGTCA VRVDGGHACAVDDKGTHCTDWH GGAAGGAAGGAAGGAAKGDGKHBGGDWCAVDDKGTHCTDWH Direction: Forward Position #: 20 Overlap #: 10 Alignment: GGAAGGAAGGAAGGAAKGDGKWYKGGTCA------------ -------------------VRVDGGHACAVDDKGTHCTDWH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssGCTswGCCms Combined Motif Reverse Complement Reverse Complement HWDAGHACRHHVTGWHCCVHYCDCYTTCCTTCCTTCCTTCC BDGGCTSAGCBV HDDRGCWCAGCVBGWHCCVHYCDCYTTCCTTCCTTCCTTCC Direction: Forward Position #: 2 Overlap #: 12 Alignment: HWDAGHACRHHVTGWHCCVHYCDCYTTCCTTCCTTCCTTCC -BDGGCTSAGCBV---------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- REST Combined Motif Original Motif Original Motif HDDRGCWCAGCVBGWHCCVHYCDCYTTCCTTCCTTCCTTCC TTCAGCACCATGGACAGCKCC HDDDSMRCACCVTGRACMGHHCHCYTTCCTTCCTTCCTTCC Direction: Forward Position #: 3 Overlap #: 21 Alignment: HDDRGCWCAGCVBGWHCCVHYCDCYTTCCTTCCTTCCTTCC --TTCAGCACCATGGACAGCKCC------------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- tyTCTkTkTCyy Combined Motif Original Motif Reverse Complement HDDDSMRCACCVTGRACMGHHCHCYTTCCTTCCTTCCTTCC VHGARAYAGAVV HHHGAAACAGMVHGRACMGHHCHCYTTCCTTCCTTCCTTCC Direction: Forward Position #: 2 Overlap #: 12 Alignment: HDDDSMRCACCVTGRACMGHHCHCYTTCCTTCCTTCCTTCC -VHGARAYAGAVV---------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rmACAGCAGsr Combined Motif Original Motif Original Motif HHHGAAACAGMVHGRACMGHHCHCYTTCCTTCCTTCCTTCC VVACAGCAGVD HHHRCARCAGVVHGRACMGHHCHCYTTCCTTCCTTCCTTCC Direction: Forward Position #: 2 Overlap #: 11 Alignment: HHHGAAACAGMVHGRACMGHHCHCYTTCCTTCCTTCCTTCC -VVACAGCAGVD----------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 17 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 17 EWSR1-FLI1 Original Motif Original Motif RGGAAR GGAAGGAAGGAAGGAAGG GGAAGGAAGGAAGGAAGG Direction: Forward Position #: 12 Overlap #: 6 Alignment: -----------RGGAAR- GGAAGGAAGGAAGGAAGG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rrAGGGGGArr Combined Motif Original Motif Original Motif GGAAGGAAGGAAGGAAGG VVAGGGGGAVV GGAAGGRRGRARGGAAGG Direction: Forward Position #: 2 Overlap #: 11 Alignment: GGAAGGAAGGAAGGAAGG -VVAGGGGGAVV------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- dwCTTTTCwy Combined Motif Reverse Complement Original Motif CCTTCCKTKCMMCCTTCC DHCTTTTCHH CCTTCYTTTCHMCCTTCC Direction: Forward Position #: 3 Overlap #: 10 Alignment: CCTTCCKTKCMMCCTTCC --DHCTTTTCHH------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- MIZF Combined Motif Original Motif Original Motif CCTTCYTTTCHMCCTTCC BAACGTCCGC CCTTCYTTTCHAMCKTCCGC Direction: Forward Position #: 11 Overlap #: 8 Alignment: CCTTCYTTTCHMCCTTCC-- ----------BAACGTCCGC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 4 Reverse Complement Reverse Complement GCGGARGYTDGAAAKGAAGG GGAGGVMG GGMGGAAGYTDGAAAKGAAGG Direction: Forward Position #: 2 Overlap #: 7 Alignment: -GCGGARGYTDGAAAKGAAGG GGAGGVMG------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- MZF1_5-13 Combined Motif Reverse Complement Reverse Complement CCTTCYTTTCHAMCTTCCYCC BTHCCCCTYB CHTHCCYYTCBAMCTTCCYCC Direction: Forward Position #: 2 Overlap #: 10 Alignment: CCTTCYTTTCHAMCTTCCYCC -BTHCCCCTYB---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NFKB1 Combined Motif Reverse Complement Reverse Complement GGMGGAAGYTBGAMKGGHADG GGGGAAKCCCC GGMGGAAGYTBGARGGGMAKSCCC Direction: Forward Position #: 14 Overlap #: 8 Alignment: GGMGGAAGYTBGAMKGGHADG--- -------------GGGGAAKCCCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 13 Combined Motif Original Motif Original Motif GGMGGAAGYTBGARGGGMAKSCCC GAGRCAGR GGAGGCAGBTBGARGGGMAKSCCC Direction: Forward Position #: 2 Overlap #: 8 Alignment: GGMGGAAGYTBGARGGGMAKSCCC -GAGRCAGR--------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif tyTCTkTkTCyy Original Motif Reverse Complement GGAGGCAGBTBGARGGGMAKSCCC VHGARAYAGAVV VGGAGRCAGAHVGARGGGMAKSCCC Direction: Forward Position #: 2 Overlap #: 11 Alignment: -GGAGGCAGBTBGARGGGMAKSCCC VHGARAYAGAVV------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccCCmCACCcc Original Motif Reverse Complement VGGAGRCAGAHVGARGGGMAKSCCC DDGGTGRGGBD VGGRKGVRGDHVGARGGGMAKSCCC Direction: Forward Position #: 1 Overlap #: 11 Alignment: VGGAGRCAGAHVGARGGGMAKSCCC DDGGTGRGGBD-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 18 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 18 Motif 2 Original Motif Original Motif AMACA CACACACA AMACACAC Direction: Backward Position #: 1 Overlap #: 5 Alignment: ---AMACA CACACACA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACACACACACA Original Motif Original Motif AMACACAC CACACACACACA CACACACACACA Direction: Forward Position #: 2 Overlap #: 8 Alignment: -AMACACAC--- CACACACACACA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 27 Reverse Complement Reverse Complement TGTGTGTGTGTG TGTGTGTGTGTKTG TGTGTGTGTGTGTG Direction: Forward Position #: 1 Overlap #: 12 Alignment: TGTGTGTGTGTG-- TGTGTGTGTGTKTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACACACACACA Original Motif Reverse Complement TGTGTGTGTGTGTG TGTGTGTGTGTG TGTGTGTGTGTGTG Direction: Forward Position #: 1 Overlap #: 12 Alignment: TGTGTGTGTGTGTG TGTGTGTGTGTG-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 25 Original Motif Reverse Complement TGTGTGTGTGTGTG TGTGTGKVTGTGTG TGTGTGTGTGTGTG Direction: Forward Position #: 1 Overlap #: 14 Alignment: TGTGTGTGTGTGTG TGTGTGKVTGTGTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- aaACAAAACaa Combined Motif Original Motif Reverse Complement TGTGTGTGTGTGTG TTGTTTTGTTT TGTGTGTBKKTKTGTTT Direction: Forward Position #: 7 Overlap #: 8 Alignment: TGTGTGTGTGTGTG--- ------TTGTTTTGTTT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif aaCAAAAACaa Reverse Complement Original Motif AAACARARYBACACACA HHCAAAAACAH AAMMAAAACHACACACA Direction: Forward Position #: 1 Overlap #: 11 Alignment: AAACARARYBACACACA HHCAAAAACAH------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ryayAyAyrtGTRTrTry Reverse Complement Original Motif TGTGTGTHGTTTTYRTT DHAYAYAYRTGTGTRTDH DHAYAYAYRTGTGTGTDKTTTTYRTT Direction: Forward Position #: 10 Overlap #: 9 Alignment: ---------TGTGTGTHGTTTTYRTT DHAYAYAYRTGTGTRTDH-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wrTGTATACAyw Original Motif Original Motif DHAYAYAYRTGTGTGTDKTTTTYRTT HDTGTATACAHD HDTRTAYACATDTGTGTDKTTTTYRTT Direction: Forward Position #: 2 Overlap #: 11 Alignment: -DHAYAYAYRTGTGTGTDKTTTTYRTT HDTGTATACAHD--------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 5 Reverse Complement Original Motif AAMMAAAAYDACACAHATGTMTAMADH AAAASAAA AAAAMAAAYDACACAHATGTMTAMADH Direction: Forward Position #: 1 Overlap #: 8 Alignment: AAMMAAAAYDACACAHATGTMTAMADH AAAASAAA------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 19 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 19 Motif 13 Reverse Complement Reverse Complement CCWGSCT MCTGKCTC CCTGBCTC Direction: Forward Position #: 1 Overlap #: 7 Alignment: CCWGSCT- MCTGKCTC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif EWSR1-FLI1 Original Motif Reverse Complement CCTGBCTC CCTTCCTTCCTTCCTTCC CCTKCCTYCCTTCCTTCC Direction: Forward Position #: 1 Overlap #: 8 Alignment: CCTGBCTC---------- CCTTCCTTCCTTCCTTCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCwGGCCwGCss Combined Motif Reverse Complement Reverse Complement GGAAGGAAGGKAGGYAGG BBGCTGGCCWGBB GGAAGGAAGGKAGGCWGGCCWGBB Direction: Forward Position #: 12 Overlap #: 7 Alignment: GGAAGGAAGGKAGGYAGG------ -----------BBGCTGGCCWGBB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- INSM1 Combined Motif Reverse Complement Reverse Complement BBCWGGCCWGCCTYCCTTCCTTCC MGCCCCCTGMCA BHSYSSCCWGMCWYCCTTCCTTCC Direction: Forward Position #: 2 Overlap #: 12 Alignment: BBCWGGCCWGCCTYCCTTCCTTCC -MGCCCCCTGMCA----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGsCTCss Original Motif Original Motif BHSYSSCCWGMCWYCCTTCCTTCC VVCGSCTCBB BVCBSCYCDGMCWYCCTTCCTTCC Direction: Forward Position #: 1 Overlap #: 10 Alignment: BHSYSSCCWGMCWYCCTTCCTTCC VVCGSCTCBB-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGsCwsCss Original Motif Original Motif BVCBSCYCDGMCWYCCTTCCTTCC BBCGSCWSCBB BVCGSCTCCBVCWYCCTTCCTTCC Direction: Forward Position #: 1 Overlap #: 11 Alignment: BVCBSCYCDGMCWYCCTTCCTTCC BBCGSCWSCBB------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Tcfcp2l1 Original Motif Original Motif BVCGSCTCCBVCWYCCTTCCTTCC CCAGYYHVADCCRG CCVGBCHVHDCCDSCCTTCCTTCC Direction: Forward Position #: 1 Overlap #: 14 Alignment: BVCGSCTCCBVCWYCCTTCCTTCC CCAGYYHVADCCRG---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- REST Combined Motif Reverse Complement Reverse Complement GGAAGGAAGGSDGGHHVHGBCVGG GGYGCTGTCCATGGTGCTGAA GGAAGGAAGGSDGGHBCTGTCCVBGGTGCTGAA Direction: Forward Position #: 13 Overlap #: 12 Alignment: GGAAGGAAGGSDGGHHVHGBCVGG--------- ------------GGYGCTGTCCATGGTGCTGAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- SP1 Combined Motif Reverse Complement Original Motif TTCAGCACCBBGGACAGBDCCDSCCTTCCTTCC CCCCKCCCCC TTCAGCACCCBGSMCMSBDCCDSCCTTCCTTCC Direction: Forward Position #: 8 Overlap #: 10 Alignment: TTCAGCACCBBGGACAGBDCCDSCCTTCCTTCC -------CCCCKCCCCC---------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif sgCTGGCCAGcs Original Motif Reverse Complement TTCAGCACCCBGSMCMSBDCCDSCCTTCCTTCC VVCTGGCCAGBB BBCWGSMCMSBBSMCMSBDCCDSCCTTCCTTCC Direction: Forward Position #: 1 Overlap #: 12 Alignment: TTCAGCACCCBGSMCMSBDCCDSCCTTCCTTCC VVCTGGCCAGBB--------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 20 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 20 ssGCTswGCCms Original Motif Original Motif CTCTGY VBGCTSAGCCHB VBGCTCWGCCHB Direction: Forward Position #: 4 Overlap #: 6 Alignment: ---CTCTGY--- VBGCTSAGCCHB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 7 Combined Motif Original Motif Reverse Complement VBGCTCWGCCHB TTCTSTST VTKCTCTGYCHB Direction: Forward Position #: 2 Overlap #: 8 Alignment: VBGCTCWGCCHB -TTCTSTST--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NR1H2RXRA Reverse Complement Original Motif BDGMCAGAGRAV AAAGGTCAAAGGTCAAC AAAGGTCAACHDRRSWSBDGMC Direction: Backward Position #: 11 Overlap #: 7 Alignment: BDGMCAGAGRAV---------- -----AAAGGTCAAAGGTCAAC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 21 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 21 Motif 15 Original Motif Reverse Complement ATKTM CATTTKC CATTTBC Direction: Forward Position #: 2 Overlap #: 5 Alignment: -ATKTM- CATTTKC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 10 Original Motif Reverse Complement CATTTBC TATRTA YATDTAC Direction: Forward Position #: 1 Overlap #: 6 Alignment: CATTTBC TATRTA- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtATTTTTAww Original Motif Original Motif YATDTAC DHATTTTTADD DHATTTWYADD Direction: Forward Position #: 2 Overlap #: 7 Alignment: -YATDTAC--- DHATTTTTADD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wyATTTTAww Original Motif Original Motif DHATTTWYADD DHATTTTADD DHATTTTHADD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DHATTTWYADD DHATTTTADD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif tyTCTkTkTCyy Reverse Complement Reverse Complement DDTHAAAATHD VHGARAYAGAVV HHKAAAHAKAHV Direction: Forward Position #: 1 Overlap #: 11 Alignment: DDTHAAAATHD- VHGARAYAGAVV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif twTACATAvw Reverse Complement Reverse Complement BHTRTHTTTYHH DBTATGTAHH HBTATGTWHHHH Direction: Forward Position #: 1 Overlap #: 10 Alignment: BHTRTHTTTYHH DBTATGTAHH-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTAAAwAww Original Motif Reverse Complement HBTATGTWHHHH HHTWTTTADD HHTATTTAHHHH Direction: Forward Position #: 1 Overlap #: 10 Alignment: HBTATGTWHHHH HHTWTTTADD-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwWAAAAAwa Original Motif Reverse Complement HHTATTTAHHHH HWTTTTTTWW HHTWTTTWWHHH Direction: Forward Position #: 1 Overlap #: 10 Alignment: HHTATTTAHHHH HWTTTTTTWW-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Reverse Complement Original Motif HHHWWAAAWAHH HVCATGCATGCABD HVCATGCATGCAHDWAAAWAHH Direction: Forward Position #: 11 Overlap #: 4 Alignment: ----------HHHWWAAAWAHH HVCATGCATGCABD-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wrTGTATACAyw Reverse Complement Original Motif HHTWTTTWDHTGCATGCATGBH HDTGTATACAHD HDTKTWTAHATDCATGCATGBH Direction: Forward Position #: 1 Overlap #: 12 Alignment: HHTWTTTWDHTGCATGCATGBH HDTGTATACAHD---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 22 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 22 Motif 11 Original Motif Original Motif CMGCRGC CCGCCGCC CCCGCVGC Direction: Backward Position #: 2 Overlap #: 7 Alignment: CMGCRGC- CCGCCGCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rmACAGCAGsr Reverse Complement Reverse Complement GCBGCGGG DVCTGCTGTVB DGCTGCKGKVB Direction: Forward Position #: 2 Overlap #: 8 Alignment: -GCBGCGGG-- DVCTGCTGTVB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGCksCGss Original Motif Reverse Complement DGCTGCKGKVB BBCGSRGCGVV BGCKGCGSGVB Direction: Forward Position #: 1 Overlap #: 11 Alignment: DGCTGCKGKVB BBCGSRGCGVV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGsCwsCss Original Motif Original Motif BGCKGCGSGVB BBCGSCWSCBB BVCGSCKSSVB Direction: Forward Position #: 1 Overlap #: 11 Alignment: BGCKGCGSGVB BBCGSCWSCBB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Original Motif Original Motif BVCGSCKSSVB TTCAGCACCATGGACAGCKCC BBCRGCACCVBGGACAGCKCC Direction: Forward Position #: 1 Overlap #: 11 Alignment: BVCGSCKSSVB---------- TTCAGCACCATGGACAGCKCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif sssCGssGCsss Original Motif Original Motif BBCRGCACCVBGGACAGCKCC SSSCGSSGCSSS BBCVGCVSCVBGGACAGCKCC Direction: Forward Position #: 1 Overlap #: 12 Alignment: BBCRGCACCVBGGACAGCKCC SSSCGSSGCSSS--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wsAGCTACwy Combined Motif Original Motif Original Motif BBCVGCVSCVBGGACAGCKCC DVAGCTACHB BBSAGCTRCVBGGACAGCKCC Direction: Forward Position #: 2 Overlap #: 10 Alignment: BBCVGCVSCVBGGACAGCKCC -DVAGCTACHB---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 23 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 23 Motif 6 Reverse Complement Reverse Complement GGGGMGGG GGGKGGGG GGGGSGGG Direction: Backward Position #: 1 Overlap #: 8 Alignment: GGGGMGGG GGGKGGGG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif SP1 Reverse Complement Original Motif CCCSCCCC CCCCKCCCCC CCCCYCCCCC Direction: Forward Position #: 1 Overlap #: 8 Alignment: CCCSCCCC-- CCCCKCCCCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Klf4 Original Motif Reverse Complement CCCCYCCCCC GCCYCMCCCD SCCCCCCCCH Direction: Forward Position #: 1 Overlap #: 10 Alignment: CCCCYCCCCC GCCYCMCCCD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccCCmCACCcc Reverse Complement Reverse Complement DGGGGGGGGS DDGGTGRGGBD DGGGKGGGGBD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DGGGGGGGGS- DDGGTGRGGBD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Original Motif Reverse Complement DGGGKGGGGBD SSGGGCGGSGGCGSS DGGGGGVGGSGGCGSS Direction: Forward Position #: 2 Overlap #: 10 Alignment: DGGGKGGGGBD----- -SSGGGCGGSGGCGSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCrCYyYCGss Reverse Complement Original Motif SSCGCCSCCVCCCCCH BBCRCCYCCGBB BBCGCCBCCGCCCCCH Direction: Forward Position #: 1 Overlap #: 12 Alignment: SSCGCCSCCVCCCCCH BBCRCCYCCGBB---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Egr1 Reverse Complement Original Motif DGGGGGCGGBGGCGBB HGCGTGGGCGK BGSGKGSGBGKGCGBB Direction: Forward Position #: 1 Overlap #: 11 Alignment: DGGGGGCGGBGGCGBB HGCGTGGGCGK----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGMsGRGCGss Reverse Complement Reverse Complement BBCGCYCBCSCRCSCV BBCGCCCSGCVV BBCGCCCSSCCVCSCV Direction: Forward Position #: 1 Overlap #: 12 Alignment: BBCGCYCBCSCRCSCV BBCGCCCSGCVV---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RREB1 Combined Motif Reverse Complement Reverse Complement BGSGBGGSSGGGCGBB BGRRRGRGGRTGRTTYGGGG BGSGBGGVGGGGVKGVTTYGGGG Direction: Forward Position #: 4 Overlap #: 13 Alignment: BGSGBGGSSGGGCGBB------- ---BGRRRGRGGRTGRTTYGGGG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGCksCGss Original Motif Reverse Complement BGSGBGGVGGGGVKGVTTYGGGG BBCGSRGCGVV BGCGSRGCGVGGVKGVTTYGGGG Direction: Forward Position #: 1 Overlap #: 11 Alignment: BGSGBGGVGGGGVKGVTTYGGGG BBCGSRGCGVV------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 24 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 24 Motif 9 Original Motif Original Motif CTGGGA GCTGGGAW GCTGGGAW Direction: Forward Position #: 2 Overlap #: 6 Alignment: -CTGGGA- GCTGGGAW ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Reverse Complement Reverse Complement WTCCCAGC GGYGCTGTCCATGGTGCTGAA GGYGCTDTCCCWGSTGCTGAA Direction: Forward Position #: 7 Overlap #: 8 Alignment: ------WTCCCAGC------- GGYGCTGTCCATGGTGCTGAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rrAGGGGGArr Combined Motif Original Motif Reverse Complement GGYGCTDTCCCWGSTGCTGAA VVTCCCCCTVV GGYVCTCYCCCTGSTGCTGAA Direction: Forward Position #: 4 Overlap #: 11 Alignment: GGYGCTDTCCCWGSTGCTGAA ---VVTCCCCCTVV------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- MZF1_1-4 Combined Motif Reverse Complement Original Motif TTCAGCASCAGGGKGAGVKCC BGGGGA TTCAGCASCAGGGGGAGVKCC Direction: Forward Position #: 11 Overlap #: 6 Alignment: TTCAGCASCAGGGKGAGVKCC ----------BGGGGA----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccCCAGTGCAbr Original Motif Original Motif TTCAGCASCAGGGGGAGVKCC HVCCAGTGCABD HBYCAGYRCMHDGGGGAGVKCC Direction: Forward Position #: 2 Overlap #: 11 Alignment: -TTCAGCASCAGGGGGAGVKCC HVCCAGTGCABD---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RREB1 Reverse Complement Original Motif GGYVCTCCCCHHYGKMCTGKVD CCCCMAAMCAMCCMCMMMCV CCCCVRMVCWCCCCCHHVBMCTGKVD Direction: Forward Position #: 5 Overlap #: 16 Alignment: ----GGYVCTCCCCHHYGKMCTGKVD CCCCMAAMCAMCCMCMMMCV------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 16 Original Motif Original Motif CCCCVRMVCWCCCCCHHVBMCTGKVD CTGDGTTC TCCTSTGTCCCCVRMVCWCCCCCHHVBM Direction: Backward Position #: 3 Overlap #: 6 Alignment: CCCCVRMVCWCCCCCHHVBMCTGKVD-- --------------------CTGDGTTC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif INSM1 Reverse Complement Original Motif YBVDDGGGGGWGVYKBGGGGACASAGGA TGYCAGGGGGCR TGBHWGGGGGHGVYKBGGGGACASAGGA Direction: Forward Position #: 1 Overlap #: 12 Alignment: YBVDDGGGGGWGVYKBGGGGACASAGGA TGYCAGGGGGCR---------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Zfp423 Original Motif Reverse Complement TGBHWGGGGGHGVYKBGGGGACASAGGA GYRYCCMTKGGYRSC GYRYCCVKGGGYRSCKBGGGGACASAGGA Direction: Forward Position #: 2 Overlap #: 14 Alignment: -TGBHWGGGGGHGVYKBGGGGACASAGGA GYRYCCMTKGGYRSC-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- sgCTGGCCAGcs Combined Motif Reverse Complement Original Motif TCCTSTGTCCCCVRGSMMCCCYVGGKMMC BBCTGGCCAGVV TCCBCTGKCCMSVVGSMMCCCYVGGKMMC Direction: Forward Position #: 3 Overlap #: 12 Alignment: TCCTSTGTCCCCVRGSMMCCCYVGGKMMC --BBCTGGCCAGVV--------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 25 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 25 Motif 27 Original Motif Original Motif CACACAVRCACACA CAYACACACACACA CACACACACACACA Direction: Forward Position #: 1 Overlap #: 14 Alignment: CACACAVRCACACA CAYACACACACACA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yayAyAyACATrya Original Motif Original Motif CACACACACACACA HACAYAYACATRHD CACACACACAYACA Direction: Forward Position #: 1 Overlap #: 14 Alignment: CACACACACACACA HACAYAYACATRHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RREB1 Combined Motif Original Motif Original Motif CACACACACAYACA CCCCMAAMCAMCCMCMMMCV CMCMMAMACACMCMCMMMCV Direction: Forward Position #: 1 Overlap #: 14 Alignment: CACACACACAYACA------ CCCCMAAMCAMCCMCMMMCV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ryayAyAyrtGTRTrTry Reverse Complement Original Motif BGRRRGYGRGTGTRTRRGRG DHAYAYAYRTGTGTRTDH DBRBABRYRDGTGTRTRDGRG Direction: Forward Position #: 2 Overlap #: 17 Alignment: -BGRRRGYGRGTGTRTRRGRG DHAYAYAYRTGTGTRTDH--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Reverse Complement Original Motif CMCHMAMACACDMMKBTBMVD HVCATGCATGCABD HVCAYRCAYRCAHVKBTBMVD Direction: Forward Position #: 1 Overlap #: 14 Alignment: CMCHMAMACACDMMKBTBMVD HVCATGCATGCABD------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 26 Combined Motif Original Motif Reverse Complement HVCAYRCAYRCAHVKBTBMVD AAAAAAACAAARRA HAMAWAMAYAMAVVWBTBMVD Direction: Forward Position #: 2 Overlap #: 14 Alignment: HVCAYRCAYRCAHVKBTBMVD -AAAAAAACAAARRA------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RXRAVDR Combined Motif Original Motif Original Motif HAMAWAMAYAMAVVWBTBMVD GGGTCAWBGRGTTCA HAMAWAMAYAMAVRGGTCAHBGRGTTCA Direction: Forward Position #: 14 Overlap #: 8 Alignment: HAMAWAMAYAMAVVWBTBMVD------- -------------GGGTCAWBGRGTTCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Reverse Complement Reverse Complement TGAACKCVHTGACCMBTYTKTYTWTRTD SSGGGCGGSGGCGSS TGAACKCVHTGACCMBTYTKTYTWBVKGGCGGSGGCGSS Direction: Forward Position #: 25 Overlap #: 4 Alignment: TGAACKCVHTGACCMBTYTKTYTWTRTD----------- ------------------------SSGGGCGGSGGCGSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CACACACACACA Combined Motif Reverse Complement Original Motif SSCGCCSCCGCCYVVWAMAYAMAVRGGTCAHBGYGTTCA CACACACACACA SSCGCCSCCGCCHCACACACAMAVRGGTCAHBGYGTTCA Direction: Forward Position #: 12 Overlap #: 12 Alignment: SSCGCCSCCGCCYVVWAMAYAMAVRGGTCAHBGYGTTCA -----------CACACACACACA---------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACACACACACA Original Motif Original Motif SSCGCCSCCGCCHCACACACAMAVRGGTCAHBGYGTTCA CACACACACACA CVCRCMCMCACMHCACACACAMAVRGGTCAHBGYGTTCA Direction: Forward Position #: 1 Overlap #: 12 Alignment: SSCGCCSCCGCCHCACACACAMAVRGGTCAHBGYGTTCA CACACACACACA--------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 26 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 26 yayAyAyACATrya Original Motif Reverse Complement TKKTTTGTTTTTTT DHKATGTKTKTGTD TDKWTKKKTTTKTT Direction: Backward Position #: 1 Overlap #: 14 Alignment: TKKTTTGTTTTTTT DHKATGTKTKTGTD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 27 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 27 Motif 25 Original Motif Original Motif CAYACACACACACA CACACAVRCACACA CACACACACACACA Direction: Forward Position #: 1 Overlap #: 14 Alignment: CAYACACACACACA CACACAVRCACACA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yayAyAyACATrya Original Motif Original Motif CACACACACACACA HACAYAYACATRHD CACACACACAYACA Direction: Forward Position #: 1 Overlap #: 14 Alignment: CACACACACACACA HACAYAYACATRHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RREB1 Original Motif Original Motif CACACACACAYACA CCCCMAAMCAMCCMCMMMCV CMCMMAMACACMCMCMMMCV Direction: Forward Position #: 1 Overlap #: 14 Alignment: CACACACACAYACA------ CCCCMAAMCAMCCMCMMMCV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ryayAyAyrtGTRTrTry Reverse Complement Original Motif BGRRRGYGRGTGTRTRRGRG DHAYAYAYRTGTGTRTDH DBRBABRYRDGTGTRTRDGRG Direction: Forward Position #: 2 Overlap #: 17 Alignment: -BGRRRGYGRGTGTRTRRGRG DHAYAYAYRTGTGTRTDH--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- AAAAAAAAAAA Combined Motif Reverse Complement Reverse Complement CMCHMAMACACDMMKBTBMVD DVTGCATGCATGBH CMCHHAYRCAYGCATGKHMVD Direction: Forward Position #: 5 Overlap #: 14 Alignment: CMCHMAMACACDMMKBTBMVD ----DVTGCATGCATGBH--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 26 Combined Motif Original Motif Reverse Complement CMCHHAYRCAYGCATGKHMVD AAAAAAACAAARRA CMCHHAYRCAYGCATGKAMADAAACAAARRA Direction: Forward Position #: 18 Overlap #: 4 Alignment: CMCHHAYRCAYGCATGKHMVD---------- -----------------AAAAAAACAAARRA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACACACACACA Original Motif Original Motif CMCHHAYRCAYGCATGKAMADAAACAAARRA CACACACACACA CACACAYACAYRCATGKAMADAAACAAARRA Direction: Forward Position #: 1 Overlap #: 12 Alignment: CMCHHAYRCAYGCATGKAMADAAACAAARRA CACACACACACA------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CACACACACACA Combined Motif Original Motif Original Motif CACACAYACAYRCATGKAMADAAACAAARRA CACACACACACA CACACACACACACAYRKAMADAAACAAARRA Direction: Forward Position #: 5 Overlap #: 12 Alignment: CACACAYACAYRCATGKAMADAAACAAARRA ----CACACACACACA--------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif tyTCTkTkTCyy Original Motif Reverse Complement CACACACACACACAYRKAMADAAACAAARRA VHGARAYAGAVV HMSAVACASACACAYRKAMADAAACAAARRA Direction: Forward Position #: 1 Overlap #: 12 Alignment: CACACACACACACAYRKAMADAAACAAARRA VHGARAYAGAVV------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif INSM1 Reverse Complement Original Motif TKKTTTGTTTDTYTRKMTGTGTSTGTBTSYD TGYCAGGGGGCR GGGGCRTGTCWGTKKTTTGTTTDTYTRKMTGTGTSTG Direction: Backward Position #: 7 Overlap #: 6 Alignment: TKKTTTGTTTDTYTRKMTGTGTSTGTBTSYD------ -------------------------TGYCAGGGGGCR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 28 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfx ssCGCCsCCrCCCss Original Motif Original Motif BBVGCCBVGGCCTV SSCGCCSCCGCCCSS SBCGCCSMSGCCYVS Direction: Forward Position #: 1 Overlap #: 14 Alignment: BBVGCCBVGGCCTV- SSCGCCSCCGCCCSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Pax5 Reverse Complement Reverse Complement SVMGGCSRSGGCGBS MSGKKRCGCWDCABTGBBCD VSRGGVCGCKBCVBBGBBCD Direction: Forward Position #: 1 Overlap #: 15 Alignment: SVMGGCSRSGGCGBS----- MSGKKRCGCWDCABTGBBCD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Original Motif Original Motif VSRGGVCGCKBCVBBGBBCD VHRGGTCABDBTGMCCTB VVRGGHCRCDBYGVYVYBCD Direction: Forward Position #: 1 Overlap #: 18 Alignment: VSRGGVCGCKBCVBBGBBCD VHRGGTCABDBTGMCCTB-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Original Motif Reverse Complement VVRGGHCRCDBYGVYVYBCD MGGTCAGGGTGACCTRDBHV MDGKSASRSTGHSCBVBBMD Direction: Forward Position #: 1 Overlap #: 20 Alignment: VVRGGHCRCDBYGVYVYBCD MGGTCAGGGTGACCTRDBHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Tcfcp2l1 Reverse Complement Reverse Complement HRBVVVGSHCASMSTSRCHY CKGGDTBDMMCTGG CDGGDBHDVHCDGGSTSRCHY Direction: Forward Position #: 2 Overlap #: 13 Alignment: -HRBVVVGSHCASMSTSRCHY CKGGDTBDMMCTGG------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfp423 Combined Motif Original Motif Reverse Complement CDGGDBHDVHCDGGSTSRCHY GYRYCCMTKGGYRSC CDGGRBRBCCCWKGGYRSCHY Direction: Forward Position #: 5 Overlap #: 15 Alignment: CDGGDBHDVHCDGGSTSRCHY ----GYRYCCMTKGGYRSC-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PLAG1 Reverse Complement Original Motif MDGSMMCCYWGGGVKBMCCDG GGGGCCCAAGGGGG GVGGCCMHMBGGGGVKBMCCDG Direction: Forward Position #: 2 Overlap #: 13 Alignment: -MDGSMMCCYWGGGVKBMCCDG GGGGCCCAAGGGGG-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Original Motif Original Motif GVGGCCMHMBGGGGVKBMCCDG TTCAGCACCATGGACAGCKCC TKCRGCMCCMBGGRSAGBVCCDG Direction: Forward Position #: 2 Overlap #: 20 Alignment: -GVGGCCMHMBGGGGVKBMCCDG TTCAGCACCATGGACAGCKCC-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Original Motif Original Motif TKCRGCMCCMBGGRSAGBVCCDG HWDAGHACRHHVTGTHCCHVMV HDVRGVACVHBGKGBASCHVCVG Direction: Forward Position #: 1 Overlap #: 22 Alignment: TKCRGCMCCMBGGRSAGBVCCDG HWDAGHACRHHVTGTHCCHVMV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Reverse Complement Original Motif CVGVDGSTVCYCBDBGTVCKVDH BTRGGDCARAGGKCA CVGVBRGDVCAVDGKKYACKVDH Direction: Forward Position #: 4 Overlap #: 15 Alignment: CVGVDGSTVCYCBDBGTVCKVDH ---BTRGGDCARAGGKCA----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 29 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfp423 Ar Original Motif Original Motif GSMMCCYARGGKKKC HWDAGHACRHHVTGTHCCHVMV HVMVRGMACMYHRKGTDCCHWD Direction: Backward Position #: 5 Overlap #: 15 Alignment: ---GSMMCCYARGGKKKC---- HWDAGHACRHHVTGTHCCHVMV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Reverse Complement Original Motif DWHGGDACYMHKRGTYCMVRVD DGVBCABTGDWGCGKRRCSR DRHGSDVCBVWGVGTHVCSRVD Direction: Forward Position #: 1 Overlap #: 20 Alignment: DWHGGDACYMHKRGTYCMVRVD DGVBCABTGDWGCGKRRCSR-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- REST Combined Motif Reverse Complement Reverse Complement HVMSGVHACVCWBBGBDSCHMD GGYGCTGTCCATGGTGCTGAA HGVHGCTRYCCHBGGTBCYGMD Direction: Forward Position #: 2 Overlap #: 21 Alignment: HVMSGVHACVCWBBGBDSCHMD -GGYGCTGTCCATGGTGCTGAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ryayAyAyrtGTRTrTry Reverse Complement Original Motif DYCMGBACCVHGGKMAGCDVCD DHAYAYAYRTGTGTRTDH DYVHRYACVHDKGTVHVHDVCD Direction: Forward Position #: 1 Overlap #: 18 Alignment: DYCMGBACCVHGGKMAGCDVCD DHAYAYAYRTGTGTRTDH---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RXRAVDR Combined Motif Original Motif Original Motif DYVHRYACVHDKGTVHVHDVCD GGGTCAWBGRGTTCA DYVHRYACVHGGGTCADHGRGTTCA Direction: Forward Position #: 11 Overlap #: 12 Alignment: DYVHRYACVHDKGTVHVHDVCD--- ----------GGGTCAWBGRGTTCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PLAG1 Combined Motif Reverse Complement Reverse Complement TGAACMCDDTGACCCHVGTKKDBMD CCCCCTTGGGCCCC TGMMCCCBWDGRCCCCVGTKKDBMD Direction: Forward Position #: 3 Overlap #: 14 Alignment: TGAACMCDDTGACCCHVGTKKDBMD --CCCCCTTGGGCCCC--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfx Combined Motif Reverse Complement Original Motif DYVHRYACVGGGGMCDWVGGGRYCA BBVGCCBVGGCCTV DYVBVBRCCBRGGCCTDVGGGRYCA Direction: Forward Position #: 4 Overlap #: 14 Alignment: DYVHRYACVGGGGMCDWVGGGRYCA ---BBVGCCBVGGCCTV-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Reverse Complement Reverse Complement TGMMCCCBDAGGCCMBGGKBVBBMD MGGTCAGGGTGACCTRDBHV HGVHCMVBBWGRCCHVGGBVVBBMD Direction: Forward Position #: 1 Overlap #: 20 Alignment: TGMMCCCBDAGGCCMBGGKBVBBMD MGGTCAGGGTGACCTRDBHV----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RREB1 Reverse Complement Original Motif DYVBVVVCCVHGGMCWBBVYGHVCH CCCCMAAMCAMCCMCMMMCV HCMCMMACCAMSSMCHHHSHGHVCH Direction: Forward Position #: 1 Overlap #: 20 Alignment: DYVBVVVCCVHGGMCWBBVYGHVCH CCCCMAAMCAMCCMCMMMCV----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCrCYyYCGss Combined Motif Reverse Complement Reverse Complement HGVHCDSDDHGRSSRTGGTYYGRGD BBCGGKGGMGBB HGVHCBSCGBGGGCGBGGTYYGRGD Direction: Forward Position #: 6 Overlap #: 12 Alignment: HGVHCDSDDHGRSSRTGGTYYGRGD -----BBCGGKGGMGBB-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 30 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ZEB1 RORA_1 Original Motif Reverse Complement CACCTD TGACCTDVWT VWTSACCTDT Direction: Backward Position #: 4 Overlap #: 6 Alignment: -CACCTD--- TGACCTDVWT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Original Motif Original Motif VWTSACCTDT TTCAGCACCATGGACAGCKCC TTSAKSACCWDKGACAGCKCC Direction: Forward Position #: 3 Overlap #: 10 Alignment: --VWTSACCTDT--------- TTCAGCACCATGGACAGCKCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccCCmCACCcc Original Motif Original Motif TTSAKSACCWDKGACAGCKCC HBCCMCACCHH BBCMVCACCHHKGACAGCKCC Direction: Forward Position #: 1 Overlap #: 11 Alignment: TTSAKSACCWDKGACAGCKCC HBCCMCACCHH---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rrAGGGGGArr Original Motif Reverse Complement BBCMVCACCHHKGACAGCKCC VVTCCCCCTVV HHYCCCMCYHHKGACAGCKCC Direction: Forward Position #: 1 Overlap #: 11 Alignment: BBCMVCACCHHKGACAGCKCC VVTCCCCCTVV---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Arnt Combined Motif Reverse Complement Original Motif GGYGCTGTCRDDMGRGGGMDD CACGTG GGYGCTGTCRVACGTGGGMDD Direction: Forward Position #: 11 Overlap #: 6 Alignment: GGYGCTGTCRDDMGRGGGMDD ----------CACGTG----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Esrrb Combined Motif Reverse Complement Original Motif HHYCCCACGTVKGACAGCKCC CACGTG HHYCMCGYGTVKGACAGCKCC Direction: Forward Position #: 4 Overlap #: 6 Alignment: HHYCCCACGTVKGACAGCKCC ---CACGTG------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 31 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TFAP2A Zfx Reverse Complement Original Motif SCMVBBGGC BBVGCCBVGGCCTV TVSCCBVGGSCBBV Direction: Backward Position #: 3 Overlap #: 9 Alignment: ---SCMVBBGGC-- BBVGCCBVGGCCTV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssGMsGRGCGss Combined Motif Original Motif Original Motif TVSCCBVGGSCBBV VVGCSGGGCGBB TVVSSCVGGGCGBV Direction: Forward Position #: 3 Overlap #: 12 Alignment: TVSCCBVGGSCBBV --VVGCSGGGCGBB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PLAG1 Reverse Complement Original Motif VBCGCCCVGSSVVA GGGGCCCAAGGGGG GGSGCCCHVGGGGR Direction: Forward Position #: 1 Overlap #: 14 Alignment: VBCGCCCVGSSVVA GGGGCCCAAGGGGG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Zfp423 Original Motif Original Motif GGSGCCCHVGGGGR GSMMCCYARGGKKKC GSVVCCYARGGGKDC Direction: Forward Position #: 1 Overlap #: 14 Alignment: GGSGCCCHVGGGGR- GSMMCCYARGGKKKC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Reverse Complement Original Motif GHYCCCKTKGGVVSC VDBHMAGGTCACCCTGACCY RVBCCMGKKSRVVSYGACCY Direction: Forward Position #: 1 Overlap #: 15 Alignment: GHYCCCKTKGGVVSC----- VDBHMAGGTCACCCTGACCY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCrCYyYCGss Original Motif Reverse Complement RVBCCMGKKSRVVSYGACCY BBCGGKGGMGBB VVCGSVGGHGVVVSYGACCY Direction: Forward Position #: 1 Overlap #: 12 Alignment: RVBCCMGKKSRVVSYGACCY BBCGGKGGMGBB-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- sssCGssGCsss Combined Motif Original Motif Reverse Complement VVCGSVGGHGVVVSYGACCY SSSGCSSCGSSS VVCGSVGGCGSCGSBGACCY Direction: Forward Position #: 5 Overlap #: 12 Alignment: VVCGSVGGHGVVVSYGACCY ----SSSGCSSCGSSS---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Original Motif Original Motif VVCGSVGGCGSCGSBGACCY VHRGGTCABDBTGMCCTB VVCDVGGKCRVBGBBVMCYB Direction: Forward Position #: 3 Overlap #: 18 Alignment: VVCGSVGGCGSCGSBGACCY --VHRGGTCABDBTGMCCTB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Mycn Original Motif Reverse Complement VVCDVGGKCRVBGBBVMCYB GCCACGTGSD GCCVCGKGCRVBGBBVMCYB Direction: Forward Position #: 1 Overlap #: 10 Alignment: VVCDVGGKCRVBGBBVMCYB GCCACGTGSD---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Reverse Complement Original Motif VKGRVBVCBVKGCRCGBGGC DGVBCABTGDWGCGKRRCSR VGGDVVVYGVDGCRBRDSSV Direction: Forward Position #: 1 Overlap #: 20 Alignment: VKGRVBVCBVKGCRCGBGGC DGVBCABTGDWGCGKRRCSR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 32 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- SP1 ssCGCCsCCrCCCss Reverse Complement Reverse Complement GGGGGYGGGG SSGGGCGGSGGCGSS GCGSSGGGGGYGGGG Direction: Backward Position #: 6 Overlap #: 10 Alignment: GGGGGYGGGG----- SSGGGCGGSGGCGSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCrCYyYCGss Reverse Complement Original Motif CCCCKCCCCCSSCGC BBCRCCYCCGBB CCCSCCCCCGSBCGC Direction: Forward Position #: 1 Overlap #: 12 Alignment: CCCCKCCCCCSSCGC BBCRCCYCCGBB--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccCCmCACCcc Original Motif Original Motif CCCSCCCCCGSBCGC HBCCMCACCHH CBCCCCMCCBBBCGC Direction: Forward Position #: 1 Overlap #: 11 Alignment: CCCSCCCCCGSBCGC HBCCMCACCHH---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RREB1 Combined Motif Original Motif Original Motif CBCCCCMCCBBBCGC CCCCMAAMCAMCCMCMMMCV CBCCCCMMMVCACSCMCMMMCV Direction: Forward Position #: 3 Overlap #: 13 Alignment: CBCCCCMCCBBBCGC------- --CCCCMAAMCAMCCMCMMMCV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Zfx Original Motif Reverse Complement CBCCCCMMMVCACSCMCMMMCV VAGGCCBBGGCVBB VASSCCHHVSCVCSCMCMMMCV Direction: Forward Position #: 1 Overlap #: 14 Alignment: CBCCCCMMMVCACSCMCMMMCV VAGGCCBBGGCVBB-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PLAG1 Original Motif Reverse Complement VASSCCHHVSCVCSCMCMMMCV CCCCCTTGGGCCCC CMCCCYWVGSCCCCCMCMMMCV Direction: Forward Position #: 1 Overlap #: 14 Alignment: VASSCCHHVSCVCSCMCMMMCV CCCCCTTGGGCCCC-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Reverse Complement Original Motif BGRRRGRGGGGGSCVWKGGGRG BTRGGDCARAGGKCA BGVDRGGGSRRRGSBHDGGGRG Direction: Forward Position #: 3 Overlap #: 15 Alignment: BGRRRGRGGGGGSCVWKGGGRG --BTRGGDCARAGGKCA----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Klf4 Original Motif Original Motif BGVDRGGGSRRRGSBHDGGGRG DGGGYGKGGC DGGGHGGGGVRRGSBHDGGGRG Direction: Forward Position #: 1 Overlap #: 10 Alignment: BGVDRGGGSRRRGSBHDGGGRG DGGGYGKGGC------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssGMsGRGCGss Combined Motif Reverse Complement Reverse Complement CMCCCDDVSCMMVCCCCHCCCD BBCGCCCSGCVV CMCCCBCGCCMVRCCBCHCCCD Direction: Forward Position #: 5 Overlap #: 12 Alignment: CMCCCDDVSCMMVCCCCHCCCD ----BBCGCCCSGCVV------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rrAGGGGGArr Combined Motif Reverse Complement Original Motif DGGGHGBGGMVRGGCGBGGGRG VVAGGGGGAVV DGGGVRGGGGGAGGCGBGGGRG Direction: Forward Position #: 4 Overlap #: 11 Alignment: DGGGHGBGGMVRGGCGBGGGRG ---VVAGGGGGAVV-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 33 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RXRAVDR Ar Reverse Complement Original Motif TGAACKCBWTGACCC HWDAGHACRHHVTGTHCCHVMV HVMVDGAACDCBHTGWCCCHWD Direction: Backward Position #: 5 Overlap #: 15 Alignment: ---TGAACKCBWTGACCC---- HWDAGHACRHHVTGTHCCHVMV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Original Motif Reverse Complement HVMVDGAACDCBHTGWCCCHWD BAGGYCABHBTGACCKHV HVMVAGRACAHBVTGACCBHDD Direction: Forward Position #: 4 Overlap #: 18 Alignment: HVMVDGAACDCBHTGWCCCHWD ---BAGGYCABHBTGACCKHV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RXRRAR_DR5 Combined Motif Reverse Complement Reverse Complement DDHBGGTCAVBDTGTKCTVRVD TGACCTCKVVBTGAYCK DTDDSSTCWVVDTGABCKVRVD Direction: Forward Position #: 2 Overlap #: 17 Alignment: DDHBGGTCAVBDTGTKCTVRVD -TGACCTCKVVBTGAYCK---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Original Motif Reverse Complement DTDDSSTCWVVDTGABCKVRVD MGGTCAGGGTGACCTRDBHV DTDVGGTCAVVBTGACCTVRVHV Direction: Forward Position #: 4 Overlap #: 19 Alignment: DTDDSSTCWVVDTGABCKVRVD- ---MGGTCAGGGTGACCTRDBHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Zfp423 Reverse Complement Reverse Complement VDVMVAGGTCABVVTGACCBHAD GYRYCCMTKGGYRSC GYRBCCMWGGKCASCVTGACCBHAD Direction: Forward Position #: 3 Overlap #: 13 Alignment: --VDVMVAGGTCABVVTGACCBHAD GYRYCCMTKGGYRSC---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 34 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RREB1 ESR1 Reverse Complement Reverse Complement BGRRRGRGGRTGRTTYGGGG MGGTCAGGGTGACCTRDBHV VVGGDSAGGGTGRYYTGGGVB Direction: Backward Position #: 2 Overlap #: 19 Alignment: BGRRRGRGGRTGRTTYGGGG- -MGGTCAGGGTGACCTRDBHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Ar Original Motif Reverse Complement VVGGDSAGGGTGRYYTGGGVB VRVDGGHACAVDDKGTHCTDWH VRVVGGDWCAGGDTGWYCTDDBVB Direction: Forward Position #: 4 Overlap #: 19 Alignment: ---VVGGDSAGGGTGRYYTGGGVB VRVDGGHACAVDDKGTHCTDWH-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Original Motif Reverse Complement VRVVGGDWCAGGDTGWYCTDDBVB BAGGYCABHBTGACCKHV VRVVVGGHCAVBBTGACCKDDBVB Direction: Forward Position #: 4 Overlap #: 18 Alignment: VRVVGGDWCAGGDTGWYCTDDBVB ---BAGGYCABHBTGACCKHV--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Pax5 Original Motif Original Motif VRVVVGGHCAVBBTGACCKDDBVB DGVBCABTGDWGCGKRRCSR DGVBVRVBVRDGCRBVDYGRCCKDDBVB Direction: Forward Position #: 5 Overlap #: 16 Alignment: ----VRVVVGGHCAVBBTGACCKDDBVB DGVBCABTGDWGCGKRRCSR-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Reverse Complement Reverse Complement BVBHDRGGKCMHVVKGCHMVVVKVBBCD SSGGGCGGSGGCGSS BVSGGVGGBSVCGVBGCHMVVVKVBBCD Direction: Forward Position #: 1 Overlap #: 15 Alignment: BVBHDRGGKCMHVVKGCHMVVVKVBBCD SSGGGCGGSGGCGSS------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PLAG1 Reverse Complement Original Motif HGVBVRVBVRDGCBVCGVSBCCBCCSVB GGGGCCCAAGGGGG GGGGCBVAVBGGGGCBVCGVSBCCBCCSVB Direction: Forward Position #: 3 Overlap #: 12 Alignment: --HGVBVRVBVRDGCBVCGVSBCCBCCSVB GGGGCCCAAGGGGG---------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 25 Original Motif Original Motif GGGGCBVAVBGGGGCBVCGVSBCCBCCSVB CACACAVRCACACA RCACACACASACVCGGGGCBVAVBGGGGCBVCGVSBC Direction: Backward Position #: 8 Overlap #: 7 Alignment: GGGGCBVAVBGGGGCBVCGVSBCCBCCSVB------- -----------------------CACACAVRCACACA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yayAyAyACATrya Original Motif Original Motif RCACACACASACVCGGGGCBVAVBGGGGCBVCGVSBC HACAYAYACATRHD HACACACACABRCVCGGGGCBVAVBGGGGCBVCGVSBC Direction: Forward Position #: 2 Overlap #: 13 Alignment: -RCACACACASACVCGGGGCBVAVBGGGGCBVCGVSBC HACAYAYACATRHD------------------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 27 Original Motif Original Motif HACACACACABRCVCGGGGCBVAVBGGGGCBVCGVSBC CAYACACACACACA CACACACACACACACGGGGCBVAVBGGGGCBVCGVSBC Direction: Forward Position #: 1 Overlap #: 14 Alignment: HACACACACABRCVCGGGGCBVAVBGGGGCBVCGVSBC CAYACACACACACA------------------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RXRRAR_DR5 Combined Motif Reverse Complement Reverse Complement GBSVCGVBGCCCCBBTVBGCCCCGTGTGTGTGTGTGTG TGACCTCKVVBTGAYCK GBSVCGVTGMCCYCBHVBKSMCCKTGTGTGTGTGTGTG Direction: Forward Position #: 8 Overlap #: 17 Alignment: GBSVCGVBGCCCCBBTVBGCCCCGTGTGTGTGTGTGTG -------TGACCTCKVVBTGAYCK-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 35 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- REST Ar Reverse Complement Reverse Complement GGYGCTGTCCATGGTGCTGAA VRVDGGHACAVDDKGTHCTDWH GVHGSTRYMCDDKGTBCTKAHV Direction: Backward Position #: 1 Overlap #: 21 Alignment: -GGYGCTGTCCATGGTGCTGAA VRVDGGHACAVDDKGTHCTDWH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Pax5 Original Motif Reverse Complement GVHGSTRYMCDDKGTBCTKAHV MSGKKRCGCWDCABTGBBCD MSGKKRCGCTDCMSDDBGYDCTKAHV Direction: Forward Position #: 5 Overlap #: 16 Alignment: ----GVHGSTRYMCDDKGTBCTKAHV MSGKKRCGCWDCABTGBBCD------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Original Motif Reverse Complement MSGKKRCGCTDCMSDDBGYDCTKAHV MGGTCAGGGTGACCTRDBHV MGGTBAVGSTGHCCTDBBHBCTKAHV Direction: Forward Position #: 1 Overlap #: 20 Alignment: MSGKKRCGCTDCMSDDBGYDCTKAHV MGGTCAGGGTGACCTRDBHV------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Original Motif Original Motif MGGTBAVGSTGHCCTDBBHBCTKAHV VHRGGTCABDBTGMCCTB MGGTBVHRGKKCMBDDTGHHCTBAHV Direction: Forward Position #: 6 Overlap #: 18 Alignment: MGGTBAVGSTGHCCTDBBHBCTKAHV -----VHRGGTCABDBTGMCCTB--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- HNF4A Combined Motif Reverse Complement Original Motif VHTBAGDHCAHDBYGRYCMHBBACCY RGGBCAAAGKYCA VHTBAGGBCAVAGKBVHCMHBBACCY Direction: Forward Position #: 5 Overlap #: 13 Alignment: VHTBAGDHCAHDBYGRYCMHBBACCY ----RGGBCAAAGKYCA--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Reverse Complement Original Motif MGGTBVHRGHVBRCTBTGBCCTBAHV BTRGGDCARAGGKCA MGGTBVHRGDVCAVWGKKBMCTBAHV Direction: Forward Position #: 6 Overlap #: 15 Alignment: MGGTBVHRGHVBRCTBTGBCCTBAHV -----BTRGGDCARAGGKCA------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Original Motif Reverse Complement MGGTBVHRGDVCAVWGKKBMCTBAHV SSGGGCGGSGGCGSS MGGBSGGGVGGSRSHGKBBMCTBAHV Direction: Forward Position #: 4 Overlap #: 15 Alignment: MGGTBVHRGDVCAVWGKKBMCTBAHV ---SSGGGCGGSGGCGSS-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGCTswGCCms Original Motif Original Motif MGGBSGGGVGGSRSHGKBBMCTBAHV VBGCTSAGCCHB VVGCTSDGCSVBRSHGKBBMCTBAHV Direction: Forward Position #: 1 Overlap #: 12 Alignment: MGGBSGGGVGGSRSHGKBBMCTBAHV VBGCTSAGCCHB-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCrCYyYCGss Original Motif Reverse Complement VVGCTSDGCSVBRSHGKBBMCTBAHV BBCGGKGGMGBB VVSSKGGGCGBBRSHGKBBMCTBAHV Direction: Forward Position #: 1 Overlap #: 12 Alignment: VVGCTSDGCSVBRSHGKBBMCTBAHV BBCGGKGGMGBB-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Tcfcp2l1 Combined Motif Original Motif Reverse Complement VVSSKGGGCGBBRSHGKBBMCTBAHV CKGGDTBDMMCTGG CDGGKBDGMVCBGGHGKBBMCTBAHV Direction: Forward Position #: 1 Overlap #: 14 Alignment: VVSSKGGGCGBBRSHGKBBMCTBAHV CKGGDTBDMMCTGG------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 36 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA NR1H2RXRA Original Motif Original Motif BTRGGDCARAGGKCA AAAGGTCAAAGGTCAAC ACVDRGGTCAAAGGTCA Direction: Backward Position #: 3 Overlap #: 15 Alignment: BTRGGDCARAGGKCA-- AAAGGTCAAAGGTCAAC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RXRRAR_DR5 Reverse Complement Reverse Complement TGACCTTTGACCKDBGT TGACCTCKVVBTGAYCK TGACCTBTSVCYKAYCT Direction: Forward Position #: 1 Overlap #: 17 Alignment: TGACCTTTGACCKDBGT TGACCTCKVVBTGAYCK ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Original Motif Reverse Complement TGACCTBTSVCYKAYCT BAGGYCABHBTGACCKHV TGASSTCWBVBTGACCKHV Direction: Forward Position #: 2 Overlap #: 16 Alignment: TGACCTBTSVCYKAYCT-- -BAGGYCABHBTGACCKHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Reverse Complement Original Motif VHRGGTCABVBWGASSTCA HWDAGHACRHHVTGTHCCHVMV VHDDRKCACRBHVHGBWCMHVMV Direction: Forward Position #: 2 Overlap #: 18 Alignment: VHRGGTCABVBWGASSTCA---- -HWDAGHACRHHVTGTHCCHVMV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Pax5 Original Motif Reverse Complement VHDDRKCACRBHVHGBWCMHVMV MSGKKRCGCWDCABTGBBCD MVRDDDCRCDBHVDBBHBMDVMV Direction: Forward Position #: 1 Overlap #: 20 Alignment: VHDDRKCACRBHVHGBWCMHVMV MSGKKRCGCWDCABTGBBCD--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Original Motif Reverse Complement MVRDDDCRCDBHVDBBHBMDVMV MGGTCAGGGTGACCTRDBHV MGGTCAGDDTSACHTVVBBBHBMDVMV Direction: Forward Position #: 5 Overlap #: 16 Alignment: ----MVRDDDCRCDBHVDBBHBMDVMV MGGTCAGGGTGACCTRDBHV------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RREB1 Original Motif Reverse Complement MGGTCAGDDTSACHTVVBBBHBMDVMV BGRRRGRGGRTGRTTYGGGG BVGGDSRGGGTGRYYTGGGGBHBMDVMV Direction: Forward Position #: 2 Overlap #: 19 Alignment: -MGGTCAGDDTSACHTVVBBBHBMDVMV BGRRRGRGGRTGRTTYGGGG-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- REST Combined Motif Original Motif Reverse Complement BVGGDSRGGGTGRYYTGGGGBHBMDVMV GGYGCTGTCCATGGTGCTGAA BVGGDGRVGSTGDCCHDGGTBCTVVVMV Direction: Forward Position #: 6 Overlap #: 21 Alignment: BVGGDSRGGGTGRYYTGGGGBHBMDVMV -----GGYGCTGTCCATGGTGCTGAA-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NR2F1 Reverse Complement Original Motif VRBBVAGBACCHHGGDCASCVMCDCCVB TGAMCTTTGMMCYT TGAVCTBWGVACCBHGGDCASCVMCDCCVB Direction: Forward Position #: 3 Overlap #: 12 Alignment: --VRBBVAGBACCHHGGDCASCVMCDCCVB TGAMCTTTGMMCYT---------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PLAG1 Original Motif Reverse Complement TGAVCTBWGVACCBHGGDCASCVMCDCCVB CCCCCTTGGGCCCC GGGCCCCSHCMCYHTGAVCTBWGVACCBHGGDCASCV Direction: Backward Position #: 8 Overlap #: 7 Alignment: TGAVCTBWGVACCBHGGDCASCVMCDCCVB------- -----------------------CCCCCTTGGGCCCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 37 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PLAG1 Zfp423 Original Motif Original Motif GGGGCCCAAGGGGG GSMMCCYARGGKKKC GGSVCCYARGGGGGC Direction: Forward Position #: 1 Overlap #: 14 Alignment: GGGGCCCAAGGGGG- GSMMCCYARGGKKKC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RREB1 Combined Motif Original Motif Reverse Complement GGSVCCYARGGGGGC BGRRRGRGGRTGRTTYGGGG GGBGSCHRRGGGKGVTTYGGGG Direction: Forward Position #: 3 Overlap #: 13 Alignment: GGSVCCYARGGGGGC------- --BGRRRGRGGRTGRTTYGGGG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Original Motif Reverse Complement GGBGSCHRRGGGKGVTTYGGGG SSGGGCGGSGGCGSS GGBGSSGGGVGGKGSYKBGGGG Direction: Forward Position #: 5 Overlap #: 15 Alignment: GGBGSCHRRGGGKGVTTYGGGG ----SSGGGCGGSGGCGSS--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Original Motif Original Motif GGBGSSGGGVGGKGSYKBGGGG BTRGGDCARAGGKCA GGBBVGGGSARRGGBCDBGGGG Direction: Forward Position #: 3 Overlap #: 15 Alignment: GGBGSSGGGVGGKGSYKBGGGG --BTRGGDCARAGGKCA----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfx Combined Motif Reverse Complement Reverse Complement CCCCVDGBCCKMTSCCCVBBCC VAGGCCBBGGCVBB CCCCVAGGCCKCKSCCBVBBCC Direction: Forward Position #: 5 Overlap #: 14 Alignment: CCCCVDGBCCKMTSCCCVBBCC ----VAGGCCBBGGCVBB---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Tcfcp2l1 Reverse Complement Reverse Complement GGBBVBGGSYGRGGCCTVGGGG CKGGDTBDMMCTGG SKGGDBBDVHCDGGCCTVGGGG Direction: Forward Position #: 1 Overlap #: 14 Alignment: GGBBVBGGSYGRGGCCTVGGGG CKGGDTBDMMCTGG-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RXRRAR_DR5 Original Motif Original Motif SKGGDBBDVHCDGGCCTVGGGG RGKTCABVVRGAGGTCA VGGKBABVVHSAGGYCWVGGGG Direction: Forward Position #: 1 Overlap #: 17 Alignment: SKGGDBBDVHCDGGCCTVGGGG RGKTCABVVRGAGGTCA----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Original Motif Original Motif VGGKBABVVHSAGGYCWVGGGG DGVBCABTGDWGCGKRRCSR VGDKCABBGDVGSGTVDCSRGG Direction: Forward Position #: 1 Overlap #: 20 Alignment: VGGKBABVVHSAGGYCWVGGGG DGVBCABTGDWGCGKRRCSR-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RXRAVDR Combined Motif Original Motif Original Motif VGDKCABBGDVGSGTVDCSRGG GGGTCAWBGRGTTCA VGDKCABBGDRGGKYAHVGRGKTCA Direction: Forward Position #: 11 Overlap #: 12 Alignment: VGDKCABBGDVGSGTVDCSRGG--- ----------GGGTCAWBGRGTTCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif HNF4A Original Motif Original Motif VGDKCABBGDRGGKYAHVGRGKTCA RGGBCAAAGKYCA RGDBCAVDGDBSRKYAHVGRGKTCA Direction: Forward Position #: 1 Overlap #: 13 Alignment: VGDKCABBGDRGGKYAHVGRGKTCA RGGBCAAAGKYCA------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 38 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR2F1 NR1H2RXRA Original Motif Reverse Complement TGAMCTTTGMMCYT GTTGACCTTTGACCTTT TTGACCTTTGACCTTGT Direction: Backward Position #: 2 Overlap #: 14 Alignment: --TGAMCTTTGMMCYT- GTTGACCTTTGACCTTT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Reverse Complement Original Motif ACAAGGTCAAAGGTCAA BTRGGDCARAGGKCA ASDRGGKCAAAGGTCAA Direction: Forward Position #: 2 Overlap #: 15 Alignment: ACAAGGTCAAAGGTCAA -BTRGGDCARAGGKCA- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RXRRAR_DR5 Original Motif Original Motif ASDRGGKCAAAGGTCAA RGKTCABVVRGAGGTCA RRBTVRDBSARAGGTCAA Direction: Forward Position #: 2 Overlap #: 16 Alignment: -ASDRGGKCAAAGGTCAA RGKTCABVVRGAGGTCA- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ryayAyAyrtGTRTrTry Reverse Complement Original Motif TTGACCTKTSBHKVABMK DHAYAYAYRTGTGTRTDH DTWBACMTDTGTVTRWVHK Direction: Forward Position #: 2 Overlap #: 17 Alignment: -TTGACCTKTSBHKVABMK DHAYAYAYRTGTGTRTDH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Original Motif Reverse Complement DTWBACMTDTGTVTRWVHK BAGGYCABHBTGACCKHV DTWBASVYVWBBVTGACCKHV Direction: Forward Position #: 4 Overlap #: 16 Alignment: DTWBACMTDTGTVTRWVHK-- ---BAGGYCABHBTGACCKHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Reverse Complement Reverse Complement VHRGGTCAVVBWVMVSTBWAD GGYGCTGTCCATGGTGCTGAA GGYGCTGTCCHWGGKDCWGAVWVMVSTBWAD Direction: Forward Position #: 11 Overlap #: 11 Alignment: ----------VHRGGTCAVVBWVMVSTBWAD GGYGCTGTCCATGGTGCTGAA---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Reverse Complement Original Motif DTWBASVYVWBTCWGHRCCWHGGACAGCKCC DGVBCABTGDWGCGKRRCSR DDDBMVVTVDDGCRKVRCCDHGGACAGCKCC Direction: Forward Position #: 1 Overlap #: 20 Alignment: DTWBASVYVWBTCWGHRCCWHGGACAGCKCC DGVBCABTGDWGCGKRRCSR----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- HNF4A Combined Motif Reverse Complement Original Motif GGYGCTGTCCHDGGKBYMGCDDVAVBYBDHD RGGBCAAAGKYCA GGYGCTGTCCADRGKBCMGCDDVAVBYBDHD Direction: Forward Position #: 6 Overlap #: 13 Alignment: GGYGCTGTCCHDGGKBYMGCDDVAVBYBDHD -----RGGBCAAAGKYCA------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfx Combined Motif Original Motif Original Motif GGYGCTGTCCADRGKBCMGCDDVAVBYBDHD BBVGCCBVGGCCTV GGYGCBGBSCMDRGGCCTGCDDVAVBYBDHD Direction: Forward Position #: 6 Overlap #: 14 Alignment: GGYGCTGTCCADRGKBCMGCDDVAVBYBDHD -----BBVGCCBVGGCCTV------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Original Motif Original Motif GGYGCBGBSCMDRGGCCTGCDDVAVBYBDHD VDBHMAGGTCACCCTGACCY GGYGCBVDBCMDGGKCMHVCTGVCCBYBDHD Direction: Forward Position #: 7 Overlap #: 20 Alignment: GGYGCBGBSCMDRGGCCTGCDDVAVBYBDHD ------VDBHMAGGTCACCCTGACCY----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 39 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- MZF1_1-4 rrAGGGGGArr Reverse Complement Reverse Complement TCCCCV VVTCCCCCTVV VVTCCCCCTVV Direction: Forward Position #: 3 Overlap #: 6 Alignment: --TCCCCV--- VVTCCCCCTVV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif INSM1 Original Motif Reverse Complement VVTCCCCCTVV MGCCCCCTGMCA MVYCCCCHKMCA Direction: Forward Position #: 1 Overlap #: 11 Alignment: VVTCCCCCTVV- MGCCCCCTGMCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif MZF1_5-13 Original Motif Reverse Complement MVYCCCCHKMCA BTHCCCCTYB HDYCCCCTBVCA Direction: Forward Position #: 1 Overlap #: 10 Alignment: MVYCCCCHKMCA BTHCCCCTYB-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccCCmCACCcc Reverse Complement Reverse Complement TGVVAGGGGMDH DDGGTGRGGBD KGGGWGGGGVDH Direction: Forward Position #: 1 Overlap #: 11 Alignment: TGVVAGGGGMDH DDGGTGRGGBD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Klf4 Original Motif Original Motif KGGGWGGGGVDH DGGGYGKGGC DGGGYGGGGHDH Direction: Forward Position #: 1 Overlap #: 10 Alignment: KGGGWGGGGVDH DGGGYGKGGC-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PLAG1 Reverse Complement Reverse Complement HHDCCCCMCCCD CCCCCTTGGGCCCC CCCCCTWVGSCCCCCCCD Direction: Forward Position #: 7 Overlap #: 8 Alignment: ------HHDCCCCMCCCD CCCCCTTGGGCCCC---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 24 Original Motif Reverse Complement CCCCCTWVGSCCCCCCCD TCCCAG YCCCMKWVGSCCCCCCCD Direction: Forward Position #: 1 Overlap #: 6 Alignment: CCCCCTWVGSCCCCCCCD TCCCAG------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- SP1 Combined Motif Original Motif Original Motif YCCCMKWVGSCCCCCCCD CCCCKCCCCC YCCCCCYBSCCCCCCCCD Direction: Forward Position #: 4 Overlap #: 10 Alignment: YCCCMKWVGSCCCCCCCD ---CCCCKCCCCC----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Original Motif Original Motif YCCCCCYBSCCCCCCCCD SSCGCCSCCGCCCSS YCCCVCCSCCBCCCCCCD Direction: Forward Position #: 2 Overlap #: 15 Alignment: YCCCCCYBSCCCCCCCCD -SSCGCCSCCGCCCSS-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RREB1 Combined Motif Reverse Complement Reverse Complement DGGGGGGBGGSGGVGGGM BGRRRGRGGRTGRTTYGGGG DGGBGGGDGGGGGTGGKHYGGGG Direction: Forward Position #: 4 Overlap #: 15 Alignment: DGGGGGGBGGSGGVGGGM----- ---BGRRRGRGGRTGRTTYGGGG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 40 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar REST Reverse Complement Reverse Complement VRVDGGHACAVDDKGTHCTDWH GGYGCTGTCCATGGTGCTGAA GVHGSTRYMCDDKGTBCTKAHV Direction: Backward Position #: 1 Overlap #: 21 Alignment: VRVDGGHACAVDDKGTHCTDWH -GGYGCTGTCCATGGTGCTGAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Reverse Complement Reverse Complement VHTYAGBACYDDGRKKASCDVC MSGKKRCGCWDCABTGBBCD MVKBDGCRCHDBRGKKHBCDVC Direction: Forward Position #: 1 Overlap #: 20 Alignment: VHTYAGBACYDDGRKKASCDVC MSGKKRCGCWDCABTGBBCD-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Original Motif Reverse Complement MVKBDGCRCHDBRGKKHBCDVC MGGTCAGGGTGACCTRDBHV MGGTCAGBDKSACCDVVVBBHBCDVC Direction: Forward Position #: 5 Overlap #: 16 Alignment: ----MVKBDGCRCHDBRGKKHBCDVC MGGTCAGGGTGACCTRDBHV------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RREB1 Combined Motif Reverse Complement Reverse Complement GVHGBHBVVVVDGGTSRHBCTGACCY BGRRRGRGGRTGRTTYGGGG GVHGBHVRVVGRGGDTGVYYTGRSVY Direction: Forward Position #: 6 Overlap #: 20 Alignment: GVHGBHBVVVVDGGTSRHBCTGACCY -----BGRRRGRGGRTGRTTYGGGG- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ryayAyAyrtGTRTrTry Combined Motif Original Motif Reverse Complement GVHGBHVRVVGRGGDTGVYYTGRSVY HDAMACACAKKTKTKTHD GVHGBHBAMAVAVRKKKDTKTVDSVY Direction: Forward Position #: 6 Overlap #: 18 Alignment: GVHGBHVRVVGRGGDTGVYYTGRSVY -----HDAMACACAKKTKTKTHD--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Original Motif Original Motif GVHGBHBAMAVAVRKKKDTKTVDSVY BTRGGDCARAGGKCA GVHGBHDRVDCAVRGKKBWKTVDSVY Direction: Forward Position #: 5 Overlap #: 15 Alignment: GVHGBHBAMAVAVRKKKDTKTVDSVY ----BTRGGDCARAGGKCA------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- yayAyAyACATrya Combined Motif Original Motif Reverse Complement GVHGBHDRVDCAVRGKKBWKTVDSVY DHKATGTKTKTGTD GVHGBHVKAHGWDDKTKBDKTVDSVY Direction: Forward Position #: 6 Overlap #: 14 Alignment: GVHGBHDRVDCAVRGKKBWKTVDSVY -----DHKATGTKTKTGTD------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Reverse Complement Reverse Complement MVSHVARDVYAYDHWCHTYBHBCDVC BAGGYCABHBTGACCKHV MVSHVARDHCAYDBTGAYCKHVCDVC Direction: Forward Position #: 5 Overlap #: 18 Alignment: MVSHVARDVYAYDHWCHTYBHBCDVC ----BAGGYCABHBTGACCKHV---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCwGGCCwGCss Combined Motif Reverse Complement Original Motif GVHGVHRGKTCABDKTGHHMTVDSVY BBCWGGCCAGCBB GVHVBCDGGYCAGCBBGHHMTVDSVY Direction: Forward Position #: 4 Overlap #: 13 Alignment: GVHGVHRGKTCABDKTGHHMTVDSVY ---BBCWGGCCAGCBB---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- HNF4A Combined Motif Reverse Complement Original Motif MVSHVARDHCVBGCTGKCCDGBVDVC RGGBCAAAGKYCA VGSBCARRGBHCDCTGKCCDGBVDVC Direction: Forward Position #: 1 Overlap #: 13 Alignment: MVSHVARDHCVBGCTGKCCDGBVDVC RGGBCAAAGKYCA------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 41 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Arnt Esrrb Original Motif Original Motif CACGTG CACGTG CACGTG Direction: Backward Position #: 1 Overlap #: 6 Alignment: CACGTG CACGTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif MYCMAX Reverse Complement Reverse Complement CACGTG ACCACGTGSTM ACCACGTGSTM Direction: Forward Position #: 3 Overlap #: 6 Alignment: --CACGTG--- ACCACGTGSTM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Myc Original Motif Reverse Complement ACCACGTGSTM DCCACGTGCV DCCACGTGSDM Direction: Forward Position #: 1 Overlap #: 10 Alignment: ACCACGTGSTM DCCACGTGCV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Mycn Original Motif Reverse Complement DCCACGTGSDM GCCACGTGSD DCCACGTGSDM Direction: Forward Position #: 1 Overlap #: 10 Alignment: DCCACGTGSDM GCCACGTGSD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif HIF1AARNT Reverse Complement Original Motif RHSCACGTGGH VBACGTGV VBRCRYGYGGH Direction: Forward Position #: 1 Overlap #: 8 Alignment: RHSCACGTGGH VBACGTGV--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ArntAhr Reverse Complement Reverse Complement DCCMCMMGKBV CACGCM CMCGCMMGKBV Direction: Forward Position #: 1 Overlap #: 6 Alignment: DCCMCMMGKBV CACGCM----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ZEB1 Combined Motif Reverse Complement Reverse Complement VBRCRYGCGYG HAGGTG VHASGTGCGYG Direction: Forward Position #: 2 Overlap #: 6 Alignment: VBRCRYGCGYG -HAGGTG---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Egr1 Original Motif Original Motif VHASGTGCGYG HGCGTGGGCGK HGCRBGKGCGBG Direction: Forward Position #: 2 Overlap #: 10 Alignment: -VHASGTGCGYG HGCGTGGGCGK- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ryayAyAyrtGTRTrTry Original Motif Original Motif HGCRBGKGCGBG DHAYAYAYRTGTGTRTDH DHRYRYRBGYGTGTRTDH Direction: Forward Position #: 2 Overlap #: 12 Alignment: -HGCRBGKGCGBG----- DHAYAYAYRTGTGTRTDH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif MIZF Reverse Complement Original Motif HDAMACACKCVKKKKKHD BAACGTCCGC HDACRYMCGCVKKKKKHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: HDAMACACKCVKKKKKHD BAACGTCCGC-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 42 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ArntAhr Egr1 Reverse Complement Reverse Complement CACGCM YCGCCCACGCH CACGCMYCGCC Direction: Backward Position #: 1 Overlap #: 6 Alignment: -----CACGCM YCGCCCACGCH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif HIF1AARNT Original Motif Reverse Complement CACGCMYCGCC VCACGTBV VCACGYHHCGCC Direction: Forward Position #: 2 Overlap #: 7 Alignment: -CACGCMYCGCC VCACGTBV---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 27 Original Motif Original Motif VCACGYHHCGCC CAYACACACACACA CAYACACACACRCAHCGCC Direction: Forward Position #: 8 Overlap #: 7 Alignment: -------VCACGYHHCGCC CAYACACACACACA----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Esrrb Original Motif Reverse Complement CAYACACACACRCAHCGCC CACGTG CACRYRCACACRCAHCGCC Direction: Forward Position #: 1 Overlap #: 6 Alignment: CAYACACACACRCAHCGCC CACGTG------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Arnt Original Motif Reverse Complement CACRYRCACACRCAHCGCC CACGTG CACGTRCACACRCAHCGCC Direction: Forward Position #: 1 Overlap #: 6 Alignment: CACRYRCACACRCAHCGCC CACGTG------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACACACACACA Original Motif Original Motif CACGTRCACACRCAHCGCC CACACACACACA CACRYACACACACAHCGCC Direction: Forward Position #: 1 Overlap #: 12 Alignment: CACGTRCACACRCAHCGCC CACACACACACA------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 25 Combined Motif Reverse Complement Reverse Complement GGCGDTGTGTGTGTKKGTG TGTGTGKVTGTGTG GGCKGTGTGTGTGTGTGTG Direction: Forward Position #: 4 Overlap #: 14 Alignment: GGCGDTGTGTGTGTKKGTG ---TGTGTGKVTGTGTG-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Reverse Complement Original Motif CACACACACACACACYGCC HVCATGCATGCABD CACAYRCAYRCACACYGCC Direction: Forward Position #: 1 Overlap #: 14 Alignment: CACACACACACACACYGCC HVCATGCATGCABD----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CACACACACACA Combined Motif Reverse Complement Reverse Complement GGCKGTGTGMMTGMMTGTG TGTGTGTGTGTG GGCTGTGTGYVTGHVTGTG Direction: Forward Position #: 4 Overlap #: 12 Alignment: GGCKGTGTGMMTGMMTGTG ---TGTGTGTGTGTG---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- MYCMAX Combined Motif Reverse Complement Original Motif CACAVHCAVMCACACAGCC RASCACGTGGT CAVVCACRYGGCCACAVHC Direction: Backward Position #: 2 Overlap #: 11 Alignment: CACAVHCAVMCACACAGCC -------RASCACGTGGT- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 43 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- E2F1 PLAG1 Original Motif Reverse Complement TTTSGCGC CCCCCTTGGGCCCC CYYYSKYGSGCCCC Direction: Forward Position #: 2 Overlap #: 8 Alignment: -TTTSGCGC----- CCCCCTTGGGCCCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PPARGRXRA Reverse Complement Original Motif GGGGCSCKYSKKMG BTRGGDCARAGGKCA BGRGGSSMRVGGKMR Direction: Forward Position #: 2 Overlap #: 14 Alignment: -GGGGCSCKYSKKMG BTRGGDCARAGGKCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif HNF4A Reverse Complement Reverse Complement MRRCCBMYSSCCMCB TGMYCTTTGBCCK HGRYCTHTGBCCBCB Direction: Forward Position #: 1 Overlap #: 13 Alignment: MRRCCBMYSSCCMCB TGMYCTTTGBCCK-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NR1H2RXRA Reverse Complement Original Motif BGBGGBCAHAGKKCH AAAGGTCAAAGGTCAAC VRRGGTCAAAGGTCAAC Direction: Forward Position #: 1 Overlap #: 15 Alignment: BGBGGBCAHAGKKCH-- AAAGGTCAAAGGTCAAC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR2F1 Combined Motif Original Motif Reverse Complement VRRGGTCAAAGGTCAAC AKGYYCAAAGRTCA VRDGBTCAAAGGTCAAC Direction: Forward Position #: 2 Overlap #: 14 Alignment: VRRGGTCAAAGGTCAAC -AKGYYCAAAGRTCA-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfp423 Combined Motif Reverse Complement Reverse Complement GTTGACCTTTGABCHKB GYRYCCMTKGGYRSC GTTGACCTDTGHCCMTKGGYRSC Direction: Forward Position #: 9 Overlap #: 9 Alignment: GTTGACCTTTGABCHKB------ --------GYRYCCMTKGGYRSC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- tyTCTkTkTCyy Combined Motif Original Motif Original Motif GTTGACCTDTGHCCMTKGGYRSC BBTCTKTKTCHB GTTGHYCTKTKTCCHTKGGYRSC Direction: Forward Position #: 4 Overlap #: 12 Alignment: GTTGACCTDTGHCCMTKGGYRSC ---BBTCTKTKTCHB-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif sssCGssGCsss Reverse Complement Original Motif GSMMCCRADGGAYAYAGMHCAAC SSSCGSSGCSSS SGSCVCCGMVGGAYAYAGMHCAAC Direction: Forward Position #: 2 Overlap #: 11 Alignment: -GSMMCCRADGGAYAYAGMHCAAC SSSCGSSGCSSS------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssGMsGRGCGss Combined Motif Original Motif Original Motif SGSCVCCGMVGGAYAYAGMHCAAC VVGCSGGGCGBB SGSCVSSGCSGGRCRBAGMHCAAC Direction: Forward Position #: 6 Overlap #: 12 Alignment: SGSCVCCGMVGGAYAYAGMHCAAC -----VVGCSGGGCGBB------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- aaACAAAACaa Combined Motif Original Motif Original Motif SGSCVSSGCSGGRCRBAGMHCAAC AAACAAAACAA SGSCVSSGCSGGRCRBAGMHHAACAAAACAA Direction: Forward Position #: 21 Overlap #: 4 Alignment: SGSCVSSGCSGGRCRBAGMHCAAC------- --------------------AAACAAAACAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 44 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Egr1 ssCrCYyYCGss Original Motif Reverse Complement HGCGTGGGCGK BBCGGKGGMGBB BGCGKGGGCGKB Direction: Forward Position #: 1 Overlap #: 11 Alignment: HGCGTGGGCGK- BBCGGKGGMGBB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Original Motif Reverse Complement BGCGKGGGCGKB SSGGGCGGSGGCGSS BGCGGGBGVGGGCGSS Direction: Forward Position #: 2 Overlap #: 11 Alignment: BGCGKGGGCGKB---- -SSGGGCGGSGGCGSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RREB1 Combined Motif Reverse Complement Original Motif SSCGCCCVCBCCCGCV CCCCMAAMCAMCCMCMMMCV CCCSMMMVCACCCVCHMMCV Direction: Forward Position #: 1 Overlap #: 16 Alignment: SSCGCCCVCBCCCGCV---- CCCCMAAMCAMCCMCMMMCV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACACACACACA Original Motif Original Motif CCCSMMMVCACCCVCHMMCV CACACACACACA CMCACACACACMCVCHMMCV Direction: Forward Position #: 1 Overlap #: 12 Alignment: CCCSMMMVCACCCVCHMMCV CACACACACACA-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACACACACACA Original Motif Original Motif CMCACACACACMCVCHMMCV CACACACACACA CACACACACACACVCHMMCV Direction: Forward Position #: 1 Overlap #: 12 Alignment: CMCACACACACMCVCHMMCV CACACACACACA-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 27 Original Motif Original Motif CACACACACACACVCHMMCV CAYACACACACACA CACACACACACACACHMMCV Direction: Forward Position #: 1 Overlap #: 14 Alignment: CACACACACACACVCHMMCV CAYACACACACACA------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccCCmCACCcc Original Motif Original Motif CACACACACACACACHMMCV HBCCMCACCHH HCMCMCACMCACACACHMMCV Direction: Forward Position #: 2 Overlap #: 10 Alignment: -CACACACACACACACHMMCV HBCCMCACCHH---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssGMsGRGCGss Combined Motif Original Motif Reverse Complement HCMCMCACMCACACACHMMCV BBCGCCCSGCVV HCMCVCMSCCMCRCVCHMMCV Direction: Forward Position #: 5 Overlap #: 12 Alignment: HCMCMCACMCACACACHMMCV ----BBCGCCCSGCVV----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 25 Original Motif Original Motif HCMCVCMSCCMCRCVCHMMCV CACACAVRCACACA CACACACACMCACACVCHMMCV Direction: Forward Position #: 2 Overlap #: 13 Alignment: -HCMCVCMSCCMCRCVCHMMCV CACACAVRCACACA-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Zfp423 Reverse Complement Reverse Complement BGRRDGBGTGTGYGTGTGTGTG GYRYCCMTKGGYRSC SCGYGYSCVTKKGYGBGRRDGBGT Direction: Backward Position #: 3 Overlap #: 13 Alignment: BGRRDGBGTGTGYGTGTGTGTG-- ---------GYRYCCMTKGGYRSC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 45 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Pax5 Reverse Complement Reverse Complement MGGTCAGGGTGACCTRDBHV MSGKKRCGCWDCABTGBBCD MGGTBAVGCTKVMCTGBBMD Direction: Backward Position #: 1 Overlap #: 20 Alignment: MGGTCAGGGTGACCTRDBHV MSGKKRCGCWDCABTGBBCD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Original Motif Reverse Complement MGGTBAVGCTKVMCTGBBMD VRVDGGHACAVDDKGTHCTDWH MGGTBRVDSKDACVBDBKGTHCTDWH Direction: Forward Position #: 5 Overlap #: 16 Alignment: MGGTBAVGCTKVMCTGBBMD------ ----VRVDGGHACAVDDKGTHCTDWH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RREB1 Reverse Complement Original Motif HWDAGHACRBHVBGTDYSHVKBACCY CCCCMAAMCAMCCMCMMMCV CCHCARAMCAHCMHSHVCSVVKBACCY Direction: Forward Position #: 2 Overlap #: 19 Alignment: -HWDAGHACRBHVBGTDYSHVKBACCY CCCCMAAMCAMCCMCMMMCV------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR2 Reverse Complement Reverse Complement MGGTBRVVSGBHSDRGDTGYTMTGDGG BAGGYCABHBTGACCKHV BMGGTCABVSTGACBKDDTGYTMTGDGG Direction: Forward Position #: 2 Overlap #: 17 Alignment: -MGGTBRVVSGBHSDRGDTGYTMTGDGG BAGGYCABHBTGACCKHV---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RXRRAR_DR5 Original Motif Reverse Complement BMGGTCABVSTGACBKDDTGYTMTGDGG TGACCTCKVVBTGAYCK TSASSTCDVVBTGACCKDDTGYTMTGDGG Direction: Forward Position #: 2 Overlap #: 16 Alignment: -BMGGTCABVSTGACBKDDTGYTMTGDGG TGACCTCKVVBTGAYCK------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- REST Combined Motif Reverse Complement Reverse Complement CCHCARAMCAHHYGGTCABVVDGASSTSA GGYGCTGTCCATGGTGCTGAA CCHCARAMCAHHYGGTCABGGHGMTGTCMATGGTGCTGAA Direction: Forward Position #: 20 Overlap #: 10 Alignment: CCHCARAMCAHHYGGTCABVVDGASSTSA----------- -------------------GGYGCTGTCCATGGTGCTGAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RXRAVDR Combined Motif Original Motif Original Motif CCHCARAMCAHHYGGTCABGGHGMTGTCMATGGTGCTGAA GGGTCAWBGRGTTCA CCHCARAMCAHHBGGTCAHVGDGYTSWCMATGGTGCTGAA Direction: Forward Position #: 13 Overlap #: 15 Alignment: CCHCARAMCAHHYGGTCABGGHGMTGTCMATGGTGCTGAA ------------GGGTCAWBGRGTTCA------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Original Motif Original Motif CCHCARAMCAHHBGGTCAHVGDGYTSWCMATGGTGCTGAA BTRGGDCARAGGKCA CCHVHRRVSMAVRGGTCAHVGDGYTSWCMATGGTGCTGAA Direction: Forward Position #: 4 Overlap #: 15 Alignment: CCHCARAMCAHHBGGTCAHVGDGYTSWCMATGGTGCTGAA ---BTRGGDCARAGGKCA---------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Reverse Complement Original Motif TTCAGCACCATRGWSAMCDCVHTGACCKBTYSVMMHVDGG SSCGCCSCCGCCCSS TTCAGCACCVBVGHSVMCDCCCBSACCKBTYSVMMHVDGG Direction: Forward Position #: 10 Overlap #: 15 Alignment: TTCAGCACCATRGWSAMCDCVHTGACCKBTYSVMMHVDGG ---------SSCGCCSCCGCCCSS---------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- AAAAAAAAAAA Combined Motif Reverse Complement Original Motif CCHVHRRVSMAVRGGTSVGGGHGRBSDCVBBGGTGCTGAA HVCATGCATGCABD ABVCATGSRTGCWGACCHVHRRVSMAVRGGTSVGGGHGRB Direction: Backward Position #: 2 Overlap #: 14 Alignment: CCHVHRRVSMAVRGGTSVGGGHGRBSDCVBBGGTGCTGAA -------------------------HVCATGCATGCABD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 46 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Ar Reverse Complement Original Motif BAGGYCABHBTGACCKHV HWDAGHACRHHVTGTHCCHVMV HWHAGDWCAHHVTGWCCBHVMV Direction: Forward Position #: 3 Overlap #: 18 Alignment: --BAGGYCABHBTGACCKHV-- HWDAGHACRHHVTGTHCCHVMV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Reverse Complement Original Motif VRVHBGGWCAVDDTGWHCTHWH DGVBCABTGDWGCGKRRCSR VRVHDGDDCAVBGDRKCSTVDCSR Direction: Forward Position #: 5 Overlap #: 18 Alignment: VRVHBGGWCAVDDTGWHCTHWH-- ----DGVBCABTGDWGCGKRRCSR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RREB1 Combined Motif Reverse Complement Original Motif MSGDBASGYMDCVVTGDHCHHVMV CCCCMAAMCAMCCMCMMMCV MSGDBMCVCMAMMCWVMMCCHVMCV Direction: Forward Position #: 6 Overlap #: 19 Alignment: MSGDBASGYMDCVVTGDHCHHVMV- -----CCCCMAAMCAMCCMCMMMCV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- REST Combined Motif Reverse Complement Reverse Complement BGRVDGGRRVWGYYTYGVGYVDCSR GGYGCTGTCCATGGTGCTGAA BGRVDGGVGCTGTCYHKGGTVCYGRA Direction: Forward Position #: 6 Overlap #: 20 Alignment: BGRVDGGRRVWGYYTYGVGYVDCSR- -----GGYGCTGTCCATGGTGCTGAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Reverse Complement Original Motif TKCMGVACCYDKGACAGCVCCHVMCB VDBHMAGGTCACCCTGACCY TKCMGVVCCHDGGHCASCVYSMCCBB Direction: Forward Position #: 6 Overlap #: 20 Alignment: TKCMGVACCYDKGACAGCVCCHVMCB -----VDBHMAGGTCACCCTGACCY- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RXRRAR_DR5 Combined Motif Reverse Complement Original Motif BBGGYSMVGSTGHCCDDGGBVCYGRA RGKTCABVVRGAGGTCA BRGGTCABVVWGASBTBRGBVCYGRA Direction: Forward Position #: 2 Overlap #: 17 Alignment: BBGGYSMVGSTGHCCDDGGBVCYGRA -RGKTCABVVRGAGGTCA-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Original Motif Original Motif BRGGTCABVVWGASBTBRGBVCYGRA BTRGGDCARAGGKCA BRGGTSHDGGDSAVVKGDSDVCYGRA Direction: Forward Position #: 6 Overlap #: 15 Alignment: BRGGTCABVVWGASBTBRGBVCYGRA -----BTRGGDCARAGGKCA------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Reverse Complement Original Motif TKCMGVDSDCYBVTSDCCHHSACCMB SSCGCCSCCGCCCSS TKCMVVCGVCCBCKCVCCVHSACCMB Direction: Forward Position #: 5 Overlap #: 15 Alignment: TKCMGVDSDCYBVTSDCCHHSACCMB ----SSCGCCSCCGCCCSS------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Zfx Reverse Complement Reverse Complement BRGGTSHVGGVGRGBGGVCGVVYGRA VAGGCCBBGGCVBB BAGGYCHBGGVSVSBGGVCGVVYGRA Direction: Forward Position #: 1 Overlap #: 14 Alignment: BRGGTSHVGGVGRGBGGVCGVVYGRA VAGGCCBBGGCVBB------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR2F1 Combined Motif Original Motif Original Motif BAGGYCHBGGVSVSBGGVCGVVYGRA TGAMCTTTGMMCYT BWGRCCTTKGVVVBBGGVCGVVYGRA Direction: Forward Position #: 2 Overlap #: 14 Alignment: BAGGYCHBGGVSVSBGGVCGVVYGRA -TGAMCTTTGMMCYT----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 47 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Esrrb Arnt Original Motif Original Motif CACGTG CACGTG CACGTG Direction: Forward Position #: 1 Overlap #: 6 Alignment: CACGTG CACGTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif MYCMAX Reverse Complement Reverse Complement CACGTG ACCACGTGSTM ACCACGTGSTM Direction: Forward Position #: 3 Overlap #: 6 Alignment: --CACGTG--- ACCACGTGSTM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Myc Original Motif Reverse Complement ACCACGTGSTM DCCACGTGCV DCCACGTGSDM Direction: Forward Position #: 1 Overlap #: 10 Alignment: ACCACGTGSTM DCCACGTGCV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Mycn Original Motif Reverse Complement DCCACGTGSDM GCCACGTGSD DCCACGTGSDM Direction: Forward Position #: 1 Overlap #: 10 Alignment: DCCACGTGSDM GCCACGTGSD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif HIF1AARNT Reverse Complement Original Motif RHSCACGTGGH VBACGTGV VBRCRYGYGGH Direction: Forward Position #: 1 Overlap #: 8 Alignment: RHSCACGTGGH VBACGTGV--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ArntAhr Reverse Complement Reverse Complement DCCMCMMGKBV CACGCM CMCGCMMGKBV Direction: Forward Position #: 1 Overlap #: 6 Alignment: DCCMCMMGKBV CACGCM----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ZEB1 Combined Motif Reverse Complement Reverse Complement VBRCRYGCGYG HAGGTG VHASGTGCGYG Direction: Forward Position #: 2 Overlap #: 6 Alignment: VBRCRYGCGYG -HAGGTG---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Egr1 Original Motif Original Motif VHASGTGCGYG HGCGTGGGCGK HGCRBGKGCGBG Direction: Forward Position #: 2 Overlap #: 10 Alignment: -VHASGTGCGYG HGCGTGGGCGK- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ryayAyAyrtGTRTrTry Original Motif Original Motif HGCRBGKGCGBG DHAYAYAYRTGTGTRTDH DHRYRYRBGYGTGTRTDH Direction: Forward Position #: 2 Overlap #: 12 Alignment: -HGCRBGKGCGBG----- DHAYAYAYRTGTGTRTDH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif MIZF Reverse Complement Original Motif HDAMACACKCVKKKKKHD BAACGTCCGC HDACRYMCGCVKKKKKHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: HDAMACACKCVKKKKKHD BAACGTCCGC-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 48 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- EWSR1-FLI1 NR1H2RXRA Original Motif Original Motif GGAAGGAAGGAAGGAAGG AAAGGTCAAAGGTCAAC TCAACRAAGGWMRRARGGGAAGG Direction: Backward Position #: 6 Overlap #: 12 Alignment: GGAAGGAAGGAAGGAAGG----- ------AAAGGTCAAAGGTCAAC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 26 Combined Motif Original Motif Reverse Complement TCAACRAAGGWMRRARGGGAAGG AAAAAAACAAARRA TMAAVAAAGRAARRARGGGAAGG Direction: Forward Position #: 2 Overlap #: 14 Alignment: TCAACRAAGGWMRRARGGGAAGG -AAAAAAACAAARRA-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RREB1 Combined Motif Original Motif Reverse Complement TMAAVAAAGRAARRARGGGAAGG BGRRRGRGGRTGRTTYGGGG TMAAVAAAGRHVRRARGGGAWGGTTYGGGG Direction: Forward Position #: 11 Overlap #: 13 Alignment: TMAAVAAAGRAARRARGGGAAGG------- ----------BGRRRGRGGRTGRTTYGGGG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- SP1 Combined Motif Reverse Complement Original Motif CCCCMAACCWTCCCMTMMBHKCTTTBTTRA CCCCKCCCCC CCCCMAMCCHKCCCCBMMBHKCTTTBTTRA Direction: Forward Position #: 7 Overlap #: 10 Alignment: CCCCMAACCWTCCCMTMMBHKCTTTBTTRA ------CCCCKCCCCC-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rrAGGGGGArr Combined Motif Original Motif Reverse Complement CCCCMAMCCHKCCCCBMMBHKCTTTBTTRA VVTCCCCCTVV CCCCMAMCYCCCCCYBMMBHKCTTTBTTRA Direction: Forward Position #: 7 Overlap #: 11 Alignment: CCCCMAMCCHKCCCCBMMBHKCTTTBTTRA ------VVTCCCCCTVV------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 13 Combined Motif Reverse Complement Original Motif TMAAVAAAGRHVRRBMGGGGGMGRTYGGGG GAGRCAGR TMRAGRMAGRHVRRBMGGGGGMGRTYGGGG Direction: Forward Position #: 3 Overlap #: 8 Alignment: TMAAVAAAGRHVRRBMGGGGGMGRTYGGGG --GAGRCAGR-------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 4 Reverse Complement Original Motif CCCCMAMCYCCCCCYBMMBHMCTRKCTMRA CYBCCTCC CCCCCWCCYCCCCCYBMMBHMCTRKCTMRA Direction: Forward Position #: 1 Overlap #: 8 Alignment: CCCCMAMCYCCCCCYBMMBHMCTRKCTMRA CYBCCTCC---------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- dwCTTTTCwy Combined Motif Reverse Complement Reverse Complement TMRAGRMAGRHVRRBMGGGGGMGGWGGGGG DHGAAAAGHD TVVRAAAAGDDVRRBMGGGGGMGGWGGGGG Direction: Forward Position #: 2 Overlap #: 10 Alignment: TMRAGRMAGRHVRRBMGGGGGMGGWGGGGG -DHGAAAAGHD------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 7 Combined Motif Original Motif Original Motif TVVRAAAAGDDVRRBMGGGGGMGGWGGGGG ASASAGAA TVVAVAVAGAAVRRBMGGGGGMGGWGGGGG Direction: Forward Position #: 4 Overlap #: 8 Alignment: TVVRAAAAGDDVRRBMGGGGGMGGWGGGGG ---ASASAGAA------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 9 Combined Motif Reverse Complement Reverse Complement CCCCCWCCYCCCCCYBMMBTTCTVTVTBVA WTCCCAGC CCCCMTCCCMGCCCYBMMBTTCTVTVTBVA Direction: Forward Position #: 5 Overlap #: 8 Alignment: CCCCCWCCYCCCCCYBMMBTTCTVTVTBVA ----WTCCCAGC------------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 49 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- HIF1AARNT Mycn Original Motif Reverse Complement VBACGTGV GCCACGTGSD DSCACGTGSG Direction: Backward Position #: 2 Overlap #: 8 Alignment: -VBACGTGV- GCCACGTGSD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Myc Reverse Complement Original Motif CSCACGTGSH VGCACGTGGH CSCACGTGGH Direction: Forward Position #: 1 Overlap #: 10 Alignment: CSCACGTGSH VGCACGTGGH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif MYCMAX Reverse Complement Reverse Complement DCCACGTGSG ACCACGTGSTM VCCACGTGSKM Direction: Forward Position #: 1 Overlap #: 10 Alignment: DCCACGTGSG- ACCACGTGSTM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif MIZF Reverse Complement Reverse Complement RRSCACGTGGB GCGGACGTTV GCGSACGTKGB Direction: Forward Position #: 1 Overlap #: 10 Alignment: RRSCACGTGGB GCGGACGTTV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Ar Reverse Complement Reverse Complement VCYACGTSCGC VRVDGGHACAVDDKGTHCTDWH VVHASGTVCVVDDKGTHCTDWH Direction: Forward Position #: 1 Overlap #: 11 Alignment: VCYACGTSCGC----------- VRVDGGHACAVDDKGTHCTDWH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yayAyAyACATrya Original Motif Original Motif VVHASGTVCVVDDKGTHCTDWH HACAYAYACATRHD HVYAYRYACAYRBDGTHCTDWH Direction: Forward Position #: 1 Overlap #: 14 Alignment: VVHASGTVCVVDDKGTHCTDWH HACAYAYACATRHD-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccCCAGTGCAbr Original Motif Original Motif HVYAYRYACAYRBDGTHCTDWH HVCCAGTGCABD HVCMHGTRCABDBDGTHCTDWH Direction: Forward Position #: 1 Overlap #: 12 Alignment: HVYAYRYACAYRBDGTHCTDWH HVCCAGTGCABD---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Pax5 Reverse Complement Original Motif HWDAGHACDVHVTGMACHRGBD DGVBCABTGDWGCGKRRCSR DDDDSAACDDHGYGHAVCVGBD Direction: Forward Position #: 1 Overlap #: 20 Alignment: HWDAGHACDVHVTGMACHRGBD DGVBCABTGDWGCGKRRCSR-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RREB1 Reverse Complement Original Motif HVCVGVTHCMCHDHGTTSDDHD CCCCMAAMCAMCCMCMMMCV CCCCVAHMCACCHMSHHCBHHD Direction: Forward Position #: 1 Overlap #: 20 Alignment: HVCVGVTHCMCHDHGTTSDDHD CCCCMAAMCAMCCMCMMMCV-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- AAAAAAAAAAA Combined Motif Reverse Complement Reverse Complement DDHBGDDSRDGGTGRHTBGGGG DVTGCATGCATGBH DDDVKGHVKGVRTGDHTBGGGG Direction: Forward Position #: 3 Overlap #: 14 Alignment: DDHBGDDSRDGGTGRHTBGGGG --DVTGCATGCATGBH------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 50 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- HNF4A PPARGRXRA Original Motif Original Motif RGGBCAAAGKYCA BTRGGDCARAGGKCA BTRGGBCAAAGGTCA Direction: Forward Position #: 3 Overlap #: 13 Alignment: --RGGBCAAAGKYCA BTRGGDCARAGGKCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NR2F1 Reverse Complement Original Motif TGACCTTTGBCCKAB TGAMCTTTGMMCYT TGACCTTTGVMCBHB Direction: Forward Position #: 1 Overlap #: 14 Alignment: TGACCTTTGBCCKAB TGAMCTTTGMMCYT- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NR1H2RXRA Reverse Complement Original Motif BHVGRVCAAAGGTCA AAAGGTCAAAGGTCAAC VAAGGTCAAAGGTCAAC Direction: Forward Position #: 1 Overlap #: 15 Alignment: BHVGRVCAAAGGTCA-- AAAGGTCAAAGGTCAAC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RXRRAR_DR5 Original Motif Original Motif VAAGGTCAAAGGTCAAC RGKTCABVVRGAGGTCA RGDTMRBBCARAGGTCAAC Direction: Forward Position #: 3 Overlap #: 15 Alignment: --VAAGGTCAAAGGTCAAC RGKTCABVVRGAGGTCA-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Pax5 Original Motif Original Motif RGDTMRBBCARAGGTCAAC DGVBCABTGDWGCGKRRCSR RGDDCRBBSAARSGTVAMSR Direction: Forward Position #: 1 Overlap #: 19 Alignment: RGDTMRBBCARAGGTCAAC- DGVBCABTGDWGCGKRRCSR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Reverse Complement Reverse Complement MSYTVACSMTTSVBKGDHCK BAGGYCABHBTGACCKHV MSYTVASGHHWBVBTGACCKHV Direction: Forward Position #: 5 Overlap #: 16 Alignment: MSYTVACSMTTSVBKGDHCK-- ----BAGGYCABHBTGACCKHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Reverse Complement Reverse Complement VHRGGTCABVBWDDCSTVAMSR VRVDGGHACAVDDKGTHCTDWH VDVGGKHACVVDDKGBTCDHHD Direction: Forward Position #: 1 Overlap #: 22 Alignment: VHRGGTCABVBWDDCSTVAMSR VRVDGGHACAVDDKGTHCTDWH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Reverse Complement Original Motif DDHDGAVCRHDVBGTDYCCBDV VDBHMAGGTCACCCTGACCY DVHDBMASGBVABSBTSMCBBV Direction: Forward Position #: 2 Overlap #: 20 Alignment: DDHDGAVCRHDVBGTDYCCBDV -VDBHMAGGTCACCCTGACCY- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PLAG1 Combined Motif Reverse Complement Reverse Complement VVBGRSAVSBTVVCSTYBHHVD CCCCCTTGGGCCCC VVBGRSAVSBTVVCCCCCBWVGGCCCC Direction: Forward Position #: 14 Overlap #: 9 Alignment: VVBGRSAVSBTVVCSTYBHHVD----- -------------CCCCCTTGGGCCCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yayAyAyACATrya Original Motif Reverse Complement VVBGRSAVSBTVVCCCCCBWVGGCCCC DHKATGTKTKTGTD DHBABGDBDDTKTBVCCCCCBWVGGCCCC Direction: Forward Position #: 3 Overlap #: 12 Alignment: --VVBGRSAVSBTVVCCCCCBWVGGCCCC DHKATGTKTKTGTD--------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 51 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- INSM1 PPARGRXRA Original Motif Original Motif TGYCAGGGGGCR BTRGGDCARAGGKCA BTRKGBCAGRGGKCA Direction: Forward Position #: 4 Overlap #: 12 Alignment: ---TGYCAGGGGGCR BTRGGDCARAGGKCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGCCsCCrCCCss Original Motif Reverse Complement BTRKGBCAGRGGKCA SSGGGCGGSGGCGSS SBGGGHSRGGGSGSV Direction: Forward Position #: 1 Overlap #: 15 Alignment: BTRKGBCAGRGGKCA SSGGGCGGSGGCGSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RREB1 Combined Motif Original Motif Reverse Complement SBGGGHSRGGGSGSV BGRRRGRGGRTGRTTYGGGG SBBGGVVRGGGGKGRTTYGGGG Direction: Forward Position #: 3 Overlap #: 13 Alignment: SBGGGHSRGGGSGSV------- --BGRRRGRGGRTGRTTYGGGG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Zfp423 Original Motif Original Motif SBBGGVVRGGGGKGRTTYGGGG GSMMCCYARGGKKKC GSVVSCBRRGGGKGVTTYGGGG Direction: Forward Position #: 1 Overlap #: 15 Alignment: SBBGGVVRGGGGKGRTTYGGGG GSMMCCYARGGKKKC------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif HNF4A Original Motif Original Motif GSVVSCBRRGGGKGVTTYGGGG RGGBCAAAGKYCA RGVVCMVAGGGBDGVTTYGGGG Direction: Forward Position #: 1 Overlap #: 13 Alignment: GSVVSCBRRGGGKGVTTYGGGG RGGBCAAAGKYCA--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssGMsGRGCGss Combined Motif Original Motif Original Motif RGVVCMVAGGGBDGVTTYGGGG VVGCSGGGCGBB RGVVSVGMGGGGHGVBTYGGGG Direction: Forward Position #: 5 Overlap #: 12 Alignment: RGVVCMVAGGGBDGVTTYGGGG ----VVGCSGGGCGBB------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Reverse Complement Reverse Complement CCCCMAVVCDCCCCYCBSVVCM MGGTCAGGGTGACCTRDBHV MVSYCAVVVYGVCCBBVBBVVCM Direction: Forward Position #: 2 Overlap #: 19 Alignment: -CCCCMAVVCDCCCCYCBSVVCM MGGTCAGGGTGACCTRDBHV--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CACACACACACA Combined Motif Original Motif Original Motif MVSYCAVVVYGVCCBBVBBVVCM CACACACACACA MVSYCAVVVYGVCCBBVBBCACACACACACA Direction: Forward Position #: 20 Overlap #: 4 Alignment: MVSYCAVVVYGVCCBBVBBVVCM-------- -------------------CACACACACACA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Original Motif Reverse Complement MVSYCAVVVYGVCCBBVBBCACACACACACA MSGKKRCGCWDCABTGBBCD MSGBCAMGCHKCMCHDBBMBACACACACACA Direction: Forward Position #: 1 Overlap #: 20 Alignment: MVSYCAVVVYGVCCBBVBBCACACACACACA MSGKKRCGCWDCABTGBBCD----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfx Combined Motif Reverse Complement Reverse Complement TGTGTGTGTGTBRVBHHGRGYHGCRTGVCSY VAGGCCBBGGCVBB TGTGTGWGKSCBBGSCVBVGYHGCRTGVCSY Direction: Forward Position #: 6 Overlap #: 14 Alignment: TGTGTGTGTGTBRVBHHGRGYHGCRTGVCSY -----VAGGCCBBGGCVBB------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 52 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Klf4 ccCCmCACCcc Original Motif Reverse Complement DGGGYGKGGC DDGGTGRGGBD DGGGTGGGGBD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DGGGYGKGGC- DDGGTGRGGBD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Reverse Complement Original Motif HBCCCCACCCH SSCGCCSCCGCCCSS HBCCVCMCCCDCCCSS Direction: Forward Position #: 2 Overlap #: 10 Alignment: HBCCCCACCCH----- -SSCGCCSCCGCCCSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RREB1 Original Motif Original Motif HBCCVCMCCCDCCCSS CCCCMAAMCAMCCMCMMMCV CCCCMMMCCMVCCCCVMMCV Direction: Forward Position #: 1 Overlap #: 16 Alignment: HBCCVCMCCCDCCCSS---- CCCCMAAMCAMCCMCMMMCV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfx Combined Motif Reverse Complement Original Motif BGRRVGGGGVYGGYRYGGGG BBVGCCBVGGCCTV BGRVVGGSSBHGGCCTGGGG Direction: Forward Position #: 4 Overlap #: 14 Alignment: BGRRVGGGGVYGGYRYGGGG ---BBVGCCBVGGCCTV--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCrCYyYCGss Combined Motif Original Motif Reverse Complement BGRVVGGSSBHGGCCTGGGG BBCGGKGGMGBB BGRVVSSGGDBGSSSBGGGG Direction: Forward Position #: 5 Overlap #: 12 Alignment: BGRVVGGSSBHGGCCTGGGG ----BBCGGKGGMGBB---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif SP1 Reverse Complement Original Motif CCCCVSSSCBHCCSSVVMCB CCCCKCCCCC CCCCDCCCCCHCCSSVVMCB Direction: Forward Position #: 1 Overlap #: 10 Alignment: CCCCVSSSCBHCCSSVVMCB CCCCKCCCCC---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 53 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- MIZF ssCrCYyYCGss Original Motif Original Motif BAACGTCCGC BBCRCCYCCGBB BBMACSTCCGCB Direction: Backward Position #: 2 Overlap #: 10 Alignment: -BAACGTCCGC- BBCRCCYCCGBB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif MYCMAX Original Motif Reverse Complement BBMACSTCCGCB ACCACGTGSTM VCCACGTSCKHB Direction: Forward Position #: 1 Overlap #: 11 Alignment: BBMACSTCCGCB ACCACGTGSTM- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Original Motif Reverse Complement VCCACGTSCKHB BAGGYCABHBTGACCKHV VCCASGTCMBHBTGACCKHV Direction: Forward Position #: 3 Overlap #: 10 Alignment: VCCACGTSCKHB-------- --BAGGYCABHBTGACCKHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Original Motif Original Motif VCCASGTCMBHBTGACCKHV VDBHMAGGTCACCCTGACCY VCCAVGBCMDBGTSACCBTGACCY Direction: Forward Position #: 5 Overlap #: 16 Alignment: VCCASGTCMBHBTGACCKHV---- ----VDBHMAGGTCACCCTGACCY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rmACAGCAGsr Reverse Complement Reverse Complement MGGTCAVGGTSACBDRGVCVTGGB DVCTGCTGTVB GTVBBDCTGCTMGGTCAVGGTSACBDRG Direction: Backward Position #: 5 Overlap #: 7 Alignment: MGGTCAVGGTSACBDRGVCVTGGB---- -----------------DVCTGCTGTVB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 54 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Myc Mycn Original Motif Original Motif VGCACGTGGH HSCACGTGGC VSCACGTGGC Direction: Backward Position #: 1 Overlap #: 10 Alignment: VGCACGTGGH HSCACGTGGC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif MYCMAX Reverse Complement Reverse Complement GCCACGTGSV ACCACGTGSTM DCCACGTGSDM Direction: Forward Position #: 1 Overlap #: 10 Alignment: GCCACGTGSV- ACCACGTGSTM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccCCAGTGCAbr Original Motif Original Motif DCCACGTGSDM HVCCAGTGCABD VCCMMGTGCAHD Direction: Forward Position #: 1 Overlap #: 11 Alignment: DCCACGTGSDM- HVCCAGTGCABD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGssCGss Original Motif Reverse Complement VCCMMGTGCAHD VSCGSSCGSB VBCGVGYGCVHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: VCCMMGTGCAHD VSCGSSCGSB-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif INSM1 Original Motif Reverse Complement VBCGVGYGCVHD MGCCCCCTGMCA MDCCCCSTGMCAD Direction: Forward Position #: 2 Overlap #: 11 Alignment: -VBCGVGYGCVHD MGCCCCCTGMCA- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGrGCGss Reverse Complement Reverse Complement DTGRCASGGGGHR VBCGCMCGSV BBCGCMCGSGGHR Direction: Forward Position #: 1 Overlap #: 10 Alignment: DTGRCASGGGGHR VBCGCMCGSV--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGCksCGss Original Motif Original Motif BBCGCMCGSGGHR VVCGCKSCGBB BBCGCHSSGSBHR Direction: Forward Position #: 1 Overlap #: 11 Alignment: BBCGCMCGSGGHR VVCGCKSCGBB-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Klf4 Original Motif Reverse Complement BBCGCHSSGSBHR GCCYCMCCCD BCCBCHCCSDBHR Direction: Forward Position #: 1 Overlap #: 10 Alignment: BBCGCHSSGSBHR GCCYCMCCCD--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCKCwsCGss Original Motif Original Motif BCCBCHCCSDBHR BVCGCWSCGBV BBCGCWCCGVBHR Direction: Forward Position #: 1 Overlap #: 11 Alignment: BCCBCHCCSDBHR BVCGCWSCGBV-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfx Combined Motif Reverse Complement Original Motif MDBVCGGWGCGBB BBVGCCBVGGCCTV MDBBSGSYGVGGCCTV Direction: Forward Position #: 3 Overlap #: 11 Alignment: MDBVCGGWGCGBB--- --BBVGCCBVGGCCTV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 55 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- MYCMAX RREB1 Reverse Complement Original Motif ACCACGTGSTM CCCCMAAMCAMCCMCMMMCV CCCCMMACSWSCHMCMMMCV Direction: Forward Position #: 4 Overlap #: 11 Alignment: ---ACCACGTGSTM------ CCCCMAAMCAMCCMCMMMCV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Original Motif Original Motif CCCCMMACSWSCHMCMMMCV HWDAGHACRHHVTGTHCCHVMV MHMMSMACVWVSYGYHCCVVMV Direction: Forward Position #: 1 Overlap #: 20 Alignment: CCCCMMACSWSCHMCMMMCV-- HWDAGHACRHHVTGTHCCHVMV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccCCAGTGCAbr Reverse Complement Original Motif VRBVGGHMCMSVWVGTYSYRDR HVCCAGTGCABD VDCCRGTVCAVVWVGTYSYRDR Direction: Forward Position #: 1 Overlap #: 12 Alignment: VRBVGGHMCMSVWVGTYSYRDR HVCCAGTGCABD---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Zfp423 Reverse Complement Reverse Complement MHMMSMACVWVVTGVACKGGHV GYRYCCMTKGGYRSC SCSVDHCYVHDSGBGMHMMSMACV Direction: Backward Position #: 3 Overlap #: 13 Alignment: MHMMSMACVWVVTGVACKGGHV-- ---------GYRYCCMTKGGYRSC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 56 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mycn Myc Original Motif Original Motif HSCACGTGGC VGCACGTGGH VSCACGTGGC Direction: Backward Position #: 1 Overlap #: 10 Alignment: HSCACGTGGC VGCACGTGGH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif MYCMAX Reverse Complement Reverse Complement GCCACGTGSV ACCACGTGSTM DCCACGTGSDM Direction: Forward Position #: 1 Overlap #: 10 Alignment: GCCACGTGSV- ACCACGTGSTM ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccCCAGTGCAbr Original Motif Original Motif DCCACGTGSDM HVCCAGTGCABD VCCMMGTGCAHD Direction: Forward Position #: 1 Overlap #: 11 Alignment: DCCACGTGSDM- HVCCAGTGCABD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGssCGss Original Motif Reverse Complement VCCMMGTGCAHD VSCGSSCGSB VBCGVGYGCVHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: VCCMMGTGCAHD VSCGSSCGSB-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGrGCGss Original Motif Original Motif VBCGVGYGCVHD VSCGRGCGBV VSCGVGCGSVHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: VBCGVGYGCVHD VSCGRGCGBV-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif INSM1 Original Motif Original Motif VSCGVGCGSVHD TGYCAGGGGGCR TGBVMGGGSGCRHD Direction: Forward Position #: 3 Overlap #: 10 Alignment: --VSCGVGCGSVHD TGYCAGGGGGCR-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGMsGRGCGss Original Motif Original Motif TGBVMGGGSGCRHD VVGCSGGGCGBB BGGCVGGGCGBVHD Direction: Forward Position #: 1 Overlap #: 12 Alignment: TGBVMGGGSGCRHD VVGCSGGGCGBB-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGCksCGss Reverse Complement Original Motif DDVBCGCCCVGCCV VVCGCKSCGBB BVCGCKCCSVGCCV Direction: Forward Position #: 1 Overlap #: 11 Alignment: DDVBCGCCCVGCCV VVCGCKSCGBB--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Klf4 Original Motif Reverse Complement BVCGCKCCSVGCCV GCCYCMCCCD BCCBCVCCCDGCCV Direction: Forward Position #: 1 Overlap #: 10 Alignment: BVCGCKCCSVGCCV GCCYCMCCCD---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Reverse Complement Original Motif BGGCHGGGVGBGGB VDBHMAGGTCACCCTGACCY BGBVVSSRGGBSRBCCTGACCY Direction: Forward Position #: 3 Overlap #: 12 Alignment: BGGCHGGGVGBGGB-------- --VDBHMAGGTCACCCTGACCY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 57 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- MZF1_5-13 rrAGGGGGArr Original Motif Original Motif BKAGGGGDAD VVAGGGGGAVV BDAGGGGGAVV Direction: Forward Position #: 1 Overlap #: 10 Alignment: BKAGGGGDAD- VVAGGGGGAVV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif INSM1 Reverse Complement Reverse Complement VBTCCCCCTHB MGCCCCCTGMCA MKYCCCCYKHCA Direction: Forward Position #: 1 Overlap #: 11 Alignment: VBTCCCCCTHB- MGCCCCCTGMCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Reverse Complement Original Motif TGDRKGGGGMYR DGVBCABTGDWGCGKRRCSR TGVDBRGKGAHGCGKRRCSR Direction: Forward Position #: 1 Overlap #: 12 Alignment: TGDRKGGGGMYR-------- DGVBCABTGDWGCGKRRCSR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PPARGRXRA Original Motif Reverse Complement TGVDBRGKGAHGCGKRRCSR TGRCCTKTGHCCKAB TGRBCKKTGVCSBRBRRCSR Direction: Forward Position #: 1 Overlap #: 15 Alignment: TGVDBRGKGAHGCGKRRCSR TGRCCTKTGHCCKAB----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfp423 Combined Motif Reverse Complement Original Motif MSGKKVMBSGBCAYRGBKCA GSMMCCYARGGKKKC MSGKGSMVCCYMRGGKKKCA Direction: Forward Position #: 5 Overlap #: 15 Alignment: MSGKKVMBSGBCAYRGBKCA ----GSMMCCYARGGKKKC- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RREB1 Combined Motif Reverse Complement Original Motif TGYYYCCKYKGGVRSCYCSR CCCCMAAMCAMCCMCMMMCV TGYCCCCHMDVSAVCCHCVVMCV Direction: Forward Position #: 4 Overlap #: 17 Alignment: TGYYYCCKYKGGVRSCYCSR--- ---CCCCMAAMCAMCCMCMMMCV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif HNF4A Reverse Complement Original Motif BGRBVGDGGBTSVDYHGGGGKCA RGGBCAAAGKYCA VGRBVRRRGKTSVDYHGGGGKCA Direction: Forward Position #: 1 Overlap #: 13 Alignment: BGRBVGDGGBTSVDYHGGGGKCA RGGBCAAAGKYCA---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RXRRAR_DR5 Reverse Complement Reverse Complement TGYCCCCHMDBSARCKKKVVMCV TGACCTCKVVBTGAYCK TGHCCYCDHVBKRACCKKVVMCV Direction: Forward Position #: 1 Overlap #: 17 Alignment: TGYCCCCHMDBSARCKKKVVMCV TGACCTCKVVBTGAYCK------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccCCmCACCcc Reverse Complement Reverse Complement VGRBVRRGGTMRVBDDGKGGHCA DDGGTGRGGBD DGGGTGRGGBVRVBDDGKGGHCA Direction: Forward Position #: 1 Overlap #: 11 Alignment: VGRBVRRGGTMRVBDDGKGGHCA DDGGTGRGGBD------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Original Motif Reverse Complement DGGGTGRGGBVRVBDDGKGGHCA SSGGGCGGSGGCGSS DGGGKGVGGBGRMGVVGKGGHCA Direction: Forward Position #: 2 Overlap #: 15 Alignment: DGGGTGRGGBVRVBDDGKGGHCA -SSGGGCGGSGGCGSS------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 58 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NFKB1 Tcfcp2l1 Original Motif Reverse Complement GGGGRTTCCCC CKGGDTBDMMCTGG TGGSGGGDTBBCCC Direction: Backward Position #: 4 Overlap #: 11 Alignment: GGGGRTTCCCC--- CKGGDTBDMMCTGG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGCTswGCCms Reverse Complement Original Motif GGGBVADCCCSCCA VBGCTSAGCCHB VGGSTVAGCCHSCCA Direction: Forward Position #: 2 Overlap #: 11 Alignment: -GGGBVADCCCSCCA VBGCTSAGCCHB--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Reverse Complement Original Motif TGGSDGGCTVASCCV TTCAGCACCATGGACAGCKCC TTCAGCACCATGGVSRGCDSMSCCV Direction: Forward Position #: 11 Overlap #: 11 Alignment: ----------TGGSDGGCTVASCCV TTCAGCACCATGGACAGCKCC---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGCCsCCrCCCss Reverse Complement Reverse Complement VGGSRSDGCKSBCCATGGTGCTGAA SSGGGCGGSGGCGSS BGGGGVGGCGGHSCVTGGTGCTGAA Direction: Forward Position #: 1 Overlap #: 15 Alignment: VGGSRSDGCKSBCCATGGTGCTGAA SSGGGCGGSGGCGSS---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Original Motif Reverse Complement BGGGGVGGCGGHSCVTGGTGCTGAA MSGKKRCGCWDCABTGBBCD VSGGKVVGCKBCVBHDGGYDCTGAA Direction: Forward Position #: 1 Overlap #: 20 Alignment: BGGGGVGGCGGHSCVTGGTGCTGAA MSGKKRCGCWDCABTGBBCD----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RREB1 Combined Motif Original Motif Reverse Complement VSGGKVVGCKBCVBHDGGYDCTGAA BGRRRGRGGRTGRTTYGGGG HSGDDRVGSRTGRYTTGGBGCTGAA Direction: Forward Position #: 1 Overlap #: 20 Alignment: VSGGKVVGCKBCVBHDGGYDCTGAA BGRRRGRGGRTGRTTYGGGG----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCwGGCCwGCss Reverse Complement Original Motif TTCAGCBCCAAMMCAMSCVMHHCSD BBCWGGCCAGCBB BBCWGSCCHGMVVCAMSCVMHHCSD Direction: Forward Position #: 1 Overlap #: 13 Alignment: TTCAGCBCCAAMMCAMSCVMHHCSD BBCWGGCCAGCBB------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Klf4 Reverse Complement Original Motif HSGDDRVGSRTGVBRCDGGSCWGVV DGGGYGKGGC DGGGBGDGGBTGVBRCDGGSCWGVV Direction: Forward Position #: 1 Overlap #: 10 Alignment: HSGDDRVGSRTGVBRCDGGSCWGVV DGGGYGKGGC--------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif mkARGCCACG Reverse Complement Original Motif BBCWGSCCHGMVVCABCCHCVCCCD CKAGGCCACG HKMRGCCMCGMVVCABCCHCVCCCD Direction: Forward Position #: 1 Overlap #: 10 Alignment: BBCWGSCCHGMVVCABCCHCVCCCD CKAGGCCACG--------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PLAG1 Combined Motif Reverse Complement Original Motif DGGGBGDGGBTGVBRCGYGGCKYRD GGGGCCCAAGGGGG DGGGBGGGGCYVDVGSGKGGCKYRD Direction: Forward Position #: 6 Overlap #: 14 Alignment: DGGGBGDGGBTGVBRCGYGGCKYRD -----GGGGCCCAAGGGGG------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 59 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR1H2RXRA REST Reverse Complement Reverse Complement GTTGACCTTTGACCTTT GGYGCTGTCCATGGTGCTGAA GGYGYTGWCCTTKGWSCTKWA Direction: Forward Position #: 4 Overlap #: 17 Alignment: ---GTTGACCTTTGACCTTT- GGYGCTGTCCATGGTGCTGAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PPARGRXRA Original Motif Reverse Complement GGYGYTGWCCTTKGWSCTKWA TGRCCTKTGHCCKAB TGRSCKYTGHCCTWBGWSCTKWA Direction: Forward Position #: 3 Overlap #: 13 Alignment: --GGYGYTGWCCTTKGWSCTKWA TGRCCTKTGHCCKAB-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RXRAVDR Original Motif Reverse Complement TGRSCKYTGHCCTWBGWSCTKWA TGAACKCBWTGACCC TGWRCBCBHTGACCHWBGWSCTKWA Direction: Forward Position #: 3 Overlap #: 13 Alignment: --TGRSCKYTGHCCTWBGWSCTKWA TGAACKCBWTGACCC---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Original Motif Reverse Complement TGWRCBCBHTGACCHWBGWSCTKWA MGGTCAGGGTGACCTRDBHV HGDDCDVBBTGACCHDBGHVCTKWA Direction: Forward Position #: 1 Overlap #: 20 Alignment: TGWRCBCBHTGACCHWBGWSCTKWA MGGTCAGGGTGACCTRDBHV----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 26 Combined Motif Original Motif Original Motif HGDDCDVBBTGACCHDBGHVCTKWA TKKTTTGTTTTTTT HGDDCDVBBTGACCHDTGDHYTKWDTTTTT Direction: Forward Position #: 17 Overlap #: 9 Alignment: HGDDCDVBBTGACCHDBGHVCTKWA----- ----------------TKKTTTGTTTTTTT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 60 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR4A2 NR1H2RXRA Original Motif Original Motif AAGGTCAC AAAGGTCAAAGGTCAAC AGGTCAACAAGGTCAMA Direction: Backward Position #: 9 Overlap #: 8 Alignment: -AAGGTCAC-------- AAAGGTCAAAGGTCAAC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Original Motif Reverse Complement AGGTCAACAAGGTCAMA MGGTCAGGGTGACCTRDBHV AGGTCARSRWGRYCWVVBHV Direction: Forward Position #: 1 Overlap #: 17 Alignment: AGGTCAACAAGGTCAMA--- MGGTCAGGGTGACCTRDBHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Reverse Complement Reverse Complement VDBBBWGKMCWKSKTGACCT BAGGYCABHBTGACCKHV VDBBBWGGHCABBBTGACCTHV Direction: Forward Position #: 5 Overlap #: 16 Alignment: VDBBBWGKMCWKSKTGACCT-- ----BAGGYCABHBTGACCKHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif mkARGCCACG Reverse Complement Original Motif VHAGGTCAVBVTGDCCWVVBHV CKAGGCCACG CDAGGYCAHGVTGDCCWVVBHV Direction: Forward Position #: 1 Overlap #: 10 Alignment: VHAGGTCAVBVTGDCCWVVBHV CKAGGCCACG------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Original Motif Reverse Complement CDAGGYCAHGVTGDCCWVVBHV VRVDGGHACAVDDKGTHCTDWH VDAGGBCACVVDGKSYWCDBHH Direction: Forward Position #: 1 Overlap #: 22 Alignment: CDAGGYCAHGVTGDCCWVVBHV VRVDGGHACAVDDKGTHCTDWH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PPARGRXRA Original Motif Original Motif VDAGGBCACVVDGKSYWCDBHH BTRGGDCARAGGKCA VDRGGBCAVAGKKBVYWCDBHH Direction: Forward Position #: 1 Overlap #: 15 Alignment: VDAGGBCACVVDGKSYWCDBHH BTRGGDCARAGGKCA------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccCCAGTGCAbr Original Motif Original Motif VDRGGBCAVAGKKBVYWCDBHH HVCCAGTGCABD HVCCAGKGCAVVGKKBVYWCDBHH Direction: Forward Position #: 3 Overlap #: 10 Alignment: --VDRGGBCAVAGKKBVYWCDBHH HVCCAGTGCABD------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR2F1 Combined Motif Original Motif Reverse Complement HVCCAGKGCAVVGKKBVYWCDBHH AKGYYCAAAGRTCA HVCVRGBKCAAAGRTCAYWCDBHH Direction: Forward Position #: 4 Overlap #: 14 Alignment: HVCCAGKGCAVVGKKBVYWCDBHH ---AKGYYCAAAGRTCA------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- REST Combined Motif Original Motif Original Motif HVCVRGBKCAAAGRTCAYWCDBHH TTCAGCACCATGGACAGCKCC HBYCAGBACMAHGGWCABHBBHHH Direction: Forward Position #: 2 Overlap #: 21 Alignment: HVCVRGBKCAAAGRTCAYWCDBHH -TTCAGCACCATGGACAGCKCC-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfx Combined Motif Original Motif Original Motif HBYCAGBACMAHGGWCABHBBHHH BBVGCCBVGGCCTV HBYCVGBRCCVVGGCCWBHBBHHH Direction: Forward Position #: 5 Overlap #: 14 Alignment: HBYCAGBACMAHGGWCABHBBHHH ----BBVGCCBVGGCCTV------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 61 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 ESR1 Reverse Complement Reverse Complement MSGKKRCGCWDCABTGBBCD MGGTCAGGGTGACCTRDBHV MGGTBAVGCTKVMCTGBBMD Direction: Backward Position #: 1 Overlap #: 20 Alignment: MSGKKRCGCWDCABTGBBCD MGGTCAGGGTGACCTRDBHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Original Motif Reverse Complement MGGTBAVGCTKVMCTGBBMD VRVDGGHACAVDDKGTHCTDWH MGGTBRVDSKDACVBDBKGTHCTDWH Direction: Forward Position #: 5 Overlap #: 16 Alignment: MGGTBAVGCTKVMCTGBBMD------ ----VRVDGGHACAVDDKGTHCTDWH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR2 Original Motif Reverse Complement MGGTBRVDSKDACVBDBKGTHCTDWH BAGGYCABHBTGACCKHV VVGKBMMBBBTRMCCKDBGTHCTDWH Direction: Forward Position #: 1 Overlap #: 18 Alignment: MGGTBRVDSKDACVBDBKGTHCTDWH BAGGYCABHBTGACCKHV-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Reverse Complement Original Motif HWDAGHACBDYGGYMABBBYRVYCBV TTCAGCACCATGGACAGCKCC HTHAGHACCDYGGHCAGBDBVVYCBV Direction: Forward Position #: 1 Overlap #: 21 Alignment: HWDAGHACBDYGGYMABBBYRVYCBV TTCAGCACCATGGACAGCKCC----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RXRRAR_DR5 Combined Motif Original Motif Original Motif HTHAGHACCDYGGHCAGBDBVVYCBV RGKTCABVVRGAGGTCA HTHAGGDYCAHGGASAGBTCAVYCBV Direction: Forward Position #: 5 Overlap #: 17 Alignment: HTHAGHACCDYGGHCAGBDBVVYCBV ----RGKTCABVVRGAGGTCA----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ryayAyAyrtGTRTrTry Combined Motif Original Motif Reverse Complement HTHAGGDYCAHGGASAGBTCAVYCBV HDAMACACAKKTKTKTHD HTHAGVDHCACRSABDKGTBDVBCBV Direction: Forward Position #: 6 Overlap #: 18 Alignment: HTHAGGDYCAHGGASAGBTCAVYCBV -----HDAMACACAKKTKTKTHD--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RREB1 Reverse Complement Reverse Complement VVGVBDBACRDBTSKGTGHHVCTDAH BGRRRGRGGRTGRTTYGGGG BGVRGRVRGRTGDYTBGGKGHHVCTDAH Direction: Forward Position #: 3 Overlap #: 18 Alignment: --VVGVBDBACRDBTSKGTGHHVCTDAH BGRRRGRGGRTGRTTYGGGG-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PPARGRXRA Original Motif Original Motif BGVRGRVRGRTGDYTBGGKGHHVCTDAH BTRGGDCARAGGKCA BBRGGVVARAKGKYWBGGKGHHVCTDAH Direction: Forward Position #: 1 Overlap #: 15 Alignment: BGVRGRVRGRTGDYTBGGKGHHVCTDAH BTRGGDCARAGGKCA------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Original Motif Reverse Complement BBRGGVVARAKGKYWBGGKGHHVCTDAH SSGGGCGGSGGCGSS BBVGGGGHGRSGGCGBGGKGHHVCTDAH Direction: Forward Position #: 3 Overlap #: 15 Alignment: BBRGGVVARAKGKYWBGGKGHHVCTDAH --SSGGGCGGSGGCGSS----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Original Motif Reverse Complement BBVGGGGHGRSGGCGBGGKGHHVCTDAH DVTGCATGCATGBH DVKGBRTGCMTGDHBBVGGGGHGRSGGC Direction: Backward Position #: 1 Overlap #: 14 Alignment: BBVGGGGHGRSGGCGBGGKGHHVCTDAH --------------DVTGCATGCATGBH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 62 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RORA_1 ESR1 Reverse Complement Reverse Complement TGACCTDVWT MGGTCAGGGTGACCTRDBHV VTGACCTDDDHMGGTCAGGG Direction: Backward Position #: 2 Overlap #: 10 Alignment: ---------TGACCTDVWT- MGGTCAGGGTGACCTRDBHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RXRAVDR Combined Motif Original Motif Reverse Complement VTGACCTDDDHMGGTCAGGG TGAACKCBWTGACCC VTGAMCKVDHTVRSYCAGGG Direction: Forward Position #: 2 Overlap #: 15 Alignment: VTGACCTDDDHMGGTCAGGG -TGAACKCBWTGACCC---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR1H2RXRA Combined Motif Reverse Complement Original Motif CCCTGKSKVAHHVRGYTCAV AAAGGTCAAAGGTCAAC CCCTGKSKVAHMRAGKTCAAAGGTCAAC Direction: Forward Position #: 12 Overlap #: 9 Alignment: CCCTGKSKVAHHVRGYTCAV-------- -----------AAAGGTCAAAGGTCAAC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RXRRAR_DR5 Reverse Complement Reverse Complement GTTGACCTTTGAYCTKYHTVRSYCAGGG TGACCTCKVVBTGAYCK TGVYYKAYCTBTGAYCKKYHTVRSYCAGGG Direction: Forward Position #: 3 Overlap #: 15 Alignment: --GTTGACCTTTGAYCTKYHTVRSYCAGGG TGACCTCKVVBTGAYCK------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR2F1 Combined Motif Original Motif Original Motif TGVYYKAYCTBTGAYCKKYHTVRSYCAGGG TGAMCTTTGMMCYT TGVYTGACCTTTGAHCBKYHTVRSYCAGGG Direction: Forward Position #: 5 Overlap #: 14 Alignment: TGVYYKAYCTBTGAYCKKYHTVRSYCAGGG ----TGAMCTTTGMMCYT------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Reverse Complement Original Motif CCCTGKSKVAHMRVGDTCAAAGGTCAMBCA BTRGGDCARAGGKCA CBBDGGSBAAARRDSATCAAAGGTCAMBCA Direction: Forward Position #: 2 Overlap #: 15 Alignment: CCCTGKSKVAHMRVGDTCAAAGGTCAMBCA -BTRGGDCARAGGKCA-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Original Motif Reverse Complement CBBDGGSBAAARRDSATCAAAGGTCAMBCA GGYGCTGTCCATGGTGCTGAA GSHBHKGTCMAWGGTGMTSAAAGGTCAMBCA Direction: Forward Position #: 2 Overlap #: 20 Alignment: -CBBDGGSBAAARRDSATCAAAGGTCAMBCA GGYGCTGTCCATGGTGCTGAA---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- HNF4A Combined Motif Original Motif Original Motif GSHBHKGTCMAWGGTGMTSAAAGGTCAMBCA RGGBCAAAGKYCA GSHBHDGKBCAARGKBCWSAAAGGTCAMBCA Direction: Forward Position #: 6 Overlap #: 13 Alignment: GSHBHKGTCMAWGGTGMTSAAAGGTCAMBCA -----RGGBCAAAGKYCA------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Reverse Complement Reverse Complement TGVYTGACCTTTSWGBRCKTTGBYCHDBDSC VRVDGGHACAVDDKGTHCTDWH DGVBKGAACHBTBDGTDCKTTDBYCHDBDSC Direction: Forward Position #: 1 Overlap #: 22 Alignment: TGVYTGACCTTTSWGBRCKTTGBYCHDBDSC VRVDGGHACAVDDKGTHCTDWH--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ccCCAGTGCAbr Combined Motif Reverse Complement Original Motif GSHBHDGKBHAARGDACDBAVHGTTCRVBCD HVCCAGTGCABD GSHBHDGBCCAGWGCACDBAVHGTTCRVBCD Direction: Forward Position #: 7 Overlap #: 12 Alignment: GSHBHDGKBHAARGDACDBAVHGTTCRVBCD ------HVCCAGTGCABD------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 63 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RXRRAR_DR5 ESR1 Original Motif Reverse Complement RGKTCABVVRGAGGTCA MGGTCAGGGTGACCTRDBHV DSRKSRTGRMCDGGBCAMGG Direction: Backward Position #: 1 Overlap #: 17 Alignment: ---RGKTCABVVRGAGGTCA MGGTCAGGGTGACCTRDBHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Reverse Complement Reverse Complement CCYTGVCCDGRKCAKSRKSD BAGGYCABHBTGACCKHV CCYTBABSHSABCVTGABCKHV Direction: Forward Position #: 5 Overlap #: 16 Alignment: CCYTGVCCDGRKCAKSRKSD-- ----BAGGYCABHBTGACCKHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Original Motif Reverse Complement CCYTBABSHSABCVTGABCKHV MSGKKRCGCWDCABTGBBCD CCBKBACGCHDBVVTGHBCDHV Direction: Forward Position #: 1 Overlap #: 20 Alignment: CCYTBABSHSABCVTGABCKHV MSGKKRCGCWDCABTGBBCD-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Original Motif Reverse Complement CCBKBACGCHDBVVTGHBCDHV VRVDGGHACAVDDKGTHCTDWH CCBKBRVVBGHHCVBGDBSTHCTDWH Direction: Forward Position #: 5 Overlap #: 18 Alignment: CCBKBACGCHDBVVTGHBCDHV---- ----VRVDGGHACAVDDKGTHCTDWH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Original Motif Original Motif CCBKBRVVBGHHCVBGDBSTHCTDWH BTRGGDCARAGGKCA CCBKBVBDGGDVMAAGGKSWHCTDWH Direction: Forward Position #: 6 Overlap #: 15 Alignment: CCBKBRVVBGHHCVBGDBSTHCTDWH -----BTRGGDCARAGGKCA------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RXRAVDR Combined Motif Original Motif Original Motif CCBKBVBDGGDVMAAGGKSWHCTDWH GGGTCAWBGRGTTCA TDWHRGGTCAHVGRGTTYVCCBKBVB Direction: Backward Position #: 5 Overlap #: 15 Alignment: CCBKBVBDGGDVMAAGGKSWHCTDWH -------GGGTCAWBGRGTTCA---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR2F1 Combined Motif Original Motif Reverse Complement TDWHRGGTCAHVGRGTTYVCCBKBVB AKGYYCAAAGRTCA TDWHRGBTCAAAGRKCWYVCCBKBVB Direction: Forward Position #: 4 Overlap #: 14 Alignment: TDWHRGGTCAHVGRGTTYVCCBKBVB ---AKGYYCAAAGRTCA--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PLAG1 Combined Motif Original Motif Original Motif TDWHRGBTCAAAGRKCWYVCCBKBVB GGGGCCCAAGGGGG TDGVGGSYCAARGGKSWYVCCBKBVB Direction: Forward Position #: 3 Overlap #: 14 Alignment: TDWHRGBTCAAAGRKCWYVCCBKBVB --GGGGCCCAAGGGGG---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- HNF4A Combined Motif Original Motif Original Motif TDGVGGSYCAARGGKSWYVCCBKBVB RGGBCAAAGKYCA TDGRGGBCMAAGGBBVWYVCCBKBVB Direction: Forward Position #: 4 Overlap #: 13 Alignment: TDGVGGSYCAARGGKSWYVCCBKBVB ---RGGBCAAAGKYCA---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RREB1 Combined Motif Original Motif Reverse Complement TDGRGGBCMAAGGBBVWYVCCBKBVB BGRRRGRGGRTGRTTYGGGG TDGRGGBCMAAGBGVVDVRVSGTGRYTYGGGG Direction: Forward Position #: 13 Overlap #: 14 Alignment: TDGRGGBCMAAGGBBVWYVCCBKBVB------ ------------BGRRRGRGGRTGRTTYGGGG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 64 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Tcfcp2l1 Ar Original Motif Original Motif CCAGYYHVADCCRG HWDAGHACRHHVTGTHCCHVMV MVMCAGYBYGWDCCDGHWDAGH Direction: Backward Position #: 3 Overlap #: 14 Alignment: ------CCAGYYHVADCCRG-- HWDAGHACRHHVTGTHCCHVMV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Original Motif Reverse Complement MVMCAGYBYGWDCCDGHWDAGH MGGTCAGGGTGACCTRDBHV MVVYMRBBBKDACCDGDDHVGH Direction: Forward Position #: 1 Overlap #: 20 Alignment: MVMCAGYBYGWDCCDGHWDAGH MGGTCAGGGTGACCTRDBHV-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfx Combined Motif Reverse Complement Original Motif HCBHDHCDGGTHRBBBKRKVVY BBVGCCBVGGCCTV BCBDBCBVGGCCTBBBKRKVVY Direction: Forward Position #: 1 Overlap #: 14 Alignment: HCBHDHCDGGTHRBBBKRKVVY BBVGCCBVGGCCTV-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RREB1 Original Motif Reverse Complement BCBDBCBVGGCCTBBBKRKVVY BGRRRGRGGRTGRTTYGGGG BSDDVVVRGGTSDBYYGRGVVY Direction: Forward Position #: 1 Overlap #: 20 Alignment: BCBDBCBVGGCCTBBBKRKVVY BGRRRGRGGRTGRTTYGGGG-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Reverse Complement Original Motif MVVCMCMMVHSACCMVVVHHSV SSCGCCSCCGCCCSS MVSCCVCCVCCVCCCVVVHHSV Direction: Forward Position #: 3 Overlap #: 15 Alignment: MVVCMCMMVHSACCMVVVHHSV --SSCGCCSCCGCCCSS----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PLAG1 Original Motif Reverse Complement MVSCCVCCVCCVCCCVVVHHSV CCCCCTTGGGCCCC CCCCCBHVGSCCCCCVVVHHSV Direction: Forward Position #: 1 Overlap #: 14 Alignment: MVSCCVCCVCCVCCCVVVHHSV CCCCCTTGGGCCCC-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR2 Combined Motif Reverse Complement Reverse Complement BSDDVVVGGGGGSCVHVGGGGG BAGGYCABHBTGACCKHV BVGGHSVVGGKGVCCDHGGGGG Direction: Forward Position #: 1 Overlap #: 18 Alignment: BSDDVVVGGGGGSCVHVGGGGG BAGGYCABHBTGACCKHV---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Reverse Complement Reverse Complement CCCCCHDGGBCRCCVBSHCCBB TGRCCTKTGHCCKAB YSVCCTDKGBCVBVBBSHCCBB Direction: Forward Position #: 1 Overlap #: 15 Alignment: CCCCCHDGGBCRCCVBSHCCBB TGRCCTKTGHCCKAB------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Reverse Complement Original Motif BVGGHSVBVBVGVCRDAGGVSM DGVBCABTGDWGCGKRRCSR DRVGHVVBGDDGMSDRRSGRSM Direction: Forward Position #: 1 Overlap #: 20 Alignment: BVGGHSVBVBVGVCRDAGGVSM DGVBCABTGDWGCGKRRCSR-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RXRRAR_DR5 Reverse Complement Reverse Complement YSMCSKKDSRCDDCVBBDCVMH TGACCTCKVVBTGAYCK TBVCCBBKVSDYGACCKBDCVMH Direction: Forward Position #: 2 Overlap #: 16 Alignment: -YSMCSKKDSRCDDCVBBDCVMH TGACCTCKVVBTGAYCK------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 65 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGrGCGss ssCGssCGss Reverse Complement Reverse Complement VBCGCMCGSV VSCGSSCGSB VBCGSVCGSV Direction: Forward Position #: 1 Overlap #: 10 Alignment: VBCGCMCGSV VSCGSSCGSB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGGsYCGss Reverse Complement Reverse Complement VSCGVSCGBV VSCGGSCCGSB VSCGGSCSGSB Direction: Forward Position #: 1 Overlap #: 10 Alignment: VSCGVSCGBV- VSCGGSCCGSB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCrCYyYCGss Original Motif Reverse Complement VSCGGSCSGSB BBCGGKGGMGBB VSCGGGSGSGBB Direction: Forward Position #: 1 Overlap #: 11 Alignment: VSCGGSCSGSB- BBCGGKGGMGBB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGsCwsCss Original Motif Original Motif VSCGGGSGSGBB BBCGSCWSCBB BVCGGCHGCGBB Direction: Forward Position #: 1 Overlap #: 11 Alignment: VSCGGGSGSGBB BBCGSCWSCBB- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGMsGRGCGss Original Motif Reverse Complement BVCGGCHGCGBB BBCGCCCSGCVV BBCGCCHSSCBV Direction: Forward Position #: 1 Overlap #: 12 Alignment: BVCGGCHGCGBB BBCGCCCSGCVV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGCksCGss Original Motif Original Motif BBCGCCHSSCBV VVCGCKSCGBB VVCGCBSCGSBV Direction: Forward Position #: 1 Overlap #: 11 Alignment: BBCGCCHSSCBV VVCGCKSCGBB- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGsCTCss Original Motif Original Motif VVCGCBSCGSBV VVCGSCTCBB VVCGCCTCGSBV Direction: Forward Position #: 1 Overlap #: 10 Alignment: VVCGCBSCGSBV VVCGSCTCBB-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Reverse Complement Reverse Complement VBSCGAGGCGVV SSGGGCGGSGGCGSS VBSSGRGSSGSGGCGSS Direction: Forward Position #: 3 Overlap #: 10 Alignment: VBSCGAGGCGVV----- --SSGGGCGGSGGCGSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCKCwsCGss Combined Motif Reverse Complement Original Motif SSCGCCSCSSCMCSSBV BVCGCWSCGBV SSCGSCGCBSCGCVSBV Direction: Forward Position #: 4 Overlap #: 11 Alignment: SSCGCCSCSSCMCSSBV ---BVCGCWSCGBV--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif sssCGssGCsss Original Motif Reverse Complement SSCGSCGCBSCGCVSBV SSSGCSSCGSSS SSSGCSSCGCBSCGCVSBV Direction: Forward Position #: 3 Overlap #: 10 Alignment: --SSCGSCGCBSCGCVSBV SSSGCSSCGSSS------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 66 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGssCGss ssCGrGCGss Reverse Complement Reverse Complement VSCGSSCGSB VBCGCMCGSV VBCGSVCGSV Direction: Forward Position #: 1 Overlap #: 10 Alignment: VSCGSSCGSB VBCGCMCGSV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGGsYCGss Reverse Complement Reverse Complement VSCGVSCGBV VSCGGSCCGSB VSCGGSCSGSB Direction: Forward Position #: 1 Overlap #: 10 Alignment: VSCGVSCGBV- VSCGGSCCGSB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- sssCGssGCsss Combined Motif Reverse Complement Original Motif BSCSGSCCGSV SSSCGSSGCSSS BSSSSGCCGCSSS Direction: Forward Position #: 2 Overlap #: 10 Alignment: BSCSGSCCGSV-- -SSSCGSSGCSSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGsCwsCss Original Motif Reverse Complement BSSSSGCCGCSSS BBGSWGSCGBB BBGSVGSCGSBSS Direction: Forward Position #: 1 Overlap #: 11 Alignment: BSSSSGCCGCSSS BBGSWGSCGBB-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCrCYyYCGss Reverse Complement Original Motif SSBSCGSCBSCBB BBCRCCYCCGBB SBCGCSBCCGCBB Direction: Forward Position #: 1 Overlap #: 12 Alignment: SSBSCGSCBSCBB BBCRCCYCCGBB- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGsCTCss Original Motif Original Motif SBCGCSBCCGCBB VVCGSCTCBB BBCGCCTCBGCBB Direction: Forward Position #: 1 Overlap #: 10 Alignment: SBCGCSBCCGCBB VVCGSCTCBB--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGCksCGss Original Motif Original Motif BBCGCCTCBGCBB VVCGCKSCGBB VVCGCBBCGSSBB Direction: Forward Position #: 1 Overlap #: 11 Alignment: BBCGCCTCBGCBB VVCGCKSCGBB-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Reverse Complement Reverse Complement BBSSCGBBGCGVV SSGGGCGGSGGCGSS BBSSSGGBGSGGGCGSS Direction: Forward Position #: 3 Overlap #: 11 Alignment: BBSSCGBBGCGVV---- --SSGGGCGGSGGCGSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssGMsGRGCGss Combined Motif Original Motif Original Motif BBSSSGGBGSGGGCGSS VVGCSGGGCGBB BVVGCGGVGCGSSCGSS Direction: Forward Position #: 2 Overlap #: 12 Alignment: BBSSSGGBGSGGGCGSS -VVGCSGGGCGBB---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Mycn Original Motif Original Motif BVVGCGGVGCGSSCGSS HSCACGTGGC VSCRCGKGGCGSSCGSS Direction: Forward Position #: 1 Overlap #: 10 Alignment: BVVGCGGVGCGSSCGSS HSCACGTGGC------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 67 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssGMsGRGCGss ssCrCYyYCGss Original Motif Reverse Complement VVGCSGGGCGBB BBCGGKGGMGBB VVSSGGGGCGBB Direction: Forward Position #: 1 Overlap #: 12 Alignment: VVGCSGGGCGBB BBCGGKGGMGBB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif sssCGssGCsss Original Motif Original Motif VVSSGGGGCGBB SSSCGSSGCSSS VSSCGSSGCGBS Direction: Forward Position #: 1 Overlap #: 12 Alignment: VVSSGGGGCGBB SSSCGSSGCSSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGCTswGCCms Original Motif Original Motif VSSCGSSGCGBS VBGCTSAGCCHB VBGCKSDGCSVB Direction: Forward Position #: 1 Overlap #: 12 Alignment: VSSCGSSGCGBS VBGCTSAGCCHB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfx Combined Motif Original Motif Original Motif VBGCKSDGCSVB BBVGCCBVGGCCTV VBSCKSBGCGGCCTV Direction: Forward Position #: 2 Overlap #: 11 Alignment: VBGCKSDGCSVB--- -BBVGCCBVGGCCTV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Reverse Complement Reverse Complement VAGGCCGCBSYGSBV SSGGGCGGSGGCGSS VAGGSSGCGGSGSCGSS Direction: Forward Position #: 3 Overlap #: 13 Alignment: VAGGCCGCBSYGSBV-- --SSGGGCGGSGGCGSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Original Motif Original Motif VAGGSSGCGGSGSCGSS DGVBCABTGDWGCGKRRCSR VAGDGVGCVVBGVHGSGKRRCSR Direction: Forward Position #: 4 Overlap #: 14 Alignment: VAGGSSGCGGSGSCGSS------ ---DGVBCABTGDWGCGKRRCSR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ccCCAGTGCAbr Combined Motif Reverse Complement Reverse Complement MSGKKRCSCHVCVVVGCVCHCTV DBTGCACTGGVD MSGBTGCACTGSVVVGCVCHCTV Direction: Forward Position #: 3 Overlap #: 12 Alignment: MSGKKRCSCHVCVVVGCVCHCTV --DBTGCACTGGVD--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Original Motif Reverse Complement MSGBTGCACTGSVVVGCVCHCTV MGGTCAGGGTGACCTRDBHV MGGBYRSVSTGVCCHGBVVVCTV Direction: Forward Position #: 1 Overlap #: 20 Alignment: MSGBTGCACTGSVVVGCVCHCTV MGGTCAGGGTGACCTRDBHV--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RREB1 Combined Motif Reverse Complement Original Motif VAGVVVBCHGGVCASVSKKVCCY CCCCMAAMCAMCCMCMMMCV VAGVVCCCMRVMCAVCCHBMCCCV Direction: Forward Position #: 5 Overlap #: 19 Alignment: VAGVVVBCHGGVCASVSKKVCCY- ----CCCCMAAMCAMCCMCMMMCV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCwGGCCwGCss Original Motif Original Motif VAGVVCCCMRVMCAVCCHBMCCCV BBCWGGCCAGCBB BBCAGGCCHSMVVMCAVCCHBMCCCV Direction: Forward Position #: 3 Overlap #: 11 Alignment: --VAGVVCCCMRVMCAVCCHBMCCCV BBCWGGCCAGCBB------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 68 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- dwCTTTTCwy wyATTTTAww Reverse Complement Reverse Complement DHGAAAAGHD DDTAAAATHD DHKAAAAKHD Direction: Backward Position #: 1 Overlap #: 10 Alignment: DHGAAAAGHD DDTAAAATHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTAAwAAww Original Motif Original Motif DHKAAAAKHD DDTAAWAAHH DHTAAAADHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DHKAAAAKHD DDTAAWAAHH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwWAAAAAwa Original Motif Original Motif DHTAAAADHD WWAAAAAAWH DWWAAAAAHH Direction: Forward Position #: 1 Overlap #: 10 Alignment: DHTAAAADHD WWAAAAAAWH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTAAAwAww Reverse Complement Reverse Complement HHTTTTTWWD HHTWTTTADD HHTTTTTADD Direction: Forward Position #: 1 Overlap #: 10 Alignment: HHTTTTTWWD HHTWTTTADD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtATTTTTAww Reverse Complement Reverse Complement DDTAAAAAHH DDTAAAAATHD DDTAAAAATHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DDTAAAAAHH- DDTAAAAATHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 69 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- aaACAAAACaa aaCAAAAACaa Reverse Complement Reverse Complement TTGTTTTGTTT HTGTTTTTGHH TTGTTTTKKTT Direction: Backward Position #: 1 Overlap #: 11 Alignment: TTGTTTTGTTT HTGTTTTTGHH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Original Motif Reverse Complement TTGTTTTKKTT TTTTTTTTTTT TTKTTTTTTTT Direction: Forward Position #: 1 Overlap #: 11 Alignment: TTGTTTTKKTT TTTTTTTTTTT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 26 Combined Motif Original Motif Original Motif TTKTTTTTTTT TKKTTTGTTTTTTT TTKTTTTKTTTTTTT Direction: Forward Position #: 2 Overlap #: 10 Alignment: TTKTTTTTTTT---- -TKKTTTGTTTTTTT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wtATTTTTAww Combined Motif Original Motif Original Motif TTKTTTTKTTTTTTT DHATTTTTADD TTDTWTTTTTWTTTT Direction: Forward Position #: 3 Overlap #: 11 Alignment: TTKTTTTKTTTTTTT --DHATTTTTADD-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rmACAGCAGsr Combined Motif Reverse Complement Original Motif AAAAWAAAAAWADAA VVACAGCAGVD AAAAWAAAAAWVVAMAGCAGVD Direction: Forward Position #: 12 Overlap #: 4 Alignment: AAAAWAAAAAWADAA------- -----------VVACAGCAGVD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RREB1 Combined Motif Original Motif Reverse Complement AAAAWAAAAAWVVAMAGCAGVD BGRRRGRGGRTGRTTYGGGG AAAAWAAAAAWVVAMAGCAGVDRGRGGRTGRTTYGGGG Direction: Forward Position #: 19 Overlap #: 4 Alignment: AAAAWAAAAAWVVAMAGCAGVD---------------- ------------------BGRRRGRGGRTGRTTYGGGG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif tyTCTkTkTCyy Original Motif Reverse Complement AAAAWAAAAAWVVAMAGCAGVDRGRGGRTGRTTYGGGG VHGARAYAGAVV AARADAHARAWVVAMAGCAGVDRGRGGRTGRTTYGGGG Direction: Forward Position #: 1 Overlap #: 12 Alignment: AAAAWAAAAAWVVAMAGCAGVDRGRGGRTGRTTYGGGG VHGARAYAGAVV-------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yayAyAyACATrya Original Motif Original Motif AARADAHARAWVVAMAGCAGVDRGRGGRTGRTTYGGGG HACAYAYACATRHD HABAHAYAVATRHAMAGCAGVDRGRGGRTGRTTYGGGG Direction: Forward Position #: 1 Overlap #: 14 Alignment: AARADAHARAWVVAMAGCAGVDRGRGGRTGRTTYGGGG HACAYAYACATRHD------------------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ryayAyAyrtGTRTrTry Original Motif Original Motif HABAHAYAVATRHAMAGCAGVDRGRGGRTGRTTYGGGG DHAYAYAYRTGTGTRTDH DHAYAYAYABRTRTRYAGCAGVDRGRGGRTGRTTYGGGG Direction: Forward Position #: 2 Overlap #: 17 Alignment: -HABAHAYAVATRHAMAGCAGVDRGRGGRTGRTTYGGGG DHAYAYAYRTGTGTRTDH--------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CACACACACACA Combined Motif Reverse Complement Original Motif CCCCMAAMCAMCCMCMHVCTGCTKKAMAKVTKTKTKTHD CACACACACACA CCCCMAAMCACMCACACACWGCTKKAMAKVTKTKTKTHD Direction: Forward Position #: 9 Overlap #: 12 Alignment: CCCCMAAMCAMCCMCMHVCTGCTKKAMAKVTKTKTKTHD --------CACACACACACA------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 70 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- mkARGCCACG ESR2 Reverse Complement Reverse Complement CGTGGCCTYG BAGGYCABHBTGACCKHV BAGGYCABCGTGRCCTYG Direction: Forward Position #: 9 Overlap #: 10 Alignment: --------CGTGGCCTYG BAGGYCABHBTGACCKHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Reverse Complement Original Motif CMAGGMCACGBTGMCCTB VDBHMAGGTCACCCTGACCY CMAGGVCAVGGTSACCYTGACCY Direction: Forward Position #: 4 Overlap #: 15 Alignment: CMAGGMCACGBTGMCCTB----- ---VDBHMAGGTCACCCTGACCY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR1H2RXRA Combined Motif Reverse Complement Reverse Complement MGGTCAKGGTSACCBTGVCCTYG GTTGACCTTTGACCTTT MGGTCAKGGTSACSTTGACCTTTGACCTTT Direction: Forward Position #: 14 Overlap #: 10 Alignment: MGGTCAKGGTSACCBTGVCCTYG------- -------------GTTGACCTTTGACCTTT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Reverse Complement Original Motif AAAGGTCAAAGGTCAASGTSACCYTGACCY BTRGGDCARAGGKCA AAAGGTCDARGGBMAAGGTSACCYTGACCY Direction: Forward Position #: 7 Overlap #: 15 Alignment: AAAGGTCAAAGGTCAASGTSACCYTGACCY ------BTRGGDCARAGGKCA--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Ar Reverse Complement Reverse Complement MGGTCAKGGTSACCTTYBCCKTDGACCTTT VRVDGGHACAVDDKGTHCTDWH VRVDVGDWCABGKTGWYCTTHBCCKTDGACCTTT Direction: Forward Position #: 5 Overlap #: 18 Alignment: ----MGGTCAKGGTSACCTTYBCCKTDGACCTTT VRVDGGHACAVDDKGTHCTDWH------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PLAG1 Combined Motif Reverse Complement Original Motif AAAGGTCDARGGVHAAGKWCAYCBTGWHCVHVMV GGGGCCCAAGGGGG ARRGGYCHARGGGDRAGKWCAYCBTGWHCVHVMV Direction: Forward Position #: 2 Overlap #: 14 Alignment: AAAGGTCDARGGVHAAGKWCAYCBTGWHCVHVMV -GGGGCCCAAGGGGG------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RREB1 Combined Motif Original Motif Reverse Complement ARRGGYCHARGGGDRAGKWCAYCBTGWHCVHVMV BGRRRGRGGRTGRTTYGGGG ARRGGYCVRRGGGGGRKGDYWYSVKGWHCVHVMV Direction: Forward Position #: 7 Overlap #: 20 Alignment: ARRGGYCHARGGGDRAGKWCAYCBTGWHCVHVMV ------BGRRRGRGGRTGRTTYGGGG-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- sgCTGGCCAGcs Combined Motif Reverse Complement Reverse Complement VRVDVGDWCYVSMWKDCRKCCCCCKKVGMCCMMT VVCTGGCCAGBB VRVVCKGGCCAGVDKDCRKCCCCCKKVGMCCMMT Direction: Forward Position #: 3 Overlap #: 12 Alignment: VRVDVGDWCYVSMWKDCRKCCCCCKKVGMCCMMT --VVCTGGCCAGBB-------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCwGGCCwGCss Combined Motif Original Motif Original Motif VRVVCKGGCCAGVDKDCRKCCCCCKKVGMCCMMT BBCWGGCCAGCBB VRVVCKBDCYRGCCDGCVBCCCCCKKVGMCCMMT Direction: Forward Position #: 7 Overlap #: 13 Alignment: VRVVCKGGCCAGVDKDCRKCCCCCKKVGMCCMMT ------BBCWGGCCAGCBB--------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Original Motif Reverse Complement VRVVCKBDCYRGCCDGCVBCCCCCKKVGMCCMMT GGYGCTGTCCATGGTGCTGAA GRHDCTGTCCVKSSTGCTGMVCCCKKVGMCCMMT Direction: Forward Position #: 1 Overlap #: 21 Alignment: VRVVCKBDCYRGCCDGCVBCCCCCKKVGMCCMMT GGYGCTGTCCATGGTGCTGAA------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 71 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wyATTTTAww wtATTTTTAww Original Motif Original Motif DHATTTTADD DHATTTTTADD DHATTTTWADD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DHATTTTADD- DHATTTTTADD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTAAwAAww Reverse Complement Original Motif DDTWAAAATHD DDTAAWAAHH DDTAAAAATHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DDTWAAAATHD DDTAAWAAHH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTAAAwAww Original Motif Original Motif DDTAAAAATHD DDTAAAWAHH DDTAAAAATHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DDTAAAAATHD DDTAAAWAHH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwWAAAAAwa Original Motif Original Motif DDTAAAAATHD WWAAAAAAWH DWWAAAAAWHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DDTAAAAATHD WWAAAAAAWH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif dwCTTTTCwy Reverse Complement Original Motif DHWTTTTTWWD DHCTTTTCHH DHCTTTTYWHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DHWTTTTTWWD DHCTTTTCHH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtTTWwAAAaw Reverse Complement Original Motif DHWKAAAAGHD HHTTTWAAADD DHTTWAAAAHD Direction: Forward Position #: 1 Overlap #: 11 Alignment: DHWKAAAAGHD HHTTTWAAADD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif twTACATAvw Reverse Complement Reverse Complement DHTTTTWAAHD DBTATGTAHH DHTWTKTAHHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DHTTTTWAAHD DBTATGTAHH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif aaCAAAAACaa Original Motif Reverse Complement DHTWTKTAHHD HTGTTTTTGHH HHKTTTTWGHH Direction: Forward Position #: 1 Overlap #: 11 Alignment: DHTWTKTAHHD HTGTTTTTGHH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif aaACAAAACaa Reverse Complement Original Motif HHCWAAAAYHH AAACAAAACAA HHAMAAAACHH Direction: Forward Position #: 1 Overlap #: 11 Alignment: HHCWAAAAYHH AAACAAAACAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Reverse Complement Reverse Complement HHGTTTTRTHH TTTTTTTTTTT TTKTTTTTTTT Direction: Forward Position #: 1 Overlap #: 11 Alignment: HHGTTTTRTHH TTTTTTTTTTT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 72 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCKCwsCGss ssCGCksCGss Original Motif Original Motif BVCGCWSCGBV VVCGCKSCGBB BVCGCTSCGBB Direction: Backward Position #: 1 Overlap #: 11 Alignment: BVCGCWSCGBV VVCGCKSCGBB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGMsGRGCGss Original Motif Reverse Complement BVCGCTSCGBB BBCGCCCSGCVV BVCGCHCCGCVV Direction: Forward Position #: 1 Overlap #: 11 Alignment: BVCGCTSCGBB- BBCGCCCSGCVV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif sssCGssGCsss Original Motif Reverse Complement BVCGCHCCGCVV SSSGCSSCGSSS BBCGCBSCGCVV Direction: Forward Position #: 1 Overlap #: 12 Alignment: BVCGCHCCGCVV SSSGCSSCGSSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGCTswGCCms Original Motif Reverse Complement BBCGCBSCGCVV BDGGCTSAGCBV BVSGCBSMGCBV Direction: Forward Position #: 1 Overlap #: 12 Alignment: BBCGCBSCGCVV BDGGCTSAGCBV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGGsYCGss Original Motif Original Motif BVSGCBSMGCBV BSCGGSCCGSV BBCGSBCCGCVV Direction: Forward Position #: 1 Overlap #: 11 Alignment: BVSGCBSMGCBV BSCGGSCCGSV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Original Motif Original Motif BBCGSBCCGCVV DGVBCABTGDWGCGKRRCSR BBVGVBCMGBGVWGCGKRRCSR Direction: Forward Position #: 3 Overlap #: 10 Alignment: BBCGSBCCGCVV---------- --DGVBCABTGDWGCGKRRCSR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCrCYyYCGss Combined Motif Original Motif Original Motif BBVGVBCMGBGVWGCGKRRCSR BBCRCCYCCGBB BBBSGCCMSCGVDGCGKRRCSR Direction: Forward Position #: 2 Overlap #: 12 Alignment: BBVGVBCMGBGVWGCGKRRCSR -BBCRCCYCCGBB--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGCCsCCrCCCss Reverse Complement Reverse Complement MSGKKRCGCDVCGSRGGCSBBB SSGGGCGGSGGCGSS VSGGGVSGCGGCGSVGGCSBBB Direction: Forward Position #: 1 Overlap #: 15 Alignment: MSGKKRCGCDVCGSRGGCSBBB SSGGGCGGSGGCGSS------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ccCCAGTGCAbr Combined Motif Reverse Complement Reverse Complement BBBSGCCVSCGCCGCSBCCCSV DBTGCACTGGVD BBBBGCMCYSGVBGCSBCCCSV Direction: Forward Position #: 2 Overlap #: 12 Alignment: BBBSGCCVSCGCCGCSBCCCSV -DBTGCACTGGVD--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGsCwsCss Combined Motif Reverse Complement Original Motif VSGGGVSGCBVCSMGYGCVBBB BBCGSCWSCBB VSGBGCGGCDSCSVGYGCVBBB Direction: Forward Position #: 4 Overlap #: 11 Alignment: VSGGGVSGCBVCSMGYGCVBBB ---BBCGSCWSCBB-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 73 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGsCTCss ssCGsCwsCss Reverse Complement Reverse Complement BBGAGSCGVV BBGSWGSCGBB BBGGAGSCGVB Direction: Forward Position #: 2 Overlap #: 10 Alignment: -BBGAGSCGVV BBGSWGSCGBB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif sssCGssGCsss Original Motif Reverse Complement BBGGAGSCGVB SSSGCSSCGSSS BBSGMGSCGSVS Direction: Forward Position #: 1 Overlap #: 11 Alignment: BBGGAGSCGVB- SSSGCSSCGSSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCksCGss Combined Motif Original Motif Reverse Complement BBSGMGSCGSVS BBCGSRGCGVV BBSGCGSCGCGSV Direction: Forward Position #: 3 Overlap #: 10 Alignment: BBSGMGSCGSVS- --BBCGSRGCGVV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGGsYCGss Reverse Complement Reverse Complement VSCGCGSCGCSBB VSCGGSCCGSB VSCGSSCCGSSBB Direction: Forward Position #: 1 Overlap #: 11 Alignment: VSCGCGSCGCSBB VSCGGSCCGSB-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Reverse Complement Original Motif BBSSCGGSSCGSV SSCGCCSCCGCCCSS BBSSCGSCSCSVCCCSS Direction: Forward Position #: 3 Overlap #: 11 Alignment: BBSSCGGSSCGSV---- --SSCGCCSCCGCCCSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGssCGss Reverse Complement Reverse Complement SSGGGVSGSGSCGSSBB VSCGSSCGSB BSSGSSCGSGSCGSSBB Direction: Forward Position #: 1 Overlap #: 10 Alignment: SSGGGVSGSGSCGSSBB VSCGSSCGSB------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGrGCGss Combined Motif Reverse Complement Reverse Complement BBSSCGSCSCGSSCSSB VBCGCMCGSV BBSSCSGCVCGSSCSSB Direction: Forward Position #: 4 Overlap #: 10 Alignment: BBSSCGSCSCGSSCSSB ---VBCGCMCGSV---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGMsGRGCGss Original Motif Reverse Complement BBSSCSGCVCGSSCSSB BBCGCCCSGCVV BBCGCCSCVCGVSCSSB Direction: Forward Position #: 1 Overlap #: 12 Alignment: BBSSCSGCVCGSSCSSB BBCGCCCSGCVV----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCKCwsCGss Combined Motif Reverse Complement Reverse Complement BSSGSVCGVGSGGCGBB VBCGSWGCGVB BSSGVCSGHGCGGBGBB Direction: Forward Position #: 4 Overlap #: 11 Alignment: BSSGSVCGVGSGGCGBB ---VBCGSWGCGVB--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCrCYyYCGss Combined Motif Reverse Complement Original Motif BBCBCCGCHCSGVCSSB BBCRCCYCCGBB BBCBBCGCYCCSGCSSB Direction: Forward Position #: 4 Overlap #: 12 Alignment: BBCBCCGCHCSGVCSSB ---BBCRCCYCCGBB-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 74 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- twTACATAvw wwTAAAwAww Reverse Complement Reverse Complement DBTATGTAHH HHTWTTTADD HHTATKTAHH Direction: Backward Position #: 1 Overlap #: 10 Alignment: DBTATGTAHH HHTWTTTADD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yayAyAyACATrya Original Motif Reverse Complement HHTATKTAHH DHKATGTKTKTGTD DHTATGTRTKTGTD Direction: Forward Position #: 1 Overlap #: 10 Alignment: HHTATKTAHH---- DHKATGTKTKTGTD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTAAwAAww Original Motif Reverse Complement DHTATGTRTKTGTD HHTTWTTADD DHTWTKTADDTGTD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DHTATGTRTKTGTD HHTTWTTADD---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtATTTTTAww Reverse Complement Reverse Complement HACADDTARAWAHD DDTAAAAATHD HDYAAAWAWAWAHD Direction: Forward Position #: 1 Overlap #: 11 Alignment: HACADDTARAWAHD DDTAAAAATHD--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wyATTTTAww Original Motif Reverse Complement HDYAAAWAWAWAHD DDTAAAATHD HDTAAAAWDHWAHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: HDYAAAWAWAWAHD DDTAAAATHD---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wrTGTATACAyw Original Motif Original Motif HDTAAAAWDHWAHD HDTGTATACAHD HDTRWAWAHAHAHD Direction: Forward Position #: 1 Overlap #: 12 Alignment: HDTAAAAWDHWAHD HDTGTATACAHD-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ryayAyAyrtGTRTrTry Combined Motif Original Motif Original Motif HDTRWAWAHAHAHD DHAYAYAYRTGTGTRTDH HDTRHAYAYATRTRTRTDH Direction: Forward Position #: 2 Overlap #: 13 Alignment: HDTRWAWAHAHAHD----- -DHAYAYAYRTGTGTRTDH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwWAAAAAwa Original Motif Original Motif HDTRHAYAYATRTRTRTDH WWAAAAAAWH DDWAAAAAHATRTRTRTDH Direction: Forward Position #: 1 Overlap #: 10 Alignment: HDTRHAYAYATRTRTRTDH WWAAAAAAWH--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtTTWwAAAaw Original Motif Original Motif DDWAAAAAHATRTRTRTDH HHTTTWAAADD HHTWWAAAADHRTRTRTDH Direction: Forward Position #: 1 Overlap #: 11 Alignment: DDWAAAAAHATRTRTRTDH HHTTTWAAADD-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Original Motif Reverse Complement HHTWWAAAADHRTRTRTDH DVTGCATGCATGBH DHTKMAWRMATGTVTRTDH Direction: Forward Position #: 1 Overlap #: 14 Alignment: HHTWWAAAADHRTRTRTDH DVTGCATGCATGBH----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 75 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- yayAyAyACATrya ryayAyAyrtGTRTrTry Original Motif Original Motif HACAYAYACATRHD DHAYAYAYRTGTGTRTDH TDHHAYAYAYAYRTRTRD Direction: Backward Position #: 4 Overlap #: 14 Alignment: -HACAYAYACATRHD--- DHAYAYAYRTGTGTRTDH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Original Motif Original Motif TDHHAYAYAYAYRTRTRD HVCATGCATGCABD HDCATRCAYRCAYRTRTRD Direction: Forward Position #: 2 Overlap #: 13 Alignment: -TDHHAYAYAYAYRTRTRD HVCATGCATGCABD----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 27 Original Motif Original Motif HDCATRCAYRCAYRTRTRD CAYACACACACACA CACAYACAYACACATRTRD Direction: Forward Position #: 1 Overlap #: 14 Alignment: HDCATRCAYRCAYRTRTRD CAYACACACACACA----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 25 Combined Motif Reverse Complement Reverse Complement DKAMATGTGTKTGTKTGTG TGTGTGKVTGTGTG DKAYRTGTGTGTGTGTGTG Direction: Forward Position #: 4 Overlap #: 14 Alignment: DKAMATGTGTKTGTKTGTG ---TGTGTGKVTGTGTG-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Ar Reverse Complement Reverse Complement CACACACACACACAKMTRD VRVDGGHACAVDDKGTHCTDWH VRCDSRHACAVRBWSWKCTDDH Direction: Forward Position #: 3 Overlap #: 19 Alignment: --CACACACACACACAKMTRD- VRVDGGHACAVDDKGTHCTDWH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTAATTAATTAww Original Motif Reverse Complement VRCDSRHACAVRBWSWKCTDDH DHTAATTAATTADH TAATTADHCABAHTVRCDSRHACAVRBWSW Direction: Backward Position #: 9 Overlap #: 6 Alignment: VRCDSRHACAVRBWSWKCTDDH-------- ----------------DHTAATTAATTADH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 76 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wwWAAAAAwa wtATTTTTAww Reverse Complement Original Motif HWTTTTTTWW DHATTTTTADD HATTTTTWWDD Direction: Backward Position #: 1 Overlap #: 10 Alignment: -HWTTTTTTWW DHATTTTTADD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTAAwAAww Original Motif Reverse Complement HATTTTTWWDD HHTTWTTADD HATTTTTADDD Direction: Forward Position #: 1 Overlap #: 10 Alignment: HATTTTTWWDD HHTTWTTADD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTAAAwAww Original Motif Reverse Complement HATTTTTADDD HHTWTTTADD HHTTTTTADDD Direction: Forward Position #: 1 Overlap #: 10 Alignment: HATTTTTADDD HHTWTTTADD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Reverse Complement Original Motif DDDTAAAAAHH AAAAAAAAAAA AAAWAAAAAWA Direction: Forward Position #: 1 Overlap #: 11 Alignment: DDDTAAAAAHH AAAAAAAAAAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif aaCAAAAACaa Reverse Complement Reverse Complement TWTTTTTWTTT HTGTTTTTGHH TTKTTTTTKTT Direction: Forward Position #: 1 Overlap #: 11 Alignment: TWTTTTTWTTT HTGTTTTTGHH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wyATTTTAww Original Motif Original Motif TTKTTTTTKTT DHATTTTADD DHDTTTTWDDT Direction: Forward Position #: 1 Overlap #: 10 Alignment: TTKTTTTTKTT DHATTTTADD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif aaACAAAACaa Original Motif Reverse Complement DHDTTTTWDDT TTGTTTTGTTT HHGTTTTRTTT Direction: Forward Position #: 1 Overlap #: 11 Alignment: DHDTTTTWDDT TTGTTTTGTTT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtTTWwAAAaw Reverse Complement Original Motif AAAMAAAACHH HHTTTWAAADD HHWTWAAAAHD Direction: Forward Position #: 1 Overlap #: 11 Alignment: AAAMAAAACHH HHTTTWAAADD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif dwCTTTTCwy Reverse Complement Original Motif DHTTTTWAWHH DHCTTTTCHH DHCTTTTCHHH Direction: Forward Position #: 1 Overlap #: 10 Alignment: DHTTTTWAWHH DHCTTTTCHH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 26 Combined Motif Original Motif Original Motif DHCTTTTCHHH TKKTTTGTTTTTTT DTBTTTTVWTTTTTT Direction: Forward Position #: 2 Overlap #: 10 Alignment: DHCTTTTCHHH---- -TKKTTTGTTTTTTT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 77 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssGCTswGCCms sssCGssGCsss Original Motif Original Motif VBGCTSAGCCHB SSSCGSSGCSSS VBGCKSVGCCVB Direction: Forward Position #: 1 Overlap #: 12 Alignment: VBGCTSAGCCHB SSSCGSSGCSSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGMsGRGCGss Reverse Complement Reverse Complement BVGGCVSYGCBV BBCGCCCSGCVV BVSGCMCYGCVV Direction: Forward Position #: 1 Overlap #: 12 Alignment: BVGGCVSYGCBV BBCGCCCSGCVV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfx Combined Motif Original Motif Original Motif BVSGCMCYGCVV BBVGCCBVGGCCTV BVSGCVCCGCGGCCTV Direction: Forward Position #: 3 Overlap #: 10 Alignment: BVSGCMCYGCVV---- --BBVGCCBVGGCCTV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccCCAGTGCAbr Original Motif Reverse Complement BVSGCVCCGCGGCCTV DBTGCACTGGVD BBBGCACYGSVVCCTV Direction: Forward Position #: 1 Overlap #: 12 Alignment: BVSGCVCCGCGGCCTV DBTGCACTGGVD---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif tyTCTkTkTCyy Original Motif Original Motif BBBGCACYGSVVCCTV BBTCTKTKTCHB TKTCHBCHYCKGBBBGCACYGS Direction: Backward Position #: 7 Overlap #: 6 Alignment: BBBGCACYGSVVCCTV------ ----------BBTCTKTKTCHB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCwGGCCwGCss Reverse Complement Original Motif SCMGTGCVBBCRGMHGVHGARA BBCWGGCCAGCBB VCCDKGCCHGCVBMHGVHGARA Direction: Forward Position #: 1 Overlap #: 13 Alignment: SCMGTGCVBBCRGMHGVHGARA BBCWGGCCAGCBB--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Original Motif Reverse Complement VCCDKGCCHGCVBMHGVHGARA GGYGCTGTCCATGGTGCTGAA GGYVCYGKSCMHGSTGCTGAHGARA Direction: Forward Position #: 4 Overlap #: 18 Alignment: ---VCCDKGCCHGCVBMHGVHGARA GGYGCTGTCCATGGTGCTGAA---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Reverse Complement Original Motif TKTCHTCAGCASCHRGSRCMGVKCC HWDAGHACRHHVTGTHCCHVMV TKTCHHHAGHACVHVGBGYHSCDVCV Direction: Forward Position #: 5 Overlap #: 21 Alignment: TKTCHTCAGCASCHRGSRCMGVKCC- ----HWDAGHACRHHVTGTHCCHVMV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Original Motif Original Motif TKTCHHHAGHACVHVGBGYHSCDVCV DGVBCABTGDWGCGKRRCSR TKTCDDHDVHVYVDDGBGTVVCVVCV Direction: Forward Position #: 5 Overlap #: 20 Alignment: TKTCHHHAGHACVHVGBGYHSCDVCV ----DGVBCABTGDWGCGKRRCSR-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Original Motif Reverse Complement TKTCDDHDVHVYVDDGBGTVVCVVCV TGRCCTKTGHCCKAB TKWCCKBTGHMCBHVGBGTVVCVVCV Direction: Forward Position #: 1 Overlap #: 15 Alignment: TKTCDDHDVHVYVDDGBGTVVCVVCV TGRCCTKTGHCCKAB----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 78 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- sssCGssGCsss ssGMsGRGCGss Reverse Complement Reverse Complement SSSGCSSCGSSS BBCGCCCSGCVV BBCGCSCCGCVV Direction: Forward Position #: 1 Overlap #: 12 Alignment: SSSGCSSCGSSS BBCGCCCSGCVV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGCTswGCCms Reverse Complement Original Motif VVGCGGSGCGBB VBGCTSAGCCHB VVGCKSVGCSVB Direction: Forward Position #: 1 Overlap #: 12 Alignment: VVGCGGSGCGBB VBGCTSAGCCHB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Reverse Complement Original Motif BVSGCBSRGCVV SSCGCCSCCGCCCSS BVSGCGCMGCCVCCCSS Direction: Forward Position #: 3 Overlap #: 10 Alignment: BVSGCBSRGCVV----- --SSCGCCSCCGCCCSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Zfx Original Motif Reverse Complement BVSGCGCMGCCVCCCSS VAGGCCBBGGCVBB VAGGCCSVGSCVCCCSS Direction: Forward Position #: 1 Overlap #: 14 Alignment: BVSGCGCMGCCVCCCSS VAGGCCBBGGCVBB--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCrCYyYCGss Reverse Complement Reverse Complement SSGGGVGSCVSGGCCTV BBCGGKGGMGBB BSSGGVGGCGBSGCCTV Direction: Forward Position #: 1 Overlap #: 12 Alignment: SSGGGVGSCVSGGCCTV BBCGGKGGMGBB----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccCCAGTGCAbr Reverse Complement Reverse Complement VAGGCSBCGCCVCCSSB DBTGCACTGGVD BVKGCMCYGSBBCCSSB Direction: Forward Position #: 1 Overlap #: 12 Alignment: VAGGCSBCGCCVCCSSB DBTGCACTGGVD----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Reverse Complement Reverse Complement BSSGGBBSCMGYGCRBB MGGTCAGGGTGACCTRDBHV MGGTCVSGGTGVCCKBGCVBB Direction: Forward Position #: 5 Overlap #: 16 Alignment: ----BSSGGBBSCMGYGCRBB MGGTCAGGGTGACCTRDBHV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Original Motif Reverse Complement MGGTCVSGGTGVCCKBGCVBB MSGKKRCGCWDCABTGBBCD MGGTCVGGKDSVCHKBRBHDBBCD Direction: Forward Position #: 5 Overlap #: 17 Alignment: MGGTCVSGGTGVCCKBGCVBB--- ----MSGKKRCGCWDCABTGBBCD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Reverse Complement Original Motif HGVBHHBMBRHGVSDYCCBGACCY HWDAGHACRHHVTGTHCCHVMV HGVBHHDHRGHRCRHYVYGDACCHVMV Direction: Forward Position #: 6 Overlap #: 19 Alignment: HGVBHHBMBRHGVSDYCCBGACCY--- -----HWDAGHACRHHVTGTHCCHVMV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif sgCTGGCCAGcs Reverse Complement Reverse Complement VRVHGGTDCKVKHKGMHCKHDHDBBCD VVCTGGCCAGBB VDCTGGCCMGVBHKGMHCKHDHDBBCD Direction: Forward Position #: 1 Overlap #: 12 Alignment: VRVHGGTDCKVKHKGMHCKHDHDBBCD VVCTGGCCAGBB--------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 79 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CACACACACACA CACACACACACA Original Motif Original Motif CACACACACACA CACACACACACA CACACACACACA Direction: Backward Position #: 1 Overlap #: 12 Alignment: CACACACACACA CACACACACACA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 27 Reverse Complement Reverse Complement TGTGTGTGTGTG TGTGTGTGTGTKTG TGTGTGTGTGTGTG Direction: Forward Position #: 1 Overlap #: 12 Alignment: TGTGTGTGTGTG-- TGTGTGTGTGTKTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 25 Reverse Complement Original Motif CACACACACACACA CACACAVRCACACA CACACACACACACA Direction: Forward Position #: 1 Overlap #: 14 Alignment: CACACACACACACA CACACAVRCACACA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yayAyAyACATrya Original Motif Original Motif CACACACACACACA HACAYAYACATRHD CACACACACAYACA Direction: Forward Position #: 1 Overlap #: 14 Alignment: CACACACACACACA HACAYAYACATRHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ryayAyAyrtGTRTrTry Original Motif Original Motif CACACACACAYACA DHAYAYAYRTGTGTRTDH DYAYACAYAYRTRYRTDH Direction: Forward Position #: 2 Overlap #: 14 Alignment: -CACACACACAYACA--- DHAYAYAYRTGTGTRTDH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif tyTCTkTkTCyy Original Motif Reverse Complement DYAYACAYAYRTRYRTDH VHGARAYAGAVV VHGAVAYASAHVTRYRTDH Direction: Forward Position #: 2 Overlap #: 11 Alignment: -DYAYACAYAYRTRYRTDH VHGARAYAGAVV------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Original Motif Original Motif VHGAVAYASAHVTRYRTDH HVCATGCATGCABD HVCATRCAKRCAYRYRTDH Direction: Forward Position #: 1 Overlap #: 14 Alignment: VHGAVAYASAHVTRYRTDH HVCATGCATGCABD----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RREB1 Original Motif Original Motif HVCATRCAKRCAYRYRTDH CCCCMAAMCAMCCMCMMMCV CCMCMAHVCAHMCMCVHMYVH Direction: Forward Position #: 3 Overlap #: 18 Alignment: --HVCATRCAKRCAYRYRTDH CCCCMAAMCAMCCMCMMMCV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 26 Combined Motif Original Motif Reverse Complement CCMCMAHVCAHMCMCVHMYVH AAAAAAACAAARRA CCMCAAAAMAHCMAHDDAYVH Direction: Forward Position #: 5 Overlap #: 14 Alignment: CCMCMAHVCAHMCMCVHMYVH ----AAAAAAACAAARRA--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yrTGTGCACAyr Reverse Complement Reverse Complement HBKTDDHTYGHTYTTTTGRGG BBTGTGCACAVV ACAVVBBTGTKYHBKTDDHTYGHTYT Direction: Backward Position #: 6 Overlap #: 7 Alignment: HBKTDDHTYGHTYTTTTGRGG----- --------------BBTGTGCACAVV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 80 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCwGGCCwGCss ESR1 Reverse Complement Reverse Complement BBGCTGGCCWGBB MGGTCAGGGTGACCTRDBHV MGGTCAVGCTGRCCWGBBHV Direction: Forward Position #: 6 Overlap #: 13 Alignment: -----BBGCTGGCCWGBB-- MGGTCAGGGTGACCTRDBHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- REST Combined Motif Original Motif Reverse Complement MGGTCAVGCTGRCCWGBBHV GGYGCTGTCCATGGTGCTGAA MGGTSVBGCTGDCCWDGGTVCTGAA Direction: Forward Position #: 5 Overlap #: 16 Alignment: MGGTCAVGCTGRCCWGBBHV----- ----GGYGCTGTCCATGGTGCTGAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Original Motif Reverse Complement MGGTSVBGCTGDCCWDGGTVCTGAA DVTGCATGCATGBH DMKGYVTGSMTGDCCWDGGTVCTGAA Direction: Forward Position #: 2 Overlap #: 13 Alignment: -MGGTSVBGCTGDCCWDGGTVCTGAA DVTGCATGCATGBH------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Pax5 Original Motif Original Motif DMKGYVTGSMTGDCCWDGGTVCTGAA DGVBCABTGDWGCGKRRCSR DRDGCABBSVTGBVYDDSSDVCTGAA Direction: Forward Position #: 1 Overlap #: 20 Alignment: DMKGYVTGSMTGDCCWDGGTVCTGAA DGVBCABTGDWGCGKRRCSR------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Reverse Complement Original Motif TTCAGVDSSHDKVBCABSBVTGCDMD HWDAGHACRHHVTGTHCCHVMV HTHAGHACRHHVBGYWCCBVHVCDMD Direction: Forward Position #: 1 Overlap #: 22 Alignment: TTCAGVDSSHDKVBCABSBVTGCDMD HWDAGHACRHHVTGTHCCHVMV---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Original Motif Original Motif HTHAGHACRHHVBGYWCCBVHVCDMD SSCGCCSCCGCCCSS HTHAGVVCRCCSCSBMCCBVHVCDMD Direction: Forward Position #: 6 Overlap #: 15 Alignment: HTHAGHACRHHVBGYWCCBVHVCDMD -----SSCGCCSCCGCCCSS------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RREB1 Reverse Complement Reverse Complement DRDGVDVBGGRVSGSGGMGBVCTDAH BGRRRGRGGRTGRTTYGGGG BGDGVGVGGGTGGBYBGVGDVCTDAH Direction: Forward Position #: 1 Overlap #: 20 Alignment: DRDGVDVBGGRVSGSGGMGBVCTDAH BGRRRGRGGRTGRTTYGGGG------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif sgCTGGCCAGcs Reverse Complement Original Motif HTHAGVHCVCVMVCCACCCVCVCHCV BBCTGGCCAGVV HDCWGGCCASVVVCCACCCVCVCHCV Direction: Forward Position #: 1 Overlap #: 12 Alignment: HTHAGVHCVCVMVCCACCCVCVCHCV BBCTGGCCAGVV-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGCTswGCCms Reverse Complement Reverse Complement BGDGVGVGGGTGGBBBSTGGCCWGDH BDGGCTSAGCBV BVGGCDSRGSDVGBBBSTGGCCWGDH Direction: Forward Position #: 1 Overlap #: 12 Alignment: BGDGVGVGGGTGGBBBSTGGCCWGDH BDGGCTSAGCBV-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccCCAGTGCAbr Original Motif Reverse Complement BVGGCDSRGSDVGBBBSTGGCCWGDH DBTGCACTGGVD BVKGCACWGGDVGBBBSTGGCCWGDH Direction: Forward Position #: 1 Overlap #: 12 Alignment: BVGGCDSRGSDVGBBBSTGGCCWGDH DBTGCACTGGVD-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 81 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wwTAAwAAww wwTAAAwAww Original Motif Original Motif DDTAAWAAHH DDTAAAWAHH DDTAAAAAHH Direction: Backward Position #: 1 Overlap #: 10 Alignment: DDTAAWAAHH DDTAAAWAHH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtATTTTTAww Original Motif Reverse Complement DDTAAAAAHH DDTAAAAATHD DDTAAAAATHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DDTAAAAAHH- DDTAAAAATHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwWAAAAAwa Original Motif Original Motif DDTAAAAATHD WWAAAAAAWH DWWAAAAATHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DDTAAAAATHD WWAAAAAAWH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wyATTTTAww Original Motif Reverse Complement DWWAAAAATHD DDTAAAATHD DDTAAAAWHHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DWWAAAAATHD DDTAAAATHD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtTTWwAAAaw Reverse Complement Reverse Complement DHHWTTTTADD DDTTTWAAAHH DDTTTTWWAHD Direction: Forward Position #: 1 Overlap #: 11 Alignment: DHHWTTTTADD DDTTTWAAAHH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif aaCAAAAACaa Reverse Complement Original Motif DHTWWAAAADD HHCAAAAACAH HHYAAAAAMHH Direction: Forward Position #: 1 Overlap #: 11 Alignment: DHTWWAAAADD HHCAAAAACAH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif dwCTTTTCwy Original Motif Reverse Complement HHYAAAAAMHH DHGAAAAGHD DHBAAAARHDH Direction: Forward Position #: 1 Overlap #: 10 Alignment: HHYAAAAAMHH DHGAAAAGHD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif twTACATAvw Original Motif Original Motif DHBAAAARHDH HHTACATAVD DHTAMAWAHDH Direction: Forward Position #: 1 Overlap #: 10 Alignment: DHBAAAARHDH HHTACATAVD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTAATTAATTAww Original Motif Reverse Complement DHTAMAWAHDH DHTAATTAATTADH DHTAAWTAATTADH Direction: Forward Position #: 1 Overlap #: 11 Alignment: DHTAMAWAHDH--- DHTAATTAATTADH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Reverse Complement Reverse Complement HDTAATTAWTTAHD TTTTTTTTTTT TTTTTTTWTTTAHD Direction: Forward Position #: 1 Overlap #: 11 Alignment: HDTAATTAWTTAHD TTTTTTTTTTT--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 82 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rmACAGCAGsr ssCGsCwsCss Original Motif Reverse Complement VVACAGCAGVD BBGSWGSCGBB VVRCAGCMGVV Direction: Forward Position #: 1 Overlap #: 11 Alignment: VVACAGCAGVD BBGSWGSCGBB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 83 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wwTAAAwAww wwTAAwAAww Original Motif Original Motif DDTAAAWAHH DDTAAWAAHH DDTAAAAAHH Direction: Backward Position #: 1 Overlap #: 10 Alignment: DDTAAAWAHH DDTAAWAAHH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtATTTTTAww Original Motif Reverse Complement DDTAAAAAHH DDTAAAAATHD DDTAAAAATHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DDTAAAAAHH- DDTAAAAATHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwWAAAAAwa Original Motif Original Motif DDTAAAAATHD WWAAAAAAWH DWWAAAAATHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DDTAAAAATHD WWAAAAAAWH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif twTACATAvw Original Motif Original Motif DWWAAAAATHD HHTACATAVD DHTAMAWAHHD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DWWAAAAATHD HHTACATAVD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wyATTTTAww Original Motif Reverse Complement DHTAMAWAHHD DDTAAAATHD DHTAAAAWHDD Direction: Forward Position #: 1 Overlap #: 10 Alignment: DHTAMAWAHHD DDTAAAATHD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif aaCAAAAACaa Original Motif Original Motif DHTAAAAWHDD HHCAAAAACAH HHYAAAAACHH Direction: Forward Position #: 1 Overlap #: 11 Alignment: DHTAAAAWHDD HHCAAAAACAH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtTTWwAAAaw Original Motif Original Motif HHYAAAAACHH HHTTTWAAADD HHTWWAAAMHD Direction: Forward Position #: 1 Overlap #: 11 Alignment: HHYAAAAACHH HHTTTWAAADD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTAATTAATTAww Original Motif Reverse Complement HHTWWAAAMHD DHTAATTAATTADH HHTAAWWAATTADH Direction: Forward Position #: 1 Overlap #: 11 Alignment: HHTWWAAAMHD--- DHTAATTAATTADH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif dwCTTTTCwy Original Motif Reverse Complement HHTAAWWAATTADH DHGAAAAGHD DHKAAAARADTADH Direction: Forward Position #: 1 Overlap #: 10 Alignment: HHTAAWWAATTADH DHGAAAAGHD---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Original Motif Original Motif DHKAAAARADTADH AAAAAAAAAAA DARAAAAAAWWADH Direction: Forward Position #: 1 Overlap #: 11 Alignment: DHKAAAARADTADH AAAAAAAAAAA--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 84 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wsAGCTACwy Ar Reverse Complement Original Motif VHGTAGCTVD HWDAGHACRHHVTGTHCCHVMV HDHRKARCWBHVTGTHCCHVMV Direction: Forward Position #: 2 Overlap #: 10 Alignment: -VHGTAGCTVD----------- HWDAGHACRHHVTGTHCCHVMV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Reverse Complement Reverse Complement VRVDGGHACAVDBWGMTRMHDH GGYGCTGTCCATGGTGCTGAA GGDVCKGTMCABGGTGCTGMDDH Direction: Forward Position #: 2 Overlap #: 20 Alignment: -VRVDGGHACAVDBWGMTRMHDH GGYGCTGTCCATGGTGCTGAA-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Original Motif Original Motif GGDVCKGTMCABGGTGCTGMDDH DGVBCABTGDWGCGKRRCSR GGDVVKGTMMVBGDWGCKKADCVR Direction: Forward Position #: 5 Overlap #: 19 Alignment: GGDVCKGTMCABGGTGCTGMDDH- ----DGVBCABTGDWGCGKRRCSR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGCksCGss Original Motif Reverse Complement GGDVVKGTMMVBGDWGCKKADCVR BBCGSRGCGVV GVCGSDGCSVVBGDWGCKKADCVR Direction: Forward Position #: 1 Overlap #: 11 Alignment: GGDVVKGTMMVBGDWGCKKADCVR BBCGSRGCGVV------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCKCwsCGss Original Motif Reverse Complement GVCGSDGCSVVBGDWGCKKADCVR VBCGSWGCGVB BVCGSDGCGVVBGDWGCKKADCVR Direction: Forward Position #: 1 Overlap #: 11 Alignment: GVCGSDGCSVVBGDWGCKKADCVR VBCGSWGCGVB------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif rmACAGCAGsr Original Motif Reverse Complement BVCGSDGCGVVBGDWGCKKADCVR DVCTGCTGTVB DVCYGCTGYGBVBGDWGCKKADCVR Direction: Forward Position #: 2 Overlap #: 10 Alignment: -BVCGSDGCGVVBGDWGCKKADCVR DVCTGCTGTVB-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- aaCAAAAACaa Combined Motif Original Motif Reverse Complement DVCYGCTGYGBVBGDWGCKKADCVR HTGTTTTTGHH DVCYGBTGTKTTTGDWGCKKADCVR Direction: Forward Position #: 6 Overlap #: 11 Alignment: DVCYGCTGYGBVBGDWGCKKADCVR -----HTGTTTTTGHH--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGsCwsCss Reverse Complement Original Motif MVGDTYRGCWHCAAARACABCMGVD BBCGSCWSCBB VVCGBCWGCDBCAAARACABCMGVD Direction: Forward Position #: 1 Overlap #: 11 Alignment: MVGDTYRGCWHCAAARACABCMGVD BBCGSCWSCBB-------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ryayAyAyrtGTRTrTry Reverse Complement Reverse Complement DVCYGBTGTKTTTGBDGCWGBCGVV HDAMACACAKKTKTKTHD HDAHACWSHTGTKTKTVDDGCWGBCGVV Direction: Forward Position #: 4 Overlap #: 15 Alignment: ---DVCYGBTGTKTTTGBDGCWGBCGVV HDAMACACAKKTKTKTHD---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGsCTCss Reverse Complement Original Motif VVCGBCWGCDDVARAYACAHSWGTDTDH VVCGSCTCBB VVCGSCTSCVDVARAYACAHSWGTDTDH Direction: Forward Position #: 1 Overlap #: 10 Alignment: VVCGBCWGCDDVARAYACAHSWGTDTDH VVCGSCTCBB------------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 85 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wtATTTTTAww aaCAAAAACaa Original Motif Reverse Complement DHATTTTTADD HTGTTTTTGHH HHRTTTTTRDH Direction: Forward Position #: 1 Overlap #: 11 Alignment: DHATTTTTADD HTGTTTTTGHH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtTTWwAAAaw Original Motif Reverse Complement HHRTTTTTRDH DDTTTWAAAHH DHDTTTWWAHH Direction: Forward Position #: 1 Overlap #: 11 Alignment: HHRTTTTTRDH DDTTTWAAAHH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Reverse Complement Original Motif HHTWWAAADHD AAAAAAAAAAA AAWAAAAAAAA Direction: Forward Position #: 1 Overlap #: 11 Alignment: HHTWWAAADHD AAAAAAAAAAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif aaACAAAACaa Reverse Complement Reverse Complement TTTTTTTTWTT TTGTTTTGTTT TTKTTTTKTTT Direction: Forward Position #: 1 Overlap #: 11 Alignment: TTTTTTTTWTT TTGTTTTGTTT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif tyTCTkTkTCyy Original Motif Original Motif TTKTTTTKTTT BBTCTKTKTCHB BHTYTTTKTCHB Direction: Forward Position #: 1 Overlap #: 11 Alignment: TTKTTTTKTTT- BBTCTKTKTCHB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTAATTAATTAww Reverse Complement Reverse Complement VHGARAAAMAHV DHTAATTAATTADH HHKAAWWAAWWADH Direction: Forward Position #: 1 Overlap #: 12 Alignment: VHGARAAAMAHV-- DHTAATTAATTADH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif NR2F1 Reverse Complement Original Motif HDTWWTTWWTTRHH TGAMCTTTGMMCYT TGAMCTTTRVHHHTTWWTTRHH Direction: Forward Position #: 9 Overlap #: 6 Alignment: --------HDTWWTTWWTTRHH TGAMCTTTGMMCYT-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 26 Reverse Complement Reverse Complement HHKAAWWAAHDHBMAAAGRTCA AAAAAAACAAARRA AAWAAAWMAAADDAAAAGRTCA Direction: Forward Position #: 1 Overlap #: 14 Alignment: HHKAAWWAAHDHBMAAAGRTCA AAAAAAACAAARRA-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yayAyAyACATrya Original Motif Original Motif AAWAAAWMAAADDAAAAGRTCA HACAYAYACATRHD HAHAHAHACAWRHDAAAAGRTCA Direction: Forward Position #: 2 Overlap #: 13 Alignment: -AAWAAAWMAAADDAAAAGRTCA HACAYAYACATRHD--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ryayAyAyrtGTRTrTry Combined Motif Reverse Complement Original Motif TGAMCTTTTDHKWTGTHTHTDTD DHAYAYAYRTGTGTRTDH TGAMCTWTWYABATGTDTDTDTD Direction: Forward Position #: 5 Overlap #: 18 Alignment: TGAMCTTTTDHKWTGTHTHTDTD ----DHAYAYAYRTGTGTRTDH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 86 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- aaCAAAAACaa aaACAAAACaa Reverse Complement Reverse Complement HTGTTTTTGHH TTGTTTTGTTT TTGTTTTKKTT Direction: Backward Position #: 1 Overlap #: 11 Alignment: HTGTTTTTGHH TTGTTTTGTTT ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtATTTTTAww Original Motif Original Motif TTGTTTTKKTT DHATTTTTADD HHRTTTTTRDH Direction: Forward Position #: 1 Overlap #: 11 Alignment: TTGTTTTKKTT DHATTTTTADD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Reverse Complement Original Motif HDKAAAAAKHH AAAAAAAAAAA AAAAAAAADAA Direction: Forward Position #: 1 Overlap #: 11 Alignment: HDKAAAAAKHH AAAAAAAAAAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yayAyAyACATrya Reverse Complement Reverse Complement TTDTTTTTTTT DHKATGTKTKTGTD THKWTKTTTKTGTD Direction: Forward Position #: 1 Overlap #: 11 Alignment: TTDTTTTTTTT--- DHKATGTKTKTGTD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACACACACACA Original Motif Reverse Complement THKWTKTTTKTGTD TGTGTGTGTGTG TBTKTGTKTGTGTD Direction: Forward Position #: 1 Overlap #: 12 Alignment: THKWTKTTTKTGTD TGTGTGTGTGTG-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif tyTCTkTkTCyy Original Motif Original Motif TBTKTGTKTGTGTD BBTCTKTKTCHB TBTCTKTKTSTBTD Direction: Forward Position #: 1 Overlap #: 12 Alignment: TBTKTGTKTGTGTD BBTCTKTKTCHB-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACACACACACA Original Motif Reverse Complement TBTCTKTKTSTBTD TGTGTGTGTGTG TGTSTGTGTGTGTD Direction: Forward Position #: 1 Overlap #: 12 Alignment: TBTCTKTKTSTBTD TGTGTGTGTGTG-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 27 Reverse Complement Original Motif HACACACACASACA CAYACACACACACA CACACACACACACA Direction: Forward Position #: 1 Overlap #: 14 Alignment: HACACACACASACA CAYACACACACACA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RREB1 Combined Motif Reverse Complement Reverse Complement TGTGTGTGTGTGTG BGRRRGRGGRTGRTTYGGGG TGTGKGTGKGKGTGRTTYGGGG Direction: Forward Position #: 3 Overlap #: 12 Alignment: TGTGTGTGTGTGTG-------- --BGRRRGRGGRTGRTTYGGGG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 26 Original Motif Original Motif TGTGKGTGKGKGTGRTTYGGGG TKKTTTGTTTTTTT TTKTKTGTKTKTKTGRTTYGGGG Direction: Forward Position #: 2 Overlap #: 13 Alignment: -TGTGKGTGKGKGTGRTTYGGGG TKKTTTGTTTTTTT--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 87 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGGsYCGss ssCGCksCGss Original Motif Reverse Complement BSCGGSCCGSV BBCGSRGCGVV BSCGGVSCGSV Direction: Forward Position #: 1 Overlap #: 11 Alignment: BSCGGSCCGSV BBCGSRGCGVV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- sssCGssGCsss Combined Motif Reverse Complement Original Motif VSCGSVCCGSB SSSCGSSGCSSS VSCGCGSCGCSSS Direction: Forward Position #: 2 Overlap #: 10 Alignment: VSCGSVCCGSB-- -SSSCGSSGCSSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCKCwsCGss Original Motif Original Motif VSCGCGSCGCSSS BVCGCWSCGBV BVCGCDSCGCSSS Direction: Forward Position #: 1 Overlap #: 11 Alignment: VSCGCGSCGCSSS BVCGCWSCGBV-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGMsGRGCGss Original Motif Reverse Complement BVCGCDSCGCSSS BBCGCCCSGCVV BVCGCVCCGCVVS Direction: Forward Position #: 1 Overlap #: 12 Alignment: BVCGCDSCGCSSS BBCGCCCSGCVV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif sgCTGGCCAGcs Original Motif Original Motif BVCGCVCCGCVVS BBCTGGCCAGVV BBCKSGCCRSVVS Direction: Forward Position #: 1 Overlap #: 12 Alignment: BVCGCVCCGCVVS BBCTGGCCAGVV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGsCwsCss Reverse Complement Reverse Complement SVVSKGGCSRGBB BBGSWGSCGBB BVGSWGGCGVGBB Direction: Forward Position #: 1 Overlap #: 11 Alignment: SVVSKGGCSRGBB BBGSWGSCGBB-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCwGGCCwGCss Original Motif Reverse Complement BVGSWGGCGVGBB BBGCTGGCCWGBB BBGCWGGCSDGBB Direction: Forward Position #: 1 Overlap #: 13 Alignment: BVGSWGGCGVGBB BBGCTGGCCWGBB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCrCYyYCGss Reverse Complement Original Motif BBCDSGCCWGCBB BBCRCCYCCGBB BBCDCSCCMGCBB Direction: Forward Position #: 1 Overlap #: 12 Alignment: BBCDSGCCWGCBB BBCRCCYCCGBB- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Reverse Complement Reverse Complement BBGCRGGSGHGBB SSGGGCGGSGGCGSS BBGCGGGBGVGGGCGSS Direction: Forward Position #: 3 Overlap #: 11 Alignment: BBGCRGGSGHGBB---- --SSGGGCGGSGGCGSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Reverse Complement Reverse Complement SSCGCCCVCBCCCGCBB VRVDGGHACAVDDKGTHCTDWH SSCGVCBVSDMCMSBBBGTHCTDWH Direction: Forward Position #: 4 Overlap #: 14 Alignment: SSCGCCCVCBCCCGCBB-------- ---VRVDGGHACAVDDKGTHCTDWH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 88 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCrCYyYCGss ssCGCCsCCrCCCss Reverse Complement Reverse Complement BBCGGKGGMGBB SSGGGCGGSGGCGSS SSGGGCGGGGGCGBB Direction: Forward Position #: 4 Overlap #: 12 Alignment: ---BBCGGKGGMGBB SSGGGCGGSGGCGSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGMsGRGCGss Reverse Complement Reverse Complement BBCGCCCCCGCCCSS BBCGCCCSGCVV BBCGCCCCSSCCCSS Direction: Forward Position #: 1 Overlap #: 12 Alignment: BBCGCCCCCGCCCSS BBCGCCCSGCVV--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif sssCGssGCsss Original Motif Reverse Complement BBCGCCCCSSCCCSS SSSGCSSCGSSS SBCGCSSCGSSSCSS Direction: Forward Position #: 1 Overlap #: 12 Alignment: BBCGCCCCSSCCCSS SSSGCSSCGSSS--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Zfx Original Motif Reverse Complement SBCGCSSCGSSSCSS VAGGCCBBGGCVBB VASGCCBCGSCSCSS Direction: Forward Position #: 1 Overlap #: 14 Alignment: SBCGCSSCGSSSCSS VAGGCCBBGGCVBB- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Reverse Complement Original Motif SSGSGSCGBGGCSTV DGVBCABTGDWGCGKRRCSR SSDGVSCDBKGMVGVGKRRCSR Direction: Forward Position #: 3 Overlap #: 13 Alignment: SSGSGSCGBGGCSTV------- --DGVBCABTGDWGCGKRRCSR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- sgCTGGCCAGcs Combined Motif Original Motif Original Motif SSDGVSCDBKGMVGVGKRRCSR BBCTGGCCAGVV SSDGVBCTGGSCAGVGKRRCSR Direction: Forward Position #: 5 Overlap #: 12 Alignment: SSDGVSCDBKGMVGVGKRRCSR ----BBCTGGCCAGVV------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RREB1 Original Motif Reverse Complement SSDGVBCTGGSCAGVGKRRCSR BGRRRGRGGRTGRTTYGGGG BGRVVGRGGSTGGYYHGVGKRRCSR Direction: Forward Position #: 4 Overlap #: 17 Alignment: ---SSDGVBCTGGSCAGVGKRRCSR BGRRRGRGGRTGRTTYGGGG----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCwGGCCwGCss Combined Motif Reverse Complement Reverse Complement MSGKKYCVCHKKCCASCCMCVVMCB BBGCTGGCCWGBB MSGKKHCSCWGGCCAGBVMCVVMCB Direction: Forward Position #: 6 Overlap #: 13 Alignment: MSGKKYCVCHKKCCASCCMCVVMCB -----BBGCTGGCCWGBB------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ccCCAGTGCAbr Combined Motif Original Motif Reverse Complement MSGKKHCSCWGGCCAGBVMCVVMCB DBTGCACTGGVD MSGBTGCACTGGHCAGBVMCVVMCB Direction: Forward Position #: 3 Overlap #: 12 Alignment: MSGKKHCSCWGGCCAGBVMCVVMCB --DBTGCACTGGVD----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfp423 Combined Motif Original Motif Reverse Complement MSGBTGCACTGGHCAGBVMCVVMCB GYRYCCMTKGGYRSC MSGBDBCCCTGGGYASCVMCVVMCB Direction: Forward Position #: 3 Overlap #: 15 Alignment: MSGBTGCACTGGHCAGBVMCVVMCB --GYRYCCMTKGGYRSC-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 89 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ccCCmCACCcc ssCGCCsCCrCCCss Original Motif Original Motif HBCCMCACCHH SSCGCCSCCGCCCSS SVCCCCCACCCBSSC Direction: Backward Position #: 2 Overlap #: 11 Alignment: ---HBCCMCACCHH- SSCGCCSCCGCCCSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGsCwsCss Reverse Complement Reverse Complement GSSBGGGTGGGGGVS BBGSWGSCGBB GBGSDGGYGGGGGVS Direction: Forward Position #: 1 Overlap #: 11 Alignment: GSSBGGGTGGGGGVS BBGSWGSCGBB---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RREB1 Combined Motif Original Motif Reverse Complement GBGSDGGYGGGGGVS BGRRRGRGGRTGRTTYGGGG GBBSRGGBGGGGTGVTTYGGGG Direction: Forward Position #: 3 Overlap #: 13 Alignment: GBGSDGGYGGGGGVS------- --BGRRRGRGGRTGRTTYGGGG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rrAGGGGGArr Combined Motif Original Motif Original Motif GBBSRGGBGGGGTGVTTYGGGG VVAGGGGGAVV GBBSDGRGGGGGWGVTTYGGGG Direction: Forward Position #: 5 Overlap #: 11 Alignment: GBBSRGGBGGGGTGVTTYGGGG ----VVAGGGGGAVV------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCrCYyYCGss Combined Motif Original Motif Reverse Complement GBBSDGRGGGGGWGVTTYGGGG BBCGGKGGMGBB GBBSVGMGGGGGMGVBTYGGGG Direction: Forward Position #: 5 Overlap #: 12 Alignment: GBBSDGRGGGGGWGVTTYGGGG ----BBCGGKGGMGBB------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- REST Combined Motif Reverse Complement Original Motif CCCCMAVVCYCCCCCRCVSBBC TTCAGCACCATGGACAGCKCC CCCCMAVVCYCYYCMGCACCVYGGACAGCKCC Direction: Forward Position #: 12 Overlap #: 11 Alignment: CCCCMAVVCYCCCCCRCVSBBC---------- -----------TTCAGCACCATGGACAGCKCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGCTswGCCms Reverse Complement Reverse Complement GGYGCTGTCCKBGGTGCYGMKGMGVBTYGGGG BDGGCTSAGCBV BVBGCTSWSCBBGGTGCYGMKGMGVBTYGGGG Direction: Forward Position #: 1 Overlap #: 12 Alignment: GGYGCTGTCCKBGGTGCYGMKGMGVBTYGGGG BDGGCTSAGCBV-------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Egr1 Reverse Complement Reverse Complement CCCCMAVVCYCYYCMGCACCVBGSWSAGCBVB YCGCCCACGCH YCSCCMACGCHCYYCMGCACCVBGSWSAGCBVB Direction: Forward Position #: 2 Overlap #: 10 Alignment: -CCCCMAVVCYCYYCMGCACCVBGSWSAGCBVB YCGCCCACGCH---------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGMsGRGCGss Reverse Complement Reverse Complement BVBGCTSWSCBBGGTGCYGMKGHGCGTRGGSGK BBCGCCCSGCVV BVCGCYSHGCBBGGTGCYGMKGHGCGTRGGSGK Direction: Forward Position #: 1 Overlap #: 12 Alignment: BVBGCTSWSCBBGGTGCYGMKGHGCGTRGGSGK BBCGCCCSGCVV--------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif INSM1 Original Motif Reverse Complement BVCGCYSHGCBBGGTGCYGMKGHGCGTRGGSGK MGCCCCCTGMCA VGCSCCCWGCCVGGTGCYGMKGHGCGTRGGSGK Direction: Forward Position #: 1 Overlap #: 12 Alignment: BVCGCYSHGCBBGGTGCYGMKGHGCGTRGGSGK MGCCCCCTGMCA--------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 90 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGsCwsCss ssCrCYyYCGss Original Motif Original Motif BBCGSCWSCBB BBCRCCYCCGBB BBBCGCCHSCGB Direction: Backward Position #: 2 Overlap #: 11 Alignment: BBCGSCWSCBB- BBCRCCYCCGBB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccCCmCACCcc Reverse Complement Reverse Complement BCGSHGGCGBBB DDGGTGRGGBD BBGGTGGSGBVB Direction: Forward Position #: 1 Overlap #: 11 Alignment: BCGSHGGCGBBB DDGGTGRGGBD- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif sssCGssGCsss Original Motif Reverse Complement BBGGTGGSGBVB SSSGCSSCGSSS BBGGYGGCGSVB Direction: Forward Position #: 1 Overlap #: 12 Alignment: BBGGTGGSGBVB SSSGCSSCGSSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Original Motif Reverse Complement BBGGYGGCGSVB SSGGGCGGSGGCGSS BBGGBGGCGGSGGCGSS Direction: Forward Position #: 3 Overlap #: 10 Alignment: BBGGYGGCGSVB----- --SSGGGCGGSGGCGSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 91 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Ar Original Motif Original Motif SSCGCCSCCGCCCSS HWDAGHACRHHVTGTHCCHVMV MVVMCRCCSYSKCCCBVHWDAG Direction: Backward Position #: 3 Overlap #: 15 Alignment: -----SSCGCCSCCGCCCSS-- HWDAGHACRHHVTGTHCCHVMV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RREB1 Original Motif Original Motif MVVMCRCCSYSKCCCBVHWDAG CCCCMAAMCAMCCMCMMMCV CCMCMAMVCMCCCHCCCHSHWDAG Direction: Forward Position #: 3 Overlap #: 18 Alignment: --MVVMCRCCSYSKCCCBVHWDAG CCCCMAAMCAMCCMCMMMCV---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Pax5 Original Motif Reverse Complement CCMCMAMVCMCCCHCCCHSHWDAG MSGKKRCGCWDCABTGBBCD MCVBDACVCHBCMVYVCHCDWDAG Direction: Forward Position #: 1 Overlap #: 20 Alignment: CCMCMAMVCMCCCHCCCHSHWDAG MSGKKRCGCWDCABTGBBCD---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR2 Original Motif Original Motif MCVBDACVCHBCMVYVCHCDWDAG VHRGGTCABDBTGMCCTB MVRGGWCACDBYVHCCYBCDWDAG Direction: Forward Position #: 1 Overlap #: 18 Alignment: MCVBDACVCHBCMVYVCHCDWDAG VHRGGTCABDBTGMCCTB------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Original Motif Original Motif MVRGGWCACDBYVHCCYBCDWDAG VDBHMAGGTCACCCTGACCY MVRGGDCVCHDBGDCMBBCTGAMSY Direction: Forward Position #: 6 Overlap #: 19 Alignment: MVRGGWCACDBYVHCCYBCDWDAG- -----VDBHMAGGTCACCCTGACCY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfx Combined Motif Reverse Complement Original Motif MSRTCAGBBYGDCBDDGBGDCCMVR BBVGCCBVGGCCTV MSVBVDSBBHGGCCTVGBGDCCMVR Direction: Forward Position #: 3 Overlap #: 14 Alignment: MSRTCAGBBYGDCBDDGBGDCCMVR --BBVGCCBVGGCCTV--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PLAG1 Combined Motif Reverse Complement Original Motif MVRGGDCVCVAGGCCDBBSHVVVSY GGGGCCCAAGGGGG MVGGGGCCCHAGGSSGBBSHVVVSY Direction: Forward Position #: 3 Overlap #: 14 Alignment: MVRGGDCVCVAGGCCDBBSHVVVSY --GGGGCCCAAGGGGG--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Original Motif Original Motif MVGGGGCCCHAGGSSGBBSHVVVSY BTRGGDCARAGGKCA MVDRGGBCMAAGGBSRBBSHVVVSY Direction: Forward Position #: 2 Overlap #: 15 Alignment: MVGGGGCCCHAGGSSGBBSHVVVSY -BTRGGDCARAGGKCA--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Tcfcp2l1 Combined Motif Reverse Complement Original Motif MSVBVDSBBKSBCCTTYGBCCMHVR CCAGYYHVADCCRG MSCCVGBYBDVBCCDGYGBCCMHVR Direction: Forward Position #: 3 Overlap #: 14 Alignment: MSVBVDSBBKSBCCTTYGBCCMHVR --CCAGYYHVADCCRG--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCwGGCCwGCss Original Motif Reverse Complement MSCCVGBYBDVBCCDGYGBCCMHVR BBGCTGGCCWGBB VBSCDGGCCWGBCCDGYGBCCMHVR Direction: Forward Position #: 1 Overlap #: 13 Alignment: MSCCVGBYBDVBCCDGYGBCCMHVR BBGCTGGCCWGBB------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 92 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- tyTCTkTkTCyy yayAyAyACATrya Reverse Complement Original Motif VHGARAYAGAVV HACAYAYACATRHD HAHASAHACAKAHV Direction: Forward Position #: 3 Overlap #: 12 Alignment: --VHGARAYAGAVV HACAYAYACATRHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACACACACACA Reverse Complement Reverse Complement BDTYTGTHTSTDTD TGTGTGTGTGTG TGTBTGTGTGTGTD Direction: Forward Position #: 1 Overlap #: 12 Alignment: BDTYTGTHTSTDTD TGTGTGTGTGTG-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 93 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- rrAGGGGGArr ssCrCYyYCGss Reverse Complement Original Motif VVTCCCCCTVV BBCRCCYCCGBB BVVYSCCCCYGV Direction: Backward Position #: 2 Overlap #: 11 Alignment: VVTCCCCCTVV- BBCRCCYCCGBB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccCCmCACCcc Original Motif Original Motif BVVYSCCCCYGV HBCCMCACCHH VVCCCCMCCYVV Direction: Forward Position #: 1 Overlap #: 11 Alignment: BVVYSCCCCYGV HBCCMCACCHH- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif INSM1 Original Motif Reverse Complement VVCCCCMCCYVV MGCCCCCTGMCA VBCCCCCYSHCV Direction: Forward Position #: 1 Overlap #: 12 Alignment: VVCCCCMCCYVV MGCCCCCTGMCA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RREB1 Combined Motif Original Motif Original Motif VBCCCCCYSHCV CCCCMAAMCAMCCMCMMMCV VBCCCCMMMMCAMCCMCMMMCV Direction: Forward Position #: 3 Overlap #: 10 Alignment: VBCCCCCYSHCV---------- --CCCCMAAMCAMCCMCMMMCV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Original Motif Original Motif VBCCCCMMMMCAMCCMCMMMCV SSCGCCSCCGCCCSS VBCCCCCVCCCMCVCCCHVMCV Direction: Forward Position #: 5 Overlap #: 15 Alignment: VBCCCCMMMMCAMCCMCMMMCV ----SSCGCCSCCGCCCSS--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Egr1 Combined Motif Reverse Complement Original Motif BGRVDGGGVGYGGGBGGGGGBV HGCGTGGGCGK BGRVDGSGKGBGVGKGGGGGBV Direction: Forward Position #: 5 Overlap #: 11 Alignment: BGRVDGGGVGYGGGBGGGGGBV ----HGCGTGGGCGK------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGMsGRGCGss Original Motif Original Motif BGRVDGSGKGBGVGKGGGGGBV VVGCSGGGCGBB BSGVBGGGYGBGVGKGGGGGBV Direction: Forward Position #: 1 Overlap #: 12 Alignment: BGRVDGSGKGBGVGKGGGGGBV VVGCSGGGCGBB---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 94 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCksCGss ssCKCwsCGss Original Motif Original Motif VVCGCKSCGBB BVCGCWSCGBV BVCGCTSCGBB Direction: Forward Position #: 1 Overlap #: 11 Alignment: VVCGCKSCGBB BVCGCWSCGBV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- sssCGssGCsss Combined Motif Original Motif Original Motif BVCGCTSCGBB SSSCGSSGCSSS BVCGCKSCGCSSS Direction: Forward Position #: 2 Overlap #: 10 Alignment: BVCGCTSCGBB-- -SSSCGSSGCSSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGGsYCGss Original Motif Reverse Complement BVCGCKSCGCSSS VSCGGSCCGSB VSCGSGCCGSSSS Direction: Forward Position #: 1 Overlap #: 11 Alignment: BVCGCKSCGCSSS VSCGGSCCGSB-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssGMsGRGCGss Combined Motif Reverse Complement Reverse Complement SSSSCGGCSCGSV BBCGCCCSGCVV SSBBCGSCCCGCVV Direction: Forward Position #: 3 Overlap #: 11 Alignment: SSSSCGGCSCGSV- --BBCGCCCSGCVV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGCTswGCCms Reverse Complement Original Motif VVGCGGGSCGBBSS VBGCTSAGCCHB VVGCKSDGCSVBSS Direction: Forward Position #: 1 Overlap #: 12 Alignment: VVGCGGGSCGBBSS VBGCTSAGCCHB-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCrCYyYCGss Original Motif Reverse Complement VVGCKSDGCSVBSS BBCGGKGGMGBB VBSSKGGGCGBBSS Direction: Forward Position #: 1 Overlap #: 12 Alignment: VVGCKSDGCSVBSS BBCGGKGGMGBB-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGCCsCCrCCCss Combined Motif Reverse Complement Original Motif SSBBCGCCCYSSBV SSCGCCSCCGCCCSS SSBBCGCCSCCGCCCSS Direction: Forward Position #: 3 Overlap #: 12 Alignment: SSBBCGCCCYSSBV--- --SSCGCCSCCGCCCSS ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCGsCwsCss Combined Motif Original Motif Reverse Complement SSBBCGCCSCCGCCCSS BBGSWGSCGBB SSBBCGCHGCCGSBCSS Direction: Forward Position #: 4 Overlap #: 11 Alignment: SSBBCGCCSCCGCCCSS ---BBGSWGSCGBB--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Reverse Complement Reverse Complement SSGBSCGGCDGCGBBSS MSGKKRCGCWDCABTGBBCD SSGVSSGKVVGCDBSVBTGBBCD Direction: Forward Position #: 4 Overlap #: 14 Alignment: SSGBSCGGCDGCGBBSS------ ---MSGKKRCGCWDCABTGBBCD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfx Combined Motif Reverse Complement Original Motif HGVBCABBSVHGCVVYCSSVCSS BBVGCCBVGGCCTV HGVBVDSYBVGGCCTBCSSVCSS Direction: Forward Position #: 3 Overlap #: 14 Alignment: HGVBCABBSVHGCVVYCSSVCSS --BBVGCCBVGGCCTV------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 95 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CACACACACACA CACACACACACA Original Motif Original Motif CACACACACACA CACACACACACA CACACACACACA Direction: Backward Position #: 1 Overlap #: 12 Alignment: CACACACACACA CACACACACACA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 27 Reverse Complement Reverse Complement TGTGTGTGTGTG TGTGTGTGTGTKTG TGTGTGTGTGTGTG Direction: Forward Position #: 1 Overlap #: 12 Alignment: TGTGTGTGTGTG-- TGTGTGTGTGTKTG ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 25 Reverse Complement Original Motif CACACACACACACA CACACAVRCACACA CACACACACACACA Direction: Forward Position #: 1 Overlap #: 14 Alignment: CACACACACACACA CACACAVRCACACA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yayAyAyACATrya Original Motif Original Motif CACACACACACACA HACAYAYACATRHD CACACACACAYACA Direction: Forward Position #: 1 Overlap #: 14 Alignment: CACACACACACACA HACAYAYACATRHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ryayAyAyrtGTRTrTry Original Motif Original Motif CACACACACAYACA DHAYAYAYRTGTGTRTDH DYAYACAYAYRTRYRTDH Direction: Forward Position #: 2 Overlap #: 14 Alignment: -CACACACACAYACA--- DHAYAYAYRTGTGTRTDH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif tyTCTkTkTCyy Original Motif Reverse Complement DYAYACAYAYRTRYRTDH VHGARAYAGAVV VHGAVAYASAHVTRYRTDH Direction: Forward Position #: 2 Overlap #: 11 Alignment: -DYAYACAYAYRTRYRTDH VHGARAYAGAVV------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Original Motif Original Motif VHGAVAYASAHVTRYRTDH HVCATGCATGCABD HVCATRCAKRCAYRYRTDH Direction: Forward Position #: 1 Overlap #: 14 Alignment: VHGAVAYASAHVTRYRTDH HVCATGCATGCABD----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif RREB1 Original Motif Original Motif HVCATRCAKRCAYRYRTDH CCCCMAAMCAMCCMCMMMCV CCMCMAHVCAHMCMCVHMYVH Direction: Forward Position #: 3 Overlap #: 18 Alignment: --HVCATRCAKRCAYRYRTDH CCCCMAAMCAMCCMCMMMCV- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Motif 26 Combined Motif Original Motif Reverse Complement CCMCMAHVCAHMCMCVHMYVH AAAAAAACAAARRA CCMCAAAAMAHCMAHDDAYVH Direction: Forward Position #: 5 Overlap #: 14 Alignment: CCMCMAHVCAHMCMCVHMYVH ----AAAAAAACAAARRA--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yrTGTGCACAyr Reverse Complement Reverse Complement HBKTDDHTYGHTYTTTTGRGG BBTGTGCACAVV ACAVVBBTGTKYHBKTDDHTYGHTYT Direction: Backward Position #: 6 Overlap #: 7 Alignment: HBKTDDHTYGHTYTTTTGRGG----- --------------BBTGTGCACAVV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 96 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- yrTGTGCACAyr wrTGTATACAyw Original Motif Original Motif BVTGTGCACABV HDTGTATACAHD HVTGTRYACABD Direction: Backward Position #: 1 Overlap #: 12 Alignment: BVTGTGCACABV HDTGTATACAHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Ar Original Motif Reverse Complement HVTGTRYACABD VRVDGGHACAVDDKGTHCTDWH BRTGKGYACAVDDKGTHCTDWH Direction: Forward Position #: 1 Overlap #: 12 Alignment: HVTGTRYACABD---------- VRVDGGHACAVDDKGTHCTDWH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- yayAyAyACATrya Combined Motif Original Motif Original Motif BRTGKGYACAVDDKGTHCTDWH HACAYAYACATRHD BRHDYRYACACATDGWHCTDWH Direction: Forward Position #: 3 Overlap #: 14 Alignment: BRTGKGYACAVDDKGTHCTDWH --HACAYAYACATRHD------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Original Motif Original Motif BRHDYRYACACATDGWHCTDWH HVCATGCATGCABD BDCATRCAYRCABDGWHCTDWH Direction: Forward Position #: 1 Overlap #: 14 Alignment: BRHDYRYACACATDGWHCTDWH HVCATGCATGCABD-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PPARGRXRA Reverse Complement Original Motif HWDAGHWCHVTGKMTGMATGDV BTRGGDCARAGGKCA VHDRGDHMVAKGKMWGMATGDV Direction: Forward Position #: 1 Overlap #: 15 Alignment: HWDAGHWCHVTGKMTGMATGDV BTRGGDCARAGGKCA------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccCCAGTGCAbr Reverse Complement Reverse Complement BDCATRCWRRCYTBYDDCMDHV DBTGCACTGGVD BDYRYACTGGCBTBYDDCMDHV Direction: Forward Position #: 1 Overlap #: 12 Alignment: BDCATRCWRRCYTBYDDCMDHV DBTGCACTGGVD---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACACACACACA Original Motif Original Motif BDYRYACTGGCBTBYDDCMDHV CACACACACACA BACACACWSRCHTBYDDCMDHV Direction: Forward Position #: 1 Overlap #: 12 Alignment: BDYRYACTGGCBTBYDDCMDHV CACACACACACA---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACACACACACA Original Motif Original Motif BACACACWSRCHTBYDDCMDHV CACACACACACA CACACACACACATBYDDCMDHV Direction: Forward Position #: 1 Overlap #: 12 Alignment: BACACACWSRCHTBYDDCMDHV CACACACACACA---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ESR1 Combined Motif Reverse Complement Reverse Complement VHDRGDHMVATGTGTGTGTGTG MGGTCAGGGTGACCTRDBHV VHDRGGHCARDGTGWSYKKGBBV Direction: Forward Position #: 4 Overlap #: 19 Alignment: VHDRGDHMVATGTGTGTGTGTG- ---MGGTCAGGGTGACCTRDBHV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCwGGCCwGCss Original Motif Original Motif VHDRGGHCARDGTGWSYKKGBBV BBCWGGCCAGCBB VHCDGGCCAGBBTGWSYKKGBBV Direction: Forward Position #: 1 Overlap #: 13 Alignment: VHDRGGHCARDGTGWSYKKGBBV BBCWGGCCAGCBB---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 97 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ryayAyAyrtGTRTrTry Ar Reverse Complement Reverse Complement HDAMACACAKKTKTKTHD VRVDGGHACAVDDKGTHCTDWH HVKRHACACDKKKKTBTHDVRV Direction: Backward Position #: 2 Overlap #: 18 Alignment: ---HDAMACACAKKTKTKTHD- VRVDGGHACAVDDKGTHCTDWH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Pax5 Original Motif Reverse Complement HVKRHACACDKKKKTBTHDVRV MSGKKRCGCWDCABTGBBCD MSDDKRMRCWBVDKKKYBHDDVRV Direction: Forward Position #: 3 Overlap #: 18 Alignment: --HVKRHACACDKKKKTBTHDVRV MSGKKRCGCWDCABTGBBCD---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zfp423 Combined Motif Original Motif Original Motif MSDDKRMRCWBVDKKKYBHDDVRV GSMMCCYARGGKKKC MSGBVMCCCADGGKKKHBHDDVRV Direction: Forward Position #: 3 Overlap #: 15 Alignment: MSDDKRMRCWBVDKKKYBHDDVRV --GSMMCCYARGGKKKC------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NR2F1 Combined Motif Original Motif Reverse Complement MSGBVMCCCADGGKKKHBHDDVRV AKGYYCAAAGRTCA MSGVDRCBCAARGRTCABHDDVRV Direction: Forward Position #: 4 Overlap #: 14 Alignment: MSGBVMCCCADGGKKKHBHDDVRV ---AKGYYCAAAGRTCA------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif PPARGRXRA Reverse Complement Reverse Complement VMVDDDBTGAMCKTTGBGMHBCSR TGRCCTKTGHCCKAB DVVHCTKTGVCCKHBGBGMHBCSR Direction: Forward Position #: 1 Overlap #: 15 Alignment: VMVDDDBTGAMCKTTGBGMHBCSR TGRCCTKTGHCCKAB--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- yayAyAyACATrya Combined Motif Reverse Complement Original Motif MSGVDRCBCVHRGGBCARAGDBVD HACAYAYACATRHD MSGVBRCACAHASRTVHVAGDBVD Direction: Forward Position #: 5 Overlap #: 14 Alignment: MSGVDRCBCVHRGGBCARAGDBVD ----HACAYAYACATRHD------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- AAAAAAAAAAA Combined Motif Original Motif Reverse Complement MSGVBRCACAHASRTVHVAGDBVD DVTGCATGCATGBH MSGVBVYRCATRCATGHVAGDBVD Direction: Forward Position #: 5 Overlap #: 14 Alignment: MSGVBRCACAHASRTVHVAGDBVD ----DVTGCATGCATGBH------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 98 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wwTAATTAATTAww yayAyAyACATrya Original Motif Original Motif HDTAATTAATTAHD HACAYAYACATRHD HDYAHWTAMWTAHD Direction: Forward Position #: 1 Overlap #: 14 Alignment: HDTAATTAATTAHD HACAYAYACATRHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Original Motif Original Motif HDYAHWTAMWTAHD HVCATGCATGCABD HDYATRYAHDYAHD Direction: Forward Position #: 1 Overlap #: 14 Alignment: HDYAHWTAMWTAHD HVCATGCATGCABD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Motif 26 Reverse Complement Original Motif DHTKHHTKMATKDH TKKTTTGTTTTTTT TDDTTTVTKTWTKTH Direction: Forward Position #: 2 Overlap #: 13 Alignment: -DHTKHHTKMATKDH TKKTTTGTTTTTTT- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wrTGTATACAyw Reverse Complement Reverse Complement HARAWARAVAAADDA DHTGTATACADH HADRTAWACADADDA Direction: Forward Position #: 1 Overlap #: 12 Alignment: HARAWARAVAAADDA DHTGTATACADH--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wtTTWwAAAaw Combined Motif Original Motif Original Motif HADRTAWACADADDA HHTTTWAAADD HADDTWWAAAADDDA Direction: Forward Position #: 3 Overlap #: 11 Alignment: HADRTAWACADADDA --HHTTTWAAADD-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wtATTTTTAww Combined Motif Original Motif Reverse Complement HADDTWWAAAADDDA DDTAAAAATHD HADDTAAAAAWHDDA Direction: Forward Position #: 3 Overlap #: 11 Alignment: HADDTWWAAAADDDA --DDTAAAAATHD-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Reverse Complement Reverse Complement TDDHWTTTTTADDTH TTTTTTTTTTT TTTTTTTTTTWDDTH Direction: Forward Position #: 1 Overlap #: 11 Alignment: TDDHWTTTTTADDTH TTTTTTTTTTT---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTAAAwAww Original Motif Reverse Complement TTTTTTTTTTWDDTH HHTWTTTADD TDTWTTTWTTWDDTH Direction: Forward Position #: 1 Overlap #: 10 Alignment: TTTTTTTTTTWDDTH HHTWTTTADD----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTAAwAAww Original Motif Reverse Complement TDTWTTTWTTWDDTH HHTTWTTADD HHTTTTTATDWDDTH Direction: Forward Position #: 1 Overlap #: 10 Alignment: TDTWTTTWTTWDDTH HHTTWTTADD----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif twTACATAvw Original Motif Reverse Complement HHTTTTTATDWDDTH DBTATGTAHH HHTWTKTAHHWDDTH Direction: Forward Position #: 1 Overlap #: 10 Alignment: HHTTTTTATDWDDTH DBTATGTAHH----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 99 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- sgCTGGCCAGcs ssCwGGCCwGCss Original Motif Original Motif BBCTGGCCAGVV BBCWGGCCAGCBB BBCTGGCCAGCVB Direction: Forward Position #: 1 Overlap #: 12 Alignment: BBCTGGCCAGVV- BBCWGGCCAGCBB ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ESR1 Reverse Complement Original Motif BVGCTGGCCAGBB VDBHMAGGTCACCCTGACCY VBBBCWGGYCAGBBTGACCY Direction: Forward Position #: 2 Overlap #: 13 Alignment: -BVGCTGGCCAGBB------ VDBHMAGGTCACCCTGACCY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Original Motif Reverse Complement VBBBCWGGYCAGBBTGACCY GGYGCTGTCCATGGTGCTGAA GVHBCTGKCCABGGTGMYSHA Direction: Forward Position #: 1 Overlap #: 20 Alignment: VBBBCWGGYCAGBBTGACCY- GGYGCTGTCCATGGTGCTGAA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCrCYyYCGss Original Motif Reverse Complement GVHBCTGKCCABGGTGMYSHA BBCGGKGGMGBB VVCGSKGGCSVBGGTGMYSHA Direction: Forward Position #: 1 Overlap #: 12 Alignment: GVHBCTGKCCABGGTGMYSHA BBCGGKGGMGBB--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Ar Reverse Complement Original Motif THSMRCACCBBSGCCRSCGVV HWDAGHACRHHVTGTHCCHVMV HHVAGMACVBHSDSYDCCBVHV Direction: Forward Position #: 1 Overlap #: 21 Alignment: THSMRCACCBBSGCCRSCGVV- HWDAGHACRHHVTGTHCCHVMV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- sssCGssGCsss Combined Motif Original Motif Original Motif HHVAGMACVBHSDSYDCCBVHV SSSCGSSGCSSS HHVAGVVCGSBGCSBVCCBVHV Direction: Forward Position #: 5 Overlap #: 12 Alignment: HHVAGMACVBHSDSYDCCBVHV ----SSSCGSSGCSSS------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Original Motif Original Motif HHVAGVVCGSBGCSBVCCBVHV DGVBCABTGDWGCGKRRCSR DDVVVVVYGVHGCGBRVCVVHV Direction: Forward Position #: 1 Overlap #: 20 Alignment: HHVAGVVCGSBGCSBVCCBVHV DGVBCABTGDWGCGKRRCSR-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssGMsGRGCGss Combined Motif Original Motif Original Motif DDVVVVVYGVHGCGBRVCVVHV VVGCSGGGCGBB DDVVVVGCGVRGCGBVVCVVHV Direction: Forward Position #: 5 Overlap #: 12 Alignment: DDVVVVVYGVHGCGBRVCVVHV ----VVGCSGGGCGBB------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Reverse Complement Original Motif VDVVGVVBCGCMVCGCVVBBHD HVCATGCATGCABD BDCAKGCAYGCAHVGCVVBBHD Direction: Forward Position #: 1 Overlap #: 14 Alignment: VDVVGVVBCGCMVCGCVVBBHD HVCATGCATGCABD-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCGGsYCGss Original Motif Reverse Complement BDCAKGCAYGCAHVGCVVBBHD VSCGGSCCGSB VVCGKSCCGGCAHVGCVVBBHD Direction: Forward Position #: 1 Overlap #: 11 Alignment: BDCAKGCAYGCAHVGCVVBBHD VSCGGSCCGSB----------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 100 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wrTGTATACAyw yrTGTGCACAyr Original Motif Original Motif HDTGTATACAHD BVTGTGCACABV HVTGTRYACABD Direction: Forward Position #: 1 Overlap #: 12 Alignment: HDTGTATACAHD BVTGTGCACABV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Original Motif Reverse Complement HVTGTRYACABD DVTGCATGCATGBH BVTGYATRCATGBH Direction: Forward Position #: 1 Overlap #: 12 Alignment: HVTGTRYACABD-- DVTGCATGCATGBH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yayAyAyACATrya Original Motif Original Motif BVTGYATRCATGBH HACAYAYACATRHD BVYRYAYACATRBV Direction: Forward Position #: 1 Overlap #: 14 Alignment: BVTGYATRCATGBH HACAYAYACATRHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Reverse Complement Original Motif BVMATGTMTMKMBV HWDAGHACRHHVTGTHCCHVMV BVMATRKMWCDMHVTGTHCCHVMV Direction: Forward Position #: 3 Overlap #: 12 Alignment: BVMATGTMTMKMBV---------- --HWDAGHACRHHVTGTHCCHVMV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif tyTCTkTkTCyy Reverse Complement Reverse Complement VRVDGGHACAVHYHGWYYMATRBV VHGARAYAGAVV VDGARRYASAVVYHGWYYMATRBV Direction: Forward Position #: 1 Overlap #: 12 Alignment: VRVDGGHACAVHYHGWYYMATRBV VHGARAYAGAVV------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ccCCAGTGCAbr Original Motif Original Motif VDGARRYASAVVYHGWYYMATRBV HVCCAGTGCABD VVSMAGTRCAVVYHGWYYMATRBV Direction: Forward Position #: 1 Overlap #: 12 Alignment: VDGARRYASAVVYHGWYYMATRBV HVCCAGTGCABD------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACACACACACA Original Motif Original Motif VVSMAGTRCAVVYHGWYYMATRBV CACACACACACA VACAMRYACAVAYHGWYYMATRBV Direction: Forward Position #: 1 Overlap #: 12 Alignment: VVSMAGTRCAVVYHGWYYMATRBV CACACACACACA------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wwTAATTAATTAww Reverse Complement Original Motif BVMATRKMWCDMTVTGTKKRTGTV HDTAATTAATTAHD HDTAWKTAAYTAHDTGTKKRTGTV Direction: Forward Position #: 1 Overlap #: 14 Alignment: BVMATRKMWCDMTVTGTKKRTGTV HDTAATTAATTAHD---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ryayAyAyrtGTRTrTry Reverse Complement Original Motif VACAMRYACAHHTAMTTARWTADH DHAYAYAYRTGTGTRTDH DHACACAYAYRTRTRHDTARWTADH Direction: Forward Position #: 2 Overlap #: 17 Alignment: -VACAMRYACAHHTAMTTARWTADH DHAYAYAYRTGTGTRTDH------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- REST Combined Motif Original Motif Original Motif DHACACAYAYRTRTRHDTARWTADH TTCAGCACCATGGACAGCKCC RTRHDTARWTADHAHRSACASVBVYDHACACAYAYRTR Direction: Backward Position #: 14 Overlap #: 12 Alignment: ---------DHACACAYAYRTRTRHDTARWTADH -------------TTCAGCACCATGGACAGCKCC ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 101 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- AAAAAAAAAAA yayAyAyACATrya Original Motif Original Motif HVCATGCATGCABD HACAYAYACATRHD HDCATRCAYRYAHD Direction: Backward Position #: 1 Overlap #: 14 Alignment: HVCATGCATGCABD HACAYAYACATRHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ryayAyAyrtGTRTrTry Original Motif Original Motif HDCATRCAYRYAHD DHAYAYAYRTGTGTRTDH DHACAYAYAYRTRTRTDH Direction: Forward Position #: 2 Overlap #: 14 Alignment: -HDCATRCAYRYAHD--- DHAYAYAYRTGTGTRTDH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pax5 Combined Motif Reverse Complement Original Motif HDAKAKAMMTKTMTGTHD DGVBCABTGDWGCGKRRCSR HDADRDVCABKKMTGBRKRRCSR Direction: Forward Position #: 4 Overlap #: 15 Alignment: HDAKAKAMMTKTMTGTHD----- ---DGVBCABTGDWGCGKRRCSR ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 102 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- AAAAAAAAAAA Motif 26 Original Motif Reverse Complement AAAAAAAAAAA AAAAAAACAAARRA AAAAAAAMAAAAAA Direction: Forward Position #: 3 Overlap #: 11 Alignment: --AAAAAAAAAAA- AAAAAAACAAARRA ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- aaACAAAACaa Combined Motif Original Motif Original Motif AAAAAAAMAAAAAA AAACAAAACAA AAAAAMAAAAMAAA Direction: Forward Position #: 3 Overlap #: 11 Alignment: AAAAAAAMAAAAAA --AAACAAAACAA- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif aaCAAAAACaa Reverse Complement Reverse Complement TTTRTTTTRTTTTT HTGTTTTTGHH TTKTTTTTGTTTTT Direction: Forward Position #: 1 Overlap #: 11 Alignment: TTTRTTTTRTTTTT HTGTTTTTGHH--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wtATTTTTAww Original Motif Original Motif TTKTTTTTGTTTTT DHATTTTTADD THRTTTTTRTHTTT Direction: Forward Position #: 1 Overlap #: 11 Alignment: TTKTTTTTGTTTTT DHATTTTTADD--- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif tyTCTkTkTCyy Original Motif Original Motif THRTTTTTRTHTTT BBTCTKTKTCHB HHTYTTTTWCHTTT Direction: Forward Position #: 1 Overlap #: 12 Alignment: THRTTTTTRTHTTT BBTCTKTKTCHB-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACACACACACA Original Motif Reverse Complement HHTYTTTTWCHTTT TGTGTGTGTGTG TBTBTKTKTSTBTT Direction: Forward Position #: 1 Overlap #: 12 Alignment: HHTYTTTTWCHTTT TGTGTGTGTGTG-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif CACACACACACA Original Motif Reverse Complement TBTBTKTKTSTBTT TGTGTGTGTGTG TGTGTGTGTGTGTT Direction: Forward Position #: 1 Overlap #: 12 Alignment: TBTBTKTKTSTBTT TGTGTGTGTGTG-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yayAyAyACATrya Reverse Complement Original Motif AACACACACACACA HACAYAYACATRHD HACACAYACAYAHA Direction: Forward Position #: 1 Overlap #: 14 Alignment: AACACACACACACA HACAYAYACATRHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wtTTWwAAAaw Combined Motif Reverse Complement Reverse Complement TDTMTGTKTGTGTH DDTTTWAAAHH TDTMTGTKTTTTTWAAHH Direction: Forward Position #: 8 Overlap #: 7 Alignment: TDTMTGTKTGTGTH---- -------DDTTTWAAAHH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ryayAyAyrtGTRTrTry Combined Motif Reverse Complement Original Motif HHTTWAAAAAYACAYAHA DHAYAYAYRTGTGTRTDH HHTTHAHAHAYAYRTRTRTDH Direction: Forward Position #: 4 Overlap #: 15 Alignment: HHTTWAAAAAYACAYAHA--- ---DHAYAYAYRTGTGTRTDH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 103 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ccCCAGTGCAbr ESR1 Original Motif Original Motif HVCCAGTGCABD VDBHMAGGTCACCCTGACCY VBBCCAGKKCABHCTGACCY Direction: Forward Position #: 2 Overlap #: 12 Alignment: -HVCCAGTGCABD------- VDBHMAGGTCACCCTGACCY ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ar Combined Motif Original Motif Original Motif VBBCCAGKKCABHCTGACCY HWDAGHACRHHVTGTHCCHVMV VBHHHAGDRCABHVTGWCCYHVMV Direction: Forward Position #: 3 Overlap #: 18 Alignment: VBBCCAGKKCABHCTGACCY---- --HWDAGHACRHHVTGTHCCHVMV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssGCTswGCCms Reverse Complement Original Motif VRVDKGGWCAVDBTGKDCTDDDBV VBGCTSAGCCHB VVGCTSRGCCAVDBTGKDCTDDDBV Direction: Forward Position #: 2 Overlap #: 11 Alignment: -VRVDKGGWCAVDBTGKDCTDDDBV VBGCTSAGCCHB------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssGMsGRGCGss Combined Motif Original Motif Reverse Complement VVGCTSRGCCAVDBTGKDCTDDDBV BBCGCCCSGCVV VVGCBBCGCCMVGCBGKDCTDDDBV Direction: Forward Position #: 5 Overlap #: 12 Alignment: VVGCTSRGCCAVDBTGKDCTDDDBV ----BBCGCCCSGCVV--------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif ssCwGGCCwGCss Original Motif Reverse Complement VVGCBBCGCCMVGCBGKDCTDDDBV BBGCTGGCCWGBB BVGCTGSSCMGBDCBGKDCTDDDBV Direction: Forward Position #: 1 Overlap #: 13 Alignment: VVGCBBCGCCMVGCBGKDCTDDDBV BBGCTGGCCWGBB------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- sssCGssGCsss Combined Motif Original Motif Original Motif BVGCTGSSCMGBDCBGKDCTDDDBV SSSCGSSGCSSS BVGCTSSSCVSSGCBSBDCTDDDBV Direction: Forward Position #: 6 Overlap #: 12 Alignment: BVGCTGSSCMGBDCBGKDCTDDDBV -----SSSCGSSGCSSS-------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PPARGRXRA Combined Motif Reverse Complement Reverse Complement VBHHHAGDBSBGCSSVGSSSAGCVB TGRCCTKTGHCCKAB VBHHHWGDCCKKYSBCSBVSAGCVB Direction: Forward Position #: 6 Overlap #: 15 Alignment: VBHHHAGDBSBGCSSVGSSSAGCVB -----TGRCCTKTGHCCKAB----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif REST Original Motif Reverse Complement VBHHHWGDCCKKYSBCSBVSAGCVB GGYGCTGTCCATGGTGCTGAA GVHBCTGTCCHKKGTSCTGVAGCVB Direction: Forward Position #: 1 Overlap #: 21 Alignment: VBHHHWGDCCKKYSBCSBVSAGCVB GGYGCTGTCCATGGTGCTGAA---- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ssCrCYyYCGss Combined Motif Original Motif Original Motif GVHBCTGTCCHKKGTSCTGVAGCVB BBCRCCYCCGBB GVHBCYGCCCYCGSBSCTGVAGCVB Direction: Forward Position #: 4 Overlap #: 12 Alignment: GVHBCTGTCCHKKGTSCTGVAGCVB ---BBCRCCYCCGBB---------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif Pax5 Reverse Complement Reverse Complement BVGCTBCAGSVSCGKGGGCKGBDVC MSGKKRCGCWDCABTGBBCD HVGBKDCRSDDCMBDGBBCKGBDVC Direction: Forward Position #: 1 Overlap #: 20 Alignment: BVGCTBCAGSVSCGKGGGCKGBDVC MSGKKRCGCWDCABTGBBCD----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- *************************************************************** Combined Motifs for Top Best Match Motif ID 104 and Its Best Matches ************************************************************** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1st motif name 2nd motif name 1st format 2nd format 1st motif 2nd motif Combined motif ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wtTTWwAAAaw wtATTTTTAww Reverse Complement Original Motif DDTTTWAAAHH DHATTTTTADD DHWTTTWWAHH Direction: Backward Position #: 1 Overlap #: 11 Alignment: DDTTTWAAAHH DHATTTTTADD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif wrTGTATACAyw Reverse Complement Reverse Complement HHTWWAAAWHD DHTGTATACADH DHTDWAWAHADH Direction: Forward Position #: 1 Overlap #: 11 Alignment: HHTWWAAAWHD- DHTGTATACADH ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- wwTAATTAATTAww Combined Motif Reverse Complement Original Motif HDTDTWTWHAHD HDTAATTAATTAHD HDWDTAWWTAATTAHD Direction: Forward Position #: 3 Overlap #: 10 Alignment: HDTDTWTWHAHD---- --HDTAATTAATTAHD ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif AAAAAAAAAAA Reverse Complement Reverse Complement DHTAATTAWWTADWDH TTTTTTTTTTT TTTWTTTWTTTADWDH Direction: Forward Position #: 1 Overlap #: 11 Alignment: DHTAATTAWWTADWDH TTTTTTTTTTT----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- aaCAAAAACaa Combined Motif Original Motif Reverse Complement TTTWTTTWTTTADWDH HTGTTTTTGHH TTTWTKTTTTTRDHDH Direction: Forward Position #: 4 Overlap #: 11 Alignment: TTTWTTTWTTTADWDH ---HTGTTTTTGHH-- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Combined Motif yrTGTGCACAyr Original Motif Reverse Complement TTTWTKTTTTTRDHDH BBTGTGCACAVV DKTKTKYACAHHTTTW Direction: Backward Position #: 1 Overlap #: 12 Alignment: TTTWTKTTTTTRDHDH ----BBTGTGCACAVV ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Results created by MOTIFSIM on 06-18-2018 15:30:26 Runtime: 835.059 seconds MOTIFSIM is written by Ngoc Tam L. 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